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https://www.readbyqxmd.com/read/28209559/irreversible-electroporation-for-the-ablation-of-renal-cell-carcinoma-a-prospective-human-in-vivo-study-protocol-ideal-phase-2b
#1
Mara Buijs, Krijn P van Lienden, Peter Gk Wagstaff, Matthijs Jv Scheltema, Daniel M de Bruin, Patricia J Zondervan, Otto M van Delden, Ton G van Leeuwen, Jean Jmch de la Rosette, M Pilar Laguna
BACKGROUND: Irreversible electroporation (IRE) is an emerging technique delivering electrical pulses to ablate tissue, with the theoretical advantage to overcome the main shortcomings of conventional thermal ablation. Recent short-term research showed that IRE for the ablation of renal masses is a safe and feasible treatment option. In an ablate and resect design, histopathological analysis 4 weeks after radical nephrectomy demonstrated that IRE-targeted renal tumors were completely covered by ablation zone...
February 16, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28191497/carbon-dioxide-versus-room-air-insufflation-during-balloon-assisted-enteroscopy-a-systematic-review-with-meta-analysis
#2
Ashok Shiani, Seth Lipka, Andrew Lai, Andrea C Rodriguez, Christian M Andrade, Ambuj Kumar, Patrick Brady
Background and study aims Carbon dioxide (CO2) insufflation has been suggested to be an ideal alternative to room air insufflation to reduce trapped air within the bowel lumen after balloon assisted enteroscopy (BAE). We performed a systematic review and meta-analysis to assess the safety and efficacy of utilizing CO2 insufflation as compared to room air during BAE. Patients and methods The primary outcome is mean change in visual analog scale (VAS; 10 cm) at 1, 3, and 6 hours to assess pain. Secondary outcomes include insertion depth (anterograde or retrograde), adverse events, total enteroscopy rate, diagnostic yield, mean anesthetic dosage, and PaCO2 at procedure completion...
January 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28188978/split-dose-bowel-preparation-with-polyethylene-glycol-for-colonoscopy-performed-under-propofol-sedation-is-there-an-optimal-timing
#3
Alaa Alghamry, Sureshkumar K Ponnuswamy, Aditya Agarwal, Hadi Moattar, Stephanie T Yerkovich, Ann E Vandeleur, James Thomas, John Croese, Tony Rahman, Ruth Hodgson
AIM: Aspiration risk, especially with propofol sedation, remains a concern with split-dose bowel preparation using polyethylene glycol, which involves up to one liter of preparation intake close to the procedure time. We aim to identify the ideal timing of bowel preparation that achieves optimal colon cleansing with no increased risk of aspiration in all patients undergoing combined esophagogastroduodenoscopy (EGD) and colonoscopy with propofol sedation. METHODS: We prospectively recruited 892 consecutive patients undergoing simultaneous EGD and colonoscopy...
February 11, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28178371/an-explanatory-study-on-the-concept-of-nursing-presence-from-the-perspective-of-patients-admitted-to-hospitals
#4
Fatemeh Mohammadipour, Foroozan Atashzadeh-Shoorideh, Soroor Parvizy, Meimanat Hosseini
AIMS AND OBJECTIVES: The aim of this study is to clarify the concept of nursing presence through patients' perception. BACKGROUND: The holistic caring process at the bedside must incorporate the concept of nursing presence. Most of the research about nursing presence is based on nurses' experiences and research into patients' experiences is minimal. According to goals of patient-centeredness, the association between the patient satisfaction and nursing presence, and patients' ability to understand this concept, it is important to explore this concept from the patients' perspective...
February 8, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28174659/making-an-impakt-improving-care-of-chronic-kidney-disease-patients-in-the-community-through-collaborative-working-and-utilizing-information-technology
#5
Gang Xu, Rupert Major, David Shepherd, Nigel Brunskill
Chronic kidney disease (CKD) is a serious long-term condition, which if left untreated causes significant cardiovascular sequele. It is well recognized management of modifiable risk factors, such as blood pressure (BP), can lead to improved long-term outcomes. A novel information technology (IT) solution presents a possible solution to help clinicians in the community identify and manage at risk patients more efficiently. The IMproving Patient care and Awareness of Kidney disease progression Together (IMPAKT) IT tool was used to identify patients with CKD and uncontrolled hypertension in the community...
2017: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/28161483/onlay-with-adhesive-use-compared-to-sublay-mesh-placement-in-ventral-hernia-repair-was-chevrel-right-an-americas-hernia-society-quality-collaborative-analysis
#6
Ivy N Haskins, Guy R Voeller, Nathaniel F Stoikes, David L Webb, Robert G Chandler, Sharon Phillips, Benjamin K Poulose, Michael J Rosen
BACKGROUND: The use of mesh during ventral hernia repair (VHR) is a well-accepted concept. However, the ideal location of mesh placement remains heavily debated. While VHR with onlay mesh placement has been historically associated with a high rate of wound events, this surgical approach is technically less challenging than VHR with sublay mesh placement. The purpose of this study is to compare onlay mesh placement with adhesive fixation to sublay mesh placement 30-day wound events using the Americas Hernia Society Quality Collaborative (AHSQC) database...
February 1, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28155017/implementing-standardized-inter-unit-communication-in-an-international-setting-handoff-of-patients-from-emergency-medicine-to-internal-medicine
#7
Kamna S Balhara, Susan M Peterson, Mohamed Moheb Elabd, Linda Regan, Xavier Anton, Basil Ali Al-Natour, Yu-Hsiang Hsieh, James Scheulen, Sarah A Stewart de Ramirez
Standardized handoffs may reduce communication errors, but research on handoff in community and international settings is lacking. Our study at a community hospital in the United Arab Emirates characterizes existing handoff practices for admitted patients from emergency medicine (EM) to internal medicine (IM), develops a standardized handoff tool, and assesses its impact on communication and physician perceptions. EM physicians completed a survey regarding handoff practices and expectations. Trained observers utilized a checklist based on the Systems Engineering Initiative for Patient Safety model to observe 40 handoffs...
February 3, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28144694/-nationwide-survey-among-institutes-of-microbiology-in-academic-medicine-is-the-interdisciplinary-approach-the-right-way-to-treat-patients-with-urogenital-infections
#8
L Schneidewind, J Kranz, D Schlager, A E Pelzer
BACKGROUND: Increasing antibiotic resistance is a current and severe problem in medicine, especially in urology. Multidisciplinary antibiotic stewardship programmes are an important approach to counteract increasing resistance rates. This approach includes collaboration between urologists and microbiologists. OBJECTIVES: The primary endpoint was to describe the current setting of interdisciplinary work of urologists and microbiologists in university hospitals in Germany...
January 31, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28135034/using-collaborative-two-stage-examinations-to-address-test-anxiety-in-a-large-enrollment-gateway-course
#9
Kimberly A Fournier, Jannelle Couret, Jason B Ramsay, Joshua L Caulkins
Large enrollment foundational courses are perceived as "high stakes" because of their potential to act as barriers for progression to the next course or admittance to a program. The nature of gateway courses makes them ideal settings to explore the relationship between anxiety, pedagogical interventions, and student performance. Here, two-stage collaborative examinations were implemented to improve test-taking skills and address widespread test anxiety in an introductory human anatomy course. Test anxiety data were collected (using the Motivated Strategies for Learning Questionnaire) before the first examination and last examination...
January 30, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28128008/introduction-of-high-risk-medical-devices-national-measures-that-can-be-taken-under-the-current-european-legislation-to-put-the-patient-interest-central
#10
Mattias Neyt, Hanne Baeyens, Céline Pouppez, Pierre Slegers, Frank Hulstaert, Sabine Stordeur, Irm Vinck
BACKGROUND: High-risk medical devices may not always provide a therapeutic added value to patients. In Europe, no proof of efficacy is required to receive a CE label, making it difficult for policymakers to decide on reimbursement of (often expensive) high-risk medical devices. We explore, within the framework of the European legislation, the possibilities at a national level for a guided introduction of such devices. RESEARCH DESIGN AND METHODS: HTA and legal experts worked in close collaboration with medical specialists and government representatives making a legal analysis of what is possible under the (revised) European and national legislation...
January 27, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28125127/-the-tug-of-war-in-healthcare-psychologists-conception-and-practice-concerning-matrix-based-support-in-the-center-for-family-health-support
#11
Ana Paula Klein, Ana Flávia Pires Lucas d'Oliveira
The current study analyzed the conception and practice of matrix-based support among psychologists working at the Center for Family Health Support (NASF in Portuguese) in the city of São Paulo, Brazil. A qualitative methodology was used with semi-structured interviews that were taped, transcribed, and submitted to thematic content analysis. The study revealed dilemmas between the work as prescribed and what is possible to achieve in practice, and between idealization of the collaborative proposal and its implementation...
January 23, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28116774/beyond-the-consultation-room-proposals-to-approach-health-promotion-in-primary-care-according-to-health-care-users-key-community-informants-and-primary-care-centre-workers
#12
Anna Berenguera, Mariona Pons-Vigués, Patricia Moreno-Peral, Sebastià March, Joana Ripoll, Maria Rubio-Valera, Haizea Pombo-Ramos, Angela Asensio-Martínez, Eva Bolaños-Gallardo, Catalina Martínez-Carazo, José Ángel Maderuelo-Fernández, Maria Martínez-Andrés, Enriqueta Pujol-Ribera
BACKGROUND: Primary health care (PHC) is the ideal setting to provide integrated services centred on the person and to implement health promotion (HP) activities. OBJECTIVE: To identify proposals to approach HP in the context of primary care according to health-care users aged 45-75 years, key community informants and primary care centre (PCC) workers. METHODS: Descriptive-interpretive qualitative research with 276 participants from 14 PCC of seven Spanish regions...
January 24, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28068998/a-qualitative-study-on-african-immigrant-and-refugee-families-experiences-of-accessing-primary-health-care-services-in-manitoba-canada-it-s-not-easy
#13
Roberta Lynn Woodgate, David Shiyokha Busolo, Maryanne Crockett, Ruth Anne Dean, Miriam R Amaladas, Pierre J Plourde
BACKGROUND: Immigrant and refugee families form a growing proportion of the Canadian population and experience barriers in accessing primary health care services. The aim of this study was to examine the experiences of access to primary health care by African immigrant and refugee families. METHODS: Eighty-three families originating from 15 African countries took part in multiple open ended interviews in western Canada. Qualitative data was collected in six different languages between 2013 and 2015...
January 9, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28050745/an-evolving-ecosystem-for-natural-language-processing-in-department-of-veterans-affairs
#14
Jennifer H Garvin, Megha Kalsy, Cynthia Brandt, Stephen L Luther, Guy Divita, Gregory Coronado, Doug Redd, Carrie Christensen, Brent Hill, Natalie Kelly, Qing Zeng Treitler
In an ideal clinical Natural Language Processing (NLP) ecosystem, researchers and developers would be able to collaborate with others, undertake validation of NLP systems, components, and related resources, and disseminate them. We captured requirements and formative evaluation data from the Veterans Affairs (VA) Clinical NLP Ecosystem stakeholders using semi-structured interviews and meeting discussions. We developed a coding rubric to code interviews. We assessed inter-coder reliability using percent agreement and the kappa statistic...
February 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28048872/we-fg-bra-10-radiodosimetry-of-a-novel-alpha-particle-therapy-targeted-to-uveal-melanoma-absorbed-dose-to-organs-in-mice
#15
Christopher J Tichacek, Narges K Tafreshi, Mikalai M Budzevich, Epifanio Ruiz, Thaddeus J Wadas, Mark L McLaughlin, Eduardo G Moros, David L Morse
PURPOSE: The melanocortin-1 receptor (MC1R) is expressed in 94% of uveal melanomas and is described as an ideal target for this untreatable disease. MC1RL is a high affinity MC1R specific peptidomimetic ligand that can serve as a scaffold for therapeutic conjugates such as alpha particle emitting isotopes. The purpose of this study was to assess normal tissue distribution and risk as a result of using the DOTA chelator conjugated to MC1RL to deliver (225) Ac: MC1RL-DOTA-(225) Ac. METHODS: 17 non-tumor bearing BALB/c mice were intravenously injected with the novel MC1RL-DOTA-(225) Ac radiopharmaceutical with an average initial administered activity of 2...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048364/we-fg-207a-01-introduction-to-dedicated-breast-ct-early-studies
#16
S Vedantham
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047717/we-fg-207a-02-why-we-need-breast-ct-clinical-perspective
#17
A O'Connell
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047520/we-fg-207a-05-dedicated-breast-ct-as-a-diagnostic-imaging-tool-physics-and-clinical-feasibility
#18
A Karellas
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047068/we-fg-207a-03-low-dose-cone-beam-breast-ct-physics-and-technology-development
#19
J Boone
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046464/su-d-201-07-a-survey-of-radiation-oncology-residents-training-and-preparedness-to-lead-patient-safety-programs-in-clinics
#20
M Spraker, M Nyflot, E Ford, G Kane, J Zeng, K Hendrickson
PURPOSE: Safety and quality has garnered increased attention in radiation oncology, and physicians and physicists are ideal leaders of clinical patient safety programs. However, it is not clear whether residency programs incorporate formal patient safety training and adequately equip residents to assume this leadership role. A national survey was conducted to evaluate medical and physics residents' exposure to safety topics and their confidence with the skills required to lead clinical safety programs...
June 2016: Medical Physics
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