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Michael O'Malley, Patrick J Reardon, Ayoosh Pareek, Aaron Krych, Michael J Stuart
Varus knee malalignment caused by medial compartment arthritis results in progressive asymmetric wear of the tibiofemoral joint. This wear can cause progressively painful gonarthrosis. Surgical methods to address varus knee malalignment include lateral closing-wedge proximal tibial osteotomy, medial opening-wedge osteotomy, and arthroplasty. Medial opening-wedge proximal tibial osteotomy is an effective procedure for restoring proper coronal alignment and reducing knee pain. In this technical note, we present a reproducible technique for proximal tibial osteotomy...
August 2016: Arthroscopy Techniques
Jessie Barbin, Bastien Moineau, Vincent Morin, Elodie Gailledrat, Dominique Saragaglia, Dominic Perennou
OBJECTIVE: The aim was to analyze the gait of knee osteoarthritis patients before osteotomy. MATERIAL/PATIENTS AND METHODS: Twenty-four patients aged 52.4 years±6.8, 15M/9F, were comparatively analyzed to 24 matched controls. Deficiencies and disabilities were evaluated by means of: numeric pain scale, Lysholm, Koos and Womac and SF-36 scores. They were also asked to estimate their self-perception of gait on a 4-level scale. Spatiotemporal gait parameters were also measured at comfortable speed, using an optical system (otpogait)...
September 2016: Annals of Physical and Rehabilitation Medicine
Diogo Luís Pereira, Hugo Lourenço Meleiro, Inês Araújo Correia, Sara Fonseca
BACKGROUND AND OBJECTIVES: Total knee arthroplasty and total hip arthroplasty are associated with chronic pain development. Of the studies focusing on perioperative factors for chronic pain, few have focused on the differences that might arise from the anesthesia type performed during surgery. METHODS: This was a prospective observational study performed between July 2014 and March 2015 with patients undergoing unilateral elective total knee arthroplasty (TKA) or total hip arthroplasty (THA) for osteoarthritis...
September 14, 2016: Revista Brasileira de Anestesiologia
Jean-Noël Argenson, Sébastien Parratte, Matthieu Ollivier
Often linked to sequelae of a knee injury or knee deformities, gonarthrosis is the most frequent form of osteoarthritis of the limbs. A variety of methods and therapies can be used to treat it. For advanced conditions, treatment may involve partial or total replacement.
August 2016: Revue de L'infirmière
Fabrício Bolpato Loures, Rogério Franco de Araújo Góes, Pedro José Labronici, João Maurício Barretto, Beni Olej
OBJECTIVE: To evaluate the relationship between patients' body mass index (BMI) and the degree of radiographic severity of knee osteoarthrosis. METHOD: 117 patients with gonarthrosis were evaluated prospectively. The patients' BMI was calculated and their knee arthrosis was classified in accordance with the modified Ahlbäck criteria. Kruskal-Wallis analysis of variance (ANOVA) was used to evaluate the relationship between these two variables. RESULTS: The group classified as Ahlbäck grade V had significantly higher BMI than the others...
July 2016: Revista Brasileira de Ortopedia
Michael J Neil, Jereme B Atupan, Juan Paulo L Panti, Robert A J Massera, Stewart Howard
BACKGROUND: For patients with knee osteoarthritis, even slight anatomical variations in the femur or the tibia could affect total limb alignment during total knee replacement (TKR). Our hypothesis implies that the femoral valgus correction angle (VCA) in patients indicated for TKR, is variable and higher than the reported norm of 6° utilized in most intramedullary instrumentation systems, and that tibial bowing may result to a disparity of the tibial mechanical axis to the anatomical axis...
December 2016: Journal of Orthopaedics
L A Shpagina, S G Abramovich, V A Drobyshev, L A Panacheva, E V Titskaya, G G Reshetova
Complex treatment using naphthalane applications with nonselective chromotherapy covered 64 engine operators of locomotive crews, aged 40-69 years, having 1-3 stage knee osteoarthrosis. Findings are that optimized treatment schedules effectively reduce intensity of pain, improve functional state of the joints involved, increase life quality of the patients, have no side effects. Comparative analysis of the treatment results showed that efficiency of combined naphthalane and nonselective chromotherapy exceeds isolated naphthalane effects...
2016: Meditsina Truda i Promyshlennaia Ekologiia
Seyit Ali Gumustas, İbrahim Yilmaz, Mehmet Isyar, Duygu Yasar Sirin, Ahmet Guray Batmaz, Ali Akin Ugras, Kadir Oznam, Zafer Ciftci, Mahir Mahirogullari
BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed to relieve pain and inflammation. These NSAIDs have also analgesic effects and can be administered via oral, injectable, and topical routes. During inflammation, a number of synovial mediators and cytokines are released which decrease the pH level of the synovial fluid. Administration of acidic NSAIDs further decreases the pH levels and hence contributes to the destruction of the cartilage. To our knowledge, no cellular-based study regarding the chondrotoxicity of phenyl alkanoic acid derivatives on NSAIDs was conducted before...
2016: Journal of Orthopaedic Surgery and Research
Benjamin V Herman, J Robert Giffin
High tibial osteotomy (HTO) has traditionally been used to treat varus gonarthrosis in younger, active patients. Varus malalignment increases the risk of progression of medial compartment osteoarthritis and an HTO can be performed to realign the mechanical axis of the lower limb towards the lateral compartment, thereby decreasing contact pressures in the medial compartment. Anterior cruciate ligament (ACL) insufficiency may lead to post-traumatic arthritis due to altered joint loading and associated injuries to the menisci and articular cartilage...
September 2016: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
Haluk Çabuk, Fatmagül Kuşku Çabuk, Ali Çağrı Tekin, Süleyman Semih Dedeoğlu, Murat Çakar, Cem Dinçay Büyükkurt
PURPOSE: Impaired proprioception accuracy of the knee has been proposed as a local factor in the onset and progression of knee osteoarthritis. Patients with decreased numbers of mechanoreceptors could be more likely to develop arthrosis due to a loss in proprioception of the joint. We aimed to identify and quantify the mechanoreceptors of the posterior cruciate ligament (PCL), the anterior capsule (AC) and the medial meniscocapsular junction (MCJ) in knee arthrosis. METHODS: PCLs, ACs and MCJs were harvested from 30 patients with Kellgren and Lawrence grades 3 and 4 osteoarthritis (OA), and ten knees taken from five cadavers without OA were used as a control group...
June 23, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Fabrício Bolpato Loures, Rogério Franco de Araújo Góes, Idemar Monteiro da Palma, Pedro José Labronici, José Mauro Granjeiro, Beni Olej
OBJECTIVE: To define the anthropometric profile of the knee in a Brazilian population with gonarthrosis using intraoperative measurements; and to evaluate the compatibility of three implants available for total knee arthroplasty. METHODS: Morphometric data were collected prospectively from 117 subjects with gonarthrosis. Six dimensions in the distal femur and two in the proximal tibia were documented in 118 knees while performing total arthroplasty. These data were compared with the dimensions of three implants available for total knee arthroplasty...
May 2016: Revista Brasileira de Ortopedia
V V Vnukov, S B Panina, N P Milyutina, I V Krolevets, M A Zabrodin
Analysis of polymorphisms of genes encoding antioxidant enzymes SOD1 (G7958A), SOD2 (T58C), CAT (C-262T), and GSTP1 (Ile105Val) in 93 patients with post-traumatic gonarthrosis showed that GSTP1 Ile105Val polymorphism is often associated with heterozygous mutation in catalase gene CAT C-262T. In gonarthrosis, catalase activity in peripheral blood mononuclear cells in patients with CT genotype of the C-262T locus of CAT gene more than 2-fold surpassed that in CC genotype and more than 50% surpassed the normal...
May 2016: Bulletin of Experimental Biology and Medicine
James D Wylie, Daniel L Jones, Melissa K Hartley, Ashley L Kapron, Aaron J Krych, Stephen K Aoki, Travis G Maak
PURPOSE: (1) To determine the radiographic correction/healing rate, patient-reported outcomes, reoperation rate, and complication rate after distal femoral osteotomy (DFO) for the valgus knee with lateral compartment pathology. (2) To summarize the reported results of medial closing wedge and lateral opening wedge DFO. METHODS: We conducted a systematic review of PubMed, MEDLINE, and CINAHL to identify studies reporting outcomes of DFOs for the valgus knee. Keywords included "distal femoral osteotomy," "chondral," "cartilage," "valgus," "joint restoration," "joint preservation," "arthritis," and "gonarthrosis...
June 3, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
Robert Klimkiewicz, Anna Kubsik, Katarzyna Janczewska, Agnieszka Jankowska, Marta Woldańska-Okońska
UNLABELLED: Gonarthrosis is the most important problem of contemporary medicine. Social and economic aspect of this phenomenon caused the World Health Organization gave it the status of "disease of civilization". AIM: The aim of the study was assessment of the impact chosen models of physiotherapy proceedings on the functional efficiency of patients with the gonarthrosis. MATERIALS AND METHODS: In the study took part in 120 patients of both sexes divided into 4 groups...
April 2016: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Aliye Yildirim Guzelant, Mehmet Isyar, İbrahim Yilmaz, Duygu Yasar Sirin, Selami Cakmak, Mahir Mahirogullari
AIM: The use of biological agents (BAs) for treating diseases such as rheumatoid arthritis (RA), spondyloarthropathy, and systemic lupus erythematosus to reduce inflammation has been fruitful. Especially as part of the increasing number of studies on the intra-articular application of BAs, the effects of BAs on cartilage have been widely investigated. In the present study, the effects of rituximab, abatacept, and adalimumab, all approved antirheumatic agents, on human primary chondrocytes were investigated comparatively and on the molecular level through viability, proliferation, and toxicity analyses...
April 15, 2016: Drug and Chemical Toxicology
Erman Ceyhan, Safa Gursoy, Mustafa Akkaya, Mahmut Ugurlu, Ismet Koksal, Murat Bozkurt
BACKGROUND: The aim of this pilot study was to analyze the data obtained from a retrospective examination of the records of the existing reimbursement system and through the identification of gaps in the data to create a foundation for a reliable, descriptive national registry system for our country. METHODS: The Social Security Institution Medical Messenger (MEDULA) records were scanned for the years 2010-2014, and the numbers of total knee arthroplasty applied for a diagnosis of gonarthrosis and the numbers of revision knee arthroplasty were recorded for the country in general...
September 2016: Journal of Arthroplasty
R L Espinosa-Mendoza, M Soto-Padilla, F Gómez-Garcia
BACKGROUND: The elderly represent a growing sector of the Mexican population and they are expected to outgrow the number of youths in the coming years. Musculoskeletal conditions are a major cause of disability among the elders; they affect up to 80%. In Mexico City 36% of the population uses private health care services. OBJECTIVE: To contribute with epidemiologic data about the frequency of musculoskeletal conditions and their hospital-based treatment in patients ages 65 and over admitted to a private hospital in Mexico City...
January 2015: Acta Ortopédica Mexicana
Özal Özcan, Mehmet Eroglu, Hakan Boya, Yilmaz Kaya
PURPOSE: Closed-wedge high tibial osteotomy (CW-HTO) requires shortening of the fibula or the fibular head or disruption of the proximal tibiofibular joint (PTFJ). However, no study has evaluated the proximal tibiofibular joint after the osteotomy. The aim of this study was to investigate the fate of the PTFJ after CW-HTO applied with using PTFJ disruption method. METHODS: This prospective study included 22 knees of 20 patients who underwent CW-HTO. The mean age of the patients was 50 ± 4 years, and the mean follow-up period was 27...
March 12, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Masamichi Yokoyama, Yasuhiro Nakamura, Toru Onishi, Koji Hirano, Motoyuki Doi
High tibial osteotomy (HTO) is a general procedure for the treatment of degenerative gonarthrosis. In recent years, it has been reported that opening wedge high tibial osteotomy (OWHTO) has become widespread with good results. Despite these facts, HTOs tend to be avoided due to the need for long-term postoperative treatment. To investigate the treatment period for total recovery (healing period) after OWHTO and the factors affecting it. There were 47 cases of medial type degenerative gonarthrosis who underwent OWHTO from 2008 through 2011...
2016: SpringerPlus
Thomas Haufe, Stefan Förch, Peter Müller, Johannes Plath, Edgar Mayr
The total knee arthroplasty (TKA) is the gold standard for patients with an advanced symptomatic gonarthrosis. However, there are very few publications dealing with the primary TKA for patients with a proximal tibia fracture. In our retrospective study we evaluated 30 patients treated with a TKA for a proximal tibia fracture in our institution between 01/2008 and 12/2014. We collected the following statistical data from each patient: age, classification of the fracture (AO-classification), type of prosthesis used, length of the operation and hospitalization, and complications during the follow-up...
2016: BioMed Research International
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