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Paule V Joseph, Sarah K Abey, Wendy A Henderson
Nutrition is a factor involved in inflammation and a modulator of risk toward some cancers, and the complexity of linkages between dietary components and epigenetics mechanisms (e.g., DNA methylation, histone modification, chromatin remodeling) may affect the inflammation phenotype and the development of cancer. An increasing number of studies support the role of diet in cancer development, prevention, and treatment. Although current knowledge regarding nutri-epigenetics is expanding, more work is needed, and nurse scientists have the potential to significantly contribute to the expansion of this knowledge...
November 1, 2016: Oncology Nursing Forum
Min-Jun Park, Ji-Hye Song, Myung-Soo Shon, Hae Ok Kim, O Jun Kwon, Seong-Soo Roh, Choon Young Kim, Gyo-Nam Kim
Obesity is a major risk factor for various metabolic diseases such as cardiovascular disease, hypertension, and type 2 diabetes mellitus. In this study, we prepared ethanol extracts from Agastache rugosa (ARE), Chrysanthemum zawadskii (CZE), Mentha arvensis (MAE), Perilla frutescens (PFE), Leonurus sibiricus (LSE), Gardenia jasminoides (GJE), and Lycopus coreanus (LCE). The anti-oxidant and anti-adipogenic effects were evaluated. The IC50 values for ascorbic acid and LCE against 2,2-diphenyl-1-picrylhydrazyl radicals were 246...
September 2016: Preventive Nutrition and Food Science
Jaroslav A Hubacek
Apolipoprotein A5 (APOA5) is a small protein, expressed predominantly in the liver. In plasma, it is located on triglyceride rich lipoprotein particles (chylomicrones and VLDL) and on HDL. Plasma concentration of apolipoprotein A5 is very low, suggesting rather regulatory (activation of lipoprotein lipase, …) than structural function. APOA5 is an important determinant of plasma triglyceride concentration; this effect has been confirmed both on animal models, as well as on human studies. Minor alleles of three commonly analysed variants within this gene (rs662799, rs3135506, rs2075291) are associated with higher plasma TG values and increased risk of myocardial infarction, with some important interethnic differences observed...
October 30, 2016: Gene
Peter M Chege, Zipporah W Ndungu, Betty M Gitonga
BACKGROUND: HIV and AIDS affect most the productive people, leading to reduced capacity to either produce food or generate income. Children under-fives are the most vulnerable group in the affected households. There exists minimal information on food security status and its effect on nutritional status of children under-fives in households affected by HIV and AIDS. The aim of this study was to assess food security and nutritional status of children under-five in households affected by HIV and AIDS in Kiandutu informal settlement, Kiambu County...
2016: Journal of Health, Population, and Nutrition
Julie Perinel, Christophe Mariette, Bertrand Dousset, Igor Sielezneff, Alain Gainant, Jean-Yves Mabrut, Sylvie Bin-Dorel, Michel El Bechwaty, Dominique Delaunay, Lorraine Bernard, Alain Sauvanet, Marc Pocard, Emmanuel Buc, Mustapha Adham
OBJECTIVES: The aim of this study was to compare nasojejunal early enteral nutrition (NJEEN) with total parenteral nutrition (TPN), after pancreaticoduodenectomy (PD), in terms of postoperative complications. BACKGROUND: Current nutritional guidelines recommend the use of enteral over parenteral nutrition in patients undergoing gastrointestinal surgery. However, the NJEEN remains controversial in patients undergoing PD. METHODS: Multicenter, randomized, controlled trial was conducted between 2011 and 2014...
November 2016: Annals of Surgery
Gerassimos Flabouraris, George Albert Karikas
Nutri-epigenetics has lately emerged as a new field in cancer epigenetic research. Cancer represents a multistage and heterogeneous disease that is driven by progressive genetic and epigenetic abnormalities. Epigenetic activity is influenced by several exogenous and endogenous factors including, nutrition, environment, disease, ethnicity, life style, medication, toxins, physical activity, age, gender and family genetics. Epigenetic therapy including mainly natural phenolics is a new area for drug development in cancer prevention...
January 2016: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
Priscila Nicolao Mazzola, Tatiele Nalin, Kamila Castro, Margreet van Rijn, Terry G J Derks, Ingrid D S Perry, Alberto Scofano Mainieri, Ida Vanessa D Schwartz
BACKGROUND: Phenylketonuria (PKU) is characterized by phenylalanine (Phe) accumulation to toxic levels due to the low activity of phenylalanine-hydroxylase. PKU patients must follow a Phe-restricted diet, which may put them in risk of nutritional disturbances. Therefore, we aimed to characterize body composition parameters and nutritional status in Brazilian PKU patients also considering their metabolic control. METHODS: Twenty-seven treated PKU patients older than 5 years, and 27 age- and gender-matched controls, were analyzed for anthropometric features and body composition by bioelectrical impedance (BIA)...
March 2016: Molecular Genetics and Metabolism Reports
Grzegorz Raszewski, Roman Chwedorowicz, Agnieszka Chwedorowicz, Katarzyna Gustaw Rothenberg
INTRODUCTION AND OBJECTIVE: Evidence for the benefit of antioxidants' based therapeutic intervention in dementia are inconsistent. Parallel studies in disease forms of dementia different than Alzheimer's are even less conclusive. In this study, the role of serum levels of homocysteine (tHcy), lipids and antioxidants in predicting the risk of cognitive decline in Alzheimer's disease (AD) versus non-Alzheimer's dementias (n-AD). The objective was to add to the ongoing cumulative research to establish the biochemical baseline for potential nutri-therapeutic intervention in different forms of dementia...
2016: Annals of Agricultural and Environmental Medicine: AAEM
Pauzi Nur Aimi Syarina, Govindarajan Karthivashan, Faridah Abas, Palanisamy Arulselvan, Sharida Fakurazi
Blue-green alga (Spirulina platensis) is a well renowned nutri-supplement due to its high nutritional and medicinal properties. The aim of this study was to examine the wound healing efficiency of Spirulina platensis at various solvent extracts using in vitro scratch assay on human dermal fibroblast cells (HDF). Various gradient solvent extracts (50 μg/ml of methanolic, ethanolic and aqueous extracts) from Spirulina platensis were treated on HDF cells to acquire its wound healing properties through scratch assay and in this investigation we have used allantoin, as a positive control to compare efficacy among the phytoextracts...
2015: EXCLI journal
Ding Li, Qi Zhong, Tingting Liu, Jufang Wang
In this work, water-soluble extracts of Ganoderma lucidum spores (Gls), a Chinese medicinal herb that possesses cell growth stimulating function, were found to be an effective growth factor for Chinese hamster ovary (CHO) cell cultivation. The Gls extract was prepared and supplemented to CHO K1 cell culture media with various serum levels. Our results obtained from both the static culture and the spinner-flask suspension culture showed that use of small-amount Gls extract effectively promoted cell growth and suppressed cell apoptosis induced by serum deprivation with normal cell cycle maintained in a low-serum medium...
June 2016: Bioprocess and Biosystems Engineering
Vincent W Vanek, Phil Ayers, Pamela Charney, Michael Kraft, Ronelle Mitchell, Steven Plogsted, Jason Soden, Charles W Van Way, Jacqueline Wessel, John Winter, Sue Kent, Peggy Turner, Jean Bouche, Donna Quirk, Douglas L Seidner
BACKGROUND: This is a follow-up survey to reassess the safety and efficacy of nutrition content in the available electronic health record (EHR) systems. MATERIALS AND METHODS: Members of the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.), American Society for Nutrition, and the Academy for Nutrition and Dietetics were asked to participate in an online survey. The survey included questions from a 2012 EHR survey on the safety and efficacy in 5 nutrition content areas as well as questions from previous 2003 and 2011 A...
June 2016: Nutrition in Clinical Practice
Sze Ying Leong, Indrawati Oey, David John Burritt
This research aimed to study the effect of pulsed electric field (PEF) processing on the bioprotective capacity of carrot purée for White Belgian, Yellow Solar, Nantes, Nutri Red and Purple Haze cultivars against H2O2-induced oxidative damage. The bioprotective capacity was determined using cell viability, membrane integrity and nitric oxide (NO) production in a human Caco-2 cell culture assay. Total carotenoids, total anthocyanins, total vitamin C and total phenolics were also evaluated. Compared to the untreated purée, Purple Haze and Nutri Red processed at 303 kJ/kg completely increased Caco-2 cells resistance towards oxidative damage by recovering the cell viability and inhibiting NO production...
April 1, 2016: Food Chemistry
Marie-Christine Turnin, Jean-Christophe Buisson, Namanjeet Ahluwalia, Laurent Cazals, Caroline Bolzonella-Pene, Caroline Fouquet-Martineau, Pascale Martini, Maïthé Tauber, Hélène Hanaire
OBJECTIVE: To evaluate the impact of interactive Nutri-Advice kiosks on children's nutritional skills and their ability to apply it to food choices in a middle school cafeteria menu (food choice competencies). DESIGN: Quasi-experimental design; pre/post-test. SETTING: Freestanding interactive computer terminals (kiosks) were installed in three middle schools in Toulouse, France. PARTICIPANTS: A total of 580 children were enrolled into the study (mean age, 13 ± 1 years)...
February 2016: Journal of Nutrition Education and Behavior
A Bocquet, M Vidailhet
Nutri-Baby SFAE 2013 is the 5th edition of a survey conducted every 8 years since 1981 by SFAE (Secteur Français des Aliments de l'Enfance) in collaboration with an opinion poll institute (SOFRES) for the feeding behavior part of the study and with CREDOC for calculating nutrient intake: 1,188 mothers of infants and young children from 15 days to 3 years of age were interviewed in 2013. The present paper is limited to the behavioral part of the investigation on the observance by mothers of pediatric recommendations...
October 2015: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
M-F Le Heuzey, C Turberg-Romain
This new study by the Secteur français des aliments de l'enfance (SFAE) (French Agency for Children's Foods) confirms the improvement in the nutritional environment of young children, particularly in sharing family meals. Incorporating the sample of breastfed children is a new feature, although food refusal behavior in infants did not appear to differ greatly whether or not they were being breastfed, and mothers expressed a need to be informed and guided in order for their children to better accept varied foods...
October 2015: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
G Tavoularis
The French Agency for Children's Foods (SFAE) has conducted a national survey on the eating behaviors and food consumption of children under 3 years of age every 8 years since 1981. A survey of this scope requires the involvement of many stakeholders with diverse skills (professionals in conducting studies and surveys, healthcare professionals and researchers such as pediatricians and nutrionists, sociologists and statisticians) before, during and after the completion of the survey. In 2013, the survey was repeated and focused on 1188 children aged 15 days to 35 months...
October 2015: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Kate Ducak, Heather Keller
PURPOSE: Few questionnaires to test nutrition knowledge and attitudes of older adults living independently in the community have been developed and tested to assess self-management tools such as Nutri-eSCREEN and other education programs. This study is a first step in the development of a questionnaire designed to evaluate the nutrition knowledge and attitudes of independent older adults (NAK-50+). METHODS: The steps involved in this study were: (i) drafting initial questions based on the content of the Nutri-eSCREEN education material, (ii) using cognitive interviewing to determine if these questions were understandable and relevant (n = 9 adults ≥50 years of age), and (iii) completing test-retest reliability in a convenient community sample (n = 60 adults ≥50 years of age)...
March 2016: Canadian Journal of Dietetic Practice and Research
Anne Rochtus, Katrien Jansen, Chris Van Geet, Kathleen Freson
Neural tube defects (NTDs), affecting 1-2 per 1000 pregnancies, are severe congenital malformations that arise from the failure of neurulation during early embryonic development. The methylation hypothesis suggests that folate prevents NTDs by stimulating cellular methylation reactions. Folate is central to the one-carbon metabolism that produces pyrimidines and purines for DNA synthesis and for the generation of the methyldonor S-adenosyl-methionine. This review focuses on the relation between the folate-mediated one-carbon metabolism, DNA methylation and NTDs...
2015: Mini Reviews in Medicinal Chemistry
Aida Malek Mahdavi, Reza Mahdavi, Mohammad Lotfipour, Mohammad Asghari Jafarabadi, Elnaz Faramarzi
BACKGROUND: This study was aimed to assess agreement and diagnostic accuracy of the Iranian version of Mini Nutritional Assessment short-form (MNA-SF) against the original MNA, as a gold standard in community-dwelling elderly. METHODS: The full MNA and 9-item MNA-SF comprising questions regarding clinical status, dietary assessment and self-perception of health status and nutri-tion together with mid-arm and calf circumference measurements without in-cluding the body mass index (BMI) were completed for 205 volunteers aged 65 or older recruited from all over Markazi Province (Iran)...
2015: Health Promotion Perspectives
Teresa A Giancaspero, Matilde Colella, Carmen Brizio, Graziana Difonzo, Giuseppina M Fiorino, Piero Leone, Roderich Brandsch, Francesco Bonomi, Stefania Iametti, Maria Barile
The primary role of the water-soluble vitamin B2 (riboflavin) in cell biology is connected with its conversion into FMN and FAD, the cofactors of a large number of dehydrogenases, oxidases and reductases involved in a broad spectrum of biological activities, among which energetic metabolism and chromatin remodeling. Subcellular localisation of FAD synthase (EC, FADS), the second enzyme in the FAD forming pathway, is addressed here in HepG2 cells by confocal microscopy, in the frame of its relationships with kinetics of FAD synthesis and delivery to client apo-flavoproteins...
2015: Frontiers in Chemistry
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