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Brain aneurism

P Fallahi, G Elia, R Foddis, A Cristaudo, A Antonelli
Scientific literature suggests a relationship between military occupation and the development of brain tumors, but no italian study has investigated on the impact of this job on the brain cancer morbidity. In this a study information were obtained from patients recruited in the Neurosurgical Department of the University-Hospital of Pisa, Italy, from 1990 to 1999. The study has been conducted as a case-control study. 161, newly diagnosed cases of brain tumors (glioma and meningiomas, histologically confirmed), were recruited, such as 483 controls (with other non tumoral neurologic diseases: trauma, hemorrhagic brain disorders, aneurism, etc), by matching cases and controls (1:3), for age (± 5 years) and gender...
November 2017: La Clinica Terapeutica
Rashid Alijani Ardeshir, Hossein Zolgharnein, Abdolali Movahedinia, Negin Salamat, Ebrahim Zabihi
Fipronil is an effective insecticide widely used in agriculture with potential ecotoxicological consequences. The median lethal dose (LD50) and concentration (LC50) of fipronil in 16.3 g Caspian white fish, Rutilus frisii kutum fingerlings were determined. To determine the LD50, a total of 133 fish were assigned to 19 tanks (7 fish/tank) including one control and 6 treatment groups (300, 450, 550, 650, 750, 850 mg/kg). Fish were injected intraperitoneally and monitored at 96 h. The LD50 of fipronil was 632 mg/kg suggesting it was slightly toxic to the Caspian white fish...
2017: Toxicology Reports
A A Kalinkin, S S Petrikov, L T Khamidova, V V Krylov
AIM: To determine a prognostic role of leukocyte count in the venous blood in the acute stage of cerebral aneurysm (CA) rupture. MATERIAL AND METHODS: Fifty-one patients with CA rupture, aged from 20 to 65 years, hospitalized in the first 72 h over the period from 01.10.12 to 01.02.16 were examined. The severity of disease and anatomical form of hemorrhage was corresponded to III-IV degree on the W. Hunt - R. Hess scale and Fisher scale. All patients underwent surgery...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Jasminka Djelilovic-Vranic, Vanja Basic-Kes, Merita Tiric-Campara, Edina Djozic, Jasmin Kulenovic
INTRODUCTION: Subarachnoid hemorrhage (SAH)represents hemorrhage in the space between arachnoidea and pia mater, due to aneurysm burst, spontaneously or as a consequence of trauma. It is condition that occurs more common in women than men, and its most common complications are rebleeding and vazospasm. As a result of vasospasm, develops ischemia in the portion of brain tissue that can cause additional neurological deficit. Transcranial Doppler Sonography (TCD) is a noninvasive ultrasound diagnostic method that allows monitoring of the state of intracerebral hemodynamics...
March 2017: Acta Informatica Medica: AIM
W Li, L Huang, J Zeng, W Lin, K Li, J Sun, W Huang, J Chen, G Wang, Q Ke, J Duan, X Lai, R Chen, M Liu, Y Liu, T Wang, X Yang, Y Chen, H Xia, A P Xiang
The enteric nervous system (ENS) is recognized as a second brain because of its complexity and its largely autonomic control of bowel function. Recent progress in studying the interactions between the ENS and the central nervous system (CNS) has implicated alterations of the gut/brain axis as a possible mechanism in the pathophysiology of autism spectrum disorders (ASDs), Parkinson's disease (PD) and other human CNS disorders, whereas the underlying mechanisms are largely unknown because of the lack of good model systems...
October 25, 2016: Molecular Psychiatry
F Heran Dreyfus, O Galatoire, P Koskas, F Lafitte, E Nau, O Bergès
Orbito-palpebral vascular pathology represents 10% of all the diseases of this area. The lesion may be discovered during a brain CT scan or MRI, or because it causes clinical symptoms such as orbital mass, visual or oculomotor alteration, pain, proptosis, or acute bleeding due to a complication of the lesion (hemorrhage, thrombosis). We present these lesions using an anatomical, clinical, imaging and therapeutic approach. We distinguish four different entities. Vascular tumors have common imaging characteristics (hypersignal on T2 sequence, contrast enhancement, abnormal vascularization well depicted with ultrasound and Doppler, and possible bleeding)...
November 2016: Journal Français D'ophtalmologie
Neeraj Kumar, K Ambasankar, K K Krishnani, S K Gupta, Shashi Bhushan, P S Minhas
This study investigated 96h median lethal concentration of endosulfan (99%, pure α: β ratio of 7:3) by conducting static non-renewable acute toxicity bio-assay in Chanos chanos juvenile with average weight (110±5.65g). Further, the effect of different definitive doses (18.5, 19.5, 20.5, 21.5 and 22.5µg/L) of endosulfan on metabolic, heamato-immunoligcal and histopathological response were probed. Anti-oxidative enzymes CAT, SOD and GST showed significant (p<0.01) increase of activity in the liver, gill and brain during exposure to endosulfan in a dose and time dependent manner...
September 2016: Ecotoxicology and Environmental Safety
Guillermo Enrique Vergara, Natalia Roura, Marcelo Del Castillo, Andrea Mora, Santiago Condomi Alcorta, Rubén Mormandi, Andrés Cervio, Jorge Salvat
BACKGROUND: Invasive aspergillosis (IA) of the central nervous system (CNS) is an uncommon condition that usually occurs in immunocompromised patients. This illness can manifest as meningitis, or as a micotic aneurism, stroke or abscess. The infection affects the CNS either primarily or, more often, secondarily via blood dissemination from a distant focus, and has a poor prognosis. We present a patient with IA primarily affecting the cervical bones, with later spread into the brain. CASE DESCRIPTION: A 25-year old male was receiving chemotherapy for acute lymphocytic leukemia when he developed pneumonitis secondary to methotrexate and was started on corticosteroids...
2015: Surgical Neurology International
Andrea Barp, Marny Fedrigo, Filippo Maria Farina, Sandro Lepidi, Francesco Causin, Chiara Castellani, Giacomo Cester, Gaetano Thiene, Marialuisa Valente, Claudio Baracchini, Annalisa Angelini
AIM: IgG4-related disease is a systemic disease that involves organs and vascular structures, in particular, the aorta. This is the first case that showed the carotid artery involvement with dissection evolution. METHODS AND RESULTS: In a 67-year-old man with speech impairment and right-hand clumsiness, a brain computed tomography revealed signs of acute ischemia in the left frontal lobe while an echo-color Doppler sonography of the cervical vessels showed a tight stenosis of left internal carotid artery with a large pseudoaneurysm...
January 2016: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
A N Konovalov, Yu M Filatov, T P Tissen, Sh Sh Eliava, S B Yakovlev, I N Pronin, D Yu Usachev, A V Golanov, V A Lukshin, S R Arustamyan, A Kheyreddin, O D Shekhtman, I A Sazonov, S A Maryashev, O B Belousova, A E Korshunov, Yu V Pilipenko, A V Shmigelsky
Theoretical and practical aspects of the complex treatment of brain and spinal vascular diseases using microsurgical, endovascular and radiosurgical methods are considered. Authors present the data demonstrating that, due to the implementation of the program of development of vascular centers in the Russian Federation, considerable progress was made in the treatment of cerebral aneurisms and hemorrhagic stroke. In author's opinion, wide introduction of surgical methods in the treatment of occlusive lesions of the blood vessels supplying the brain is needed...
2015: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
S O Lytvak, M V Ieleĭnik
Hemorrhagic insult (HI) with formation of intracranial hemorrhage of various anatomic form constitutes a typical clinical sign of the brain arterial aneurism rupture. Surgical intervention is the only one method of treatment in such patients. Some of them need performance of a one-staged or multi-staged operative interventions, directed on devascularization of the brain arterial aneurisms, evacuation or drainage of intracranial hemorrhage. One of physiological and perspective methods of clinical situation improvement is a local fibrinolytic therapy (LFTH) in complex of surgical treatment of the brain arterial aneurisms...
December 2014: Klinichna Khirurhiia
Giancarlo D'Andrea, Alessandro Frati, Andrea Pietrantonio, Pietro Familiari, Antonino Raco, Luigi Ferrante
INTRODUCTION: The BrainSuite(®) is a highly integrated operating theater designed mainly for brain tumor surgery. The issues concerning its routine use in vascular neurosurgery have not been discussed in literature to date. We report our experience of surgical treatment of cerebral aneurysms in the BrainSuite(®), with a view to evaluating safety, feasibility, advantages, disadvantages, and contraindications. MATERIAL AND METHODS: Retrospectively, we reviewed all the patients affected by ruptured and unruptured aneurysms that underwent craniotomy with clipping between January 2007 and May 2013 and a subsequent minimum 12-month follow up...
June 2015: Clinical Neurology and Neurosurgery
Quan Findlay, Kiryu K Yap, Annette J Bergner, Heather M Young, Lincon A Stamp
Gut motility disorders can result from an absent, damaged, or dysfunctional enteric nervous system (ENS). Cell therapy is an exciting prospect to treat these enteric neuropathies and restore gut motility. Previous studies have examined a variety of sources of stem/progenitor cells, but the ability of different sources of cells to generate enteric neurons has not been directly compared. It is important to identify the source of stem/progenitor cells that is best at colonizing the bowel and generating neurons following transplantation...
October 1, 2014: American Journal of Physiology. Gastrointestinal and Liver Physiology
Giorgio Fratus, Fabio Tagliabue, Pierpaolo Mariani, Enrico Coppola Bottazzi, Luisella Spinelli, Lorenzo Novellino
UNLABELLED: Lung cancer is the most common neoplasm diagnosed worldwide. Metastatic presentation of the disease is frequent. Apart from the usual sites of metastatic disease (bone, adrenals, liver, brain), a particular site for metastases is represented by skin. The case we report is about a 66 year-old man with cutaneous metastasis from lung cancer. A 66 year-old man, with a previous history of abdominal aortic aneurism, chronic obstructive pulmonary disease, cardiopathy, diabetes mellitus, was admitted to our institution for left lower lobe lung cancer...
July 21, 2014: Annali Italiani di Chirurgia
Iu V Pilipenko, Sh Sh Éliava, S B Iakovlev, O B Belousova, S B Buklina, S R Arustomian, K G Mikeladze, A A Bondarenko, A E Bykanov
UNLABELLED: Most patients with brain aneurisms were operated on in the late posthemorrhagic period at the Burdenko Neurosurgical Institute. OBJECTIVE: To investigate the rate and structure of complications of microsurgical and endovascular surgery for different topographic anatomic variants of cerebral aneurysms in patients operated on in the late posthemorrhagic period in order to assess the risk of intervention in these patients. MATERIAL AND METHODS: The study group comprised 1074 patients with single brain aneurysms who had been treated at the Burdenko Neurosurgical Institute (Russian Academy of Medical Sciences) for the period from 2005 to 2012...
2014: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
Hisato Nakazawa, Osamu Yamamuro, Yukio Uchiyama, Masataka Komori
In gamma knife stereotactic radiosurgery (GKSRS) treatment planning, 1.5 tesla (T)-magnetic resonance imaging (MRI) is normally used to identify the target lesion. Image artifacts and distortion arise in MRI if a titanium clip is surgically implanted in the brain to treat cerebral aneurysm. 3-T MRI scanners, which are increasingly being adopted, provide imaging of anatomic structures with better clinical usefulness than 1.5-T MRI machines. We investigated signal defects and image distortions both close to and more distant from the titanium clip in 1...
June 2014: Nihon Hoshasen Gijutsu Gakkai Zasshi
Sonia Kartha, Martha E Zeeman, Hassam A Baig, Benjamin B Guarino, Beth A Winkelstein
STUDY DESIGN: In vivo study defining expression of the neurotrophins, brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), in cervical intervertebral discs after painful whole-body vibration (WBV). OBJECTIVE: The goal of this study is to determine if BDNF and NGF are expressed in cervical discs after painful WBV in a rat model. SUMMARY OF BACKGROUND DATA: WBV is a possible source of neck pain and has been implicated as increasing the risk for disc disorders...
September 1, 2014: Spine
Airazat M Kazaryan, Joachim Wiborg, Kristin Hauss, Tommy K Anundsen, Olav J Flemmen, Thor Erik Holm, Giedrius Lauzikas
PATIENT: Female, 28 FINAL DIAGNOSIS: Rupture of the splenic artery aneurysm Symptoms: Hypovolemic shock Medication: - Clinical Procedure: - Specialty: Surgery. OBJECTIVE: Rare disease. BACKGROUND: ATLS principles have become a standard of care for trauma patients. However, there is poor documentation in regard to spontaneous non-traumatic life-threatening bleedings. CASE REPORT: Two women, a 21-year-old and a 28-year-old, presented to the admissions department in hemorrhagic shock...
2014: American Journal of Case Reports
Iu V Titova, S S Petrikov, A A Solodov, V V Krylov
The article contains results of examination of correlation between systemic hemodynamic and brain oxygenation and metabolism in patients with intracranial hemorrhage. Cardiac index (CI) and cerebral perfusion pressure (CPP) levels were compared to brain oxygenation and metabolism in 8 patients with intracranial hemorrhage (137 measurements). CI alterations didn't influence on PbrO2, glucose level or lactate/pyruvate ratio in the brain interstitial fluid in patients with traumatic brain injury. CPP elevation led to cerebral metabolism improvement...
July 2013: Anesteziologiia i Reanimatologiia
D Romanescu, E Gangone, M P Sirbu Boeti, R Zamfir, S O Dima, I Popescu
The pancreas procurement from brain-dead donors used for pancreatic islet isolation and transplantation, was analyzed between 2007-2012. The pancreas was transported to the Fundeni Clinical Institute and the islet isolation process was performed in the Cell Therapy Laboratory. There were 20 en bloc pancreas-duodenum-spleen procurement during multiorgan harvesting. Eighteen pancreata were used for islet isolation and two were used for whole pancreas transplantation.One pancreas was used for whole pancreas transplant alone and the other one was used for simultaneous pancreas and kidney transplantation...
May 2013: Chirurgia
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