keyword
MENU ▼
Read by QxMD icon Read
search

cardiac attack

keyword
https://www.readbyqxmd.com/read/29770487/inhibitory-effect-of-melatonin-on-necroptosis-via-repressing-the-ripk3-pgam5-cypd-mptp-pathway-attenuates-cardiac-microvascular-ischemia-reperfusion-injury
#1
Hao Zhou, Dandan Li, Pingjun Zhu, Qiang Ma, Toan Sam, Jin Wang, Shunying Hu, Yundai Chen, Yingmei Zhang
The molecular features of necroptosis in cardiac ischemia reperfusion (IR) injury have been extensively explored. However, there have been no studies investigating the physiological regulatory mechanisms of melatonin acting on necroptosis in cardiac IR injury. This study was designed to determine the role of necroptosis in microvascular IR injury, and investigate the contribution of melatonin in repressing necroptosis and preventing IR-mediated endothelial system collapse. Our results demonstrated that Ripk3 was primarily activated by IR injury and consequently aggravated endothelial necroptosis, microvessel barrier dysfunction, capillary hyperpermeability, the inflammation response, microcirculatory vasospasms and microvascular perfusion defects...
May 16, 2018: Journal of Pineal Research
https://www.readbyqxmd.com/read/29752776/influence-of-prehospital-airway-management-on-neurological-outcome-in-patients-transferred-to-a-heart-attack-centre-following-out-of-hospital-cardiac-arrest
#2
Timothy Edwards, Julia Williams, Michaela Cottee
OBJECTIVE: To describe the association between prehospital airway management and neurological outcomes in patients transferred by the ambulance service directly to a heart attack centre (HAC) post-return of spontaneous circulation (ROSC). METHODS: A retrospective observational cohort study in which ambulance records were reviewed to determine prehospital airway management strategy and collect physiological and demographic data. HAC notes were obtained to determine in-hospital management and quantify neurological outcome via the cerebral performance category (CPC) scale...
May 11, 2018: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29747915/prognostic-and-practical-validation-of-current-definitions-of-myocardial-infarction-associated-with-percutaneous-coronary-intervention
#3
Pierluigi Tricoci, L Kristin Newby, Robert M Clare, Sergio Leonardi, C Michael Gibson, Robert P Giugliano, Paul W Armstrong, Frans Van de Werf, Gilles Montalescot, David J Moliterno, Claes Held, Philip E Aylward, Lars Wallentin, Robert A Harrington, Eugene Braunwald, Kenneth W Mahaffey, Harvey D White
OBJECTIVES: In 13,038 patients with non-ST-segment elevation acute coronary syndrome undergoing index percutaneous coronary intervention (PCI) in the EARLY ACS (Early Glycoprotein IIb/IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome) and TRACER (Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome) trials, the relationship between PCI-related myocardial infarction (MI) and 1-year mortality was assessed. BACKGROUND: The definition of PCI-related MI is controversial...
May 14, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29747088/blood-hydrogen-peroxide-break-down-activity-in-healthy-subjects-and-in-patients-at-risk-of-cardiovascular-events
#4
Roberto Carnevale, Cristina Nocella, Pasquale Pignatelli, Simona Bartimoccia, Lucia Stefanini, Stefania Basili, Marta Novo, Alessandra D'Amico, Vittoria Cammisotto, Daniele Pastori, Francesco Violi
BACKGROUND AND AIMS: Antioxidant status has been shown to be associated with cardiovascular events (CVEs). The aim of the study was to develop an assay measuring serum hydrogen peroxide (H2 O2 ) break-down activity (HBA) of healthy subjects (HS) and to validate it in a cohort of patients with atrial fibrillation (AF). METHODS: We developed the HBA assay in 121 HS and validated it in 842 AF patients. The occurrence of CVEs was registered and correlated with HBA in AF during a median follow-up of 30...
April 25, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29743025/risk-of-incident-atrial-fibrillation-in-patients-presenting-with-retinal-artery-or-vein-occlusion-a-nationwide-cohort-study
#5
Christine Benn Christiansen, Christian Torp-Pedersen, Jonas Bjerring Olesen, Gunnar Gislason, Morten Lamberts, Nicholas Carlson, Mathias Buron, Nikolai Juul, Gregory Y H Lip
BACKGROUND: The inter-relationships of atrial fibrillation (AF) to retinal vascular occlusions (whether retinal artery occlusion (RAO) or retinal venous occlusion (RVO)) remain unclear. It is unknown if a presentation of retinal artery or venous occlusions may indicate a new onset cardiac arrhythmia. To shed light on this association, we investigated the risk of new onset AF in patients with known RAO and RVO. METHODS: Patients with retinal occlusions from 1997 to 2011 were identified through Danish nationwide registries and matched 1:5 according to sex and age...
May 10, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29730481/age-threshold-for-proper-definition-of-premature-coronary-artery-disease-in-males
#6
REVIEW
Hasan A Abderrahman, Imad M Al-Abdallat, Ahmed K Idhair
BACKGROUND: There is no universally accepted definition for the cut point age before which atherosclerosis is considered "premature." This is a retrospective study aimed to utilize the medico legal autopsy information for finding a proper definition of the age threshold of premature atherosclerosis in males. OBJECTIVES: This work aimed to utilize autopsy reports data that were issued at Jordan University Hospital to evaluate age-related differences in the distribution of coronary atherosclerotic and myocardial lesions and the determination of the age threshold at which such differences became apparent in male deaths...
April 30, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29722860/oesophageal-injury-following-magnetically-guided-single-catheter-ablation-for-atrial-fibrillation-insights-from-the-magna-af-registry
#7
Dirk Bastian, Johannes Schwab, Karl-Theodor Steurer, Andrea Brinker-Paschke, Arno Boessenecker, Reinhard Doering, Zeynep Karakurt, Laura Vitali-Serdoz, Matthias Pauschinger, Konrad Göhl
Aims: Oesophagogastroduodenoscopy (OGD) after catheter ablation (CA) of atrial fibrillation (AF) revealed a high rate of procedure related oesophageal lesions. We hypothesized that magnetically guided CA with careful radiofrequency energy titration at the posterior left atrial (LA) wall limits the incidence of oesophageal tissue damage. Methods and results: As a part of the prospective "Remote MAGNetic catheter Ablation for Atrial Fibrillation" (MAGNA-AF) registry, 251 out of 266 consecutive patients underwent OGD after magnetically guided single-CA for AF...
May 1, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29713482/impact-of-periodontitis-as-representative-of-chronic-inflammation-on-long-term-clinical-outcomes-in-patients-with-atrial-fibrillation
#8
Sung Il Im, Jinho Heo, Bong Joon Kim, Kyoung-Im Cho, Hyun Su Kim, Jung Ho Heo, Jin Yong Hwang
Objectives: Relationship between atrial fibrillation (AF) and inflammation was shown in previous studies. However, there was limited data about the association between the periodontitis and AF in the long-term follow-up. The aim of this study was to evaluate the impact of periodontitis on long-term clinical outcomes in patients with AF. Methods: The Kosin University echocardiography, ECG and periodontitis database were reviewed from 2013 to 2015 to identify patients with AF...
2018: Open Heart
https://www.readbyqxmd.com/read/29701358/carotid-stenosis-in-cardiac-surgery-patients
#9
Pedro Pinto Sousa, Gabriela Teixeira, João Gonçalves, Carlos Veiga, Pedro Sá Pinto, Pedro Brandão, Alexandra Canedo, Luis Vouga, Rui Almeida
INTRODUCTION: Ischemic stroke is a potential perioperative complication after an open heart surgery (OHS). Whether a carotid stenosis or occlusion is associated with an increased risk of perioperative stroke in patients or just a risk factor has been a concern of intense debate in the literature. METHODS: We retrospectively analyzed patients submitted to OHS between January and December2016 with known asymptomatic carotid disease. The data from 85 consecutive patients undergoing coronary artery bypass grafting, valve replacement, or both was collected...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29698062/targeted-deletion-of-t-cell-s1p-receptor-1-ameliorates-cardiac-fibrosis-in-streptozotocin-induced-diabetic-mice
#10
Chowdhury S Abdullah, Zhu-Qiu Jin
Infiltration of T cells is associated with patients who have diabetes at an increased risk of heart attack. T-cell sphingosine 1-phosphate receptor 1 (S1P1 )-mediated signaling directs T lymphocyte trafficking. Effects of T-cell S1P1 activation on cardiac fibrosis in a murine diabetic model remain to be explored. For this purpose, conditional T-cell S1P1 knockout (TS1P1 KO) mice generated by crossing S1pr1 loxP/loxP mice with Lck-Cre mice were used in a model of streptozotocin-induced diabetic cardiomyopathy...
April 26, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/29688297/ten-year-association-of-coronary-artery-calcium-with-atherosclerotic-cardiovascular-disease-ascvd-events-the-multi-ethnic-study-of-atherosclerosis-mesa
#11
Matthew J Budoff, Rebekah Young, Gregory Burke, J Jeffrey Carr, Robert C Detrano, Aaron R Folsom, Richard Kronmal, Joao A C Lima, Kiang J Liu, Robyn L McClelland, Erin Michos, Wendy S Post, Steven Shea, Karol E Watson, Nathan D Wong
Aims: While coronary artery calcium (CAC) has been extensively validated for predicting clinical events, most outcome studies of CAC have evaluated coronary heart disease (CHD) rather than atherosclerotic cardiovascular disease (ASCVD) events (including stroke). Also, virtually all CAC studies are of short- or intermediate-term follow-up, so studies across multi-ethnic cohorts with long-term follow-up are warranted prior to widespread clinical use. We sought to evaluate the contribution of CAC using the population-based MESA cohort with over 10 years of follow-up for ASCVD events, and whether the association of CAC with events varied by sex, race/ethnicity, or age category...
April 23, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29683098/untargeted-metabolomics-in-the-discovery-of-novel-biomarkers-and-therapeutic-targets-for-atherosclerotic-cardiovascular-diseases
#12
Vi T Dang, Aric Huang, Geoff H Werstuck
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity worldwide. Four out of five CVD deaths are due to myocardial infarction or stroke. Despite many initiatives that have been established for CVD prevention and risk management, and new therapies to treat existing CVD, patients continue to die from cardiac events. Clearly, we need to identify new therapeutic targets and strategies. Early diagnosis of CVDs and identification of patients at high risk of developing adverse events would allow for timely intervention that prevents serious consequences or death...
April 20, 2018: Cardiovascular & Hematological Disorders Drug Targets
https://www.readbyqxmd.com/read/29629065/carotid-arterial-stent-implantation-follow-up-and-results-in-50-patients-preliminary-report
#13
Alireza Khosravi, Fereshteh Ziaee Bideh, Farshad Roghani, Mohammad Saadatnia, Fariborz Khorvash, Majid Nejati, Nastaran Khoshpour, Mohaddeseh Behjati
Background: Carotid artery stenting (CAS) is considered as a safe and effective procedure for treatment of carotid artery stenosis. Evaluation of this procedure's complications is essential for proper clinical decision-making. Objective: This study aimed to evaluate the cardiovascular events after CAS among our patients in Isfahan, Iran. Methods: This case-series study was conducted on fifty patients from December 2013 to May 2016. These patients were referred to the cardiology centers of Isfahan, Iran by a neurologist, for stenting of extracranial carotid arteries...
February 2018: Electronic Physician
https://www.readbyqxmd.com/read/29623019/clinical-presentation-of-atrial-myxomas-does-it-differ-in-left-or-right-sided-tumor
#14
Habib Khan, Sanjay Chaubey, Mohammed Mohsin Uzzaman, Yasir Iqbal, Fareeda Khan, Salman Butt, Ranjit Deshpande, Jatin Desai
Objective: This paper reports a 20 years' experience in the management of atrial myxomas at our institution. Apart from presenting our experience of their clinical presentation, surgical management, post-operative complication, and long-term follow-up we investigated any correlation between left and right sided tumor with their symptom of presentation. Materials and Methods: The data were retrospectively collected for patients between the period 1995 and 2015 from the hospital database...
January 2018: International Journal of Health Sciences
https://www.readbyqxmd.com/read/29621274/phenotype-and-biochemical-heterogeneity-in-late-onset-fabry-disease-defined-by-n215s-mutation
#15
L Lavalle, A S Thomas, B Beaton, H Ebrahim, M Reed, U Ramaswami, P Elliott, A B Mehta, D A Hughes
BACKGROUND: Fabry disease (FD) results from X-linked inheritance of a mutation in the GLA gene, encoding for alpha galactosidase A, and is characterized by heterogeneous clinical manifestations. Two phenotypes have been described "Classic" and "late onset" which cannot be predicted exclusively by genotype. The latter has been considered an attenuated form of the disease often affecting a single organ system commonly the heart. Recent studies have demonstrated that cardiac outcomes are similar in patients with classic and late onset mutations...
2018: PloS One
https://www.readbyqxmd.com/read/29617502/the-frequency-of-infective-endocarditis-in-candida-bloodstream-infections-a-retrospective-study-in-a-child-hospital
#16
Ahu Kara, İlker Devrim, Timur Meşe, Nuri Bayram, Murat Yılmazer, Gamze Gülfidan
INTRODUCTION: Fungal endocarditis is reported less frequently than bacterial endocarditis, with an incidence of 0-12% of the total pediatric infective endocarditis. OBJECTIVE: In this study, the incidence of infective endocarditis in Candida bloodstream infections in a tertiary hospital during the periods of 2007 and 2016 was reviewed. METHODS: Patients with positive blood or catheter cultures in terms of Candida spp. during the study period of January 2007 and January 2016 were analyzed in terms of Candida infective endocarditis...
January 2018: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29602932/-the-epidemiology-of-sudden-cardiac-arrest-in-prehospital-care-in-the-area-of-the-silesian-voivodeship
#17
Klaudiusz Nadolny, Joanna Gotlib, Mariusz Panczyk, Jerzy Robert Ładny, Zbigniew Białczak, Marcin Podgórski, Oksana Makar, Nataliya Izhytska, Robert Gałązkowski
OBJECTIVE: Introduction: Sudden cardiac arrest (SCA) is a serious medical and social issue. The incidence of SCA varies depending on the location and the circumstances. The aim: A retrospective analysis of non-hospital SCA cases from an epidemiological perspective. The research involved the population monitored by the Voivodeship Rescue Service (VRS) in Katowice. PATIENTS AND METHODS: Material and methods The analysis covered dispatch order forms and emergency medical procedure forms of the VRS in Katowice in 2016 (n = 249 872)...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29588140/cochlear-implant-function-in-a-patient-with-jervell-and-lange-nielsen-syndrome-after-defibrillation-by-countershock
#18
Shinsuke Kaneshiro, Harukazu Hiraumi, Kirito Shimamoto, Kaori Sasamori, Yumiko Kobayashi, Hiroaki Sato
Jervell and Lange-Nielsen syndrome (JLNS), a rare autosomal recessive congenital QT prolongation syndrome, is characterized by cardiac arrhythmias, syncopal episodes, and profound deafness. A cochlear implant (CI) for patients with JLNS is expected to result in hearing improvement. Sometimes, defibrillation is required if a patient experiences lethal arrhythmia. In this paper, we report a pediatric patient with JLNS who received defibrillation after CI surgery in his right ear at the age of 2 years. With intensive care, the post-operative course was uneventful, and the patient acquired satisfactory speech and hearing abilities...
March 24, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29581711/dual-versus-single-antiplatelet-therapy-for-patients-with-long-term-oral-anticoagulation-undergoing-coronary-intervention-a-systematic-review-and-meta-analysis
#19
Jing-Jing Yu, Chan Zou, Wen-Yu Liu, Guo-Ping Yang
Objective: The main aim of this meta-analysis is to compare the efficacy and safety of dual versus single antiplatelet therapy for patients taking oral anticoagulation (OAC) after coronary intervention. Background: The optimal regimen remains controversial for patients taking OAC after coronary intervention. Methods: PubMed, Embase and Cochrane Central Register of Controlled Trials were searched for eligible studies including data of triple therapy (TT) versus OAC plus single antiplatelet therapy for patients requiring OAC after coronary intervention...
December 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29579200/mechanical-dyssynchrony-of-the-left-atrium-during-sinus-rhythm-is-associated-with-history-of-stroke-in-patients-with-atrial-fibrillation
#20
Luisa Ciuffo, Yuko Y Inoue, Susumu Tao, Esra Gucuk Ipek, Muhammad Balouch, Joao A C Lima, Saman Nazarian, David D Spragg, Joseph E Marine, Ronald D Berger, Hugh Calkins, Hiroshi Ashikaga
Aims: We sought to evaluate the relationship between left atrial (LA) mechanical dyssynchrony and history of stroke or transient ischaemic attack (TIA) in patients with atrial fibrillation (AF). We hypothesized that mechanical dyssynchrony of the LA is associated with history of stroke/TIA independent of LA function and Cardiac failure, Hypertension, Age, Diabetes, Stroke/transient ischaemic attack (TIA), VAscular disease, and Sex category (CHA2DS2-VASc) score in patients with AF. Methods and results: We conducted a cross-sectional study of 246 patients with a history of AF (59 ± 10 years, 29% female, 26% non-paroxysmal AF) referred for catheter ablation to treat drug-refractory AF who underwent preablation cardiac magnetic resonance (CMR) in sinus rhythm...
April 1, 2018: European Heart Journal Cardiovascular Imaging
keyword
keyword
98554
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"