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https://www.readbyqxmd.com/read/27928866/semi-automatic-software-based-detection-of-atrial-fibrillation-in-acute-ischaemic-stroke-and-transient-ischaemic-attack
#1
M N Nickelsen, A Snoer, A M Ali, T Wienecke
BACKGROUND AND PURPOSE: Paroxysmal atrial fibrillation (PAF) is often asymptomatic and increases the risk of ischaemic stroke. Detection of PAF is challenging but crucial because a change of treatment decreases the risk of ischaemic stroke. Post-stroke investigations recommend at least 24-h continuous cardiac rhythm monitoring. Extended monitoring detects more PAF but is limited by costs due to manual analysis. Interpretive software might be a reasonable screening tool. The aim was to validate the performance and utility of Pathfinder SL software compared to manual analysis...
December 7, 2016: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27928263/a-36-year-old-woman-with-coronary-artery-dissection-two-weeks-after-abortion
#2
Arsalan Salari, Mahboobe Gholipur, Maedeh Rezaeidanesh, Anoosh Barzigar, Shahram Rahmani, Mohadeseh Pursadeghi, Hannan Ebrahimi
Spontaneous coronary artery dissection is a rare cause of acute coronary syndrome and sudden cardiac death. We report coronary artery dissection in a 36-year-old woman with retrosternal chest pain 2 weeks after abortion. Electrocardiography showed ST elevation in leads V2-V4 and ST depression in the inferior leads. Lab data were normal. Cardiac catheterization showed a suspicious thrombotic lesion at the proximal portion of the left anterior descending artery with a smooth contour consistent with distal haziness and dissection site...
April 13, 2016: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/27928262/non-hodgkin-s-lymphoma-presenting-as-constrictive-pericarditis-a-rare-case-report
#3
Maryam Nabati, Keyvan Yosofnezhad, Morteza Taghavi, Ali Abbasi, Ali Ghaemian
Constrictive pericarditis (CP) is an uncommon post inflammatory disorder. It is described as pericardial thickening, myocardial constriction, and impaired diastolic filling. The most common etiologies are idiopathy, mediastinal radiotherapy, and prior cardiac surgery. Less common etiologies include viral infections, collagen vascular disorders, renal failure, sarcoidosis, tuberculosis, and blunt chest trauma. CP can less commonly be caused by malignancy. We report a very rare case of non-Hodgkin's lymphoma (NHL) presenting twice with attacks of decompensated heart failure...
April 13, 2016: Journal of Tehran Heart Center
https://www.readbyqxmd.com/read/27927817/perioperative-management-of-adult-patients-with-a-history-of-stroke-or-transient-ischaemic-attack-undergoing-elective-non-cardiac-surgery
#4
Zehra Mehdi, Jonathan Birns, Judith Partridge, Ajay Bhalla, Jugdeep Dhesi
It is increasingly common for physicians and anaesthetists to be asked for advice in the medical management of surgical patients who have an incidental history of stroke or transient ischaemic attack (TIA). Advising clinicians requires an understanding of the common predictors, outcomes and management of perioperative stroke. The most important predictor of perioperative stroke is a previous history of stroke, and outcomes associated with such an event are extremely poor. The perioperative management of this patient group needs careful consideration to minimise the thrombotic risk and a comprehensive, individualised approach is crucial...
December 2016: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/27923487/reimplantation-of-the-aortic-valve-at-20%C3%A2-years
#5
Tirone E David, Carolyn M David, Christopher M Feindel, Cedric Manlhiot
OBJECTIVE: To provide additional information on clinical and echocardiographic outcomes after reimplantation of the aortic valve (RAV) in patients with aortic root aneurysm. METHODS: All 333 patients who underwent RAV at our hospital between 1989 and 2012 were followed prospectively with periodical clinical assessment and echocardiography. The mean duration of clinical follow-up was 10.3 ± 6.8 years, and follow-up was completed within 2 years before this report...
November 16, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27920591/left-atrial-myxomectomy-with-intraoperative-severe-mitral-regurgitation-and-complicated-postoperative-course-case-report
#6
Nareg Minaskeian, Patrick P Hu
Primary cardiac tumors are a rare occurrence with myxomas accounting for about half of the benign tumors. Once diagnosed, surgical resection is the standard of care. Our case describes a female in her 50s who underwent a myxoma resection under cardiopulmonary bypass via biatrial approach. Intraoperatively, the thin septal crux between the wall of the aorta and mitral valve was damaged during resection, requiring stem cell tissue matrix for repair. The patient also developed severe mitral regurgitation suggesting infarct to the left coronary system during resection, subsequently receiving a mechanical mitral valve and a saphenous vein bypass graft...
2016: Clinical Medicine Insights. Case Reports
https://www.readbyqxmd.com/read/27890882/a-case-of-brugada-syndrome-which-developed-status-epilepticus
#7
Misa Matsui, Kimiko Inoue, Harutoshi Fujimura, Saburo Sakoda
A 35-year-old man showed a convulsive attack with consciousness loss and was suspected of having Brugada syndrome 6 months prior to admission to our hospital. At the initial examination, the patient showed conjugate deviation, followed by left limb convulsions and consciousness loss. He regained consciousness after 1 minute, though cardiac arrest from ventricular fibrillation was noted during an electroencephalography (EEG) examination. Sinus rhythm recovered with defibrillation, though the convulsions persisted and a Status Epilepticus developed...
November 25, 2016: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/27881568/incident-type-2-myocardial-infarction-in-a-cohort-of-patients-undergoing-coronary-or-peripheral-arterial-angiography
#8
Hanna K Gaggin, Yuyin Liu, Asya Lyass, Roland R van Kimmenade, Shweta R Motiwala, Noreen Kelly, Aditi Mallick, Parul U Gandhi, Nasrien E Ibrahim, Mandy Simon, Anju Bhardwaj, Arianna Belcher, Jamie E Harisiades, Joseph M Massaro, Ralph B D'Agostino, James L Januzzi
BACKGROUND: -Despite growing recognition of Type 2 myocardial infarction (T2MI; related to supply-demand mismatch), little is known about its risk factors or its association with outcome. METHODS: -A single center cohort of patients undergoing coronary or peripheral angiography with or without intervention was prospectively enrolled and followed for incident type 1 and T2MI, as well as major adverse cardiovascular events (MACE, a composite of all-cause death, non-fatal MI, heart failure, stroke, transient ischemic attack, peripheral arterial complication and cardiac arrhythmia)...
November 21, 2016: Circulation
https://www.readbyqxmd.com/read/27879304/aortic-valve-fibroelastoma-a-rare-cause-of-stroke
#9
Vivek Kumar, Parita Soni, Arsalan Hashmi, Manfred Moskovits
The prevalence of primary cardiac tumours varies from 0.02% to 0.45%. Cardiac papillary fibroelastoma (CPF) is a rare tumour diagnosed incidentally on imaging. The clinical manifestations result from thromboembolisation and include transient ischaemic attack, stroke and sudden cardiac death. We present a patient aged 57 years with CPF arising from the aortic valve. The patient presented with right hemiparesis due to acute stroke. He received tissue plasminogen activator with complete resolution of neurological symptoms...
November 22, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27865959/ultrasensitive-cardiac-troponin-i-antibody-based-nanohybrid-sensor-for-rapid-detection-of-human-heart-attack
#10
Deepika Bhatnagar, Inderpreet Kaur, Ashok Kumar
An ultrasensitive cardiac troponin I antibody conjugated with graphene quantum dots (GQD) and polyamidoamine (PAMAM) nanohybrid modified gold electrode based sensor was developed for the rapid detection of heart attack (myocardial infarction) in human. Screen printed gold (Au) electrode was decorated with 4-aminothiophenol for amine functionalization of the Au surface. These amino groups were further coupled with carboxyl functionalities of GQD with EDC-NHS reaction. In order to enhance the sensitivity of the sensor, PAMAM dendrimer was successively embedded on GQD through carbodiimide coupling to provide ultra-high surface area for antibody immobilization...
November 16, 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27864105/epigallocatechin-3-gallate-prevents-cardiac-apoptosis-by-modulating-the-intrinsic-apoptotic-pathway-in-isoproterenol-induced-myocardial-infarction
#11
Azza I Othman, Magda M Elkomy, M A El-Missiry, Mohammed Dardor
(-)Epigallocatechin-gallate (EGCG) is an emerging natural therapy. This study examined the cardioprotective effect of EGCG on isoproterenol-induced myocardial damage and apoptosis and EGCG's role in modulating the expression of apoptotic signaling proteins. Experimental myocardial infarction was induced in albino Westar rats by isoproterenol (ISO) administration (100mg/kg, s.c.) at an interval of 24h on the 6th and 7th day. EGCG (15mg/kg, i.p.) was administered seven days before ISO. EGCG pretreatment significantly showed an anti-lipidemic effect and protected the cell membrane integrity, as shown by the blocking of changes in serum levels of CK-MB, LDH, ALP, ALT and troponin T...
November 15, 2016: European Journal of Pharmacology
https://www.readbyqxmd.com/read/27855640/long-term-secondary-prevention-of-acute-myocardial-infarction-sepat-guidelines-adherence-and-outcome
#12
Constantinos Ergatoudes, Erik Thunström, Annika Rosengren, Lena Björck, Kristina Bengtsson Boström, Kristin Falk, Michael Fu
BACKGROUND: A number of registry studies have reported suboptimal adherence to guidelines for cardiovascular prevention during the first year after acute myocardial infarction (AMI). However, only a few studies have addressed long-term secondary prevention after AMI. This study evaluates prevention guideline adherence and outcome of guideline-directed secondary prevention in patients surviving 2 years after AMI. METHODS: Patients aged 18-85 years at the time of their index AMI were consecutively identified from hospital discharge records between July 2010 and December 2011 in Gothenburg, Sweden...
November 17, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27835692/uric-acid-as-a-marker-of-mortality-and-morbidity-in-fabry-disease
#13
Daniel Rob, Josef Marek, Gabriela Dostálová, Lubor Goláň, Aleš Linhart
BACKGROUND: Serum uric acid (UA) elevation is common in patients with cardiovascular, renal and metabolic diseases. However, no study to date has analysed the role of UA in Fabry disease (FD). OBJECTIVES: To evaluate the association between serum UA levels and mortality and morbidity in FD. MATERIALS AND METHODS: We conducted a post-hoc analysis of a prospectively followed-up cohort of 124 patients with genetically proven FD. Serum UA levels were acquired at baseline; clinical events and mortality were assessed during regular visits every 6 to 12 months...
2016: PloS One
https://www.readbyqxmd.com/read/27825334/traditional-chinese-medicine-danlou-tablets-alleviate-adverse-left-ventricular-remodeling-after-myocardial-infarction-results-of-a-double-blind-randomized-placebo-controlled-pilot-study
#14
Shuai Mao, Lei Wang, Wenwei Ouyang, Yuanshen Zhou, Jianyong Qi, Liheng Guo, Minzhou Zhang, Aleksander Hinek
BACKGROUND: Danlou tablets, a patented Chinese Medicine, have been long approved for the treatment of ischemic heart disease in China. While numerous empirical observations suggested Danlou tablets could decrease frequency and duration of angina pectoris attacks, evidence supporting its efficacy on cardiac remodeling remains inadequate. Therefore, this pilot trial was designed to determine whether Danlou tablets would reduce adverse left ventricular (LV) remodeling in patients with myocardial infarction (MI)...
November 8, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27818233/systems-biology-dissection-of-mechanisms-and-chemical-basis-of-herbal-formula-in-treating-chronic-myocardial-ischemia
#15
Shuzhen Guo, Peng Li, Bangze Fu, Wenjing Chuo, Kuo Gao, Wuxia Zhang, Junyao Wang, Jianxin Chen, Wei Wang
Herbal medicine is a mixture of multiple compounds, and is intended to exhibit therapeutic effects by attacking multiple disease-causing modules simultaneously. However, it is still a challenge for scientists to untangle the complex biological mechanisms and underlying material basis of herbal medicine. Here, this study was designed to build a systems-biology platform for exploring the molecular mechanisms and corresponding active compounds, with a typical example applied to an herbal formula Qishenkel (QSKL) in the treatment of chronic myocardial ischemia...
November 3, 2016: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/27816321/safety-and-efficacy-of-contemporary-catheter-ablation-for-atrial-fibrillation-patients-with-a-history-of-cardioembolic-stroke-in-the-era-of-direct-oral-anticoagulants
#16
Kimitaka Nishizaki, Taihei Itoh, Masaomi Kimura, Yuichi Tsushima, Yoshihiro Shoji, Takahiko Kinjo, Yuji Ishida, Kenichi Sasaki, Daisuke Horiuchi, Shingo Sasaki, Hirofumi Tomita, Ken Okumura
BACKGROUND: The safety and efficacy of the contemporary atrial fibrillation (AF) ablation in patients with a recent or previous history of cardioembolic stroke (CS) or transient ischemic attack (TIA) remain to be established. METHODS: A total of 447 patients who underwent first-ever contact force (CF)-guided AF ablation with circumferential pulmonary vein isolation were included. Of these, 17 had CS or TIA within 6 months before ablation (Group 1), 30 more than 6 months before ablation (Group 2), and the other 400 without CS or TIA (Group 3)...
November 2, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/27813265/association-of-stroke-risk-biomarkers-with-stroke-symptoms-the-reasons-for-geographic-and-racial-differences-in-stroke-cohort
#17
K K Landry, K S Alexander, N A Zakai, S E Judd, D O Kleindorfer, V J Howard, G Howard, M Cushman
BACKGROUND: History of stroke symptoms in the absence of prior diagnosed stroke or transient ischemic attack (TIA) is associated with future stroke risk, as are biomarkers of inflammation, cardiac function and hemostasis. OBJECTIVE: To better elucidate pathobiology of stroke symptoms, we studied associations of these biomarkers with history of stroke symptoms. METHODS: The REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort enrolled 30,239 black and white Americans age 45 and older in 2003-7...
November 4, 2016: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/27803018/possible-complication-of-bee-stings-and-a-review-of-the-cardiac-effects-of-bee-stings
#18
Prabha Nini Gupta, B Krishna Kumar, Praveen Velappan, M D Sudheer
We report the case of a patient who, ∼3 weeks after multiple bee stings, developed a prolonged heart block, syncope and cardiac arrest. This required a temporary pacemaker to be implanted, which was later replaced with a permanent pacemaker. An ECG taken following surgery for a fractured humerus 6 years earlier was reportedly normal. The patient had been a rubber tapper who walked ∼1.5 km/day, but after the bee attack he was no longer able to walk or get up from the bed without experiencing syncope...
November 1, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27800191/successful-left-atrial-appendage-occlusion-with-the-new-generation-amulet%C3%A2-device-after-late-occurring-embolization-of-an-amplatzer%C3%A2-cardiac-plug-in-a-patient-with-repetitive-strokes
#19
Marco R Schroeter, Wolfgang Schillinger
The Amplatzer Cardiac Plug (ACP) is one of the most commonly used devices for percutaneous left atrial appendage (LAA) closure in order to prevent a stroke in patients with atrial fibrillation and contraindication for long-term oral anticoagulation therapy. We have previously described a patient who had experienced an embolization of the ACP device about 12 months after implantation and the device could be percutaneously retrieved. A few years later, he suffered from a posterior stroke and a stroke located in the brainstem as well as a transischemic attack (TIA)...
2016: Case Reports in Cardiology
https://www.readbyqxmd.com/read/27754283/me-04-1-assessment-of-central-blood-pressure-for-clinical-application
#20
Trefor Morgan
Central Systolic Blood Pressure is lower than brachial artery blood Pressure due to reflected waves and greater augmentation at the periphery. The relationship is not consistent during life and alters with aging of the blood vessels. Increasing stiffness means that a greater component of the reflected waves returns to the central aorta during systolic contraction causing more amplification and a higher systolic blood pressure. Diastolic blood pressure on the other hand is always higher in the aorta than at the periphery allowing blood flow...
September 2016: Journal of Hypertension
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