keyword
MENU ▼
Read by QxMD icon Read
search

chiva

keyword
https://www.readbyqxmd.com/read/28215465/the-frailty-syndrome-is-associated-with-adverse-health-outcomes-in-very-old-patients-with-stable-heart-failure-a-prospective-study-in-six-spanish-hospitals
#1
Carlos Rodríguez-Pascual, Emilio Paredes-Galán, Ana-Isabel Ferrero-Martínez, Jose-Luis Gonzalez-Guerrero, Mercedes Hornillos-Calvo, Rocio Menendez-Colino, Ivett Torres-Torres, Arturo Vilches-Moraga, Maria-Concepcion Galán, Francisco Suarez-Garcia, Maria-Teresa Olcoz-Chiva, Fernando Rodríguez-Artalejo
BACKGROUND: Most studies on the association between the frailty syndrome and adverse health outcomes in patients with heart failure (HF) have used non-standard definitions of frailty. This study examined the association of frailty, diagnosed by well-accepted criteria, with mortality, readmission and functional decline in very old ambulatory patients with HF. METHODS: Prospective study with 497 patients in six Spanish hospitals and followed up during one year. Mean (SD) age was 85...
February 8, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28207887/platelet-monocyte-derived-and-tissue-factor-carrying-circulating-microparticles-are-related-to-acute-myocardial-infarction-severity
#2
Gemma Chiva-Blanch, Kristian Laake, Peder Myhre, Vibeke Bratseth, Harald Arnesen, Svein Solheim, Lina Badimon, Ingebjørg Seljeflot
OBJECTIVE: Circulating microparticles (cMPs) are phospholipid-rich vesicles released from cells when activated or injured, and contribute to the formation of intracoronary thrombi. Tissue factor (TF, CD142) is the main trigger of fibrin formation and TF-carrying cMPs are considered one of the most procoagulant cMPs. Similar types of atherosclerotic lesions may lead to different types of AMI, although the mechanisms behind are unresolved. Therefore, we aimed to investigate the phenotype of cMPs found in plasma of ACS patients and its relation to AMI severity and thrombotic burden...
2017: PloS One
https://www.readbyqxmd.com/read/28114231/brief-report-about-the-role-of-hyperthermic-intraperitoneal-chemotherapy-in-a-prospective-randomized-phase-3-study-in-recurrent-ovarian-cancer-from-spiliotis-et-al
#3
Philipp Harter, Alexander Reuss, Jalid Sehouli, Luis Chiva, Andreas du Bois
A published so-called phase 3 study regarding HIPEC in ovarian cancer raised multiple questions. This commentary focusses on the weakness of the publication and discusses this in detail.
February 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28102078/peptide-selection-for-targeted-protein-quantitation
#4
Cristina Chiva, Eduard Sabidó
Targeted proteomics methods in their different flavors rely on the use of a few peptides as proxies for protein quantitation, which need to be specified either prior to or after data acquisition. However, in contrast with discovery methods that use all identified peptides for a given protein to estimate its abundance, targeted proteomics methods are limited in the number of peptides that are used for protein quantitation. Because only a few peptides per protein are acquired or extracted in targeted experiments, the selection of peptides that are used for targeted protein quantitation becomes crucial...
January 30, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28068186/bactericidal-efficacy-of-photodynamic-therapy-and-chitosan-in-root-canals-experimentally-infected-with-enterococcus-faecalis-an-in-vitro-study
#5
Fabio Camacho-Alonso, Encarnación Julián-Belmonte, Fernando Chiva-García, Yolanda Martínez-Beneyto
OBJECTIVE: To evaluate the antibacterial efficacy of photodynamic therapy (PDT) and chitosan against Enterococcus faecalis and assess the possible enhancive effect of chitosan on the photosensitizer methylene blue in experimentally infected root canals of extracted human teeth in vitro. BACKGROUND DATA: E. faecalis is frequently found in persistent endodontic infections. In this context, the antimicrobial PDT or newer antibacterial alternatives such as chitosan could become modern alternatives to existing antibacterial treatment approaches...
January 9, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28068169/value-of-neoadjuvant-chemotherapy-for-newly-diagnosed-advanced-ovarian-cancer-a-european-perspective
#6
Christina Fotopoulou, Jalid Sehouli, Giovanni Aletti, Philipp Harter, Sven Mahner, Denis Querleu, Luis Chiva, Hani Gabra, Nicoletta Colombo, Andreas du Bois
No abstract text is available yet for this article.
February 20, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27915085/monocyte-derived-circulating-microparticles-cd14-cd14-cd11b-and-cd14-cd142-are-related-to-long-term-prognosis-for-cardiovascular-mortality-in-stemi-patients
#7
Gemma Chiva-Blanch, Vibeke Bratseth, Vibeke Ritschel, Geir Ø Andersen, Sigrun Halvorsen, Jan Eritsland, Harald Arnesen, Lina Badimon, Ingebjørg Seljeflot
BACKGROUND: Circulating microparticles (cMPs) have been proposed as novel biomarkers of cardiovascular disease (CVD). We aimed to investigate the prognostic relevance of cMPs for future major adverse cardiovascular events (MACE) in STEMI patients. METHODS: We included 200 STEMI patients treated with percutaneous coronary intervention (PCI). One hundred patients with a primary composite end point (recurrent nonfatal acute MI, rehospitalization for heart failure, unscheduled PCI or death because of CV causes) were case-matched for sex, age, and CVD risk factors to 100 patients without a primary endpoint at the end of study follow-up (4...
January 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27903962/targeted-proteomics-in-urinary-extracellular-vesicles-identifies-biomarkers-for-diagnosis-and-prognosis-of-prostate-cancer
#8
Tamara Sequeiros, Marina Rigau, Cristina Chiva, Melania Montes, Iolanda Garcia-Grau, Marta Garcia, Sherley Diaz, Ana Celma, Irene Bijnsdorp, Alex Campos, Primiano Di Mauro, Salvador Borrós, Jaume Reventós, Andreas Doll, Rosanna Paciucci, Michiel Pegtel, Inés de Torres, Eduard Sabidó, Juan Morote, Mireia Olivan
Rapid and reliable diagnosis of prostate cancer (PCa) is highly desirable as current used methods lack specificity. In addition, identification of PCa biomarkers that can classify patients into high- and low-risk groups for disease progression at early stage will improve treatment decision-making. Here, we describe a set of protein-combination panels in urinary extracellular vesicles (EVs), defined by targeted proteomics and immunoblotting techniques that improve early non-invasive detection and stratification of PCa patients...
November 26, 2016: Oncotarget
https://www.readbyqxmd.com/read/27761508/dataset-of-the-botrytis-cinerea-phosphoproteome-induced-by-different-plant-based-elicitors
#9
Eva Liñeiro, Cristina Chiva, Jesús M Cantoral, Eduard Sabido, Francisco Javier Fernández-Acero
Phosphorylation is one of the main post-translational modification (PTM) involved in signaling network in the ascomycete Botrytis cinerea, one of the most relevant phytopathogenic fungus. The data presented in this article provided a differential mass spectrometry-based analysis of the phosphoproteome of B. cinerea under two different phenotypical conditions induced by the use of two different elicitors: glucose and deproteinized Tomate Cell Walls (TCW). A total 1138 and 733 phosphoproteins were identified for glucose and TCW culture conditions respectively...
June 2016: Data in Brief
https://www.readbyqxmd.com/read/27648981/the-frailty-syndrome-and-mortality-among-very-old-patients-with-symptomatic-severe-aortic-stenosis-under-different-treatments
#10
Carlos Rodríguez-Pascual, Emilio Paredes-Galán, Ana Isabel Ferrero-Martínez, José Antonio Baz-Alonso, Darío Durán-Muñoz, Eva González-Babarro, Marcelo Sanmartín, Teresa Parajes, Ivett Torres-Torres, Miguel Piñón-Esteban, Francisco Calvo-Iglesias, Maria Teresa Olcoz-Chiva, Fernando Rodríguez-Artalejo
BACKGROUND: The role of frailty as a prognostic factor in non-selected patients with symptomatic severe aortic stenosis (SAS) is still uncertain. This study aims to examine the association between the frailty syndrome and mortality among very old patients with symptomatic SAS, and to assess whether the association varies with the type of SAS treatment. METHODS AND RESULTS: Prospective study of 606 patients aged ≥75years with symptomatic SAS, recruited from February 2010 to January 2015, who were followed up through June 2015...
December 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27648648/european-society-of-gynaecologic-oncology-quality-indicators-for-advanced-ovarian-cancer-surgery
#11
Denis Querleu, François Planchamp, Luis Chiva, Christina Fotopoulou, Desmond Barton, David Cibula, Giovanni Aletti, Silvestro Carinelli, Carien Creutzberg, Ben Davidson, Philip Harter, Lene Lundvall, Christian Marth, Philippe Morice, Arash Rafii, Isabelle Ray-Coquard, Andrea Rockall, Cristiana Sessa, Ate van der Zee, Ignace Vergote, Andreas du Bois
OBJECTIVES: The surgical management of advanced ovarian cancer involves complex surgery. Implementation of a quality management program has a major impact on survival. The goal of this work was to develop a list of quality indicators (QIs) for advanced ovarian cancer surgery that can be used to audit and improve the clinical practice. This task has been carried out under the auspices of the European Society of Gynaecologic Oncology (ESGO). METHODS: Quality indicators were based on scientific evidence and/or expert consensus...
September 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27586201/genetic-analysis-of-uterine-aspirates-improves-the-diagnostic-value-and-captures-the-intra-tumor-heterogeneity-of-endometrial-cancers
#12
Alba Mota, Eva Colás, Pablo García-Sanz, Irene Campoy, Alejandro Rojo-Sebastián, Sonia Gatius, Ángel García, Luis Chiva, Sonsoles Alonso, Antonio Gil-Moreno, Xavier González-Tallada, Berta Díaz-Feijoo, August Vidal, Patrycja Ziober-Malinowska, Marcin Bobiński, Rafael López-López, Miguel Abal, Jaume Reventós, Xavier Matias-Guiu, Gema Moreno-Bueno
Endometrial cancer is the most common cancer of the female genital tract in developed countries. Although the majority of endometrial cancers are diagnosed at early stages and the 5-year overall survival is around 80%, early detection of these tumors is crucial to improve the survival of patients given that the advanced tumors are associated with a poor outcome. Furthermore, correct assessment of the pre-clinical diagnosis is decisive to guide the surgical treatment and management of the patient. In this sense, the potential of targeted genetic sequencing of uterine aspirates has been assessed as a pre-operative tool to obtain reliable information regarding the mutational profile of a given tumor, even in samples that are not histologically classifiable...
January 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/27580034/rapid-emergence-of-life-shown-by-discovery-of-3-700-million-year-old-microbial-structures
#13
Allen P Nutman, Vickie C Bennett, Clark R L Friend, Martin J Van Kranendonk, Allan R Chivas
Biological activity is a major factor in Earth's chemical cycles, including facilitating CO2 sequestration and providing climate feedbacks. Thus a key question in Earth's evolution is when did life arise and impact hydrosphere-atmosphere-lithosphere chemical cycles? Until now, evidence for the oldest life on Earth focused on debated stable isotopic signatures of 3,800-3,700 million year (Myr)-old metamorphosed sedimentary rocks and minerals from the Isua supracrustal belt (ISB), southwest Greenland. Here we report evidence for ancient life from a newly exposed outcrop of 3,700-Myr-old metacarbonate rocks in the ISB that contain 1-4-cm-high stromatolites-macroscopically layered structures produced by microbial communities...
September 22, 2016: Nature
https://www.readbyqxmd.com/read/27548786/hydration-status-executive-function-and-response-to-orthostatism-following-a-118-km-mountain-race-%C3%A2-are-they-interrelated
#14
I Martínez-Navarro, O Chiva-Bartoll, B Hernando, E Collado, V Porcar, C Hernando
PURPOSE: The present study aimed to explore whether Blood Pressure (BP) and Heart Rate Variability (HRV) responsiveness to orthostatism, jointly with Executive Function (EF) performance, were diminished following an ultraendurance mountain race. Besides, we wanted to assess whether hydration status was related to either performance or the abovementioned alterations. METHODS: Fifty recreational ultraendurance athletes participating in the Penyagolosa Trails CSP115 race (118 km and a total positive elevation of 5439 m) were evaluated before and after the competition...
August 18, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27519666/molecularly-imprinted-microparticles-in-lipid-based-formulations-for-sustained-release-of-donepezil
#15
André Luís Morais Ruela, Eduardo Costa de Figueiredo, Magali Benjamim de Araújo, Flávia Chiva Carvalho, Gislaine Ribeiro Pereira
Donepezil is a drug administered for Alzheimer's disease treatment, and it is a potential template molecule for imprinted microparticles. The precipitation polymerization technique allows the synthesis of spherical imprinted microparticles, and the intermolecular interactions among drug and molecularly imprinted polymers (MIPs) play a promising role for delineating drug delivery systems. Once that donepezil is a poorly-water soluble compound, lipid based-formulations (LBFs) may enhance its oral administration...
October 10, 2016: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27335253/figo-stage-iv-epithelial-ovarian-fallopian-tube-and-peritoneal-cancer-revisited
#16
REVIEW
Beyhan Ataseven, Luis M Chiva, Philipp Harter, Antonio Gonzalez-Martin, Andreas du Bois
Epithelial ovarian, fallopian tube and peritoneal cancer (EOC) is the seventh most common cancer diagnosis among women worldwide and shows the highest mortality rate of all gynecologic tumors. Different histological and anatomic spread patterns as well as multiple gene-expression based studies have demonstrated that EOC is indeed a heterogeneous disease. The prognostic factors that best predict the survival in this disease include: age, performance status and patient's comorbidities at the time of diagnosis; tumor biology, histological type, amount of residual tumor after surgery and finally tumor stage as surrogate for pre-operative tumor burden and growth pattern...
September 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27329576/modifications-of-fungal-membrane-proteins-profile-under-pathogenicity-induction-a-proteomic-analysis-of-botrytis-cinerea-membranome
#17
Eva Liñeiro, Cristina Chiva, Jesús M Cantoral, Eduard Sabidó, Francisco Javier Fernández-Acero
Botrytis cinerea is a model fungus for the study of phytopathogenicity that exhibits a wide arsenal of tools to infect plant tissues. Most of these factors are related to signal transduction cascades, in which membrane proteins play a key role as a bridge between environment and intracellular molecular processes. This work describes the first description of the membranome of Botrytis under different pathogenicity conditions induced by different plant-based elicitors: glucose and tomato cell wall (TCW). A discovery proteomics analysis of membrane proteins was carried out by mass spectrometry...
September 2016: Proteomics
https://www.readbyqxmd.com/read/27290332/incidence-of-medication-errors-in-a-surgical-intensive-care-unit-analisys-and-improvement-measures-implemented
#18
P Cuesta-Montero, E Domingo-Chiva, S Plata-Paniagua, J A Monsalve-Naharro, B Montalban-Moreno, J M Jimenez-Vizuete, A Valladolid-Walsh, R Peyro-García
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27290156/role-of-blood-cultures-during-continuous-renalreplacement-theraphy-in-septic-patients
#19
J A Monsalve-Naharro, P Cuesta-Montero, E Domingo-Chiva, S Plata-Paniagua, A López-Pérez, F Martinez-Lopez, J M Jimenez-Vizuete
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27283479/effect-of-a-high-fat-mediterranean-diet-on-bodyweight-and-waist-circumference-a-prespecified-secondary-outcomes-analysis-of-the-predimed-randomised-controlled-trial
#20
Ramon Estruch, Miguel Angel Martínez-González, Dolores Corella, Jordi Salas-Salvadó, Montserrat Fitó, Gemma Chiva-Blanch, Miquel Fiol, Enrique Gómez-Gracia, Fernando Arós, José Lapetra, Lluis Serra-Majem, Xavier Pintó, Pilar Buil-Cosiales, José V Sorlí, Miguel A Muñoz, Josep Basora-Gallisá, Rosa María Lamuela-Raventós, Mercè Serra-Mir, Emilio Ros
BACKGROUND: Because of the high density of fat, high-fat diets are perceived as likely to lead to increased bodyweight, hence health-care providers are reluctant to recommend them to overweight or obese individuals. We assessed the long-term effects of ad libitum, high-fat, high-vegetable-fat Mediterranean diets on bodyweight and waist circumference in older people at risk of cardiovascular disease, most of whom were overweight or obese. METHODS: PREDIMED was a 5 year parallel-group, multicentre, randomised, controlled clinical trial done in primary care centres affiliated to 11 hospitals in Spain...
August 2016: Lancet Diabetes & Endocrinology
keyword
keyword
98539
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"