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Acute embolism pulmonary

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https://www.readbyqxmd.com/read/29926573/-acute-pulmonary-embolism-about-paradox-judgments-and-evidences
#1
A Ancion, R Lopez, V D'Orio, A Ghuysen, R Zandona
Pulmonary embolism (PE) is the third most common cardiovascular disease in industrialized countries. Multiple clinical presentations and non-specific symptoms lead to frequents misdiagnosis. Using and plan therapeutic and admission versus discharge strategies.
May 2018: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29926572/-lower-limb-venous-thrombosis-management-in-the-acute-phase
#2
M Sprynger
Venous thromboembolism is the third cardiovascular disease in Europe. The cornerstone of the treatment of deep vein thrombosis is anticoagulation. It aims at avoiding harmful complications : thrombosis extension and recurrence, pulmonary embolism and post-thrombotic syndrome. Due to low molecular weight heparins, and recently, to direct oral anticoagulants, most of the patients can get treatment as outpatients. Unfortunately, despite guideline publications, the management of these patients may be complicated in real life and not correspond to evidence-based medicine...
May 2018: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29920349/bail-out-intracranial-stenting-with-solitaire-ab-device-after-unsuccessfull-trombectomy-in-acute-ischemic-stroke-of-anterior-circulation
#3
Sergio Nappini, Nicola Limbucci, Giuseppe Leone, Andrea Rosi, Leonardo Renieri, Arturo Consoli, Antonio Laiso, Iacopo Valente, Francesco Rosella, Riccardo Rosati, Salvatore Mangiafico
BACKGROUND: Recent trials established the efficacy of mechanical stent-retriever thrombectomy for treatment of stroke patients with large vessel occlusion (LVO) in the anterior circulation. However, stent-retriever thrombectomy may not accomplish successful recanalization in all patients. The aim of this study is to report the role of bail-out permanent stenting after failure of mechanical thrombectomy. METHODS: Among 430 patients included in a prospectively maintained database, we analysed 325 cases of anterior circulation LVO...
June 16, 2018: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29916259/polymorphisms-c677t-and-a1298c-of-mthfr-gene-homocysteine-levels-and-prothrombotic-biomarkers-in-coronary-and-pulmonary-thromboembolic-disease
#4
Eulo Lupi-Herrera, María Elena Soto-López, Antonio de Jesús Lugo-Dimas, Marcela Elizabeth Núñez-Martínez, Ricardo Gamboa, Claudia Huesca-Gómez, Lilia Mercedes Sierra-Galán, Verónica Guarner-Lans
The activity of the enzyme methylenetetrahydrofolate reductase (MTHFR) determines homocysteine (Hcy) levels, and polymorphisms in its gene affect the activity of the enzyme. Changes in the enzyme's activity may lead to a higher susceptibility to develop arterial and venous thromboembolic disease. The aim was to analyze the relationship between the C677T and A1298C polymorphisms of MTHFR, Hcy levels, and prothrombotic biomarkers in pulmonary embolism (PE) and acute myocardial ischemia (AMI). Clinical files of patients with thromboembolic diseases having complete data and whose doctor had requested an assay to determine the polymorphisms of the MTHFR gene, Hcy levels, and prothrombotic biomarkers were studied to search for the correlation between mutations of the MTHFR gene and Hcy levels in the different diseases...
January 1, 2018: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/29915643/predictors-of-hospital-stay-in-normotensive-acute-pulmonary-embolism-a-retrospective-pilot-study
#5
Osama Mukhtar, Oday Alhafidh, Mazin Khalid, Jaspreet Kaler, Ebad Rahman, Binav Shrestha, Manal Bakhiet, Sumit Dahal, Bikash Bhattarai, Praveen Datar, Omar Abdulfattah, Vijay Gayam, Joseph Quist, Danilo Enriquez, Frances Schmidt
Introduction : The aim of our study is to determine the clinical, biochemical, and imaging factors that affect the duration of hospital stay in patients admitted with normotensive acute pulmonary embolism. Methods : This was a single-center retrospective study conducted in a community hospital in New York metropolitan area for patients admitted from October 2015 to October 2017. Results : A total of 79 patients were included, the mean age was 55.76 ( SD  = 17.33), 29 cases were males (37%) and 50 cases were females (63%)...
2018: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29914983/inhibition-of-the-cyclophilin-a-cd147-interaction-attenuates-right-ventricular-injury-and-dysfunction-after-acute-pulmonary-embolism-in-rats
#6
Guangdong Lu, Zhenyu Jia, Qingquan Zu, Jinxing Zhang, Linbo Zhao, Haibin Shi
Acute pulmonary embolism (APE)-induced inflammation contributes to cardiomyocyte injury and dysfunction in the right ventricle (RV) of the heart. The interactions of cyclophilin A with its ligand extracellular matrix metalloproteinase inducer (EMMPRIN or CD147) may be involved in this inflammatory process. To this end, here we induced APE by intravenous injections of microspheres in Sprague-Dawley rats. We found that after the APE, cyclophilin A, and CD147 levels increased synchronously in RV tissue following APE and peaked at 24 hours...
June 18, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29911017/free-floating-right-heart-thrombus-with-acute-massive-pulmonary-embolism-a-case-report-and-review-of-the-literature
#7
Fida Charif, Mohamad Jihad Mansour, Righab Hamdan, Claudette Najjar, Pierre Nassar, Mohamad Issa, Elie Chammas, Mohamad Saab
Free-floating right heart thrombus (RHT) is an extreme medical emergency in the context of acute massive pulmonary embolism (PE). Despite the advances in early diagnosis, the management is still very debatable due to lack of consensus. We reported the case of a 66-year-old male, with a history of moderate renal dysfunction and dilated cardiomyopathy, who presented to the emergency department for acute dyspnea. His angiographic magnetic resonance imaging revealed bilateral extensive PE. Transthoracic echocardiography showed RHT with moderate right ventricular dysfunction and pulmonary hypertension...
April 2018: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29909859/a-meta-analysis-of-outcomes-of-catheter-directed-thrombolysis-for-high-and-intermediate-risk-pulmonary-embolism
#8
REVIEW
Efthymios D Avgerinos, Zein Saadeddin, Adham N Abou Ali, Larry Fish, Catalin Toma, Maria Chaer, Belinda N Rivera-Lebron, Rabih A Chaer
OBJECTIVE: During the past few years, there has been a surge in the use of catheter-directed thrombolysis (CDT) for acute pulmonary embolism (PE), in the form of either standard CDT or ultrasound-assisted CDT (usCDT). This is a systematic review and meta-analysis of all published series on contemporary CDT for acute PE seeking to determine their clinical efficacy, stratifying by PE severity and CDT modality. METHODS: A comprehensive MEDLINE and Embase search was performed to identify studies that reported outcomes of CDT for acute PE published from 2009 to July 2017...
July 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29909851/may-thurner-syndrome-and-the-risk-of-pulmonary-embolism-in-patients-with-acute-deep-venous-thrombosis
#9
Song Jin, Ziqiang Sun, Xiaoqin Li, Tao Jian, Xing Jin, Sheng Li, Guodong Wang, Chong Ma, Kai Cui, Peng Xu
OBJECTIVE: Pulmonary embolism (PE) is the most common complication of deep venous thrombosis (DVT). May-Thurner syndrome (MTS) is known to increase the risk of DVT, but an association between MTS and PE has not been established. This study investigated an association between MTS and the risk of PE in patients with acute lower extremity DVT. METHODS: Between June 2014 and September 2016, there were 112 patients with DVT at our hospital who underwent venous angiography and computed tomography pulmonary angiography...
July 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29906426/importance-of-early-insertion-of-inferior-vena-cava-filters-in-unstable-patients-with-acute-pulmonary-embolism
#10
Paul D Stein, Fadi Matta, Frank R Lawrence, Mary J Hughes
BACKGROUND: Immortal time bias is a possible confounding factor in cohort studies. In this investigation, we assessed mortality with inferior vena cava (IVC) filters in unstable patients with pulmonary embolism using a design that eliminated immortal time bias. METHODS: Data are from Premier Healthcare Database, 2010-2014. International Classification of Disease-9th Clinical Modification codes were used. Unstable patients with pulmonary embolism and an admitting diagnosis of pulmonary embolism as well as a primary diagnosis of pulmonary embolism were included...
June 12, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29901460/mechanical-circulatory-devices-in-acute-heart-failure
#11
Marc Pineton de Chambrun, Nicolas Bréchot, Alain Combes
PURPOSE OF REVIEW: Temporary circulatory support (TCS) with short-term mechanical circulatory support (MCS) devices is increasingly used as a salvage therapy for patients with refractory cardiogenic shock. This article provides an overview of current devices, their indications and management, and discusses results of recent case series and trials. RECENT FINDINGS: Percutaneous active MCS devices (Impella, TandemHeart…) and venoarterial extracorporeal membrane oxygenation (VA-ECMO) are utilized as a bridge to 'decision' that includes weaning after cardiac function recovery, transplantation, long-term MCS and withdrawal in case of futility...
June 8, 2018: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/29898911/phlegmasia-cerulea-dolens-presenting-with-acute-compartment-syndrome-and-pulmonary-embolism
#12
Achintya Dinesh Singh, Nayani Makkar, Animesh Ray, Rita Sood
No abstract text is available yet for this article.
June 13, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29898910/fulminant-pulmonary-embolism-with-fatal-outcome-in-a-patient-with-low-clinical-prediction-scores
#13
Christian Degen, Severin Poechtrager, Gregor Leibundgut
We present a case of a 72-year-old man with submassive acute pulmonary thromboembolism. Pulmonary embolism severity index Score and common clinical risk stratification recommended systemic anticoagulation and a clinical course without complications was expected. A primary reperfusion strategy was not indicated by the current guidelines. Under established anticoagulation, the patient was found in cardiac arrest immediately after mobilisation from the bed the next morning. Right heart catheterisation under ongoing resuscitation revealed a complete obstruction of the right pulmonary artery by a big thrombus...
June 13, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29896249/the-effect-of-nitric-oxide-inhalation-on-heart-and-pulmonary-circulation-in-rabbits-with-acute-massive-pulmonary-embolism
#14
Zeming Zhang, Kun Pan, Lu Chen, Yancun Wang
The aim of the present study was to investigate the effect of nitric oxide inhalation (NOI) on cardiac troponin I (CTnI) levels and mean pulmonary arterial pressure (mPAP) in rabbits with acute massive pulmonary embolism (AMPE). Thirty rabbits were used as animal models for AMPE and received different treatments. A total of 4 h after successful modeling, the control group (CON, n=10) received conventional thrombolysis, whereas the treatment group (TRE, n=10) received conventional thrombolysis plus NOI. The experimental group (EXP, n=10) did not receive any treatments...
July 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29893185/early-thrombolytic-failure-in-a-patient-with-massive-pulmonary-embolism-combined-with-multiple-organ-dysfunction-syndrome-what-next
#15
Furong Liu, Song Yang, Weishuo Liu, Baiyun Tang, Wenbo Zhang, Cheng Zhang, Wenwei Liao, Anbin Hu
Carbon monoxide (CO) poisoning, the most frequent type of poisoning, alters hemodynamics and creates tissue hypoxia that ultimately leads to thromboembolism. We herein describe a previously healthy 17-year-old male patient who developed acute CO poisoning while bathing in the same room as a gas heater. He was first treated with urokinase thrombolytic therapy at a local hospital, which proved ineffective. The patient was admitted to our hospital with unstable circulation and was diagnosed with massive pulmonary embolism combined with multiple organ dysfunction syndrome...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29890567/red-cell-transfusion-and-clinical-outcomes-in-acute-pulmonary-embolism-harmful-therapy-or-an-indicator-of-sicker-patients-with-poor-prognosis
#16
EDITORIAL
Sanjeev D Chunilal, Erica M Wood
No abstract text is available yet for this article.
June 11, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29883039/reduction-in-physical-function-in-women-after-venous-thromboembolism
#17
Kaitlin A Hagan, Laura B Harrington, Jihye Kim, Oana Zeleznik, Eric B Rimm, Francine Grodstein, Christopher Kabrhel
BACKGROUND: Physical function is integral to healthy aging; however, limited research has examined the association of venous thromboembolism(VTE) with subsequent physical function. OBJECTIVES: To prospectively evaluate the relationship between VTE and decline in physical function among 80,836 women from the Nurses' Health Study(NHS), ages 46-72 in 1992, and 84,304 women from the Nurses' Health Study II(NHS II), ages 29-48 in 1993. METHODS: Physical function was measured by the Medical Outcomes Short Form-36 physical function scale, administered every four years...
June 8, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29875063/life-threatening-pulmonary-embolism-that-occurred-immediately-after-acute-carbon-monoxide-poisoning-in-the-emergency-department
#18
Seok Jeong Lee, Yong Sung Cha, Yoonsuk Lee, Hyun Kim
The risk of thromboembolism is higher in those with carbon monoxide (CO) poisoning than in the general population. Pulmonary embolisms (PE) usually develop during admission for acute CO poisoning. We report the first case of a life-threatening PE that occurred immediately after acute CO poisoning and was treated with a thrombolytic agent. A 38-year-old woman presented at the emergency department with a stuporous mental status immediately after acute CO poisoning. She was started on hyperbaric oxygen therapy (HBOT), which maintained her hemodynamic stability...
May 30, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29872249/percutaneous-pulmonary-embolism-thrombectomy-and-thrombolysis-technical-tips-and-tricks
#19
REVIEW
Zlatko Devcic, William T Kuo
Catheter-directed therapy (CDT) is now acknowledged as a treatment option for select patients with acute massive or submassive pulmonary embolism (PE), and more patients are being considered for CDT if there is available expertise. Therefore, interventionalists should be aware of the variety of catheter-based treatment options, specific pitfalls to avoid during therapy, and the appropriate treatment endpoints. This article reviews currently available techniques and protocols for treating acute massive and submassive PE, with tips to safely and successfully perform percutaneous PE interventions...
June 2018: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/29872248/catheter-directed-thrombolysis-for-submassive-pulmonary-embolism
#20
REVIEW
Matthew A Chiarello, Akhilesh K Sista
Acute pulmonary embolism (PE) is a leading cause of morbidity and mortality in the United States. PE associated with right ventricular strain, termed submassive or intermediate-risk PE, is associated with an increased rate of clinical deterioration and short-term mortality. Trials have demonstrated systemic thrombolytics may improve patient outcomes, but they carry a risk of major hemorrhage. Catheter-directed thrombolysis (CDT) may offer similar efficacy to and a lower risk of catastrophic hemorrhage than systemic thrombolysis...
June 2018: Seminars in Interventional Radiology
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