C G Geary, D Catovsky, E Wiltshaw, G R Milner, M C Scholes, S Van Noorden, L D Wadsworth, S Muldal, J E MacIver, D A Galton
The natural history and haematological features of 18 patients with a chronic form of myelomonocytic leukaemia are described. The majority were elderly and, in this series, females predominated. Haematological prodomata, such as unexplained monocytosis, leucopenia, or thrombocytopenia were common, and the clinical onset was insidious. Splenomegaly was variable but tended to increase as the disease progressed. Anaemia was usually less than in the acute disease, unless compounded by iron deficiency. The blood film typically showed a mixed monocytosis and granulocytosis, cells in both lines showing abnormalities...
July 1975: British Journal of Haematology