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Neonate with PROM

Gilles Kayem, Frederic Batteux, Noémie Girard, Thomas Schmitz, Marion Willaime, Francoise Maillard, Pierre Henri Jarreau, Francois Goffinet
OBJECTIVE: Examine the predictive value for maternal-fetal infection of routine bedside tests detecting the proinflammatory cytokines, TNFα and IL-6, in the vaginal secretions of women with premature rupture of the membranes (PROM). STUDY DESIGN: This prospective two-center cohort study included all women hospitalized for PROM over a 2-year period. A bedside test assessed IL-6 and TNFα in vaginal secretions. Both centers routinely tested CRP and leukocytes, assaying both in maternal serum, and analyzed vaginal bacterial flora; all samples were repeated twice weekly until delivery...
January 12, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Philippa Middleton, Emily Shepherd, Vicki Flenady, Rosemary D McBain, Caroline A Crowther
BACKGROUND: Prelabour rupture of membranes (PROM) at term is managed expectantly or by planned early birth. It is not clear if waiting for birth to occur spontaneously is better than intervening, e.g. by inducing labour. OBJECTIVES: The objective of this review is to assess the effects of planned early birth (immediate intervention or intervention within 24 hours) when compared with expectant management (no planned intervention within 24 hours) for women with term PROM on maternal, fetal and neonatal outcomes...
January 4, 2017: Cochrane Database of Systematic Reviews
Bethany Stetson, Judith U Hibbard, Isabelle Wilkins, Heidi Leftwich
OBJECTIVE: To examine the differences in perinatal outcomes among women with a prior preterm birth who received cerclage compared with cerclage plus 17α-hydroxyprogesterone caproate. METHODS: Women with transvaginal cerclage placement and a prior delivery between 16 and 36 weeks of gestation were identified over a 10-year period (July 2002 to May 2012) in this retrospective cohort study. Exclusion criteria were delivery at another institution, abdominal cerclage, multiple gestations, and major fetal anomalies...
November 2016: Obstetrics and Gynecology
G Vetter, A Knipprath, A Niklaus, N Kalberer, I Hösli
Introduction: It is estimated that after premature rupture of membranes (PROM) at term, 60% of all women go into labour within 48 h, 95% within 72 h. Often labour is induced after 24 h because the risk of maternal and neonatal infection rises. The majority of clinicians advise hospital care to allow monitoring and detection of problems. But for low-risk patients who meet strict inclusion criteria, sometimes home management is possible. This study examines the safety and costs of home management. Material and Methods: We included 239 patients with PROM at term, 202 of them with hospital and 37 with home management...
October 2016: Zeitschrift Für Geburtshilfe und Neonatologie
Nada Aracic, Ivica Stipic, Ivana Jakus Alujevic, Petar Poljak, Mario Stipic
AIM: To evaluate the influence of cervical length (CL) and parity as prediction factors for assessment of cesarean section (CS) risk in women with premature rupture of membranes (PROM) at term and unfavorable cervix, undergoing induction of labor (IOL) with dinoprostone intracervical gel. METHODS: A prospective study involved 50 nulliparous and 51 multiparous women admitted for IOL. Pre-induction CL was measured and delivery outcomes were recorded. RESULTS: Nulliparous women were younger than the multiparous (26...
January 1, 2017: Journal of Perinatal Medicine
Lynn M Yee, William A Grobman
OBJECTIVE: To investigate the relationship between fetal presentation at the time of admission for preterm premature rupture of membranes (PROM) and perinatal outcomes, including gestational latency, among women in a large and well-characterized population with preterm PROM at less than 32 weeks of gestation. METHODS: This was a secondary analysis of data from women randomized to receive magnesium sulfate compared with placebo in the previously reported Maternal-Fetal Medicine Units Network Beneficial Effects of Antenatal Magnesium Sulfate (1997-2004) trial...
October 2016: Obstetrics and Gynecology
Dana Sadeh-Mestechkin, Nivin Samara, Amir Wiser, Ofer Markovitch, Gil Shechter-Maor, Tal Biron-Shental
PURPOSE: To compare maternal and neonatal outcomes in induced vs. expectant management of term PROM. METHODS: This retrospective study included patients with term PROM. A total of 325 were enrolled: 213 managed expectantly and 112 induced at admission and matched according to gestational age. Expectant management group patients were allowed to defer labour induction up to 48 h. Primary outcome measures were maternal or foetal signs of infection (chorioamnionitis, early neonatal sepsis or postpartum endometritis) and prolonged maternal hospitalization...
November 2016: Archives of Gynecology and Obstetrics
Liran Hiersch, Eyal Krispin, Amir Aviram, Moran Mor-Shacham, Rinat Gabbay-Benziv, Yariv Yogev, Eran Ashwal
OBJECTIVE: To identify predictors for prolonged interval from premature rupture of membranes (PROM) to spontaneous onset of labor in women presenting with PROM and low Bishop score at term. METHODS: A retrospective study of women presenting with PROM and Bishop score < 7 at term (≥37weeks) in a tertiary hospital (2013-14). Spontaneous onset of labor was defined as presence of regular uterine contractions and Bishop score ≥ 7. Women with interval from PROM to spontaneous onset of labor of <24hours (short interval group) were compared to those with interval ≥ 24 hours (prolonged interval group)...
August 25, 2016: Journal of Maternal-fetal & Neonatal Medicine
Linda M McLaughlin, Glenn J Gardener
AIM: The aim of this study was to determine neonatal outcomes in pregnancies complicated by prelabour rupture of membranes (PROM) before 24 weeks' gestation. METHODS: We performed a retrospective review of medical records over a 5-year period (2007-2011) at Mater Health Services, South Brisbane, Australia. Data relating to the antenatal and perinatal course of pregnancies complicated by PROM before 24 weeks' gestation were collected. Data were also collected on neonatal diagnoses, management and outcomes for all liveborn infants resulting from these pregnancies...
July 2016: Journal of Paediatrics and Child Health
Shun-Yan Duan, Xiang-Yong Kong, Feng-Dan Xu, Hong-Yan Lv, Rong Ju, Zhan-Kui Li, Shu-Juan Zeng, Hui Wu, Xue-Feng Zhang, Wei-Peng Liu, Fang Liu, Hong-Bin Cheng, Yan-Jie Ding, Tie-Qiang Chen, Ping Xu, Li-Hong Yang, Su-Jing Wu, Jin Wang, Li Peng, Xiao-Lin Zhao, Hui-Xian Qiu, Wei-Xi Wen, Ying Li, Lan Li, Zheng Wen, Guo Guo, Feng Wang, Gai-Mei Li, Wei Li, Xiao-Ying Zhao, Yun-Bo Xu, Wen-Chao Chen, Huan Yin, Xiao-Liang Wang, Rui-Yan Shan, Mei-Ying Han, Chun-Yan Yang, Zhi-Chun Feng
OBJECTIVE: To investigate the effect of premature rupture of the membrane (PROM) on neonatal complications in premature infants. METHODS: The registration information of 7684 preterm infants with gestational age <37 weeks were collected from the cooperative units in the task group between January 1, 2014 to December 31, 2014. Specially trained personnel from each cooperative units filled in the unified form in a standardized format to record the gender, gestational age, birth weight, PROM, placental abruption, antenatal corticosteroid, Apgar score, amniotic fluid pollution, and complications of the infants...
June 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
Mia Kibel, Elizabeth Asztalos, Jon Barrett, Michael S Dunn, Carly Tward, Alex Pittini, Nir Melamed
OBJECTIVE: To assess the natural history and contemporary outcomes in pregnancies complicated by previable preterm premature rupture of membranes (PROM). METHODS: Retrospective study of all women with a singleton or twin pregnancy admitted to a single tertiary referral center who experienced preterm PROM between 20 and 23 6/7 weeks of gestation during 2004-2014 and underwent expectant management. Women electing termination of pregnancy and pregnancies complicated by major fetal anomalies were excluded...
August 2016: Obstetrics and Gynecology
Florentina Sava, Gergely Toldi, András Treszl, Júlia Hajdú, Ágnes Harmath, Tivadar Tulassay, Barna Vásárhelyi
BACKGROUND: Inappropriate activation of T lymphocytes plays an important role in perinatal complications. However, data on T lymphocyte activation markers of preterm infants is scarce. We investigated the association between gender, gestational and postnatal age, preeclampsia (PE), premature rupture of membranes (PROM) as well as prenatal steroid treatment (PS) and the frequency of activated T lymphocyte subsets (HLA-DR+, CD69+, CD25+, CD62L+) and major T lymphocyte subpopulations (CD4, CD8, Th1, Th2, naïve, memory) in peripheral blood during the first postnatal week in preterm infants...
2016: BMC Immunology
Tigist Endale, Netsanet Fentahun, Desta Gemada, Mamusha Aman Hussen
BACKGROUND: Premature rupture of membrane (PROM) is linked to significant maternal prenatal mortalities and morbidity. In Ethiopia, where maternal mortality is still high, the maternal and fetal outcomes in PROM is very important to decrease maternal and child mortality and for better management and prevention of complications. Thus, this study aimed to detect the maternal and fetal outcomes and associated factors in term PROM at Mizan-Aman General Hospital, south-west Ethiopia. METHODS: A retrospective cross sectional study was conducted using data available at Mizan-Aman General Hospital during a period of 3 years (January 2011 to December 2013)...
2016: World Journal of Emergency Medicine
Vlora Ademi Ibishi, Rozalinda Dusan Isjanovska
BACKGROUND: Pre-labour Rupture of Membranes (PROM) is an important cause of maternal and fetal morbidity and increased rate of cesarean section delivery. AIM: The aim of this study is to investigate the clinical characteristics, PROM-delivery interval, mode of delivery, and early maternal neonatal outcome among pregnant patients presenting with pre-labour rupture of membranes. MATERIAL AND METHODS: This prospective case control study is implemented at the Obstetric and Gynecology Clinic of the University Clinical Center of Kosovo...
June 15, 2015: Open Access Macedonian Journal of Medical Sciences
Menno van der Holst, C W P Gerco van der Wal, Ron Wolterbeek, Willem Pondaag, Thea P M Vliet Vlieland, Rob G H H Nelissen
OBJECTIVE: Irrespective of treatment history, shoulder dysfunction may occur in children with neonatal brachial plexus palsy. Following internal contracture release and/or muscle tendon transfer (ICR/MTT) shoulder function gain is possible. This study describes the outcomes of ICR/MTT for children with neonatal brachial plexus palsy, with or without prior nerve surgery (a group with prior nerve surgery and a group without prior nerve surgery). PATIENTS AND METHODS: The study included children who underwent an ICR/MTT with a minimum follow-up of 6 months...
July 18, 2016: Journal of Rehabilitation Medicine
Eran Ashwal, Eyal Krispin, Amir Aviram, Ella Aleyraz, Rinat Gabby-Benziv, Arnon Wiznitzer, Yariv Yogev, Liran Hiersch
PURPOSE: We aimed to evaluate perinatal outcome in women with prolonged (>24 h) premature rupture of membranes (PROM) undergoing induction of labor (IoL). METHODS: We retrospectively assessed all women presenting with term (≥37 weeks) PROM and Bishop-score <7 in a tertiary hospital (2012-14). Women without spontaneous onset of labor <24 h from PROM underwent Prostaglandin E2 (PGE2) IoL and were compared to women with low Bishop-score who developed spontaneous onset of labor <24 h...
November 2016: Archives of Gynecology and Obstetrics
Alemnesh H Mirkuzie, Mitike Molla Sisay, Mulu Muleta Bedane
BACKGROUND: The Public Health Centers (HCs) provide basic obstetric and neonatal care to about 80% of the eligible population in Addis Ababa. Hospitals provide comprehensive services and are referral centers for complications that cannot be managed at the HCs. This study assessed the proportion of obstetric referrals in general and referrals due to premature rupture of membranes (PROM) at term in particular, from the HCs in Addis Ababa and explored its appropriateness and management in hospitals...
January 25, 2016: BMC Research Notes
Zaskia M Rodriguez Gonzalez, Karla Leavitt, Jose Martin, Erika Benabe, Josefina Romaguera, Ivette Negrón
INTRODUCTION: Based on our population data, the teen pregnancy rate and the prevalence of sexually transmitted infections (STIs) reported during pregnancy are worrisome. STIs appear to pose a threat to pregnancy outcomes including preterm birth (PTB), neonatal low birth weight (NLBW) and premature rupture of membranes (PROM). The objective of this study is to determine the prevalence of STIs in pregnant teens and the association of this variable to adverse pregnancy outcomes. METHODS: We performed a cross sectional study to assess the prevalence of STIs among pregnant teens during a 4-year period at our institution...
July 2015: Boletín de la Asociación Médica de Puerto Rico
Ji Yeon Lee, Tae Gyu Ahn, Jong Kwan Jun
OBJECTIVE: To compare postnatal outcomes in pregnancies managed expectantly after previable preterm premature rupture of membranes (PROM) in relation to amniotic fluid volume. METHODS: A retrospective cohort study was performed in 92 women with amniotic fluid leakage for more than a week after previable preterm PROM (gestational age 14 1/7-24 0/7 weeks) who delivered a liveborn neonate at or after 24 1/7 weeks of gestation from 2002 to 2014. Short-term (sepsis, intracerebral hemorrhage, retinopathy of prematurity, respiratory distress syndrome, bronchopulmonary dysplasia) and long-term (cerebral palsy and developmental delay) outcomes were compared between women with (n=58) and without persistent oligohydramnios (n=34), defined as maximal vertical pocket less than 2 cm or amniotic fluid index less than 5 cm...
November 2015: Obstetrics and Gynecology
Sayuri Matsunami, Nobuyasu Komasawa, Yusuke Kusaka, Nozomi Majima, Toshiaki Minami
Here we report a case of severe septic shock immediately following cesarean section. A pregnant woman with dichorionic diamniotic twins was diagnosed with preterm rupture of membranes (PROM). Ritodrine hydrochloride and betamethasone did not sufficiently relieve abdominal extension; emergency cesarean section was scheduled 4 days later, at 31 week 5 day gestation. The patient did not show any symptoms or laboratory data suggesting infection. Spinal anesthesia was initiated with 2.2 ml of 0.5% bupivacaine hydrochloride and fentanyl 10 μg at L3-4; sensory loss (T3) was confirmed...
August 2015: Masui. the Japanese Journal of Anesthesiology
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