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https://www.readbyqxmd.com/read/28329118/comparison-of-surgical-approach-and-extent-of-resection-for-masaoka-koga-stage-i-and-ii-thymic-tumours-in-europe-north-america-and-asia-an-international-thymic-malignancy-interest-group-retrospective-database-analysis%C3%A2
#1
Wentao Fang, Xiaopan Yao, Alberto Antonicelli, Zhitao Gu, Frank Detterbeck, Eric Vallières, Ralph W Aye, Alexander S Farivar, James Huang, Yue Shang, Brian E Louie
OBJECTIVES: Surgeons at different institutions worldwide choose different types of operations for thymic tumours. It is not known whether these differences affect the outcomes of the patients. METHODS: A total of 1430 patients with Masaoka-Koga pathological Stage I-II thymic tumours without myasthenia gravis or pre-treatment were identified from the International Thymic Malignancy Interest Group retrospective database. Outcomes of patients from 3 major continents (Europe, North America and Asia) were compared...
February 28, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28303359/vitamin-d-deficiency-as-a-risk-factor-for-the-development-of-autoantibodies-in-patients-with-asia-and-silicone-breast-implants-a-cohort-study-and-review-of-the-literature
#2
Maartje J L Colaris, Rene R van der Hulst, Jan Willem Cohen Tervaert
The development of autoimmunity and/or autoimmune diseases is multifactorial. Vitamin D is one of the factors that might play a role. We postulated that both the presence of adjuvants and insufficient levels of vitamin D may result in the development of autoimmunity in patients with autoimmune/inflammatory syndrome induced by adjuvants (ASIA) in relation to silicone implant incompatibility. We measured vitamin D levels in 135 patients with ASIA in relation to silicone implant incompatibility and related findings to the presence of autoantibodies that are commonly used to diagnose systemic autoimmune diseases...
March 17, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28285868/more-than-meets-the-eye-klebsiella-pneumoniae-invasive-liver-abscess-syndrome-presenting-with-endophthalmitis
#3
Jan Van Keer, Karel Van Keer, Joachim Van Calster, Inge Derdelinckx
BACKGROUND: Endophthalmitis is a feared complication of pyogenic liver abscesses caused by hypervirulent Klebsiella pneumoniae strains. First described in East Asia in the 1980s, this invasive syndrome is only recently emerging in Europe and America. CASE REPORT: We describe an 84-year-old man who presented to the emergency department with fever, orbital cellulitis, and bilateral visual loss. Although the patient had no overt abdominal symptoms, computed tomography scan revealed a pyogenic liver abscess...
March 9, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28285789/zika-virus-history-epidemiology-transmission-and-clinical-presentation
#4
REVIEW
Byung-Hak Song, Sang-Im Yun, Michael Woolley, Young-Min Lee
Zika virus (ZIKV), a mosquito-borne positive-stranded RNA virus of the family Flaviviridae (genus Flavivirus), is now causing an unprecedented large-scale outbreak in the Americas. Historically, ZIKV spread eastward from equatorial Africa and Asia to the Pacific Islands during the late 2000s to early 2010s, invaded the Caribbean and Central and South America in 2015, and reached North America in 2016. Although ZIKV infection generally causes no symptoms or only a mild self-limiting illness, it has recently been linked to a rising number of severe neurological diseases, including microcephaly and Guillain-Barré syndrome...
March 3, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28276794/insufficient-efficacy-and-safety-of-intravenous-ribavirin-in-treatment-of-haemorrhagic-fever-with-renal-syndrome-caused-by-puumala-virus
#5
Oleg V Malinin, Alexander E Platonov
BACKGROUND: Intravenous ribavirin has been reported to be an effective treatment for haemorrhagic fever with renal syndrome (HFRS) caused by Hantaan virus in Asia. However, its therapeutic benefits for HFRS caused by Puumala virus (PUUV) in Europe are still unknown. METHODS: A randomized, open-label study of efficacy and safety of intravenous ribavirin in the treatment of HFRS was conducted in the European part of Russia. Seventy-three patients with suspected HFRS within 4 d of the onset of the disease were randomized to receive either intravenous ribavirin (33 mg/kg, followed by 16 mg/kg given every 6 h for 4 d and by 8 mg/kg given every 8 h for 3 d) plus standard therapy (n = 37) or standard therapy alone (n = 36)...
March 3, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28264526/%C3%AE-n-oxalyl-l-%C3%AE-%C3%AE-diaminopropionic-acid-%C3%AE-odap-content-in-lathyrus-sativus-the-integration-of-nitrogen-and-sulfur-metabolism-through-%C3%AE-cyanoalanine-synthase
#6
REVIEW
Quanle Xu, Fengjuan Liu, Peng Chen, Joseph M Jez, Hari B Krishnan
Grass pea (Lathyrus sativus L.) is an important legume crop grown mainly in South Asia and Sub-Saharan Africa. This underutilized legume can withstand harsh environmental conditions including drought and flooding. During drought-induced famines, this protein-rich legume serves as a food source for poor farmers when other crops fail under harsh environmental conditions; however, its use is limited because of the presence of an endogenous neurotoxic nonprotein amino acid β-N-oxalyl-l-α,β-diaminopropionic acid (β-ODAP)...
February 28, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28254106/development-of-acupuncture-and-moxibustion-protocol-in-a-clinical-trial-for-irritable-bowel-syndrome
#7
Joyce K Anastasi, Bernadette Capili, Michelle Chang
Traditional Chinese medicine encompasses many different practices, most notably acupuncture and moxibustion. Traditionally, these modalities are used in combination to augment treatment but seldom are they tested together in clinical studies. Numerous acupuncture studies have been conducted in Asia, Europe, and the United States but there have been few randomized controlled trials utilizing moxibustion outside of East Asia. Limited studies have described the use of a moxibustion control or placebo procedure...
January 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28250906/zika-virus-diseases-the-new-face-of-an-ancient-enemy-as-global-public-health-emergency-2016-brief-review-and-recent-updates
#8
REVIEW
Deepak Passi, Sarang Sharma, Shubha Ranjan Dutta, Musharib Ahmed
Zika virus (ZIKV) disease is caused by a virus transmitted by Aedes mosquito. It presents as flu-like symptoms lasting for 5-7 days and shows potential association with neurological and autoimmune complications such as congenital microcephaly and adult paralysis disorder, Guillain-Barré syndrome. Treatment measures are conservative as the disease is self-limiting. ZIKV earlier affected several tropical regions of Africa and Asia from 1951 to 2006. Subsequently, it moved out from these regions to land as outbreaks in Yap Island, French Polynesia, South America, and most recently in Brazil...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28244670/the-low-fodmap-diet-in-the-management-of-functional-dyspepsia-in-east-and-southeast-asia
#9
REVIEW
Victoria P Tan
Functional dyspepsia (FD) is a common disorder in East and Southeast Asia where subjects experience post prandial fullness/bloating, early satiety, belching, epigastric pain, and/or burning. A subset of patients with FD experience triggers exclusively related to meals, defined as the post prandial distress syndrome in the Rome IV guidelines. There is significant overlap of symptoms and implicated pathogenic factors with another common functional gastrointestinal disorder, irritable bowel syndrome (IBS) and in fact, a significant proportion of subjects have FD/IBS overlap...
March 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28243937/zika-virus-an-emerging-flavivirus
#10
REVIEW
Sang-Im Yun, Young-Min Lee
Zika virus (ZIKV) is a previously little-known flavivirus closely related to Japanese encephalitis, West Nile, dengue, and yellow fever viruses, all of which are primarily transmitted by blood-sucking mosquitoes. Since its discovery in Uganda in 1947, ZIKV has continued to expand its geographic range, from equatorial Africa and Asia to the Pacific Islands, then further afield to South and Central America and the Caribbean. Currently, ZIKV is actively circulating not only in much of Latin America and its neighbors but also in parts of the Pacific Islands and Southeast Asia...
March 2017: Journal of Microbiology / the Microbiological Society of Korea
https://www.readbyqxmd.com/read/28229289/clinical-aspects-of-hantavirus-infections-in-bulgaria
#11
I Christova, M Pishmisheva, I Trifonova, N Vatev, M Stoycheva, M Tiholova, D Igova, M Baev, R Karagyaurova, U Prokopova
BACKGROUND: Hantaviruses cause two distinct human diseases: hemorrhagic fever with renal syndrome (HFRS) in Asia and Europe and hantavirus pulmonary syndrome (HPS) in America. In Europe, mainly Puumala, Dobrava and Seoul viruses cause HFRS. A total of 23 cases of HFRS were detected in Bulgaria over a 2‑year period 2013-2014. The aim of the study was to present epidemiology, clinical manifestations and laboratory findings of these patients. METHODS: Patients with HFRS were diagnosed using PCR, ELISA and immunoblotting tests...
February 22, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/28221127/serologic-evidence-for-mers-cov-infection-in-dromedary-camels-punjab-pakistan-2012-2015
#12
Muhammad Saqib, Andrea Sieberg, Muhammad Hammad Hussain, Muhammad Khalid Mansoor, Ali Zohaib, Erik Lattwein, Marcel Alexander Müller, Christian Drosten, Victor Max Corman
Dromedary camels from Africa and Arabia are an established source for zoonotic Middle East respiratory syndrome coronavirus (MERS-CoV) infection among humans. In Pakistan, we found specific neutralizing antibodies in samples from 39.5% of 565 dromedaries, documenting significant expansion of the enzootic range of MERS-CoV to Asia.
March 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28217680/first-reported-case-of-fetal-aortic-valvuloplasty-in-asia
#13
Sun-Young Yoon, Hye-Sung Won, Mi-Young Lee, Min Kyong Cho, Euiseok Jung, Ki-Soo Kim, Young-Hwue Kim
Prenatal intervention of severe fetal aortic valve stenosis by ultrasound-guided percutaneous balloon valvuloplasty has been performed to prevent the progression to hypoplastic left heart syndrome, and achieve biventricular circulation in neonates. Here we report a case of fetal aortic valvuloplasty prenatally diagnosed with aortic stenosis at 24 weeks of gestation and showed worsening features on a follow-up echocardiography. Prenatal aortic valvuloplasty was performed at 29 weeks of gestation, and was a technical success...
January 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28211266/-non-febrile-syndromes-in-the-traveler-returning-from-tropical-regions-admitted-in-a-monographic-unit
#14
A Anula-Morales, B Martin-Giner, M Hernández-Cabrera, C Carranza-Rodríguez, E Pisos-Álamo, N Jaén-Sánchez, J L Pérez-Arellano
OBJECTIVE: The aim was to analyse those syndromes without fever in travellers who return from tropical regions evaluated at our Department of Infectology and Tropical Medicine. Clarifying these conditions intends to reach earlier diagnoses and, perhaps, to avoid the emergence and spread of imported diseases, as well as to establish appropriate preventive measures. METHODS: An observational descriptive transversal study was performed, selecting those patients who returned from tropical regions without fever (n = 281), amongst all travellers evaluated in our department between 1998 and 2013...
February 17, 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/28210295/global-impact-of-bronchiectasis-and-cystic-fibrosis
#15
REVIEW
Margarida Redondo, Holly Keyt, Raja Dhar, James D Chalmers
EDUCATIONAL AIMS: To recognise the clinical and radiological presentation of the spectrum of diseases associated with bronchiectasis.To understand variation in the aetiology, microbiology and burden of bronchiectasis and cystic fibrosis across different global healthcare systems. Bronchiectasis is the term used to refer to dilatation of the bronchi that is usually permanent and is associated with a clinical syndrome of cough, sputum production and recurrent respiratory infections. It can be caused by a range of inherited and acquired disorders, or may be idiopathic in nature...
September 2016: Breathe
https://www.readbyqxmd.com/read/28204878/unusual-onset-of-adult-still-s-disease-due-to-a%C3%A2-systemic-reaction-to-artificial-breast-implants
#16
A Wehr, G Grieb, C Trautwein, K Streetz
In this manuscript, we report an exceptional observation study of a young woman suffering from an autoimmune syndrome induced by adjuvants (ASIA). Until today only seven cases of adult-onset Still's disease (AOSD) induced by breast implants have been published. This may be due to the fact that this illness itself is very rare; however, the reason might also be that the community is not sensitized to the case-specific symptoms. Within this article, we show for the first time highly detailed diagnostic test procedures such as PET-CT scans and specific histological staining of the breast tissue, displaying proinflammatory macrophages that are a well-known activator and booster of autoimmune diseases...
February 15, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28203102/the-hla-a-31-01-allele-influence-on-carbamazepine-treatment
#17
REVIEW
Vincent Lai Ming Yip, Munir Pirmohamed
Carbamazepine (CBZ) is an effective anticonvulsant that can sometimes cause hypersensitivity reactions that vary in frequency and severity. Strong associations have been reported between specific human leukocyte antigen (HLA) alleles and susceptibility to CBZ hypersensitivity reactions. Screening for HLA-B*15:02 is mandated in patients from South East Asia because of a strong association with Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). HLA-A*31:01 predisposes to multiple phenotypes of CBZ hypersensitivity including maculopapular exanthema, hypersensitivity syndrome, and SJS/TEN in a range of populations including Europeans, Japanese, South Koreans and Han Chinese, although the effect size varies between the different phenotypes and populations...
2017: Pharmacogenomics and Personalized Medicine
https://www.readbyqxmd.com/read/28184291/human-parvovirus-4-parv4-remains-elusive-despite-a-decade-of-study
#18
REVIEW
Philippa C Matthews, Colin Sharp, Peter Simmonds, Paul Klenerman
Human parvovirus 4 ('PARV4') is a small DNA tetraparvovirus, first reported in 2005. In some populations, PARV4 infection is uncommon, and evidence of exposure is found only in individuals with risk factors for parenteral infection who are infected with other blood-borne viruses. In other settings, seroprevalence studies suggest an endemic, age-associated transmission pattern, independent of any specific risk factors. The clinical impact of PARV4 infection remains uncertain, but reported disease associations include an influenza-like syndrome, encephalitis, acceleration of HIV disease, and foetal hydrops...
2017: F1000Research
https://www.readbyqxmd.com/read/28167689/yamaguchi-syndrome-presenting-as-atrioventricular-nodal-re-entrant-tachycardia-in-an-african-american-patient
#19
Nellowe Candelario, Jorge Penalver, Mitali Sen
Apical hypertrophic cardiomyopathy (Yamaguchi syndrome) is a rare subtype of hypertrophic cardiomyopathy. The syndrome is more common in Japan where it was first described. Outside Asia, it is a very rare cause of hypertrophic cardiomyopathy. Apical hypertrophic cardiomyopathy is usually detected incidentally and has a good long-term outcome. We present a case of apical hypertrophic cardiomyopathy in an African-American patient manifesting as atrioventricular nodal re-entrant tachycardia.
February 6, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28157811/one-stage-surgical-management-for-lumbar-brucella-spondylitis-by-posterior-debridement-autogenous-bone-graft-and-instrumentation-a-case-series-of-24-patients
#20
Yangbin Chen, Jun-Song Yang, Tao Li, Peng Liu, Tuan-Jiang Liu, Li-Min He, Li-Xiong Qian, Ding-Jun Hao
STUDY DESIGN: Clinical case series. OBJECTIVE: To explore the efficacy and safety of one-stage debridement, autogenous bone graft and instrumentation for lumbar brucella spondylitis (LBS) via a posterior approach. SUMMARY OF BACKGROUND DATA: Reports on LBS are sporadic, and the therapeutic effect and safety of surgical interventions have not been assessed in clinical studies. METHODS: Between January 2012 and January 2014, 24 consecutive patients with symptomatic LBS who underwent a one-stage operation that combined debridement, autogenous bone graft and instrumentation via a posterior approach were enrolled...
February 2, 2017: Spine
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