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Zhengqiang Wang, Qianshan Ding, Yanxia Li, Qingqing Liu, Wei Wu, Lu Wu, Honggang Yu
The aim of our study is to identify microRNAs (miRNAs) that have significance in the prognosis and pathogenesis of hepatocellular carcinoma (HCC). The miRNAs differentially expressed in HCC were examined by using a human miRNA microarray dataset, and then the acquired candidates were screened by another microarray dataset. As a result, we got 25 miRNAs which were aberrantly expressed in cancer and meanwhile predicated distinct prognosis. Among them, miR-139-5p was down-regulated in HCC and its low expression in cancer tissue meant poor prognosis...
November 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
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