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Children growth

Anatole Vilhelm Wiik, Poonam Patel, Joanna Bovis, Adele Cowper, Philip Socrates Pastides, Alison Hulme, Stuart Evans, Charles Stewart
AIM: To determine if ketamine sedation is a safe and cost effective way of treating displaced paediatric radial and ulna fractures in the emergency department. METHODS: Following an agreed interdepartmental protocol, fractures of the radius and ulna (moderately to severely displaced) in children between the age of 2 and 16 years old, presenting within a specified 4 mo period, were manipulated in our paediatric emergency department. Verbal and written consent was obtained prior to procedural sedation to ensure parents were informed and satisfied to have ketamine...
March 18, 2018: World Journal of Orthopedics
Chunhong Zhang, Guomin Song, Weisheng Ye, Baoshan Xu
Osteosarcoma is one of the most frequent types of primary malignant bone neoplasm in children and adolescents. Despite advancements developed in therapeutic modalities, the 5-year overall survival rates for patients with metastatic osteosarcoma disease remain poor. The present study aimed to investigate the expression level of microRNA-302a (miR-302a) in osteosarcoma tissues and cell lines, and the biological roles of miR-302a in osteosarcoma cells. In addition, the molecular mechanism underlying its tumor suppressive roles was evaluated...
April 2018: Oncology Letters
Annelieke Hijkoop, Nina C J Peters, Rosan L Lechner, Yolande van Bever, Annabel P J M van Gils-Frijters, Dick Tibboel, René M H Wijnen, Titia E Cohen-Overbeek, Hanneke IJsselstijn
OBJECTIVES: To compare the prenatal frame of reference of omphalocele (ie, survival of fetuses) with that after birth (ie, survival of liveborn neonates), and to assess physical growth and neurodevelopment in children with minor or giant omphalocele up to 2 years of age. DESIGN: We included fetuses and neonates diagnosed in 2000-2012. Physical growth (SD scores, SDS) and mental and motor development at 12 and 24 months were analysed using general linear models, and outcomes were compared with reference norms...
March 21, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
Megan Huang, Christopher Sudfeld, Abbas Ismail, Said Vuai, Julius Ntwenya, Mary Mwanyika-Sando, Wafaie Fawzi
OBJECTIVE: To identify predictors of maternal dietary diversity in rural Dodoma, Tanzania and assess its association with child growth outcomes. METHODS: A cross-sectional survey of 361 mothers with children under 24 months of age was conducted in 5 villages in rural Dodoma, Tanzania. Maternal diets were assessed using food frequency questionnaires, and dietary diversity was categorized using Minimum Dietary Diversity for Women (MDD-W) guidelines. Child anthropometric measures were taken to calculate height-for-age z-score (HAZ), weight-for-height z-score (WHZ), and weight-for-age z-score (WAZ)...
January 1, 2018: Food and Nutrition Bulletin
Joseph E Gaugler, Mark Reese, Mary S Mittelman
Purpose of the Study: A noted limitation of dementia caregiver intervention research is a lack of focus on the mechanisms of successful programs. The purpose of this study was to conduct a process evaluation of the New York University Caregiver Intervention-Adult Child (NYUCI-AC) to describe its delivery and determine which of its components were associated with key outcomes (caregiver stress and well-being; care recipient residential care admission). Design and Methods: Adult child caregivers randomly assigned to receive the NYUCI-AC intervention (n = 54) were included...
March 19, 2018: Gerontologist
Gracinda Nogueira Oliveira, Rajiv Mohan, Andrew Fagbemi
BACKGROUND: Celiac disease is an immune-mediated disorder with a multiform presentation and therefore a challenging diagnosis. OBJECTIVE: Our purpose is to identify the epidemiological, clinical, laboratory and histologic characteristics of children with celiac disease at diagnosis and on follow-up. METHODS: Children with previously established or newly diagnosed celiac disease, admitted in a tertiary centre in a two-year period (2014-2016) were recruited...
January 2018: Arquivos de Gastroenterologia
Kylie Wheelock, Junfeng Jim Zhang, Rob McConnell, Deliang Tang, Heather E Volk, Ya Wang, Julie B Herbstman, Shuang Wang, David H Phillips, David Camann, Jicheng Gong, Frederica Perera
Polycyclic aromatic hydrocarbons (PAH) are ubiquitous air pollutants associated with negative impacts on growth, development and behavior in children. Source-specific biological markers of PAH exposure are needed for targeting interventions to protect children. Nitro-derivatives of PAH can act as markers of exposure to diesel exhaust, gasoline exhaust, or general combustion sources. Using a novel HPLC-APCI-MS/MS detection method, we examined four hemoglobin (Hb) adducts of nitro-PAH metabolites and the Hb adduct of a benzo[a]pyrene (BaP) metabolite in 22 umbilical cord blood samples...
March 21, 2018: Environmental Science. Processes & Impacts
Roghayeh Javan, Akram Kooshki, Monavvar Afzalaghaee, Mitra Aldaghi, Mahdi Yousefi
Background: Despite the decreasing rate of under nutrition children in recent years overall, the negative affect in growth and development make it as a main concern in the world. Applying an available and appropriate supplementary food is a major approach in treating children with Moderate Acute Malnutrition (MAM). Objective: To compare the effectiveness of a new supplementary blended flour (containing chickpea, rice, wheat and barley, named Shadameen) in combination with multivitamin/mineral supplement and nutritional counseling versus multivitamin/mineral supplement and nutritional counseling alone, in the treatment of children with MAM...
December 2017: Electronic Physician
Alla M Zaydman, Elena L Strokova, Elena V Kiseleva, Lubov A Suldina, Anton A Strunov, Alexander I Shevchenko, Pavel P Laktionov, Vladimir M Subbotin
Idiopathic scoliosis is one of the most common disabling pathologies of children and adolescents. Etiology and pathogenesis of idiopathic scoliosis remain unknown. To study the etiology of this disease we identified the cells' phenotypes in the vertebral body growth plates in patients with idiopathic scoliosis. Materials and methods: The cells were isolated from vertebral body growth plates of the convex and concave sides of the deformity harvested intraoperatively in 50 patients with scoliosis. Cells were cultured and identified by methods of common morphology, neuromorphology, electron microscopy, immunohistochemistry and PCR analysis...
2018: International Journal of Medical Sciences
William F Waters, Carlos Andres Gallegos, Celia Karp, Chessa Lutter, Christine Stewart, Lora Iannotti
BACKGROUND: Food-based interventions can reduce the prevalence of undernutrition and improve household food security, but nutritious and accessible foods may be underutilized. In Ecuador, eggs are inexpensive and widely available, but while they are a valuable source of essential nutrients for infants and young children, medical advice and community-based information have limited their inclusion in infants' diets. OBJECTIVE: A qualitative component was conducted to understand local perceptions, knowledge, and practices to complement a randomized control trial that studied the effect of introducing eggs on nutritional status and growth in infants from 6 to 9 months in rural communities in the highland province of Cotopaxi, Ecuador...
January 1, 2018: Food and Nutrition Bulletin
Enju Liu, Laura Pimpin, Masha Shulkin, Sarah Kranz, Christopher P Duggan, Dariush Mozaffarian, Wafaie W Fawzi
(1) Background: The effects of zinc supplementation on child growth, and prior reviews of these studies, have shown mixed results. We aim to systematically review and meta-analyze randomized controlled trials evaluating effects of preventive zinc supplementation for 3 months or longer during pregnancy or in children up to age 5 years on pregnancy outcomes and child growth; (2) Methods: We searched PubMed, EMBASE, Cochrane Library, Web of Science, and trial registries for eligible trials up to October 10, 2017...
March 20, 2018: Nutrients
Izabela Łaczmańska, Justyna Kuliczkowska-Płaksej, Agnieszka Stembalska
Short stature, which is defined as height below 2 standard deviations of the mean height for the age and sex, is one of the most frequent reasons for medical consultations in children. Short stature may occur due to a constitutional delay in growth, familial short stature or chronic diseases, including many genetic syndromes, metabolic and endocrine disorders. In this article the authors provide a mini-review of the most frequent genetic syndromes associated with short stature that should be taken into account in the differential diagnosis process...
March 14, 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Alma V Huidobro-Chávez, Gianmarco D Vigo Pareja, Carlos Pachas-Peña, Karina Patiño-Calla
The Langerhans cell histiocytosis is a rare disease characterized by the clonal proliferation of CD1a + myeloid dendritic cells associated with a significant inflammatory component. The localized form of the disease is called eosinophilic granuloma. Bone involvement is common; in children, lytic lesions are most frequently found in the cranial dome being rare in the orbit. We present an 18-month-old infant who consulted due to periorbital edema and proptosis of the right eye, with two months of evolution. The computed tomography and the magnetic resonance imaging showed a maxillary sinus tumor mass of expansive growth and erosion of the roof of the orbit...
April 1, 2018: Archivos Argentinos de Pediatría
Edilberto Díaz Bonilla, Claudia L Torres Galvis, Rossana Gómez Campos, Miguel de Arruda, Jaime Pacheco Carrillo, Marco Cossio Bolaños
INTRODUCTION: There is increasing concern over the study of physical growth in different regions of the world, although altitude is not considered an adjustment factor. OBJECTIVES: Compare physical growth variables and body mass index (BMI) patterns with the Centers for Disease Control and Prevention (CDC) 2012 reference data and develop percentiles for children and adolescents. METHODOLOGY: School children living at moderate altitude in Bogotá (Colombia) were studied...
April 1, 2018: Archivos Argentinos de Pediatría
Tatiana M Lanzieri, Winnie Chung, Jessica Leung, A Chantal Caviness, Jason L Baumgardner, Peggy Blum, Stephanie R Bialek, Gail Demmler-Harrison
Objectives To compare hearing trajectories among children with symptomatic and asymptomatic congenital cytomegalovirus infection through age 18 years and to identify brain abnormalities associated with sensorineural hearing loss (SNHL) in asymptomatic case patients. Study Design Longitudinal prospective cohort study. Setting Tertiary medical center. Subjects and Methods The study included 96 case patients (4 symptomatic and 92 asymptomatic) identified through hospital-based newborn cytomegalovirus screening from 1982 to 1992 and 72 symptomatic case patients identified through referrals from 1993 to 2005...
February 1, 2018: Otolaryngology—Head and Neck Surgery
Tali Sinai, Shely Ben-Avraham, Inbal Guelmann-Mizrahi, Michael R Goldberg, Larisa Naugolni, Galia Askapa, Yitzhak Katz, Marianna Rachmiel
PURPOSE: The use of soy products is common in young children with cow milk allergy (CMA). The aim was to examine prospectively the association between infantile consumption of soy-based formula, growth parameters and early pubertal signs, in comparison to cow milk-based formula. METHODS: A nested case-control study was conducted, selected from a cohort of infants prospectively followed from birth until the age of 3 years for eating habits and the development of IgE-mediated CMA...
March 20, 2018: European Journal of Nutrition
Harold S Matthews, Anthony J Penington, Rita Hardiman, Yi Fan, John G Clement, Nicola M Kilpatrick, Peter D Claes
Many disorders present with characteristic abnormalities of the craniofacial complex. Precise descriptions of how and when these abnormalities emerge and change during childhood and adolescence can inform our understanding of their underlying pathology and facilitate diagnosis from craniofacial shape. In this paper we develop a framework for analysing how anatomical differences between populations emerge and change over time, and for binary group classification that adapts to the age of each participant. As a proxy for a disease-control comparison we use a database of 3D photographs of normally developing boys and girls to examine emerging sex-differences...
March 19, 2018: Scientific Reports
Ann-Katrin Meyrose, Fionna Klasen, Christiane Otto, Gabriela Gniewosz, Thomas Lampert, Ulrike Ravens-Sieberer
RATIONALE: Mental health problems in children and adolescents are widespread and are a primary public health concern worldwide. During childhood and adolescence different challenges must be met. Whether the corresponding developmental tasks can be mastered successfully and in a psychologically healthy manner depends on the availability of resources. OBJECTIVE: The aim of the current study was to examine the benefits of maternal education on the development of mental health in children and adolescents...
February 24, 2018: Social Science & Medicine
Yujing Huang, Jia Wang, Yao Tan, Lingqiao Wang, Hui Lin, Lan Lan, Yu Xiong, Wei Huang, Weiqun Shu
Although direct drinking water (DDW) systems that utilize a reverse-osmosis technique are thought to be harmful to children's development by reducing their daily mineral intake, few population data are available regarding this topic. We conducted an eco-epidemiological study to investigate the influence of low-mineral DDW on the development of schoolchildren. We collected developmental parameters of 13,723 girls and 16,161 boys before and after the introduction of DDW systems in 25 schools and measured the mineral levels in the DDW of each school...
March 16, 2018: Environment International
Cyril S Gary, Sharon Marczewski, Patricia M Vitagliano, Rajendra Sawh-Martinez, Robin Wu, Derek M Steinbacher
Mandibular distraction osteogenesis (MDO) is an effective treatment modality for children suffering from upper airway obstruction from Robin Sequence (RS). Mandibular distraction osteogenesis has been shown to have positive effects on oral feeding and for relieving respiratory obstruction, but its effects on postoperative weight gain are poorly understood. This study quantitatively analyzes weight gain following MDO. A retrospective chart review identified 22 RS children who underwent MDO. Patient weight data, feeding methods pre- and postoperatively, and polysomnography data pre- and postoperatively were collected...
March 16, 2018: Journal of Craniofacial Surgery
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