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https://www.readbyqxmd.com/read/28107472/fractionation-of-magnetic-microspheres-in-a-microfluidic-spiral-interplay-between-magnetic-and-hydrodynamic-forces
#1
S Dutz, M E Hayden, U O Häfeli
Magnetic forces and curvature-induced hydrodynamic drag have both been studied and employed in continuous microfluidic particle separation and enrichment schemes. Here we combine the two. We investigate consequences of applying an outwardly directed magnetic force to a dilute suspension of magnetic microspheres circulating in a spiral microfluidic channel. This force is realized with an array of permanent magnets arranged to produce a magnetic field with octupolar symmetry about the spiral axis. At low flow rates particles cluster around an apparent streamline of the flow near the outer wall of the turn...
2017: PloS One
https://www.readbyqxmd.com/read/28107204/non-invasive-blood-glucose-detection-system-based-on-conservation-of-energy-method
#2
Yang Zhang, Jian-Ming Zhu, Yong-Bo Liang, Hong-Bo Chen, Shi-Min Yin, Zhen-Cheng Chen
The most common method used for minimizing the occurrence of diabetes complications is frequent glucose testing to adjust the insulin dose. However, using blood glucose (BG) meters presents a risk of infection. It is of great importance to develop non-invasive BG detection techniques. To realize high-accuracy, low-cost and continuous glucose monitoring, we have developed a non-invasive BG detection system using a mixed signal processor 430 (MSP430) microcontroller. This method is based on the combination of the conservation-of-energy method with a sensor integration module, which collects physiological parameters, such as the blood oxygen saturation (SPO2), blood flow velocity and heart rate...
January 20, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28106465/evaluation-of-99m-tc-mibi-in-thyroid-gland-imaging-for-the-diagnosis-and-classification-of-amiodarone-induced-thyrotoxicosis
#3
Junqi Wang, Ruiguo Zhang
OBJECTIVE: Amiodarone-induced thyrotoxicosis (AIT) is caused by aminodaroneas a side effect of cardiovascular disease treatment. Based on the differences in their pathological and physiological mechanisms, many methods have been developed so far to differentiate AIT subtypes such as color flow Doppler sonography (CFDS)and 24 h radioiodine uptake (RAIU). However, these methods suffer from inadequate accuracy in distinguishing different types of AITs and sometimes lead to misdiagnosis and delayed treatments...
January 20, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28106317/changes-in-vascular-reactivity-and-endothelial-ca-2-dynamics-with-chronic-low-flow
#4
Mark S Taylor, Chung-Sik Choi, Leith Bayazid, Katherine E Glosemeyer, Calvin C P Baker, David S Weber
Disruption of blood flow promotes endothelial dysfunction and predisposes vessels to remodeling and atherosclerosis. Recent findings suggest spatial and temporal tuning of local Ca(2+) signals along the endothelium is vital to vascular function. In the current study, we examined whether chronic flow disruption causes alteration of dynamic endothelial Ca(2+) signal patterning associated with changes in vascular structure and function. For these studies, we performed surgical partial-ligation (PL) of the left carotid arteries of mice to establish chronic low flow for 2 weeks; right carotid arteries remained open and served as controls (C)...
January 20, 2017: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/28106228/expression-of-long-non-coding-rna-pandar-and-its-prognostic-value-in-colorectal-cancer-patients
#5
Xiangke Li, Feng Wang, Yan Sun, Qingxia Fan, Guangfei Cui
BACKGROUND: Long noncoding RNAs (lncRNAs) are emerging as key molecules in human cancer. In the present study, we explored the role of the lncRNA PANDAR in colorectal cancer (CRC). METHODS: The relative expression level of lncRNA PANDAR in CRC tissues and cell lines was determined by quantitative real-time polymerase chain reaction (qRT-PCR). The associations between PANDAR expression and clinicopathological features of CRC patients were further analyzed. Kaplan-Meier survival analysis was performed to evaluate the value of PANDAR in the prognosis of CRC patients...
January 20, 2017: International Journal of Biological Markers
https://www.readbyqxmd.com/read/28106129/retooling-laser-speckle-contrast-analysis-algorithm-to-enhance-non-invasive-high-resolution-laser-speckle-functional-imaging-of-cutaneous-microcirculation
#6
Surya C Gnyawali, Kevin Blum, Durba Pal, Subhadip Ghatak, Savita Khanna, Sashwati Roy, Chandan K Sen
Cutaneous microvasculopathy complicates wound healing. Functional assessment of gated individual dermal microvessels is therefore of outstanding interest. Functional performance of laser speckle contrast imaging (LSCI) systems is compromised by motion artefacts. To address such weakness, post-processing of stacked images is reported. We report the first post-processing of binary raw data from a high-resolution LSCI camera. Sharp images of low-flowing microvessels were enabled by introducing inverse variance in conjunction with speckle contrast in Matlab-based program code...
January 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28105958/dmirnet-inferring-direct-microrna-mrna-association-networks
#7
Minsu Lee, HyungJune Lee
BACKGROUND: MicroRNAs (miRNAs) play important regulatory roles in the wide range of biological processes by inducing target mRNA degradation or translational repression. Based on the correlation between expression profiles of a miRNA and its target mRNA, various computational methods have previously been proposed to identify miRNA-mRNA association networks by incorporating the matched miRNA and mRNA expression profiles. However, there remain three major issues to be resolved in the conventional computation approaches for inferring miRNA-mRNA association networks from expression profiles...
December 5, 2016: BMC Systems Biology
https://www.readbyqxmd.com/read/28105847/compact-ultrahigh-pressure-nanoflow-capillary-liquid-chromatograph
#8
Xiaofeng Zhao, Xiaofeng Xie, Sonika Sharma, Luke T Tolley, Alex Plistil, Hal E Barnett, Martin P Brisbin, Adam C Swensen, John C Price, Paul B Farnsworth, H Dennis Tolley, Stanley D Stearns, Milton L Lee
A compact ultrahigh-pressure nanoflow liquid chromatograph (LC) was developed with the purpose in mind of creating a portable system that could be easily moved to various testing locations or placed in close proximity to other instruments for optimal coupling, such as with mass spectrometry (MS). The system utilized innovative nanoflow pumps integrated with a very low volume stop-flow injector and mixing tee. The system weighed only 5.9 kg (13 lbs) or 4.5 kg (10 lbs) without a controller and could hold up to 1100 bar (16000 psi) of pressure...
January 3, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28105595/bioelectrochemical-anaerobic-sewage-treatment-technology-for-arctic-communities
#9
Boris Tartakovsky, Yehuda Kleiner, Michelle-France Manuel
This study describes a novel wastewater treatment technology suitable for small remote northern communities. The technology is based on an enhanced biodegradation of organic carbon through a combination of anaerobic methanogenic and microbial electrochemical (bioelectrochemical) degradation processes leading to biomethane production. The microbial electrochemical degradation is achieved in a membraneless flow-through bioanode-biocathode setup operating at an applied voltage below the water electrolysis threshold...
January 20, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28104978/maximizing-the-endosonography-the-role-of-contrast-harmonics-elastography-and-confocal-endomicroscopy
#10
REVIEW
Andrada Seicean, Ofelia Mosteanu, Radu Seicean
New technologies in endoscopic ultrasound (EUS) evaluation have been developed because of the need to improve the EUS and EUS-fine needle aspiration (EUS-FNA) diagnostic rate. This paper reviews the principle, indications, main literature results, limitations and future expectations for each of the methods presented. Contrast-enhanced harmonic EUS uses a low mechanical index and highlights slow-flow vascularization. This technique is useful for differentiating solid and cystic pancreatic lesions and assessing biliary neoplasms, submucosal neoplasms and lymph nodes...
January 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28104897/optimal-flow-rate-sampling-designs-for-studies-with-extended-exhaled-nitric-oxide-analysis
#11
Noa Molshatzki, Sandrah Eckel
INTRODUCTION: The fractional concentration of exhaled nitric oxide (FeNO) is a biomarker of airway inflammation. Repeat FeNO maneuvers at multiple fixed exhalation flow rates (extended NO analysis) can be used to estimate parameters quantifying proximal and distal sources of NO in mathematical models of lower respiratory tract NO. A growing number of studies use extended NO analysis, but there is no official standard flow rate sampling protocol. In this paper, we provide information for study planning by deriving theoretically optimal flow rate sampling designs...
January 20, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28104642/evaluation-of-encephaloduroarteriosynangiosis-efficacy-using-probabilistic-independent-component-analysis-applied-to-dynamic-susceptibility-contrast-perfusion-mri
#12
A N Laiwalla, F Kurth, K Leu, R Liou, J Pamplona, Y C Ooi, N Salamon, B M Ellingson, N R Gonzalez
BACKGROUND AND PURPOSE: Indirect cerebral revascularization has been successfully used for treatment in Moyamoya disease and symptomatic intracranial atherosclerosis. While angiographic neovascularization has been demonstrated after surgery, measurements of local tissue perfusion are scarce and may not reflect the reported successful clinical outcomes. We investigated probabilistic independent component analysis and conventional perfusion parameters from DSC-MR imaging to measure postsurgical changes in tissue perfusion...
January 19, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28103875/effects-of-plasmodium-falciparum-infection-on-umbilical-artery-resistance-and-intrafetal-blood-flow-distribution-a-doppler-ultrasound-study-from-papua-new-guinea
#13
Maria Ome-Kaius, Stephan Karl, Regina Alice Wangnapi, John Walpe Bolnga, Glen Mola, Jane Walker, Ivo Mueller, Holger Werner Unger, Stephen John Rogerson
BACKGROUND: Doppler velocimetry studies of umbilical artery (UA) and middle cerebral artery (MCA) flow help to determine the presence and severity of fetal growth restriction. Increased UA resistance and reduced MCA pulsatility may indicate increased placental resistance and intrafetal blood flow redistribution. Malaria causes low birth weight and fetal growth restriction, but few studies have assessed its effects on uteroplacental and fetoplacental blood flow. METHODS: Colour-pulsed Doppler ultrasound was used to assess UA and MCA flow in 396 Papua New Guinean singleton fetuses...
January 19, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28103645/prognostic-impact-of-lymphocyte-subpopulations-in-peripheral-blood-after-hematopoietic-stem-cell-transplantation-for-hematologic-malignancies
#14
Sang Hyuk Park, Chan-Jeoung Park, Borae G Park, Mi-Hyun Bae, Bo-Hyun Kim, Young-Uk Cho, Seongsoo Jang, Ae Ja Park, Dae-Young Kim, Jung-Hee Lee, Je-Hwan Lee, Kyoo-Hyung Lee
BACKGROUND: We prospectively evaluated prognostic value of lymphocyte subpopulations in peripheral blood of allogeneic hematopoietic stem cell transplant (HSCT)-recipients. METHODS: 113 allogeneic HSCT (47 sibling matched, 37 unrelated matched, 29 haploidentical)-performed patients diagnosed as AML (n=66), ALL (n=28) and MDS (n=19) were prospectively enrolled. 14 lymphocyte subpopulations were quantified by flow cytometry of PB at specific time-points after HSCT, and their prognostic impacts were analyzed...
January 19, 2017: Cytometry. Part B, Clinical Cytometry
https://www.readbyqxmd.com/read/28103586/selective-area-growth-of-periodic-nanopyramid-light-emitting-diode-arrays-on-gan-sapphire-templates-patterned-by-multiple-exposure-colloidal-lithography
#15
Zhuo Xiong, Tongbo Wei, Yonghui Zhang, Xiang Zhang, Chao Yang, Zhiqiang Liu, Guodong Yuan, Jinmin Li, Junxi Wang
Gallium nitride-based nanopyramid light-emitting diodes are a promising technology to achieve highly efficient solid-state lighting and beyond. Here, periodic nanopyramid light-emitting diode arrays on gallium nitride/sapphire templates were fabricated by selective-area metalorganic chemical vapor deposition and multiple-exposure colloidal lithography. The electric field intensity distribution of incident light going through polystyrene microspheres and photoresist are simulated using finite-different time-domain method...
January 19, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28103551/ultrasound-flow-mapping-for-the-investigation-of-crystal-growth
#16
Norman Thieme, Paul Bonisch, Dagmar Meier, Richard Nauber, Lars Buttner, Kaspars Dadzis, Olf Patzold, Lamine Sylla, Jurgen Czarske
A high energy conversion and cost efficiency are keys for the transition to renewable energy sources, e.g. solar cells. The efficiency of multi-crystalline solar cells can be improved by enhancing the understanding of its crystallization process, especially the directional solidification. In this paper, a novel measurement system for the characterization of flow phenomena and solidification processes in low-temperature model experiments on the basis of ultrasound Doppler velocimetry is described. It captures turbulent flow phenomena in two planes with a frame rate of 3...
January 16, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28103270/cold-atmospheric-plasma-created-at-the-tip-of-an-elongated-flexible-capillary-using-low-electric-current-can-slow-the-progression-of-melanoma
#17
Y Binenbaum, G Ben-David, Z Gil, Ya Z Slutsker, M A Ryzhkov, J Felsteiner, Ya E Krasik, J T Cohen
INTRODUCTION: Cold Atmospheric Plasma Jet (CAPJ), with ion temperature close to room temperature, has tremendous potential in biomedical engineering, and can potentially offer a therapeutic option that allows cancer cell elimination without damaging healthy tissue. We developed a hand-held flexible device for the delivery of CAPJ to the treatment site, with a modified high-frequency pulse generator operating at a RMS voltage of <1.2 kV and gas flow in the range 0.3-3 l/min. The aims of our study were to characterize the CAPJ emitted from the device, and to evaluate its efficacy in elimination of cancer cells in-vitro and in-vivo...
2017: PloS One
https://www.readbyqxmd.com/read/28102497/regulated-partitioning-of-fixed-carbon-14-c-sodium-na-potassium-k-and-glycine-betaine-determined-salinity-stress-tolerance-of-gamma-irradiated-pigeonpea-cajanus-cajan-l-millsp
#18
Pankaj Kumar, Vasundhara Sharma, Chobhe Kapil Atmaram, Bhupinder Singh
Soil salinity is a major constraint that limits legume productivity. Pigeonpea is a salt sensitive crop. Seed gamma irradiation at a very low dose (2.5 Gy) is known to enhance seedling establishment, plant growth and yield of cereals and other crops. The present study conducted using two genetically diverse varieties of pigeonpea viz., Pusa-991 and Pusa-992 aimed at establishing the role of pre-sowing seed gamma irradiation at 0, 0.0025, 0.005, 0.01, 0.02, 0.05 and 0.1 kGy on plant growth, seed yield and seed quality under salt stress at 0, 80 and 100 mM NaCl (soil solution EC equivalent 1...
January 19, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28102303/panmixia-and-dispersal-from-the-mediterranean-basin-to-macaronesian-islands-of-a-macrolichen-species
#19
David Alors, Francesco Dal Grande, Paloma Cubas, Ana Crespo, Imke Schmitt, M Carmen Molina, Pradeep K Divakar
The Mediterranean region, comprising the Mediterranean Basin and the Macaronesian Islands, represents a center of diversification for many organisms. The genetic structure and connectivity of mainland and island microbial populations has been poorly explored, in particular in the case of symbiotic fungi. Here we investigated genetic diversity and spatial structure of the obligate outcrossing lichen-forming fungus Parmelina carporrhizans in the Mediterranean region. Using eight microsatellite and mating-type markers we showed that fungal populations are highly diverse but lack spatial structure...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28102178/fast-synthesis-of-ultrathin-zno-nanowires-by-oxidation-of-cu-zn-stacks-in-low-pressure-afterglow
#20
A Altaweel, A Imam, J Ghanbaja, D Mangin, P Miska, T Gries, T Belmonte
The synthesis of ultrathin, single-crystalline zinc oxide nanowires was achieved by treating in a flowing microwave plasma oxidation process, zinc films coated beforehand by a sputtered thin buffer layer of copper. The aspect ratio of the nanowires can be controlled by the following experimental parameters: treatment duration, furnace temperature, oxygen concentration. An average diameter of 6 nm correlated with a mean length of 750 nm can be reached with a fairly high surface number density for very short treatments, typically less than 1 min...
January 19, 2017: Nanotechnology
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