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https://www.readbyqxmd.com/read/29147978/predictors-of-client-satisfaction-with-outpatient-mental-health-clinic-services-in-italy-and-new-york
#1
Luca Pauselli, Chiara Galletti, Norma Verdolini, Enrico Paolini, Daniela Gallucci, Pierfrancesco Maria Balducci, Francesco Bernardini, Jerome H Kogan, Ruth Shim, Patrizia Moretti, Michael T Compton
The aim of this cross-sectional study was to assess factors associated with client satisfaction in two mental health outpatient settings in Italy and the US. Sociodemographic and clinical variables, hope, and personality characteristics were evaluated in 18-65-year-old patients who had been receiving services for at least 2 months in one of two outpatient clinics, in Italy and the US. Patients were administered: the Healthy Days Core Module, the Kessler Screening Scale for Psychological Distress, the Verona Service Satisfaction Survey, the Client Satisfaction Inventory, the Health Service OutPatient Experience questionnaire, the Herth Hope Index, and the NEO Five-Factor Inventory-3...
November 17, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/29146037/comparative-effectiveness-research-methodology-using-secondary-data-a-starting-user-s-guide
#2
REVIEW
Maxine Sun, Stuart R Lipsitz
BACKGROUND: The use of secondary data, such as claims or administrative data, in comparative effectiveness research has grown tremendously in recent years. PURPOSE: We believe that the current review can help investigators relying on secondary data to (1) gain insight into both the methodologies and statistical methods, (2) better understand the necessity of a rigorous planning before initiating a comparative effectiveness investigation, and (3) optimize the quality of their investigations...
November 13, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/29145822/ultrasonographic-parameters-of-the-liver-spleen-and-kidneys-among-a-cohort-of-school-children-in-sri-lanka
#3
Dianne Tania Dayanthi Warnakulasuriya, Pattiya Pathirennahalage Uddika Chamila Peries, Yaddehi Arachchillage Chaminda Rathnasekara, KaluArachchige Thushari Madurika Jayawardena, Angappulige Upasena, Anada Rajitha Wickremasinghe
BACKGROUND: Liver, spleen and kidney dimensions on ultrasonography vary with the age, weight and ethnicity. Reference standards of these parameters for normal Sri Lankan children are not available. Our aim was to establish normative data for longitudinal length of liver, spleen and kidneys in healthy children. METHOD: Three hundred fifty-seven children, 5-13 years of age were selected from two randomly selected schools in the Gampaha district in the western province of Sri Lanka...
November 16, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/29143775/low-cost-air-quality-monitoring-tools-from-research-to-practice-a-workshop-summary
#4
REVIEW
Andrea L Clements, William G Griswold, Abhijit Rs, Jill E Johnston, Megan M Herting, Jacob Thorson, Ashley Collier-Oxandale, Michael Hannigan
In May 2017, a two-day workshop was held in Los Angeles (California, U.S.A.) to gather practitioners who work with low-cost sensors used to make air quality measurements. The community of practice included individuals from academia, industry, non-profit groups, community-based organizations, and regulatory agencies. The group gathered to share knowledge developed from a variety of pilot projects in hopes of advancing the collective knowledge about how best to use low-cost air quality sensors. Panel discussion topics included: (1) best practices for deployment and calibration of low-cost sensor systems, (2) data standardization efforts and database design, (3) advances in sensor calibration, data management, and data analysis and visualization, and (4) lessons learned from research/community partnerships to encourage purposeful use of sensors and create change/action...
October 28, 2017: Sensors
https://www.readbyqxmd.com/read/29142803/unprovoked-pulmonary-embolism-in-a-young-patient-with-marfan-syndrome
#5
Stella Pak, Andrew Kilgore, Rosanne Thornhill, Kyle Rako, Ali Meier, Gavriella Pora, Jillian M Costello, Christine Dee
Marfan syndrome is a rare connective tissue disorder with a prevalence of approximately 2 to 3 per 10,000 individuals. There have been some reports of young patients with Marfan syndrome developing arteriovenous thromboembolism. These events were unprovoked and recurrent. Owing to its rarity, hypercoagulopathy and other metabolic derangement in patients with Marfan syndrome remains largely unknown. Herein, we report a case of a young man with Marfan syndrome who had myocardial infarction and pulmonary embolism...
September 5, 2017: Curēus
https://www.readbyqxmd.com/read/29142459/a-phase-i-study-of-different-doses-and-frequencies-of-pegylated-recombinant-human-granulocyte-colony-stimulating-factor-peg-rhg-csf-in-patients-with-standard-dose-chemotherapy-induced-neutropenia
#6
Yan Qin, Xiaohong Han, Lin Wang, Ping Du, Jiarui Yao, Di Wu, Yuanyuan Song, Shuxiang Zhang, Le Tang, Yuankai Shi
Objective: The recommended dose of prophylactic pegylated recombinant human granulocyte-colony stimulating factor (PEG rhG-CSF) is 100 μg/kg once per cycle for patients receiving intense-dose chemotherapy. However, few data are available on the proper dose for patients receiving less-intense chemotherapy. The aim of this phase I study is to explore the proper dose and administration schedule of PEG rhG-CSF for patients receiving standard-dose chemotherapy. Methods: Eligible patients received 3-cycle chemotherapy every 3 weeks...
October 2017: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/29140952/-don-t-lose-hope-early-hemorrhagic-diffuse-axonal-injury-on-head-ct-is-not-associated-with-poor-outcome-in-moderate-severe-tbi-patients
#7
Nils Henninger, Rebecca A Compton, Muhammad W Khan, Raphael Carandang, Wiley Hall, Susanne Muehlschlegel
BACKGROUND: Diffuse axonal injury (DAI) on MRI has been associated with poor functional outcome after moderate-severe traumatic brain injury (msTBI). Yet, DAI assessment with highly-sensitive MRI-techniques is unfeasible in the acute trauma setting, and CT remains the key diagnostic modality despite its lower sensitivity. We sought to determine whether CT-defined-hemorrhagic-DAI (hDAI) is associated with discharge and favorable 3-and 12-month functional outcome (Glasgow Outcome Score ≥4) after msTBI...
November 14, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29138012/systematic-review-on-reporting-quality-of-randomized-controlled-trials-in-patients-with-hepatitis-b-or-c-in-china
#8
Na Zeng, Cailun Zou, Zhiying He, Hong Ma, Xiaojuan Ou, Hong You, Yuanyuan Kong, Jidong Jia
BACKGROUND: Randomized controlled trails (RCTs) on viral hepatitis in China have been increasing, but few studies have been systematically conducted to evaluate the reporting quality of RCTs in this field. In the present study, we assessed the reporting quality of RCTs on the treatment of hepatitis B or C from 1991 to 2015 in China. METHODS: Articles published between January 1991 and December 2015 were identified via PubMed, Medline, and Embase by using the key words "randomized clinical trials," "treatment," "therapy," "hepatitis B," "HBV," "hepatitis C," "HCV," "China," and "Chinese...
November 11, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29137836/how-participatory-action-research-changed-our-view-of-the-challenges-of-shared-decision-making-training
#9
Jette Ammentorp, Maiken Wolderslund, Connie Timmermann, Henry Larsen, Karina Dahl Steffensen, Annegrethe Nielsen, Marianne E Lau, Bodil Winther, Lars Henrik Jensen, Elisabeth Assing Hvidt, Niels Christian Hvidt, Pål Gulbrandsen
OBJECTIVE: This paper aims to demonstrate how the use of participatory action research (PAR) helped us identify ways to respond to communication challenges associated with shared decision-making (SDM) training. METHODS: Patients, relatives, researchers, and health professionals were involved in a PAR process that included: (1) two theatre workshops, (2) a pilot study of an SDM training module involving questionnaires and evaluation meetings, and (3) three reflection workshops...
November 9, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/29136011/ten-year-experience-with-antiretroviral-treatment-in-cambodia-trends-in-patient-characteristics-and-treatment-outcomes
#10
Phirum Lay, Sokkab An, Sunpiseth Soeung, Pich Sovannary Srey, Sopheak Thai, Lutgarde Lynen, Johan van Griensven
BACKGROUND: Although HIV disease stage at ART initiation critically determines ART outcomes, few reports have longitudinally monitored this within Asia. Using prospectively collected data from a large ART program at Sihanouk Hospital Center of Hope in Cambodia, we report on the change in patient characteristics and outcomes over a ten-year period. METHODS: We conducted a retrospective analysis including all adults (≥ 18 years old) starting ART from March 2003-March 2013 in a non-governmental hospital in Phnom Penh, Cambodia...
2017: PloS One
https://www.readbyqxmd.com/read/29135236/photoelectrochemical-immunoassays
#11
Wei-Wei Zhao, Jing-Juan Xu, Hong-Yuan Chen
As an essential direction of photoelectrochemical (PEC) bioanalysis, PEC immunoassays have attracted substantial research scrutiny for its desirable combination of the inherent sensitivity of the PEC bioanalysis and the specific bioaffinity properties of the immunomolecules. The past five years have witnessed substantial advances toward the development of PEC immunoassays, and numerous approaches to advanced PEC immunoassays have been established. Although the summaries on specific topics, such as the PEC DNA biosensors, PEC aptasensing, PEC enzymatic biosensors or the general development of PEC bioanalysis, have been presented in previous reviews, no in-depth survey has yet been made for addressing specifically on the important category of PEC immunoassays...
November 14, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29135145/-aesthetic-criteria-in-surgical-treatment-of-hypospadias-in-children
#12
G V Kozyrev, A A Protasov, V V Nikolaev, F K Abdullaev, G A Abdulkarimov, M E Karmanov
Aesthetically acceptable cosmetic results of surgical correction of external genital organ defects are important for treatment evaluation along with well-known criteria of good functional outcomes.The purpose of this study was to improve the results of treating children with hypospadias by improving the assessment of results and introducing multi-step correction modalities. MATERIALS AND METHODS: From 2013 to 2015, 476 patients with various forms of hypospadias were treated at the Department of Uroandrology of RCCH...
October 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29133283/open-source-electronic-health-record-systems-for-low-resource-settings-systematic-review
#13
REVIEW
Assel Syzdykova, André Malta, Maria Zolfo, Ermias Diro, José Luis Oliveira
BACKGROUND: Despite the great impact of information and communication technologies on clinical practice and on the quality of health services, this trend has been almost exclusive to developed countries, whereas countries with poor resources suffer from many economic and social issues that have hindered the real benefits of electronic health (eHealth) tools. As a component of eHealth systems, electronic health records (EHRs) play a fundamental role in patient management and effective medical care services...
November 13, 2017: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29128470/is-it-worth-it-or-possible-to-measure-what-matters-to-patients-with-epilepsy-and-their-caregivers
#14
Maria Grazia Celani, Teresa Anna Cantisani, Angelo Bignamini, Sara Macone, Rossella Papetti, Luisa Baiocco
OBJECTIVE: The objective of this study was to collect perspectives, ideas, and values of people affected by epilepsy and their carer to include them in new research in this area. DESIGN: This is a semiquantitative study analyzing needs, emotions, and medical issues emerging from focus groups with patients and carers divided in three severity levels of disease. PARTICIPANTS: The participants were 25 patients and 36 carers attending outpatients' service of tertiary epilepsy center in Umbria, Italy...
November 8, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29125878/insight-into-the-interactions-residue-snorkeling-and-membrane-disordering-potency-of-a-single-antimicrobial-peptide-into-different-lipid-bilayers
#15
Majid Jafari, Faramarz Mehrnejad, Farahnoosh Doustdar
Pardaxin, with a bend-helix-bend-helix structure, is a membrane-active antimicrobial peptide that its membrane activity depends on the lipid bilayer composition. Herein, all-atom molecular dynamics (MD) simulations were performed to provide further molecular insight into the interactions, structural dynamics, orientation behavior, and cationic residues snorkeling of pardaxin in the DMPC, DPPC, POPC, POPG, POPG/POPE (3:1), and POPG/POPE (1:3) lipid bilayers. The results showed that the C-terminal helix of the peptide was maintained in all six types of the model-bilayers and pardaxin was tilted into the DMPC, DPPC, and POPG/POPE mixed bilayers more than the POPC and POPG bilayers...
2017: PloS One
https://www.readbyqxmd.com/read/29123352/spiritual-needs-and-quality-of-life-of-patients-with-cancer
#16
Mansooreh Azizzadeh Forouzi, Batool Tirgari, Mohammad Hossein Safarizadeh, Yunes Jahani
Background and Aim: Information about spiritual needs and quality of life (QoL) is limited in Iranian cancer patients. This study was conducted to determine the relationship between spiritual needs and QoL among cancer patients in Iran. Methods: This correlational study included a convenience sample of 150 eligible cancer patients who were hospitalized in the oncology wards and outpatient clinics. Using two questionnaires; the spiritual needs survey and the European Organization for Research and Treatment of Cancer QoL Questionnaire-C30 data were collected...
October 2017: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/29122582/biorelevant-media-slows-the-solution-mediated-phase-transformation-of-amorphous-spironolactone
#17
Mary S Kleppe, Roy J Haskell, Robin H Bogner
Solution-mediated phase transformation (SMPT) can reduce the high drug concentration expected from amorphous formulations, eliminating the improvement in drug absorption one hoped to gain from this high energy drug state. The differences in SMPT of a supersaturating system were compared in biorelevant media (Fasted State Simulated Intestinal Fluid (FaSSIF) and Fed State Simulated Intestinal Fluid (FeSSIF)) and USP compendial medium, Simulated Intestinal Fluid without pancreatin (SIFsp). Amorphous spironolactone underwent SMPT to the same hydrate of spironolactone in all three media which was confirmed by the decrease in dissolution rates assessed in a flow-through dissolution apparatus, as well as by the appearance of crystals on the amorphous solid surface detected by polarized light microscopy...
November 6, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29122129/a-new-algorithm-for-crossing-chronic-total-occlusions-from-the-asia-pacific-chronic-total-occlusion-club
#18
REVIEW
Scott A Harding, Eugene B Wu, Sidney Lo, Soo Teik Lim, Lei Ge, Ji-Yan Chen, Jie Quan, Seung-Whan Lee, Hsien-Li Kao, Etsuo Tsuchikane
Although the hybrid chronic total occlusion (CTO) algorithm had many excellent recommendations, there has been infrequent adoption in the Asia Pacific region. The Asia Pacific CTO club propose an algorithm for case selection based on the Japan-CTO score and a new CTO algorithm, which is applicable globally. This algorithm allows for differing skill sets and equipment availability and contains practical teaching for CTO percutaneous coronary intervention. Similar to the hybrid algorithm there are 3 main questions that determine whether the primary approach is antegrade or retrograde: 1) is there proximal cap ambiguity; 2) is the distal vessel of poor quality; and 3) are there interventional collaterals present...
November 13, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29119993/a-study-of-the-reactivity-of-s-vi-f-containing-warheads-with-nucleophilic-amino-acid-side-chains-under-physiological-conditions
#19
H Mukherjee, J Debreczeni, J Breed, S Tentarelli, B Aquila, J E Dowling, A Whitty, N P Grimster
Sulfonyl fluorides (SFs) have recently emerged as a promising warhead for the targeted covalent modification of proteins. Despite numerous examples of the successful deployment of SFs as covalent probe compounds, a detailed exploration of the factors influencing the stability and reactivity of SFs has not yet appeared. In this work we present an extensive study on the influence of steric and electronic factors on the reactivity and stability of the SF and related S(VI)-F groups. While SFs react rapidly with N-acetylcysteine, the resulting adducts were found to be unstable, rendering SFs inappropriate for the durable covalent inhibition of cysteine residues...
November 9, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29119075/the-classification-of-long-bone-osteomyelitis-a-systemic-review-of-the-literature
#20
REVIEW
Andrew J Hotchen, Martin A McNally, Parham Sendi
Background: Osteomyelitis is a complex disease. Treatment involves a combination of bone resection, antimicrobials and soft-tissue coverage. There is a difficulty in unifying a classification system for long bone osteomyelitis that is generally accepted. Objectives: In this systematic review, we aim to investigate the classification systems for long bone osteomyelitis that have been presented within the literature. By doing this, we hope to elucidate the important variables that are required when classifying osteomyelitis...
2017: Journal of bone and joint infection
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