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https://www.readbyqxmd.com/read/29773300/neoadjuvant-chemotherapy-is-associated-with-more-anemia-and-perioperative-blood-transfusions-than-primary-debulking-surgery-in-women-with-advanced-stage-ovarian-cancer
#1
Andrea O'Shea, Kevin McCool, Ross Harrison, Emmanuel Sampene, Joseph Connor, Lisa Barroilhet
OBJECTIVE: The purpose of this case-controlled study was to determine the prevalence of anemia and incidence of perioperative blood transfusions in patients undergoing treatment for advanced ovarian cancer with neoadjuvant chemotherapy (NACT) or primary debulking surgery (PDS). METHODS: We performed a single institution review of patients diagnosed with stage IIIB-IVB epithelial ovarian cancer between 2010 and 2013 undergoing either NACT or PDS. Anemia was defined as a hemoglobin (Hgb) concentration of ≤11...
May 15, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29772782/an-energy-balanced-and-lifetime-extended-routing-protocol-for-underwater-sensor-networks
#2
Hao Wang, Shilian Wang, Eryang Zhang, Luxi Lu
Energy limitation is an adverse problem in designing routing protocols for underwater sensor networks (UWSNs). To prolong the network lifetime with limited battery power, an energy balanced and efficient routing protocol, called energy balanced and lifetime extended routing protocol (EBLE), is proposed in this paper. The proposed EBLE not only balances traffic loads according to the residual energy, but also optimizes data transmissions by selecting low-cost paths. Two phases are operated in the EBLE data transmission process: (1) candidate forwarding set selection phase and (2) data transmission phase...
May 17, 2018: Sensors
https://www.readbyqxmd.com/read/29764843/poorly-cytotoxic-terminally-differentiated-cd56-neg-cd16-pos-nk-cells-accumulate-in-kenyan-children-with-burkitt-lymphomas
#3
Catherine S Forconi, Cormac P Cosgrove, Pryia Saikumar-Lakshmi, Christina E Nixon, Joslyn Foley, John Michael Ong'echa, Juliana A Otieno, Galit Alter, Christian Münz, Ann M Moormann
Natural killer (NK) cells are critical for restricting viral infections and mediating tumor immunosurveillance. Epstein-Barr virus (EBV) and Plasmodium falciparum malaria are known risk factors for endemic Burkitt lymphoma (eBL), the most common childhood cancer in equatorial Africa. To date, the composition and function of NK cells have not been evaluated in eBL etiology or pathogenesis. Therefore, using multiparameter flow cytometry and in vitro killing assays, we compared NK cells from healthy children and children diagnosed with eBL in Kenya...
May 22, 2018: Blood Advances
https://www.readbyqxmd.com/read/29759510/predicting-morbidity-after-robotic-partial-nephrectomy-the-effect-of-tumor-environment-and-patient-related-factors
#4
Zine-Eddine Khene, Benoit Peyronnet, Neil J Kocher, Haley Robyak, Corentin Robert, Benjamin Pradere, Emmanuel Oger, Solène-Florence Kammerer-Jacquet, Grégory Verhoest, Nathalie Rioux-Leclercq, Romain Mathieu, Jay D Raman, Karim Bensalah
PURPOSE: To investigate the effect of tumor and nontumor related parameters on perioperative outcomes of robotic partial nephrectomy (RPN). PATIENTS AND METHODS: Patients who underwent RPN for a localized renal tumor at 2 institutions between June 2010 and November 2016 were reviewed. RENAL and Mayo adhesive probability (MAP) scores were calculated and information on comorbid conditions including ASA score, performance status, Charlson's comorbidity index (CCI), and history of cardiovascular disease was collected...
May 11, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29758441/does-enquiry-based-learning-ebl-impact-on-clinical-practice-a-qualitative-exploration-of-midwifery-graduates-perceptions
#5
Kathleen Nallen, Dale Spence, Sam Porter
OBJECTIVE: To elicit perceptions of midwifery graduates regarding the impact of Enquiry Based Learning (EBL) on their clinical practice. DESIGN: A qualitative approach utilising semi-structured interviews and content analysis. SETTING: A midwifery education provider in the Republic of Ireland. PARTICIPANTS: Purposive sampling was employed to recruit fourteen midwifery graduates, from a total of twenty eight, from two cohorts who had successfully completed a Higher Diploma in Midwifery programme...
April 21, 2018: Midwifery
https://www.readbyqxmd.com/read/29731267/prior-anterior-cruciate-ligament-reconstruction-effects-on-future-total-knee-arthroplasty
#6
Alexander C M Chong, Brandon T Fisher, Lisa N MacFadden, Bruce E Piatt
BACKGROUND: The impact of prior anterior cruciate ligament (ACL) reconstruction on total knee arthroplasty (TKA) has rarely been studied. The objective of this study was to compare intraoperative characteristics in patients who underwent TKA with pre-existing hardware from prior ACL reconstruction with a matched cohort control group. METHODS: A retrospective study of patients who had undergone primary TKA with pre-existing hardware from prior ACL reconstruction was performed from June 2012 through June 2017...
April 19, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29730203/impact-of-host-factors-on-robotic-partial-nephrectomy-outcomes-comprehensive-systematic-review-and-meta-analysis
#7
REVIEW
Giovanni Cacciamani, Tania S Gill, Luis Medina, Akbar Ashrafi, Matthew Winter, Renè Sotelo, Walter Artibani, Inderbir Gill
PURPOSE: Host factors (tumor size/complexity, patient comorbidities) impact outcomes of robotic partial nephrectomy (RPN). We report a comprehensive systematic review and meta-analysis to critically evaluate impact of host factors on operative, peri-operative, functional, oncological and survival outcomes of RPN. MATERIALS & METHODS: All full-text English-language publications on RPN comparing host factors were evaluated. We followed Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement and Agency for Healthcare Research and Quality (AHRQ) guidelines to evaluate Pubmed®, Scopus® and Web of Science® (01/01/2000-31/06/2017)...
May 3, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29725852/three-dimensional-evaluation-of-the-posterior-airway-space-differences-in-computed-tomography-and-cone-beam-computed-tomography
#8
Nassim Ayoub, Philipp Eble, Kristian Kniha, Florian Peters, Stephan Christian Möhlhenrich, Evgeny Goloborodko, Frank Hölzle, Ali Modabber
OBJECTIVES: Obstructive sleep apnea syndrome (OSAS) becomes increasingly important. For diagnosis and surgery, computed tomography (CT), and cone beam computed tomography (CB-CT) are used equally, although in most of cases, patient positioning differs between supine positioning (CT) and upright seating positioning (CB-CT). We measured volumetric and anatomical changes in the posterior airway space (PAS) between upright and supine positioning in a three-dimensional set up. MATERIALS AND METHODS: Coherent CT and CB-CT scans of 55 patients were included in the study...
May 3, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29718160/safety-and-feasibility-of-robotic-assisted-ivor-lewis-esophagectomy
#9
K Meredith, J Huston, O Andacoglu, R Shridhar
Esophagectomy is associated with substantial morbidity. Robotic surgery allows complex resections to be performed with potential benefits over conventional techniques. We applied this technology to transthoracic esophagectomy to assess safety, feasibility, and reliability of this technology. A retrospective cohort study of all patients undergoing robotic-assisted Ivor-Lewis esophagectomy (RAIL) from 2009 to 2014 was conducted. Clinicopathologic factors and surgical outcomes were recorded and compared. All statistical tests were two-sided and a P-value of <0...
May 1, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29705337/cost-effectiveness-of-circumferential-fusion-for-lumbar-spondylolisthesis-propensity-matched-comparison-of-transforaminal-lumbar-interbody-fusion-versus-anterior-posterior-fusion
#10
Ehsan Jazini, Jeffrey L Gum, Steven D Glassman, Charles H Crawford, Mladen Djurasovic, R Kirk Owens, John R Dimar, Katlyn E McGraw, Leah Y Carreon
BACKGROUND CONTEXT: Transforaminal Lumbar Interbody Fusion (TLIF) and dual approach antero-posterior (AP) are common techniques to achieve circumferential fusion for lumbar spondylolisthesis. It is unclear which approach is more cost-effective. PURPOSE: Our goal is to determine the incremental cost-effectiveness ratio (ICER) by calculating the cost per quality-adjusted life year (QALY) for each approach. STUDY DESIGN/SETTING: Propensity matched cost-effectiveness comparison...
April 26, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29704203/safety-and-efficacy-of-synchronous-robotic-surgery-for-colorectal-cancer-with-liver-metastases
#11
REVIEW
Rozana H Dwyer, Matthew J Scheidt, J Stephen Marshall, Steven S Tsoraides
Timing of resection and treatment of colorectal cancer (CRC) with liver metastases varies based on patient characteristics and center protocols. Concerns of increased morbidity and mortality (M&M) related to anesthetic time and blood loss have limited widespread adaptation of synchronous colorectal and liver resections. Furthermore, technical challenges have made minimally invasive synchronous resections less common. We present our series of synchronous robotic surgery for CRC with liver metastases. Retrospective review of prospectively collected data of patients with stage IV CRC with liver metastases treated at a tertiary center from February 2013 to June 2014...
April 27, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29702313/comparison-of-complications-and-surgical-outcomes-of-adolescent-idiopathic-scoliosis-between-junior-attending-surgeons-and-senior-attending-surgeons
#12
Jun Qiao, Liangyan Xiao, Leilei Xu, Benlong Shi, Bangping Qian, Zezhang Zhu, Yong Qiu
BACKGROUND: To our knowledge, few studies have compared complications and surgical outcomes of adolescent idiopathic scoliosis between junior attending surgeons and senior attending surgeons. OBJECTIVES: To compare surgical strategies, complications and outcomes of posterior corrective surgery for AIS between junior attending surgeons and senior attending surgeons. METHODS: According to experience level of operation surgeons, the patients were assigned to two groups...
April 24, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29699956/outcomes-of-robotic-laparoscopic-and-open-hysterectomy-for-benign-conditions-in-obese-patients
#13
Mostafa A Borahay, Ömer Lütfi Tapısız, İbrahim Alanbay, Gökhan Sami Kılıç
OBJECTIVE: To compare outcomes of robotic assisted (RAH), total laparoscopic (LH) and total abdominal (TAH) hysterectomy for benign conditions in obese patients. MATERIAL AND METHODS: Retrospective cohort (Class II-2) analysis. All obese patients who underwent RAH, LH or TAH for benign conditions by a single surgeon at the University of Texas Medical Branch between January 2009 and December 2011 were identified and their charts reviewed. Patients' characteristics, operative data and post-operative outcomes were collected and statistically analyzed...
April 27, 2018: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/29695020/significant-hypo-responsiveness-to-gpvi-and-clec-2-agonists-in-pre-term-and-full-term-neonatal-platelets-and-following-immune-thrombocytopenia
#14
Alexander T Hardy, Verónica Palma-Barqueros, Stephanie K Watson, Jean-Daniel Malcor, Johannes A Eble, Elizabeth E Gardiner, José E Blanco, Rafael Guijarro-Campillo, Juan L Delgado, María L Lozano, Raúl Teruel-Montoya, Vicente Vicente, Steve P Watson, José Rivera, Francisca Ferrer-Marín
Neonatal platelets are hypo-reactive to the tyrosine kinase-linked receptor agonist collagen. Here, we have investigated whether the hypo-responsiveness is related to altered levels of glycoprotein VI (GPVI) and integrin α2β1, or to defects in downstream signalling events by comparison to platelet activation by C-type lectin-like receptor 2 (CLEC-2). GPVI and CLEC-2 activate a Src- and Syk-dependent signalling pathway upstream of phospholipase C (PLC) γ2. Phosphorylation of a conserved YxxL sequence known as a (hemi) immunotyrosine-based-activation-motif (ITAM) in both receptors is critical for Syk activation...
April 25, 2018: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29693213/nearly-efficiency-droop-free-algan-based-ultraviolet-light-emitting-diodes-with-a-specifically-designed-superlattice-p-type-electron-blocking-layer-for-high-mg-doping-efficiency
#15
Zi-Hui Zhang, Sung-Wen Huang Chen, Chunshuang Chu, Kangkai Tian, Mengqian Fang, Yonghui Zhang, Wengang Bi, Hao-Chung Kuo
This work reports a nearly efficiency-droop-free AlGaN-based deep ultraviolet light-emitting diode (DUV LED) emitting in the peak wavelength of 270 nm. The DUV LED utilizes a specifically designed superlattice p-type electron blocking layer (p-EBL). The superlattice p-EBL enables a high hole concentration in the p-EBL which correspondingly increases the hole injection efficiency into the multiple quantum wells (MQWs). The enhanced hole concentration within the MQW region can more efficiently recombine with electrons in the way of favoring the radiative recombination, leading to a reduced electron leakage current level...
April 24, 2018: Nanoscale Research Letters
https://www.readbyqxmd.com/read/29686594/analysis-of-the-risk-factors-associated-with-prolonged-intubation-or-reintubation-after-anterior-cervical-spine-surgery
#16
Moinay Kim, Seung Chul Rhim, Sung Woo Roh, Sang Ryong Jeon
Background: Standardized postoperative airway management is essential for patients undergoing anterior cervical spine surgery (ACSS). The paucity of clinical series evaluating these airway complications after ACSS has been resulted in a significant limitation in statistical analyses. Methods: A retrospective cohort study was performed regarding airway distress (intubation for more than 24 hours or unplanned reintubation within 7 days of operation) developed after ACSS...
April 23, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29685680/effects-of-salicylic-acid-epi-brassinolide-and-calcium-on-stress-alleviation-and-cd-accumulation-in-tomato-plants
#17
JunKang Guo, Ran Zhou, XinHao Ren, HongLei Jia, Li Hua, HuiHui Xu, Xin Lv, Jin Zhao, Ting Wei
Salicylic acid (SA), Epi-brassinolide (EBL) and calcium (Ca) play crucial roles in plant development and mediate plant response to biotic and abiotic stress. This study was aimed to investigate the possible mediatory role of SA, EBL, Ca or their combination in protecting tomato plants from cadmium (Cd) toxicity. According to the results, Cd stress resulted in a significant reduction of plant dry mass, photosynthetic pigment content as well as photosynthetic rate. Exogenous application of SA decreased the malondialdehyde (MDA) level by 39...
August 15, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29673673/the-application-of-uterine-wall-local-resection-and-reconstruction-to-preserve-the-uterus-for-the-management-of-morbidly-adherent-placenta-case-series
#18
Xianlan Zhao, Ya Tao, Yingying Du, Lei Zhao, Cai Liu, Yan Zhou, Peng Wei
OBJECTIVE: We aimed to evaluate our experience with the application of uterine wall local resection and reconstruction to preserve the uterus in patients with morbidly adherent placenta. MATERIALS AND METHODS: In a retrospective study, data from patients with morbidly adherent placenta who delivered by cesarean section between January 1, 2013 and May 31, 2016 were analyzed. Prophylactic abdominal aorta balloon occlusion and tourniquet were used to prevent massive hemorrhage in all 62 cases, followed by uterine wall local resection and reconstruction to preserve the uterus...
April 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29671905/oxygen-uptake-and-net-flux-of-metabolites-by-splanchnic-tissues-of-sheep-in-response-to-short-term-mesenteric-infusion-of-nitrogenous-compounds
#19
S Stefanello, M P Mezzomo, D Zeni, R C Ebling, A V Soares, G V Kozloski
This study was conducted in an attempt to quantify the impact of N load on splanchnic tissues metabolism of sheep. The trial was conducted with four male sheep (45 ± 2.5 kg body weight (BW)) surgically implanted with chronic indwelling catheters into the portal, hepatic and mesenteric veins. Blood flow and metabolic flux through portal-drained viscera (PDV), liver and total splanchnic tissues (ST) were measured daily following a 4 × 4 Latin Square experimental design, where sheep were continually infused into the mesenteric vein with a physiological saline (0...
April 19, 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29667818/balancing-the-electron-and-hole-transfer-for-efficient-quantum-dot-light-emitting-diodes-by-employing-a-versatile-organic-electron-blocking-layer
#20
Xiao Jin, Chun Chang, Weifeng Zhao, Shujuan Huang, Xiaobing Gu, Qin Zhang, Feng Li, Yubao Zhang, Qinghua Li
The electron blocking layer (EBL) is important to balance the charge carrier transfer and achieve highly efficient quantum dot light-emitting diodes (QLEDs). Here we report the utilization of a soluble tert-butyldimethylsilyl chloride-modified poly(p-phenylene benzobisoxazole) (TBS-PBO) as an EBL for simultaneous good charge carrier transfer balance while maintaining high current density. We show that the versatile TBS-PBO blocks excess electron injection into the QDs, thus leading to better charge carrier transfer balance...
April 18, 2018: ACS Applied Materials & Interfaces
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