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https://www.readbyqxmd.com/read/28421545/the-association-between-the-time-from-oxytocin-cessation-during-labour-to-cesarean-delivery-and-postpartum-blood-loss-a-retrospective-cohort-study
#1
Gary Tran, Marcelo Kanczuk, Mrinalini Balki
PURPOSE: Prolonged exposure to oxytocin during augmentation of labour is associated with uterine atony and an increased risk of postpartum hemorrhage (PPH) due to oxytocin receptor desensitization. Cessation of oxytocin infusion during labour may facilitate recovery of oxytocin receptor function, which then helps to restore myometrial contractility and decrease postpartum blood loss. We examined the association between oxytocin recovery interval, i.e., the time from discontinuing oxytocin to Cesarean delivery (CD) for labour arrest, and blood loss...
April 18, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/28418673/aberration-corrected-electron-beam-lithography-at-the-one-nanometer-length-scale
#2
Vitor Riseti Manfrinato, Aaron Stein, Lihua Zhang, Chang-Yong Nam, Kevin G Yager, Eric A Stach, Charles T Black
Patterning materials efficiently at the smallest length scales is a longstanding challenge in nanotechnology. Electron-beam lithography (EBL) is the primary method for patterning arbitrary features, but EBL has not reliably provided sub-4 nanometer patterns. The few competing techniques that have achieved this resolution are orders of magnitude slower than EBL. In this work, we employed an aberration-corrected scanning transmission electron microscope for lithography to achieve unprecedented resolution. Here we show aberration-corrected EBL at the one nanometer length scale using poly(methyl methacrylate) (PMMA), and have produced both the smallest isolated feature in any conventional resist (1...
April 18, 2017: Nano Letters
https://www.readbyqxmd.com/read/28414021/elliptical-broken-line-method-for-calculating-capillary-density-in-nailfold-capillaroscopy-proposal-and-evaluation
#3
Abdolamir Karbalaie, Farhad Abtahi, Alimohammad Fatemi, Mahnaz Etehadtavakol, Zahra Emrani, Björn-Erik Erlandsson
Nailfold capillaroscopy is a practical method for identifying and obtaining morphological changes in capillaries which might reveal relevant information about diseases and health. Capillaroscopy is harmless, and seems simple and repeatable. However, there is lack of established guidelines and instructions for acquisition as well as the interpretation of the obtained images; which might lead to various ambiguities. In addition, assessment and interpretation of the acquired images are very subjective. In an attempt to overcome some of these problems, in this study a new modified technique for assessment of nailfold capillary density is introduced...
April 14, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28412564/outcomes-of-patients-with-syringomyelia-undergoing-spine-deformity-surgery-do-large-syrinxes-behave-differently-than-small
#4
Amer F Samdani, Steven W Hwang, Anuj Singla, James T Bennett, Robert J Ames, Jeff S Kimball
BACKGROUND CONTEXT: A paucity of data exists studying outcomes of patients with syringomyelia undergoing spinal deformity correction. The literature does not stratify patients by syrinx size, which is likely a major contributor to outcomes. PURPOSE: To compare differences in outcomes between patients with large (≥ 4mm) and small syrinxes (< 4mm) undergoing spinal deformity correction. DESIGN: Retrospective review PATIENT SAMPLE: 28 patients (11 with large syrinx [LS, ≥ 4mm] and 17 with small syrinx [SS, < 4mm])...
April 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28409866/rh5-basigin-interaction-induces-changes-in-the-cytoskeleton-of-the-host-rbc
#5
Yaw Aniweh, Xiaohong Gao, Piliang Hao, Wei Meng, Soak Kuan Lai, Karthigayan Gunalan, Trang T Chu, Ameya Sinha, Julien Lescar, Rajesh Chandramohanadas, Hoi Yeung Li, Siu Kwan Sze, Peter R Preiser
The successful invasion of Plasmodium is an essential step in their life cycle. The parasite reticulocyte-binding protein homologues (RHs) and erythrocyte-binding like proteins (EBLs) are two families involved in the invasion leading to merozoite-RBC junction formation. Ca(2+) signaling has been shown to play a critical role in the invasion. RHs have been linked to Ca(2+) signaling which triggers the EBLs release ahead of junction formation, consistent with RHs performing an initial sensing function in identifying suitable RBCs...
April 13, 2017: Cellular Microbiology
https://www.readbyqxmd.com/read/28400759/human-and-epstein-barr-virus-mirna-profiling-as-predictive-biomarkers-for-endemic-burkitt-lymphoma
#6
Cliff I Oduor, Mercedeh Movassagh, Yasin Kaymaz, Kiprotich Chelimo, Juliana Otieno, John M Ong'echa, Ann M Moormann, Jeffrey A Bailey
Endemic Burkitt lymphoma (eBL) is an aggressive B cell lymphoma and is associated with Epstein-Barr virus (EBV) and Plasmodium falciparum malaria co-infections. Central to BL oncogenesis is the over-expression of the MYC proto-oncogene which is caused by a translocation of an Ig enhancer in approximation to the myc gene. While whole genome/transcriptome sequencing methods have been used to define driver mutations and transcriptional dysregulation, microRNA (miRNA) dysregulation and differential expression has yet to be fully characterized...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28398101/robot-assisted-pyeloplasty-and-pyelolithotomy-in-patients-with-ureteropelvic-junction-stenosis
#7
Pernille Hammershøj Jensen, Kasper Drimer Berg, Nessn H Azawi
OBJECTIVE: Approximately one in five patients with ureteropelvic junction stenosis (UPJS) also present with renal or ureteral stones. For patients with UPJS, the European Association of Urology guidelines currently recommend that robot-assisted pyeloplasty (RAP) and pyelolithotomy are performed as two separate procedures. The aim of the present study was to evaluate the feasibility and safety of RAP with concomitant pyelolithotomy (RAP + P) in patients diagnosed with UPJS and renal stones...
April 11, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28396208/efficacy-of-a-high-potency-o1-manisa-foot-and-mouth-disease-vaccine-in-cattle-against-heterologous-challenge-with-a-field-virus-from-the-o-me-sa-ind-2001-lineage-collected-in-north-africa
#8
Emma Fishbourne, Anna B Ludi, Ginette Wilsden, Pip Hamblin, Bob Statham, Abdelghani Bin-Tarif, Emiliana Brocchi, Santina Grazioli, Aldo Dekker, Phaedra Eblé, Donald P King
Outbreaks of foot-and-mouth disease (FMD) in North Africa (2013) and the Gulf States (2013) of the Middle East have been caused by a FMD viral lineage (O/ME-SA/Ind-2001) that was before 2013 restricted to the Indian Sub-continent. This study was undertaken to assess the in vivo efficacy of a FMD virus emergency vaccine type O1 Manisa against heterologous challenge with a representative field virus (O/ALG/3/2014) from this emerging lineage. This widely available vaccine was selected since in vitro vaccine-matching results gave inconclusive results as to whether or not it would be protective...
May 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28389913/real-time-evaluation-of-an-image-analysis-system-for-monitoring-surgical-hemoglobin-loss
#9
Gerhardt Konig, Jonathan H Waters, Mazyar Javidroozi, Bridget Philip, Vicki Ting, Gaurav Abbi, Eric Hsieh, Griffeth Tully, Gregg Adams
Monitoring blood loss is important for management of surgical patients. This study reviews a device (Triton) that uses computer analysis of a photograph to estimate hemoglobin (Hb) mass present on surgical sponges. The device essentially does what a clinician does when trying to make a visual estimation of blood loss by looking at a sponge, albeit with less subjective variation. The performance of the Triton system is reported upon in during real-time use in surgical procedures. The cumulative Hb losses estimated using the Triton system for 50 enrolled patients were compared with reference Hb measurements during the first quarter, half, three-quarters and full duration of the surgery...
April 7, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28370305/teaching-mid-urethral-sling-surgery-to-residents-impact-on-operative-time-and-postoperative-outcomes
#10
Ali-Reza Sharif-Afshar, Lauren N Wood, Catherine Bresee, Colby P Souders, Bruno S Gross, Eugene Shkolyar, Jennifer T Anger, Karyn S Eilber
AIMS: The purpose of this study was to determine the impact of resident teaching on outcomes of mid-urethral sling surgery. METHODS: A retrospective review of female patients who underwent an outpatient transobturator (TOT) synthetic mid-urethral sling procedure with and without concomitant prolapse repair by two surgeons (JA, KE) in a tertiary female pelvic medicine practice was performed. Total procedure time (TPT = time from incision to closure including sling placement and any prolapse procedure), estimated blood loss (EBL), and postoperative complications including urinary retention, mesh exposure, reoperation, vaginal bleeding, and leg pain were compared between cases with and without the presence of a resident...
March 31, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28366703/en-bloc-stapling-of-the-renal-hilum-during-laparoscopic-nephrectomy-a-double-institutional-analysis-of-safety-and-efficacy
#11
Benjamin A Sherer, Alexander K Chow, Matthew J Newsome, Christopher L Coogan, Sandip M Prasad, Kalyan C Latchamsetty
OBJECTIVE: To explore the safety and efficacy of en-bloc stapling of the renal hilum (EBSH) during laparoscopic nephrectomy (LNx) in a large double institution cohort with an extended follow-up period. MATERIALS AND METHODS: We performed a retrospective review of patients undergoing LNx with EBSH between 2008 and 2014 at two academic medical centers. Data analyzed included tumor size, tumor pathology, operative time, estimated blood loss (EBL), and perioperative or postoperative complications...
March 30, 2017: Urology
https://www.readbyqxmd.com/read/28366307/early-extubation-is-associated-with-reduced-length-of-stay-and-improved-outcomes-after-elective-aortic-surgery-in-the-vascular-quality-initiative
#12
Ramoncito A David, Benjamin S Brooke, Kristine T Hanson, Philip P Goodney, Elizabeth A Genovese, Donald T Baril, Peter Gloviczki, Randall R DeMartino
OBJECTIVE: Timing of extubation after open aortic procedures varies across hospitals. This study was designed to examine extubation timing and determine its effect on length of stay (LOS) and respiratory complications after elective open aortic surgery. METHODS: We studied extubation timing for 7171 patients undergoing elective open abdominal aortic aneurysm repair (2687 [37.5%]) or suprainguinal bypass for aortoiliac occlusive disease (4484 [62.5%]) from October 2010 to April 2015 in hospitals participating in the Vascular Quality Initiative (VQI)...
March 30, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28364335/neurological-complications-of-thoracic-posterior-vertebral-column-resection-for-severe-congenital-spinal-deformities
#13
Bo-Bo Zhang, Tao Zhang, Hui-Ren Tao, Tai-Lin Wu, Chun-Guang Duan, Wei-Zhou Yang, Tao Li, Feng Li, Ming Liu, Wen-Rui Ma, Wei Su
PURPOSE: The risk of neurological injury during vertebral column resection is high. In this study, we investigated the incidence and risk factors for neurological complications when treating spinal deformities by thoracic posterior vertebral column resection (PVCR). METHODS: Between 2008 and 2013, there were 62 consecutive patients (34 female patients and 28 male; the mean age: 16.3 years, range 6-46 years) treated with thoracic PVCR. We retrospectively reviewed the clinical records to obtain demographic and radiographic data, operative time, estimated blood loss (EBL, the ratio between circulating and lost blood), bleeding volume (the lost blood), number of vertebrae fused, number of vertebrae resected, usage of titanium mesh cage, and intraoperative neuromonitoring data...
March 31, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28364212/parenchymal-sparing-versus-anatomic-liver-resection-for-colorectal-liver-metastases-a-systematic-review
#14
Dimitrios Moris, Sean Ronnekleiv-Kelly, Amir A Rahnemai-Azar, Evangelos Felekouras, Mary Dillhoff, Carl Schmidt, Timothy M Pawlik
INTRODUCTION: Colorectal liver metastases develop in 50% of patients diagnosed with colorectal cancer. Surgical resection for colorectal liver metastasis typically involves either anatomical resection (AR) or parenchymal-sparing hepatectomy (PSH). The objective of the current study was to analyze data on parenchymal versus non-parenchymal-sparing hepatic resections for CLM. METHODS: A systematic review of the literature regarding parenchymal-sparing hepatectomy was performed...
March 31, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28362240/microvascularization-of-grade-i-meningiomas-effect-on-tumor-volume-blood-loss-and-patient-outcome
#15
Michael Karsy, Brian Burnett, Antonio Di Ieva, Michael D Cusimano, Randy L Jensen
OBJECTIVE Quantitative assessment of tumor microvascularity has the potential to improve prognostication, advance understanding of tumor biology, and help narrow potential molecular therapies. While the role of tumor microvascularity has been widely studied in meningiomas, this study examines both the role of automated measurements and the impact on surgical outcome. METHODS Two hundred seven patients with Grade I meningiomas underwent surgery between 1996 and 2011. Tissue samples from each patient were retrospectively evaluated for histopathological measures of microvascularity, including staining for von Willebrand factor (vWF), CD31, CD105, hypoxia-inducible factor 1 (HIF-1), vascular endothelial growth factor, glucose transporter 1, and carbonic anhydrase IX...
March 31, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28359921/increased-30-day-complication-rates-associated-with-laminectomy-in-874-adult-spine-deformity-patients-undergoing-elective-spinal-fusion-a-single-institutional-study
#16
Aladine A Elsamadicy, Owoicho Adogwa, Hunter Warwick, Amanda Sergesketter, Emily Lydon, Ronnie L Shammas, Ankit I Mehta, Raul A Vasquez, Joseph Cheng, Carlos A Bagley, Isaac O Karikari
BACKGROUND: Recent studies have reported that decompression with fusion leads to superior outcomes in the correction of spinal deformity. The aim of this study is to determine if there is a difference in intraoperative and 30-day postoperative complication rates in patients undergoing spinal fusion with and without decompression. METHODS: The medical records of 874 adult (≥18 years old) spine deformity patients undergoing elective spinal fusion at a major academic institution from 2005 to 2015 were reviewed...
March 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28352149/robot-assisted-partial-nephrectomy-for-t1b-tumors-strict-trifecta-outcomes
#17
Ilter Tufek, Panagiotis Mourmouris, Tunkut Doganca, Can Obek, Omer Burak Argun, Mustafa Bilal Tuna, Mehmet Selcuk Keskin, Ali Rıza Kural
BACKGROUND AND OBJECTIVES: "Trifecta" in partial nephrectomy consists of negative surgical margins, minimal renal function decrease and absence of complications. In the present article, our single-center robot-assisted partial nephrectomy (RAPN) experience in T1b renal masses is reported in terms of strict Trifecta outcomes. METHODS: This is a retrospective analysis of patients with a tumor diameter between 4 and 7 cm (stage T1b), who underwent RAPN by a single surgeon...
January 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28344570/tanycytes-as-regulators-of-seasonal-cycles-in-neuroendocrine-function
#18
REVIEW
Jo E Lewis, Francis J P Ebling
Annual cycles of physiology and behavior are highly prevalent in organisms inhabiting temperate and polar regions. Examples in mammals include changes in appetite and body fat composition, hibernation and torpor, growth of antlers, pelage and horns, and seasonal reproduction. The timing of these seasonal cycles reflects an interaction of changing environmental signals, such as daylength, and intrinsic rhythmic processes: circannual clocks. As neuroendocrine signals underlie these rhythmic processes, the focus of most mechanistic studies has been on neuronal systems in the hypothalamus...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28340062/exogenously-applied-24-epibrassinolide-ebl-ameliorates-detrimental-effects-of-salinity-by-reducing-k-efflux-via-depolarization-activated-k-channels
#19
Nazila Azhar, Nana Su, Lana Shabala, Sergey Shabala
This study has investigated mechanisms conferring beneficial effects of exogenous application of 24-epibrassinolides (EBL) on plant growth and performance under saline conditions. Barley seedlings treated with 0.25 mg l-1 EBL showed significant improvements in root hair length, shoot length, shoot fresh weight and relative water content when grown in the presence of 150 mM NaCl in the growth medium. In addition, EBL treatment significantly decreased the Na+ content in both shoots (by approximately 50%) and roots...
April 1, 2017: Plant & Cell Physiology
https://www.readbyqxmd.com/read/28337234/is-computerised-tomography-better-than-fibreoptic-gastroscopy-for-early-detection-of-gastric-varices
#20
Burak Suvak, Murat Kekilli, Yavuz Beyazıt, Sarper Okten, Alpaslan Tanoglu, Nurgul Sasmaz
INTRODUCTION: Video endoscopic diagnosis of gastric varices is particularly limited, owing to the deep submucosal or subserosal location of the varices and the normal appearance of the overlying mucosa. AIM: We present and emphasise the value of computerised tomography (CT) examination in the early detection of gastric varices (GVs). MATERIAL AND METHODS: In this retrospective study, a total of 216 consecutive patients with cirrhosis were evaluated at the Turkiye Yuksek Ihtisas Training and Research Hospital between September 2008 and March 2011...
2017: Przegla̜d Gastroenterologiczny
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