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https://www.readbyqxmd.com/read/28922687/comparison-of-perioperative-renal-and-oncologic-outcomes-in-robotic-assisted-versus-open-partial-nephrectomy
#1
Jo-Lynn Tan, Mark Frydenberg, Jeremy Grummet, Uri Hanegbi, Ross Snow, Sarah Mann, Kirobel Begashaw, Daniel Moon
BACKGROUND: To compare perioperative, renal and oncological outcomes after robotic-assisted partial nephrectomy (RAPN) versus open partial nephrectomy (OPN) for the treatment of renal tumours. METHODS: All partial nephrectomies performed at a Metropolitan Urology Centre between 2010 and 2016 were analysed. Baseline data was collected for patient demographics, tumour characteristics (tumour size, laterality and polarity, RENAL scores), and perioperative variables (e...
September 18, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28922304/estimated-blood-loss-during-vaginal-hysterectomy-and-adnexal-surgery-described-with-an-intraoperative-pictographic-tool
#2
Nancy C Nelson, Stuart A Ostby, Amy L Weaver, Michaela E McGree, John B Gebhart, Jamie N Bakkum-Gamez
OBJECTIVE: We describe a novel way to calculate estimated blood loss (EBL) using an intraoperative pictographic tool in gynecologic surgery. METHODS: A pictographic tool to estimate sponge saturation was developed to calculate EBL during surgery. A prospective cohort of women 18 years or older undergoing benign vaginal hysterectomy with planned adnexal surgery at Mayo Clinic were consented for use of the pictographic tool. Demographic, preoperative, intraoperative, and postoperative data were abstracted...
September 15, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28919610/open-door-laminoplasty-for-multilevel-cervical-spondylotic-myelopathy-and-ossification-of-the-posterior-longitudinal-ligament-opll-using-titanium-reconstruction-miniplate-and-screws
#3
M K Ahsan, M A Awwal, S I Khan, N Zaman, M H Haque, Z Zahangiri
To review outcome of 25 patients who underwent open-door cervical laminoplasty for multilevel cervical spondylotic myelopathy (MCSM) and ossification of the posterior longitudinal ligament (OPLL) using titanium reconstruction miniplate and screws. Records of 18 men and 7 women aged 35 to 78 (mean, 62.6) years were reviewed retrospectively from October 2009 and October 2014 at Bangabandhu Sheikh Mujib Medical University (BSMMU) and in our private settings, Dhaka, Bangladesh. Four patients had 5 levels (C3-C7), 21 patients had 4 levels (C3-C6) decompression and 3 patients (12%) performed foraminotomies...
July 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28919522/the-incidence-of-ischemic-colitis-after-repair-of-ruptured-abdominal-aortic-aneurysms-is-decreasing-in-the-endovascular-era
#4
S K Desikan, N Singh, S R Steele, N Tran, E Quiroga, P Danaher, B T Garland, B W Starnes
OBJECTIVE: Ischemic colitis (IC) is a well-described complication of ruptured abdominal aortic aneurysms (rAAA). The purpose of this study was to compare the incidence of IC in patients with rAAA undergoing open (OR) vs. endovascular aneurysm repair (EVAR) at a single institution. In addition, we analyzed the incidence of ischemic colitis pre- and post- implementation of a formal rupture AAA protocol (rEVAR protocol). METHODS: A retrospective analysis of prospectively collected data on all patients presenting with rAAA to our institution between Jan 2002 and Oct 2013 was performed...
September 14, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28918987/diagnosing-and-treating-enquiry-based-learning-fatigue-in-graduate-entry-nursing-students
#5
Gemma Stacey, Claire Wilson, Helen Reddy, Chris Palmer, James Henderson, Hannah Little, Heather Bull
The use of student directed study approaches such as Enquiry Based Learning (EBL) in the design and implementation of Graduate Entry Nursing Circular is well established. The rational relates to the maximisation of graduate attributes such as motivation to learn, the ability to identify, search and assimilate relevant literature and the desire to take ownership of the direction and pace of learning. Existing alongside this however, is the observation that students remain under confident in the application of knowledge to a clinical context and frustrated with learning approaches which do not appear directly related to improving their competence in this area...
September 9, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/28915307/the-use-of-bone-morphogenetic-protein-in-spinal-transforaminal-lumbar-interbody-fusion-our-experience
#6
Eduardo Colom-Beauchamp, David Beaton-Comulada, Julio A Rodriguez, José C Pérez-López, José Montañez-Huertas, Enrique Escobar-Medina, José Massanet-Vollrath
OBJECTIVE: Since its introduction and FDA approval, rhBMP-2 has been adopted by spine surgeons as a substitute for ICBG in numerous spinal fusion techniques. As broad clinical use increased, reports on potential complications associated with rhBMP-2 also increased. We provide our experience with TLIF using rhBMP-2 or ICBG in an entirely Hispanic population. METHODS: This was a 2-year retrospective study of 67 patients, with 26 in the rhBMP-2 group and 41 in the ICBG group, who underwent TLIF...
September 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/28903326/distinct-clinicopathological-features-in-metanephric-adenoma-harboring-braf-mutation
#7
Anna Caliò, John N Eble, Ondrej Hes, Guido Martignoni, Saul E Harari, Sean R Williamson, Matteo Brunelli, Adeboye O Osunkoya, Lisha Wang, Eva Comperat, Antonio Lopez-Beltran, Mingsheng Wang, Shaobo Zhang, Kendra L Curless, Kristin M Post, Hsim-Yee Chang, Claudio Luchini, Lee Ann Baldrige, Gregory T MacLennan, Rodolfo Montironi, David J Grignon, Liang Cheng
BRAF mutation recently has been reported in metanephric adenoma. We sought to determine the clinical and morphologic features of BRAF-mutated metanephric adenoma and to correlate BRAF mutation with BRAF V600E immunohistochemical staining results. A series of 48 metanephric adenomas and 15 epithelial-predominant nephroblastomas were analyzed for the occurrence of BRAF mutation (BRAF V600E/V600E complex, BRAF V600D, BRAF V600K and BRAF V600R) using the BRAF RGQ PCR kit (Qiagen). Immunohistochemistry was performed using monoclonal mouse antibodies against p16(INK4) and VE1 (Spring Bioscience), recognizing the BRAF V600E mutant protein...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28885286/predicting-perioperative-complications-in-adult-spinal-deformity-surgery-using-a-simple-sliding-scale
#8
Go Yoshida, Tomohiko Hasegawa, Yu Yamato, Sho Kobayashi, Shin Oe, Tomohiro Banno, Yuuki Mihara, Hideyuki Arima, Hiroki Ushirozako, Tatsuya Yasuda, Daisuke Togawa, Yukihiro Matsuyama
STUDY DESIGN: Retrospective database study OBJECTIVE.: To develop and validate a sliding scale for predicting perioperative complications associated with ASD surgery. SUMMARY OF BACKGROUND DATA: ASD surgery can have high perioperative complication rates, which is associated with increased morbidity and mortality. METHODS: Data on consecutive ASD patients undergoing posterior corrective surgery over a six-year interval were collected from a prospective database...
September 6, 2017: Spine
https://www.readbyqxmd.com/read/28881317/modulation-of-antioxidative-defense-expression-and-osmolyte-content-by-co-application-of-24-epibrassinolide-and-salicylic-acid-in-pb-exposed-indian-mustard-plants
#9
Sukhmeen Kaur Kohli, Neha Handa, Shagun Bali, Saroj Arora, Anket Sharma, Ravdeep Kaur, Renu Bhardwaj
The study focuses on potential of combined pre-soaking treatment of 24-Epibrassinolide (EBL) and Salicylic acid (SA) in alleviating Pb phytotoxicity in Brassica juncea L. plants. The seeds after treatment with combination of both the hormones were sown in mixture of soil, sand and manure (3:1:1) and were exposed to Pb concentrations (0.25mM, 0.50mM and 0.75mM). After 30 days of growth, the plants were harvested and processed, for quantification of various metabolites. It was found that pre-sowing of seeds in combination of EBL and SA, mitigated the adverse effects of metal stress by modulating antioxidative defense response and enhanced osmolyte contents...
September 4, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28879437/major-underestimation-and-overestimation-of-visual-blood-loss-during-cesarean-deliveries-can-they-be-predicted
#10
Ohad Gluck, Yossi Mizrachi, Michal Kovo, Michael Divon, Jacob Bar, Eran Weiner
PURPOSE: The surgeons' visual estimation is the most widely used method for estimating blood loss (BL) while performing cesarean deliveries (CDs). Major BL underestimation may adversely influence obstetric decision making, and result in delaying interventions. Major BL overestimation may result in unnecessary costly interventions. Therefore, we aimed to identify independent predictors for major BL underestimation and overestimation during CDs. METHODS: All CDs performed between 11/2008 and 6/2016, in a university-affiliated hospital, were reviewed for demographic and surgical data, including the surgeons' reported estimated BL (EBL)...
September 6, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28877162/correction-dramatic-and-concerted-conformational-changes-enable-rhodocetin-to-block-%C3%AE-2%C3%AE-1-integrin-selectively
#11
Johannes A Eble, Matthew McDougall, George L Orriss, Stephan Niland, Benjamin Johanningmeier, Gottfried Pohlentz, Markus Meier, Simone Karrasch, Maria Inacia Estevão-Costa, Augusto Martins Lima, Jörg Stetefeld
[This corrects the article DOI: 10.1371/journal.pbio.2001492.].
September 2017: PLoS Biology
https://www.readbyqxmd.com/read/28875952/role-of-r-e-n-a-l-nephrometry-score-in-laparoscopic-partial-nephrectomy
#12
Hai-Jiang Zhou, Yong Yan, Jian-Zhong Zhang, Li-Rong Liang, Shu-Bin Guo
Background: Preoperative anatomical scoring system is conducive to comparison between treatment options and evaluation of postoperative outcomes in patients with small renal tumors. This study aimed to evaluate the clinical application efficacy of the R.E.N.A.L. nephrometry score (RNS) in predicting perioperative outcomes in patients with renal tumor who underwent laparoscopic partial nephrectomy (LPN). Methods: The clinical data of 139 patients with renal tumors who underwent LPN between 2009 and 2015 were collected and analyzed...
September 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28873326/external-validation-and-comparisons-of-the-scoring-systems-for-predicting-percutaneous-nephrolithotomy-outcomes-a-single-center-experience-with-506-cases
#13
Serkan Yarimoglu, Ibrahim Halil Bozkurt, Ozgu Aydogdu, Tarik Yonguc, Bulent Gunlusoy, Tansu Degirmenci
BACKGROUND: To validate and compare the stone scoring systems (stone size [S], tract length [T], obstruction [O], number of involved calices [N], and essence or stone density [E] [S.T.O.N.E.], Guy's Stone Score [GSS], Clinical Research Office of the Endourological Society [CROES], and Seoul National University Renal Stone Complexity [S-ReSC]) used to predict postoperative stone-free status and complications after percutaneous nephrolithotomy (PCNL). METHODS: A total of 567 patients who underwent PCNL for renal stones between January 2012 and August 2015 were included in the recent retrospective study...
September 5, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28871986/quality-of-life-after-radiation-therapy-for-prostate-cancer-with-a-hydrogel-spacer-5-year-results
#14
Michael Pinkawa, Vanessa Berneking, Marsha Schlenter, Barbara Krenkel, Michael J Eble
PURPOSE: To evaluate quality of life changes up to 5 years after prostate cancer radiation therapy (RT) with a hydrogel spacer. METHODS AND MATERIALS: In the years 2010 to 2011, 114 patients received external beam radiation therapy to the prostate; 54 patients were selected for a hydrogel injection before the beginning of RT. Treatment was performed applying fractions of 2 Gy up to a total dose of 76 Gy (n=96) or 78 Gy (n=18, all with hydrogel). Patients were surveyed before RT; at the last day of RT; and a median time of 2 months, 17 months, and 63 months after RT using a validated questionnaire (Expanded Prostate Cancer Index Composite)...
October 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28865229/cytokine-profiles-of-dendritic-cells-dcs-during-infection-with-bovine-leukaemia-virus-blv
#15
E Iwan, M Szczotka, J Kocki
BLV is an agent of enzootic bovine leukaemia (EBL), an infectious disease affecting cattle worldwide. BLV infection has been associated with immune system disorders and discrepancies in the cytokine network. The significance of dendritic cells in the pathogenesis of BLV infection is largely unknown, but considering their fundamental role in immune response it may be crucial. DCs precursors were isolated with the use of immunomagnetic beads from BLV-infected and BLV-free cows. From these precursors cultures of monocyte derived dendritic cells (MoDCs) were generated with the use of a cytokine cocktail (IL-4 and GM-CSF)...
March 1, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28861728/off-clamp-robot-assisted-partial-nephrectomy-does-not-benefit-short-term-renal-function-a-matched-cohort-analysis
#16
Barrett G Anderson, Aaron M Potretzke, Kefu Du, Joel Vetter, R Sherburne Figenshau
In the interest of renal functional preservation, partial nephrectomy has supplanted radical nephrectomy as the preferred treatment for T1 renal masses. This procedure usually involves the induction of renal warm ischemia by clamping the hilar vessels prior to tumor excision. Performing robot-assisted partial nephrectomy (RAPN) "off-clamp" can theoretically prevent renal functional loss associated with warm ischemia. We describe our institutional experience and compare perioperative and renal functional outcomes using a propensity score matched cohort...
August 31, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28861080/isolation-of-single-domain-antibody-fragments-that-preferentially-detect-intact-146s-particles-of-foot-and-mouth-disease-virus-for-use-in-vaccine-quality-control
#17
Michiel M Harmsen, Julian Seago, Eva Perez, Bryan Charleston, Phaedra L Eblé, Aldo Dekker
Intact (146S) foot-and-mouth disease virus (FMDVs) can dissociate into specific (12S) viral capsid degradation products. FMD vaccines normally consist of inactivated virions. Vaccine quality is dependent on 146S virus particles rather than 12S particles. We earlier isolated two llama single-domain antibody fragments (VHHs) that specifically recognize 146S particles of FMDV strain O1 Manisa and shown their potential use in quality control of FMD vaccines during manufacturing. These 146S-specific VHHs were specific for particular O serotype strains and did not bind strains from other FMDV serotypes...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28857329/anesthetic-considerations-for-a-novel-anterior-surgical-approach-to-pediatric-scoliosis-correction
#18
Jonathan S Gal, Christopher J Curatolo, Jeron Zerillo, Bryan Hill, Baron Lonner, Laury A Cuddihy, M D Antonacci, Randal R Betz, Samuel DeMaria, Yury Khelemsky
BACKGROUND: Idiopathic scoliosis is a condition that may require surgical correction. Limitations of previous surgical modalities, however, created the need for novel methods of repair. One such technique, a newer form of anterolateral scoliosis correction, has shown considerable promise, which our center has had substantial experience performing. AIM: In this article, we present the case details of our first 105 patients for the purposes of describing the evolution and details of the anesthetic management and considerations for this procedure...
August 31, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28857124/accuracy-of-postpartum-haemorrhage-data-in-the-2011-victorian-perinatal-data-collection-results-of-a-validation-study
#19
Margaret Flood, Wendy Pollock, Susan J McDonald, Mary-Ann Davey
BACKGROUND: The postpartum haemorrhage (PPH) rate in Victoria in 2009 for women having their first birth, based on information reported to the Victorian Perinatal Data Collection (VPDC), was 23.6% (primiparas). Prior to 2009 PPH was collected via a tick box item on the perinatal form. Estimated blood loss (EBL) volume is now collected and it is from this item the PPH rate is calculated. Periodic assessment of data accuracy is essential to inform clinicians and others who rely on these data of their quality and limitations...
August 31, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28836105/surgical-and-pathological-outcomes-of-robotic-assisted-radical-cystectomy-for-bladder-cancer-in-the-community-setting
#20
E M DiLizia, F Sadeghi
Robotic-assisted radical cystectomy (RARC) with urinary diversion is commonly performed in community hospitals. While little data exist on RARC outcomes in this setting, community hospitals may improve access to care for bladder cancer patients. We conducted a retrospective review of 76 patients who underwent RARC between 2006 and 2016 by two robotic-trained surgeons in two local community hospitals. A total of 76 patients (60 males and 16 females; ages 46-89) underwent RARC with extended pelvic lymphadenectomy and urinary diversion (69 ileal conduits, 7 neobladders) for muscle-invasive bladder carcinoma (79%), recurrent high-grade carcinoma (17%), unresectable tumor (2%), or refractory gross hematuria from chemotherapy (2%)...
August 23, 2017: Journal of Robotic Surgery
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