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https://www.readbyqxmd.com/read/29162482/antimicrobial-activity-of-melaleuca-alternifolia-nanoparticles-in-polymicrobial-biofilm-in-situ
#1
Márcia Ebling de Souza, Dariane Jornada Clerici, Camila Marina Verdi, Gabriela Fleck, Priscilla Maciel Quatrin, Luana Ebling Spat, Pauline Cordenonsi Bonez, Camilla Fillippi Dos Santos, Raquel Pippi Antoniazzi, Fabrício Batistin Zanatta, André Gundel, Diego Stefani Teodoro Martinez, Rodrigo de Almeida Vaucher, Roberto Christ Vianna Santos
Microbial biofilms represent a challenge in the treatment of infections, due to the low efficacy of the antimicrobials. This study evaluated the antimicrobial effect of nanoparticles of Melaleuca alternifolia (TTO) in dental biofilm. Thirty-eight volunteers used an oral device in situ in situ including four bovine enamel specimens for 07 days. From the fifth day four solutions were applied randomly for each specimen: Physiological Saline Solution (0.85% NaCl) (C+), Chlorhexidine 0.12% (CHX), M. alternifolia oil 0...
November 18, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29161805/robot-assisted-radical-cystectomy-with-totally-intracorporeal-urinary-diversion-initial-single-surgeon-s-experience-after-a-modified-modular-training
#2
Angelo Porreca, Francesco Chessa, Daniele Romagnoli, Antonio Salvaggio, Angelo Cafarelli, Marco Borghesi, Lorenzo Bianchi, Matteo Dandrea, Daniele D'Agostino, Donato Dente, Emanuele Cappa, Peter Wiklund, Eugenio Brunocilla, Riccardo Schiavina
BACKGROUND: To report the perioperative and early functional outcomes of patients undergoing Robot-assisted radical cystectomy (RARC) with totally intracorporeal urinary diversion performed by a single surgeon after a modified modular training. METHODS: The surgeon (A.P.) attained a 30-days modified modular training at a referring Centre mentored by a worldwide-recognized robotic surgeon (P.W.). The training program consisted of: a) e-learning based on 10 hours of theoretical lessons made by the mentor; b) video-session concerning the different steps of the procedure, c) step-by-step in vivo modular training...
November 21, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29156134/organic-ice-resists
#3
William Tiddi, Anna Elsukova, Hoa Thanh Le, Pei Liu, Marco Beleggia, Anpan Han
Electron-beam lithography (EBL) is the backbone technology for patterning nanostructures and manufacturing nanodevices. It involves processing and handling synthetic resins in several steps, each requiring optimization and dedicated instrumentation in cleanroom environments. Here, we show that simple organic molecules, e.g. alcohols, condensed to form thin-films at low temperature demonstrate resist-like capabilities for EBL applications and beyond. The entire lithographic process takes place in a single instrument, and avoids exposing chemicals to the user and the need of cleanrooms...
November 20, 2017: Nano Letters
https://www.readbyqxmd.com/read/29141380/-the-analysis-of-anesthetic-management-for-renal-cell-carcinoma-with-associated-inferior-vena-cava-tumor-thrombus
#4
H Zeng, X Y Rong, Y Wang, X Y Guo
Objective: To explore the key points of anesthetic management for renal cell carcinoma combined with inferior vena cava (IVC) tumor thrombus. Methods: Twenty-seven cases of renal cell carcinoma with inferior vena cava (IVC) tumor thrombus underwent radical nephrectomy and inferior caval venous thrombectomy were reviewed retrospectively during January 2014 to January 2017 in our hospital.Analyzed data includs demographics, classification of tumor, perioperative anesthetic management and monitoring approaches, IVC clamping time , vital signs during cardiopulmonary bypass(CPB), estimated blood loss (EBL), usage of blood products, hospitalization time and ICU time , as well as postoperative outcomes...
November 14, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29140272/an-investigation-of-polyoxometalate-hybrid-materials-as-patternable-dielectrics-and-lithographic-resists
#5
Brandon Hardie, Mark Roll
Polyoxometalate (POM) hybrid materials have shown potential as spin-coatable, patternable dielectric thin-films and components for lithographic resists. In particular, the octamolybdate cluster has been shown to possess good spin-coating properties and the patterning capabilities of hybrid octamolybdate thin-films were explored using a combination of broadband UV and electron beam lithography (EBL) techiniques. Dielectric properties of these films were determined by ellipsometry, and octamolybdate clusters were subsequently investigated as negative resists in various blends for potential uses in next-generation photolithography, where contrast, sensitivity, and line edge roughness characteristics were determined...
November 15, 2017: Materials
https://www.readbyqxmd.com/read/29139337/do-people-with-severe-traumatic-brain-injury-benefit-from-making-errors-a-randomized-controlled-trial-of-error-based-and-errorless-learning
#6
Tamara Ownsworth, Jennifer Fleming, Robyn Tate, Elizabeth Beadle, Janelle Griffin, Melissa Kendall, Julia Schmidt, Amanda Lane-Brown, Mathilde Chevignard, David H K Shum
BACKGROUND: Errorless learning (ELL) and error-based learning (EBL) are commonly used approaches to rehabilitation for people with traumatic brain injury (TBI). However, it is unknown whether making errors is beneficial in the learning process to promote skills generalization after severe TBI. OBJECTIVE: To compare the efficacy of ELL and EBL for improving skills generalization, self-awareness, behavioral competency, and psychosocial functioning after severe TBI...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29137917/radiation-exposure-with-hybrid-image-guidance-based-minimally-invasive-transforaminal-lumbar-interbody-fusion
#7
Michael M Safaee, Taemin Oh, Murat Pekmezci, Aaron J Clark
The transforaminal lumbar interbody fusion (TLIF) is used for the treatment of back and leg pain secondary to spinal stenosis, degenerative disc disease, and spondylolisthesis. Minimally invasive surgery (MIS) is associated with less estimated blood loss (EBL), decreased length of stay, lower infection rates, and similar outcomes compared to the traditional TLIF. Fluoroscopy time has been reported with MIS-TLIF, but there are limited data on specific radiation dosages. We performed a retrospective analysis of a prospectively acquired cohort of patients undergoing MIS-TLIF...
November 11, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29132724/emerging-entities-in-renal-cell-neoplasia-thyroid-like-follicular-renal-cell-carcinoma-and-multifocal-oncocytoma-like-tumours-associated-with-oncocytosis
#8
REVIEW
John N Eble, Brett Delahunt
The list of accepted entities of renal cell neoplasia has burgeoned since the turn of the century through recognition of rare tumour types and the discovery of genetic mutations driving renal neoplasia syndromes. This growth has not finished and in this report we present examples of each of these types which were not included in the 2016 World Health Organization classification of renal neoplasia, but are candidates for inclusion in the next edition of the classification. Thyroid-like follicular renal cell carcinoma is a rare tumour type with a distinctive microscopic appearance resembling follicles of the thyroid gland...
November 10, 2017: Pathology
https://www.readbyqxmd.com/read/29132323/integrative-microrna-and-mrna-deep-sequencing-expression-profiling-in-endemic-burkitt-lymphoma
#9
Cliff I Oduor, Yasin Kaymaz, Kiprotich Chelimo, Juliana A Otieno, John Michael Ong'echa, Ann M Moormann, Jeffrey A Bailey
BACKGROUND: Burkitt lymphoma (BL) is characterized by overexpression of the c-myc oncogene, which in the vast majority of cases is a consequence of an IGH/MYC translocation. While myc is the seminal event, BL is a complex amalgam of genetic and epigenetic changes causing dysregulation of both coding and non-coding transcripts. Emerging evidence suggest that abnormal modulation of mRNA transcription via miRNAs might be a significant factor in lymphomagenesis. However, the alterations in these miRNAs and their correlations to their putative mRNA targets have not been extensively studied relative to normal germinal center (GC) B cells...
November 13, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29124406/selective-lateral-pelvic-lymph-node-dissection-a-comparative-study-of-the-robotic-versus-laparoscopic-approach
#10
Hye Jin Kim, Gyu-Seog Choi, Jun Seok Park, Soo Yeun Park, Hee Jae Lee, In Taek Woo, In Kyu Park
BACKGROUND: Lateral pelvic lymph node dissection (LPND) is a challenging procedure due to its technical difficulty and higher incidence of surgical morbidity. We compared short-term outcomes between laparoscopic and robotic LPND in patients with rectal cancer. METHODS: Between May 2006 and December 2014, prospectively collected data from consecutive patients undergoing robotic or laparoscopic total mesorectal excision (TME) with LPND were retrospectively compared...
November 9, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29123514/assessment-of-the-combined-effect-of-epstein-barr-virus-and-plasmodium-falciparum-infections-on-endemic-burkitt-lymphoma-using-a-multiplex-serological-approach
#11
Ruth Aguilar, Delphine Casabonne, Cristina O'Callaghan-Gordo, Marta Vidal, Joseph J Campo, Nora Mutalima, Evelina Angov, Sheetij Dutta, Deepak Gaur, Chetan E Chitnis, Virander Chauhan, Angelika Michel, Silvia de Sanjosé, Tim Waterboer, Manolis Kogevinas, Rob Newton, Carlota Dobaño
Epstein-Barr virus (EBV) is a necessary cause of endemic Burkitt lymphoma (eBL), while the role of Plasmodium falciparum in eBL remains uncertain. This study aimed to generate new hypotheses on the interplay between both infections in the development of eBL by investigating the IgG and IgM profiles against several EBV and P. falciparum antigens. Serum samples collected in a childhood study in Malawi (2005-2006) from 442 HIV-seronegative children (271 eBL cases and 171 controls) between 1.4 and 15 years old were tested by quantitative suspension array technology against a newly developed multiplex panel combining 4 EBV antigens [Z Epstein-Barr replication activator protein (ZEBRA), early antigen-diffuse component (EA-D), EBV nuclear antigen 1, and viral capsid antigen p18 subunit (VCA-p18)] and 15 P...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29120299/bovine-leukaemia-virus-genotypes-5-and-6-are-circulating-in-cattle-from-the-state-of-s%C3%A3-o-paulo-brazil
#12
Lilian Gregory, Natália Carrillo Gaeta, Jansen Araújo, Luciano Matsumiya Thomazelli, Ricardo Harakawa, Alice A Ikuno, Liria Hiromi Okuda, Eliana de Stefano, Edviges Maristela Pituco
PURPOSE: Enzootic bovine leucosis (EBL) is a silent disease caused by a retrovirus [bovine leukaemia virus (BLV)]. BLV is classified into almost 10 genotypes that are distributed in several countries. The present research aimed to describe two BLV gp51 env sequences of strains detected in the state of São Paulo, Brazil and perform a phylogenetic analysis to compare them to other BLV gp51 env sequences of strains around the world. METHODOLOGY: Two bovines from different herds were admitted to the Bovine and Small Ruminant Hospital, School of Veterinary Medicine and Animal Science, University of São Paulo, Brazil...
November 9, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29118521/a-proposal-of-an-effective-platelet-rich-plasma-protocol-for-the-treatment-of-androgenetic-alopecia
#13
Juan Ferrando, Sandra Cecilia García-García, Ana Cecilia González-de-Cossío, Lola Bou, Esperanza Navarra
Background: Platelet-rich plasma (PRP) has emerged as a promising treatment for androgenetic alopecia (AGA). In spite of the several studies previously reported, to date, a standardized protocol for PRP preparation and application, as well as a standard method for evaluating results has not been established. Aims: The aim of this study is to propose a standardized method for preparation and application of PRP for male AGA (MAGA) and female AGA (FAGA) and assess its safety and efficacy as a co-adjuvant therapy...
October 2017: International Journal of Trichology
https://www.readbyqxmd.com/read/29116967/validation-of-a-new-method-to-automatically-select-cases-with-intraoperative-red-blood-cell-transfusion-for-audit
#14
Franklin Dexter, Richard H Epstein, Johannes Ledolter, Susan M Dasovich, Jay H Herman, Joni M Maga, Eric S Schwenk
BACKGROUND: Hospitals review allogeneic red blood cell (RBC) transfusions for appropriateness. Audit criteria have been published that apply to 5 common procedures. We expanded on this work to study the management decision of selecting which cases involving transfusion of at least 1 RBC unit to audit (review) among all surgical procedures, including those previously studied. METHODS: This retrospective, observational study included 400,000 cases among 1891 different procedures over an 11-year period...
November 7, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29115972/plasmodium-reichenowi-eba-140-merozoite-ligand-binds-to-glycophorin-d-on-chimpanzee-red-blood-cells-shedding-new-light-on-origins-of-plasmodium-falciparum
#15
Agata Zerka, Radoslaw Kaczmarek, Marcin Czerwinski, Ewa Jaskiewicz
BACKGROUND: All symptoms of malaria are caused by the intraerythrocytic proliferation of Plasmodium merozoites. Merozoites invade erythrocytes using multiple binding ligands that recognise specific surface receptors. It has been suggested that adaptation of Plasmodium parasites to infect specific hosts is driven by changes in genes encoding Plasmodium erythrocyte-binding ligands (EBL) and reticulocyte-binding ligands (RBL). Homologs of both EBL and RBL, including the EBA-140 merozoite ligand, have been identified in P...
November 7, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29112161/collateral-damage-intended-cancer-associated-fibroblasts-and-vasculature-are-potential-targets-in-cancer-therapy
#16
REVIEW
Ana Cavaco, Maryam Rezaei, Stephan Niland, Johannes A Eble
After oncogenic transformation, tumor cells rewire their metabolism to obtain sufficient energy and biochemical building blocks for cell proliferation, even under hypoxic conditions. Glucose and glutamine become their major limiting nutritional demands. Instead of being autonomous, tumor cells change their immediate environment not only by their metabolites but also by mediators, such as juxtacrine cell contacts, chemokines and other cytokines. Thus, the tumor cells shape their microenvironment as well as induce resident cells, such as fibroblasts and endothelial cells (ECs), to support them...
November 7, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29107130/robotic-left-sided-level-ii-caval-thrombectomy-and-nephrectomy-using-a-novel-supine-single-dock-approach-primary-description
#17
Monty A Aghazadeh, Alvin C Goh
OBJECTIVES: To demonstrate a novel supine, single-dock approach for robotic nephrectomy and Inferior Vena Cava (IVC) thrombectomy for a left-sided renal cell carcinoma (RCC) with Level II IVC thrombus. METHODS: We perform robotic nephrectomy and IVC thrombectomy in a 79 year-old male with a 6cm left renal mass and level II IVC thrombus. For this approach, the patient is placed in steep Trendelenburg, and a 6-port transperitoneal technique is used, with the robot docked such that the arms are oriented in a cephalad direction...
October 26, 2017: Urology
https://www.readbyqxmd.com/read/29104784/external-validation-of-four-nephrometry-scores-for-trans-peritoneal-robotic-partial-nephrectomy
#18
Bhavan Prasad Rai, Amit Patel, Ahmed Abroaf, Narin Suleyman, Shanmugasundaram Gowriemohan, Venkat Prasad, Nikhil Vasdev, Jim Adshead
Introduction: External validation of four nephrometry scores (NS): Centrality index (C-index), arterial based complexity (ABC), preoperative aspects and dimensions used for an anatomical (PADUA) and radius expohytic/endophytic nearness anterior/posterior location (RENAL) scoring systems in patients who have undergone trans-peritoneal robotic assisted partial nephrectomy (RAPN). Material and methods: A prospective database for RAPN has been maintained. Individual NSs were performed on 3-dimensional reconstructions of MDCT/MRI studies retrospectively by a board certified uroradiologist...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/29083333/comparison-of-robotic-and-laparoscopic-radical-type-b-and-c-hysterectomy-for-cervical-cancer-long-term-outcomes
#19
Antonio Pellegrino, Gianluca Raffaello Damiani, Matteo Loverro, Cecilia Pirovano, Giorgio Fachechi, Silvia Corso, Giuseppe Trojano
STUDY OBJECTIVE: To compare the clinical and oncologic outcomes of Robotic radical hysterectomy (RRH) vs Laparoscopic radical hysterectomy (TLRH) in patients with cervical carcinoma. DESIGN: Long term follow-up in a prospective study between March 2010 to March 2016. SETTING: Oncological referral center, department of gynecology and obstetrics of Alessandro Manzoni Hospital, department of gynecology, University of San Gerardo Monza, Milan...
October 23, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29069168/epidemiology-and-health-services-25-years-in-review
#20
Juliana Gonçalves Reis, Elisete Duarte, Laeticia Jensen Eble, Leila Posenato Garcia
In 2017, Epidemiology and Health Services: journal of the Brazilian National Health System (RESS) celebrates 25 years. RESS was created in 1992 as SUS Epidemiological Report (IESUS) and, in 2003, adopted its current name and format. This study's objectives are to describe the subjects covered and the geographical spread of authors' institutions of the articles published in IESUS and RESS; and to map RESS' editorial policies and strategies in the following areas of focus: education, information, communication, co-responsibility and anticipation...
October 23, 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
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