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https://www.readbyqxmd.com/read/26853960/anti-gastric-ulcer-activity-of-polysaccharide-fraction-isolated-from-mycelium-culture-of-lion-s-mane-medicinal-mushroom-hericium-erinaceus-higher-basidiomycetes
#1
Mingxing Wang, Tetsuya Konishi, Yang Gao, Duoduo Xu, Qipin Gao
Hericium erinaceus is a culinary-medicinal mushroom that is used in traditional medicine, in folk medicine, and as medicinal cuisine in Asian countries such as China, Japan, and Korea. H. erinaceus exhibits various pharmacological properties, such as anti-cancer, immunomodulation, anti-dementia, and anti-gastric ulcer effects. The extracts of the fruiting body of H. erinaceus demonstrate anti-gastritis activity. However, the active principle in the extract, as well as the mechanism to treat gastric ulcers, remains uncertain...
2015: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/26853959/lion-s-mane-hericium-erinaceus-and-tiger-milk-lignosus-rhinocerotis-higher-basidiomycetes-medicinal-mushrooms-stimulate-neurite-outgrowth-in-dissociated-cells-of-brain-spinal-cord-and-retina-an-in-vitro-study
#2
Snehlata Samberkar, Sivasangkary Gandhi, Murali Naidu, Kah-Hui Wong, Jegadeesh Raman, Vikineswary Sabaratnam
Neurodegenerative disease is defined as a deterioration of the nervous system in the intellectual and cognitive capabilities. Statistics show that more than 80-90 million individuals age 65 and above in 2050 may be affected by neurodegenerative conditions like Alzheimer's and Parkinson's disease. Studies have shown that out of 2000 different types of edible and/or medicinal mushrooms, only a few countable mushrooms have been selected until now for neurohealth activity. Hericium erinaceus is one of the well-established medicinal mushrooms for neuronal health...
2015: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/26559695/the-anti-inflammatory-effects-of-lion-s-mane-culinary-medicinal-mushroom-hericium-erinaceus-higher-basidiomycetes-in-a-coculture-system-of-3t3-l1-adipocytes-and-raw264-macrophages
#3
Koichiro Mori, Kenji Ouchi, Noriyasu Hirasawa
Chronic low-grade inflammation in the adipose tissue accompanying obesity is thought to be an underlying driver of metabolic diseases. In this study, we aimed to investigate the efficacy of Hericium erinaceus on adipose tissue inflammation. The anti-inflammatory effects of the ethyl acetate soluble fraction of H. erinaceus (EAHE) were examined using cocultures of 3T3-L1 adipocytes and RAW264 macrophages. EAHE significantly suppressed tumor necrosis factor (TNF)-α and interleukin (IL)-6 production in cultured RAW264 macrophages stimulated by lipopolysaccharide (LPS)...
2015: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/26274992/endoscope-assisted-endonasal-versus-supraorbital-keyhole-resection-of-olfactory-groove-meningiomas-comparison-and-combination-of-2-minimally-invasive-approaches
#4
COMPARATIVE STUDY
Matei A Banu, Alpesh Mehta, Malte Ottenhausen, Justin F Fraser, Kunal S Patel, Oszkar Szentirmai, Vijay K Anand, Apostolos J Tsiouris, Theodore H Schwartz
OBJECTIVE: Although the endonasal endoscopic approach has been applied to remove olfactory groove meningiomas, controversy exists regarding the efficacy and safety of this approach compared with more traditional transcranial approaches. The endonasal endoscopic approach was compared with the supraorbital (eyebrow) keyhole technique, as well as a combined "above-and-below" approach, to evaluate the relative merits of each approach in different situations. METHODS: Nineteen cases were reviewed and divided according to operative technique into 3 different groups: purely endonasal (6 cases); supraorbital eyebrow (microscopic with endoscopic assistance; 7 cases); and combined endonasal endoscopic with either the bicoronal or eyebrow microscopic approach (6 cases)...
March 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/26244378/chemistry-nutrition-and-health-promoting-properties-of-hericium-erinaceus-lion-s-mane-mushroom-fruiting-bodies-and-mycelia-and-their-bioactive-compounds
#5
REVIEW
Mendel Friedman
The culinary and medicinal mushroom Hericium erinaceus is widely consumed in Asian countries, but apparently not in the United States, for its nutritional and health benefits. To stimulate broader interest in the reported beneficial properties, this overview surveys and consolidates the widely scattered literature on the chemistry (isolation and structural characterization) of polysaccharides and secondary metabolites such as erinacines, hericerins, hericenones, resorcinols, steroids, mono- and diterpenes, and volatile aroma compounds, nutritional composition, food and industrial uses, and exceptional nutritional and health-promoting aspects of H...
August 19, 2015: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/25954906/systemic-screening-of-strains-of-the-lion-s-mane-medicinal-mushroom-hericium-erinaceus-higher-basidiomycetes-and-its-protective-effects-on-a%C3%AE-triggered-neurotoxicity-in-pc12-cells
#6
Zongying Liu, Qinglong Wang, Jian Cui, Lili Wang, Lili Xiong, Wei Wang, Diqiang Li, Na Liu, Yiran Wu, Canquan Mao
Hericium erinaceus possesses multiple medicinal values. To date, however, there have been few studies of the systemic screening of H. erinaceus strains, and the neuroprotective effects of H. erinaceus prepared from homogenized, fresh fruiting bodies are not fully understood. In this study, 4 random primers were selected and used in random amplified polymorphic DNA (RAPD) polymerase chain reaction (PCR) to screen and evaluate the genetic diversity of 19 commercial strains of H. erinaceus from different localities in China...
2015: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/25306354/isolation-and-identification-of-aromatic-compounds-in-lion-s-mane-mushroom-and-their-anticancer-activities
#7
Wei Li, Wei Zhou, Eun-Ji Kim, Sang Hee Shim, Hee Kyoung Kang, Young Ho Kim
Lion's Mane Mushroom (Hericium erinaceum) is a traditional edible mushroom widely used in culinary applications and as an herbal medicine in East Asian countries. In the present study, two new aromatic compounds, hericerin A (1) and isohericenone J (5), along with five known compounds, isoericerin (2), hericerin (3), N-De phenylethyl isohericerin (4), hericenone J (6), and 4-[3',7'-dimethyl-2',6'-octadienyl]-2-formyl-3-hydroxy-5-methyoxybenzylalcohol (7), were isolated from a methanol extract of the fruiting bodies of H...
March 1, 2015: Food Chemistry
https://www.readbyqxmd.com/read/24959591/inhibitory-effect-on-in-vitro-ldl-oxidation-and-hmg-co-a-reductase-activity-of-the-liquid-liquid-partitioned-fractions-of-hericium-erinaceus-bull-persoon-lion-s-mane-mushroom
#8
Mohammad Azizur Rahman, Noorlidah Abdullah, Norhaniza Aminudin
Oxidation of low-density lipoprotein (LDL) has been strongly suggested as the key factor in the pathogenesis of atherosclerosis. Mushrooms have been implicated in having preventive effects against chronic diseases due especially to their antioxidant properties. In this study, in vitro inhibitory effect of Hericium erinaceus on LDL oxidation and the activity of the cholesterol biosynthetic key enzyme, 3-hydroxy-3-methyl glutaryl coenzyme A (HMG Co-A) reductase, was evaluated using five liquid-liquid solvent fractions consisting of methanol : dichloromethane (M : DCM), hexane (HEX), dichloromethane (DCM), ethyl acetate (EA), and aqueous residue (AQ)...
2014: BioMed Research International
https://www.readbyqxmd.com/read/24506286/vitamin-b12-c-lactone-a-biologically-inactive-corrinoid-compound-occurs-in-cultured-and-dried-lion-s-mane-mushroom-hericium-erinaceus-fruiting-bodies
#9
Fei Teng, Tomohiro Bito, Shigeo Takenaka, Yukinori Yabuta, Fumio Watanabe
This study determined the vitamin B12 content of the edible medicinal mushroom Hericium erinaceus, lion's mane mushroom fruiting body, using a microbiological assay based on Lactobacillus delbrueckii ATCC 7830. Trace levels (0.04-0.36 μg/100 g dry weight) of vitamin B12 were found in most of the dried mushroom samples, and two samples contained slightly higher levels (0.56 and 1.04 μg/100 g dry weight, respectively) of vitamin B12. We purified the corrinoid compounds from the extracts of dried lion's mane mushroom fruiting bodies using an immunoaffinity column and identified them as vitamin B12 or vitamin B12[c-lactone] (or both) based on LC/ESI-MS/MS chromatograms...
February 19, 2014: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/24329027/the-lion-s-mane-sign-surgical-results-using-the-bilateral-fronto-orbito-nasal-approach-in-large-and-giant-anterior-skull-base-meningiomas
#10
Maria S Li, Sandra Miller Portman, Akram Rahal, Gérard Mohr, Vijayabalan Balasingam
OBJECT: Concerns about extreme peritumoral edema and its ensuing surgical and perioperative complications led the authors to use the bilateral fronto-orbito-nasal approach to remove midline anterior skull base meningiomas that were larger than 4 cm. The authors hypothesize that extreme vasogenic edema exemplified by finger-like hyperintensities extending into the bifrontal white matter and external capsule and/or the extreme capsule, coined the lion's mane sign (LMS), would help identify patients with a challenging postoperative course...
February 2014: Journal of Neurosurgery
https://www.readbyqxmd.com/read/24302966/gastroprotective-effects-of-lion-s-mane-mushroom-hericium-erinaceus-bull-fr-pers-aphyllophoromycetideae-extract-against-ethanol-induced-ulcer-in-rats
#11
Jing-Yang Wong, Mahmood Ameen Abdulla, Jegadeesh Raman, Chia-Wei Phan, Umah Rani Kuppusamy, Shahram Golbabapour, Vikineswary Sabaratnam
Hericium erinaceus is a famous tonic in oriental medicine. The gastroprotective effects of aqueous extract of H. erinaceus against ethanol-induced ulcers in Sprague Dawley rats were investigated. The possible involvements of lipid peroxidation, superoxide dismutase, and catalase were also investigated. Acute toxicity study was performed. The effects of aqueous extract of H. erinaceus on the ulcer areas, ulcer inhibition, gastric wall mucus, gross and histological gastric lesions, antioxidant levels, and malondialdehyde (MDA) contents were evaluated in ethanol-induced ulcer in vivo...
2013: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/24266378/neurotrophic-properties-of-the-lion-s-mane-medicinal-mushroom-hericium-erinaceus-higher-basidiomycetes-from-malaysia
#12
Puei-Lene Lai, Murali Naidu, Vikineswary Sabaratnam, Kah-Hui Wong, Rosie Pamela David, Umah Rani Kuppusamy, Noorlidah Abdullah, Sri Nurestri A Malek
Neurotrophic factors are important in promoting the growth and differentiation of neurons. Nerve growth factor (NGF) is essential for the maintenance of the basal forebrain cholinergic system. Hericenones and erinacines isolated from the medicinal mushroom Hericium erinaceus can induce NGF synthesis in nerve cells. In this study, we evaluated the synergistic interaction between H. erinaceus aqueous extract and exogenous NGF on the neurite outgrowth stimulation of neuroblastoma-glioma cell NG108-15. The neuroprotective effect of the mushroom extract toward oxidative stress was also studied...
2013: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/23872357/sperm-quality-and-the-morphology-of-cryopreserved-testicular-tissues-recovered-post-mortem-from-diverse-wild-species
#13
Paweena Thuwanut, Sayamon Srisuwatanasagul, Grisnarong Wongbandue, Nae Tanpradit, Ampika Thongpakdee, Daraka Tongthainan, Sukanya Manee-In, Kaywalee Chatdarong
This study compared the effects of slow and fast freezing of testicular tissue of wild animals collected at post-mortem on testicular structure and testicular sperm. The testes of seven animals that had died in captivity; three felids (jungle cat, lion and leopard), two cervids (rusa deer and fea's muntjac) and two bovids (Sumatran serows) were cryopreserved using slow- and fast-freezing protocols. There were greater reductions in the integrity of the sperm membrane and DNA in tissues cryopreserved using slow freezing compared to fast freezing (membrane integrity reduced by 21...
October 2013: Cryobiology
https://www.readbyqxmd.com/read/23735479/hericium-erinaceus-an-edible-mushroom-with-medicinal-values
#14
REVIEW
Md Asaduzzaman Khan, Mousumi Tania, Rui Liu, Mohammad Mijanur Rahman
Mushrooms are considered as nutritionally functional foods and source of physiologically beneficial medicines. Hericium erinaceus, also known as Lion's Mane Mushroom or Hedgehog Mushroom, is an edible fungus, which has a long history of usage in traditional Chinese medicine. This mushroom is rich in some physiologically important components, especially β-glucan polysaccharides, which are responsible for anti-cancer, immuno-modulating, hypolipidemic, antioxidant and neuro-protective activities of this mushroom...
2013: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/23668749/hericium-erinaceus-lion-s-mane-mushroom-extracts-inhibit-metastasis-of-cancer-cells-to-the-lung-in-ct-26-colon-cancer-tansplanted-mice
#15
Sung Phil Kim, Seok Hyun Nam, Mendel Friedman
This study investigated the antimetastatic activity of four Hericium erinaceus edible mushroom extracts using CT-26 murine colon carcinoma cells as an indicator of inhibition of cell migration to the lung. Hot water (HWE) and microwaved 50% ethanol (MWE) extracts of H. erinaceus strongly elicited cancer cell death through apoptosis and inhibited metastasis of cancer cells to the lungs by 66% and 69%, respectively. HWE and MWE reduced the expression of matrix metalloproteinases MMP-2 and MMP-9 in cells and their activities in culture media...
May 22, 2013: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/23557368/in-vitro-anti-helicobacter-pylori-effects-of-medicinal-mushroom-extracts-with-special-emphasis-on-the-lion-s-mane-mushroom-hericium-erinaceus-higher-basidiomycetes
#16
Xiaodong Shang, Qi Tan, Ruina Liu, Kangying Yu, Pingzuo Li, Guo-Ping Zhao
Although the medicinal mushroom Hericium erinaceus is used extensively in traditional Chinese medicine to treat chronic superficial gastritis, the underlining pharmaceutical mechanism is yet to be fully understood. In this study, minimum inhibitory concentration (MIC) values of extracts prepared from the fruiting bodies of 14 mushroom species (H. erinaceus, Ganoderma lucidum, Cordyceps militaris, Pleurotus eryngii, P. ostreatus, Agrocybe aegerita, Lentinus edodes, Agaricus brasiliensis, A. bisporus, Coprinus comatus, Grifola frondosa, Phellinus igniarius, Flammulina velutipes, and Hypsizygus marmoreus) were determined against Helicobacter pylori using laboratory strains of ATCC 43504 and SS1 as well as 9 clinical isolates via an in vitro microplate agar diffusion assay...
2013: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/23510212/neuroregenerative-potential-of-lion-s-mane-mushroom-hericium-erinaceus-bull-fr-pers-higher-basidiomycetes-in-the-treatment-of-peripheral-nerve-injury-review
#17
REVIEW
Kah-Hui Wong, Murali Naidu, Rosie Pamela David, Robiah Bakar, Vikineswary Sabaratnam
We present a model case study of the activity of aqueous extract of Hericium erinaceus fresh fruit bodies in promoting functional recovery following crush injury to the peroneal nerve in adult female Sprague-Dawley rats. The aim was to explore the possible use of this mushroom in nerve repair. The activities of aqueous extract were compared to activities exhibited by mecobalamin (vitamin B12), which has been widely used in the treatment of peripheral nerve disorders. Analysis of walking track indicated that return of hind limb function and normal toe spreading occurred earlier in treated groups than in the negative control (non-treated) group...
2012: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/23505716/serologic-survey-of-infectious-diseases-in-populations-of-maned-wolf-chrysocyon-brachyurus-and-crab-eating-fox-cerdocyon-thous-from-aguas-emendadas-ecological-station-brazil
#18
Laila M Proença, Jean C R Silva, Paula D Galera, Marília B Lion, Jader S Marinho-Filho, Alessandra Mara Alves Ragozo, Solange Maria Gennari, J P Dubey, Silvio Arruda Vasconcellos, Gisele Oliveira Souza, José Wilton Pinheiro, Vânia Lúcia de Assis Santana, Gilvan L França, Flávio H G Rodrigues
Domestic dogs are reservoirs for many infectious diseases and may represent a potential source of infection for wild canid populations. A serologic investigation of antibodies to Toxoplasma gondii, Neospora caninum, Brucella abortus, and Leptospira spp. was conducted on three maned wolves (Chrysocyon brachyurus) and seven crab-eating foxes (Cerdocyon thous), all free-living, at the Aguas Emendadas Ecological Station (ESECAE), Federal District, Brazil, between February and October 2006. Out of the 10 samples analyzed, eight (80%) were seropositive for T...
March 2013: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/22536406/effect-of-sub-lethal-exposure-to-ultraviolet-radiation-on-the-escape-performance-of-atlantic-cod-larvae-gadus-morhua
#19
Yuichi Fukunishi, Howard I Browman, Caroline M F Durif, Reidun M Bjelland, Anne Berit Skiftesvik
UNLABELLED: The amount of ultraviolet (UV) radiation reaching the earth's surface has increased due to depletion of the ozone layer. Several studies have reported that UV radiation reduces survival of fish larvae. However, indirect and sub-lethal impacts of UV radiation on fish behavior have been given little consideration. We observed the escape performance of larval cod (24 dph, SL: 7.6±0.2 mm; 29 dph, SL: 8.2±0.3 mm) that had been exposed to sub-lethal levels of UV radiation vs. unexposed controls...
2012: PloS One
https://www.readbyqxmd.com/read/22438906/jellyfish-support-high-energy-intake-of-leatherback-sea-turtles-dermochelys-coriacea-video-evidence-from-animal-borne-cameras
#20
Susan G Heaslip, Sara J Iverson, W Don Bowen, Michael C James
The endangered leatherback turtle is a large, highly migratory marine predator that inexplicably relies upon a diet of low-energy gelatinous zooplankton. The location of these prey may be predictable at large oceanographic scales, given that leatherback turtles perform long distance migrations (1000s of km) from nesting beaches to high latitude foraging grounds. However, little is known about the profitability of this migration and foraging strategy. We used GPS location data and video from animal-borne cameras to examine how prey characteristics (i...
2012: PloS One
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