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https://www.readbyqxmd.com/read/27926659/macroprolactinomas-and-nonfunctioning-pituitary-adenomas-and-pregnancy-outcomes
#1
Kimberley Lambert, Kate Rees, Paul T Seed, Mandish K Dhanjal, Marian Knight, David R McCance, Catherine Williamson
OBJECTIVE: To examine the monitoring, management, and outcomes of pituitary tumors in pregnancy. METHODS: A national, prospective, observational, population-based case series study was conducted in all U.K. consultant-led obstetric units over 3 years using the U.K. Obstetric Surveillance System. To evaluate rates of adverse pregnancy outcomes, women with a macroprolactinoma (10 mm or greater) or nonfunctioning pituitary adenoma, diagnosed before or during pregnancy, were compared with two comparison groups: 1) a U...
December 2, 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27925622/relation-between-amniotic-fluid-infection-or-cytokine-levels-and-hearing-screen-failure-in-infants-at-32-wk-gestation-or-less
#2
Eun Young Jung, Byung Yoon Choi, Jihye Rhee, Jaehong Park, Soo-Hyun Cho, Kyo Hoon Park
BACKGROUND: To determine whether the presence of intra-amniotic infection and elevated proinflammatory cytokine levels in amniotic fluid (AF) are associated with failure in the newborn hearing screen (NHS) test in very preterm neonates. METHODS: This is a retrospective cohort study of 112 premature singleton neonates born to women with preterm labor or preterm premature rupture of membranes at ≤32 wk. AF obtained through amniocentesis was cultured, and interleukin-6 (IL-6) and IL-8 levels were determined...
December 7, 2016: Pediatric Research
https://www.readbyqxmd.com/read/27903080/inter-pregnancy-interval-and-adverse-outcomes-evidence-for-an-additional-risk-in-health-disparate-populations
#3
Shyama Appareddy, Jason Pryor, Beth Bailey
OBJECTIVE: Short interpregnancy interval (IPI), <18 months between pregnancies, is a potential cause of adverse delivery and birth outcomes, and may be a particular issue among those with other risks. Our goal was to examine IPI and delivery/infant complications in Tennessee. METHODS: Birth certificate/vital records data included 101,912 women with a previous delivery. IPI groups (<6, 6-12, 12-18, 18-60 months) were compared on outcomes. RESULTS: Thirty-nine percent of the deliveries had IPI <18 months, 9% were <6 months, rates 11% and 27% higher than nationally...
December 1, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27896247/uterine-rupture-in-pregnancies-following-myomectomy-a-multicenter-case-series
#4
Hee-Sun Kim, Soo-Young Oh, Suk-Joo Choi, Hyun-Soo Park, Geum-Joon Cho, Jin-Hoon Chung, Yong-Soo Seo, Sun-Young Jung, Jung-Eun Kim, Su-Hyun Chae, Han-Sung Hwang
OBJECTIVE: The purpose of this case series was to retrospectively examine records of cases with uterine rupture in pregnancies following myomectomy and to describe the clinical features and pregnancy outcomes. METHODS: This study was conducted as a multicenter case series. The patient databases at 7 tertiary hospitals were queried. Records of patients with a diagnosis of uterine rupture in the pregnancy following myomectomy between January 2012 and December 2014 were retrospectively collected...
November 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27895514/success-rate-in-preterm-uterine-contraction-inhibition-with-tocolytic-agents-in-a-tertiary-care-center
#5
Duangsamorn Kiatsuda, Jadsada Thinkhamrop, Witoon Prasertcharoensuk
OBJECTIVE: This study aims to assess the success rate of inhibiting preterm uterine contraction with tocolytic agents to delay delivery for at least 48 hours and risk factors of failure inhibition. MATERIALS AND METHODS: Between January 2013 and July 2014, medical records of all singleton pregnant women between 24 (0/7) and 33 (6/7) weeks of gestation with the diagnosis of preterm labor (with cervical dilatation) or threatened preterm labor (without cervical dilatation) who received tocolytic agents were reviewed...
2016: International Journal of Women's Health
https://www.readbyqxmd.com/read/27885286/immediate-outcome-of-hypoxic-ischaemic-encephalopathy-in-hypoxiate-newborns-in-nepal-medical-college
#6
S Shrestha, G S Shrestha, A Sharma
BACKGROUND: Birth asphyxia is the fifth major cause of under-five child deaths after pneumonia, diarrhoea, neonatal infections and complications of preterm birth. It is one of the important causes of neonatal mortality and morbidity accounting up to 30% of neonatal death in Nepal. It is also an important cause of long-term neurological disability and impairment. The mortality rate due to birth asphyxia is considered a good guide to the quality of perinatal care. This study was conducted to assess the rate of birth asphyxia, risk factors and outcome of the babies who were asphyxiated at birth...
May 2016: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/27879326/effects-of-levothyroxine-treatment-on-pregnancy-outcomes-in-pregnant-women-with-autoimmune-thyroid-disease
#7
Sima Nazarpour, Fahimeh Ramezani Tehrani, Masoumeh Simbar, Maryam Tohidi, Hamid Alavi Majd, Fereidoun Azizi
BACKGROUND: Despite some studies indicating that thyroid antibody positivity during pregnancy has been associated with adverse pregnancy outcomes, evidence regarding the effects of levothyroxine (LT4) treatment of euthyroid/subclinical hypothyroid pregnant women with autoimmune thyroid disease on pregnancy outcome is limited. We aimed to assess whether pregnant women with autoimmune thyroid disease, but without overt thyroid dysfunction are affected by higher rates of adverse pregnancy outcomes...
November 22, 2016: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27872420/role-of-cervical-length-measurement-for-preterm-delivery-prediction-in-women-with-threatened-preterm-labor-and-cervical-dilatation
#8
Liran Hiersch, Nir Melamed, Amir Aviram, Ron Bardin, Yariv Yogev, Eran Ashwal
OBJECTIVES: To compare the accuracy and cutoff points for cervical length for predicting preterm delivery in women with threatened preterm labor between those with a closed cervix and cervical dilatation. METHODS: We conducted a retrospective cohort study of women with singleton pregnancies with threatened preterm labor before 34 weeks. The accuracy of cervical length for predicting preterm delivery was compared between women with cervical dilatation (0.5-3 cm) and those with a closed cervix...
December 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27870810/neonatal-group-b-streptococcus-infections-prevention-strategies-clinical-and-microbiologic-characteristics-in-7-years-of-surveillance
#9
Roberta Creti, Monica Imperi, Alberto Berardi, Marco Pataracchia, Simona Recchia, Giovanna Alfarone, Lucilla Baldassarri
BACKGROUND: The characteristics of group B streptococcus (GBS) neonatal disease in a period of 7 years are reported. METHODS: The estimation of the neonatal GBS disease risk and prevention strategies adopted at delivery in absence of national guidelines were evaluated by the analysis of 3501 questionnaires. Notification of 194 neonatal GBS infections was recorded. In addition, 115 strains from neonatal early and late onset disease (EOD and LOD, respectively) plus 320 strains from pregnant women were analyzed by molecular typing methods and for antibiotic resistance...
November 18, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27865977/racial-ethnic-differences-in-preterm-perinatal-outcomes
#10
Maeve E Wallace, Pauline Mendola, Sung Soo Kim, Nikira Epps, Zhen Chen, Melissa Smarr, Stefanie N Hinkle, Yeyi Zhu, Katherine L Grantz
BACKGROUND: Racial disparities in preterm birth and infant death have been well documented. Less is known about racial disparities in neonatal morbidities among infants who are born at <37 weeks of gestation. OBJECTIVE: The purpose of this study was to determine whether the risk for morbidity and death among infants who are born preterm differs by maternal race. STUDY DESIGN: A retrospective cohort design included medical records from preterm deliveries of 19,325 black, Hispanic, and white women in the Consortium on Safe Labor...
November 16, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27865975/differences-in-placental-telomere-length-suggest-a-link-between-racial-disparities-in-birth-outcomes-and-cellular%C3%A2-aging
#11
Christopher W Jones, Cecilia Gambala, Kyle C Esteves, Maeve Wallace, Reid Schlesinger, Marguerite O'Quinn, Laura Kidd, Katherine P Theall, Stacy S Drury
BACKGROUND: Health disparities begin early in life and persist across the life course. Despite current efforts, black women exhibit greater risk for pregnancy complications and negative perinatal outcomes compared with white women. The placenta, which is a complex multi-tissue organ, serves as the primary transducer of bidirectional information between the mother and fetus. Altered placental function is linked to multiple racially disparate pregnancy complications; however, little is known about racial differences in molecular factors within the placenta...
November 16, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27836377/-prevention-of-spontaneous-preterm-birth-excluding-preterm-premature-rupture-of-membranes-guidelines-for-clinical-practice%C3%A2-%C3%A2-text-of-the-guidelines-short-text
#12
L Sentilhes, M-V Sénat, P-Y Ancel, E Azria, G Benoist, J Blanc, G Brabant, F Bretelle, S Brun, M Doret, C Ducroux-Schouwey, A Evrard, G Kayem, E Maisonneuve, L Marcellin, S Marret, N Mottet, S Paysant, D Riethmuller, P Rozenberg, T Schmitz, H Torchin, B Langer
OBJECTIVES: To determine the measures to prevent spontaneous preterm birth (excluding preterm premature rupture of membranes)and its consequences. MATERIALS AND METHODS: The PubMed database, the Cochrane Library and the recommendations from the French and foreign obstetrical societies or colleges have been consulted. RESULTS: In France, premature birth concerns 60,000 neonates every year (7.4 %), half of them are delivered after spontaneous onset of labor...
November 8, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27821985/perinatal-outcome-of-the-second-twin-at-a-tertiary-care-center-in-india
#13
Hiralal Konar, Madhutandra Sarkar, Joydip Paul
PURPOSE: This cross-sectional observational study was undertaken to assess perinatal outcome of the second twin in respect to gestational age, presentation, mode of delivery, and birth weight. METHODS: Seventy women with confirmed twin pregnancy were admitted and managed in a tertiary care teaching hospital in Kolkata, India from May 2008 to April 2009. All relevant data were recorded and analyzed statistically by simple proportions and χ(2) test. RESULTS: Women with frequent antenatal visits had highly favorable perinatal outcome than those with fewer or no visits in this hospital (p < 0...
December 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27810166/stressful-life-event-experiences-of-pregnant-women-in-the-united-states-a-latent-class-analysis
#14
Soumyadeep Mukherjee, Stefany Coxe, Kristopher Fennie, Purnima Madhivanan, Mary Jo Trepka
OBJECTIVES: Nearly 65% to 70% of pregnant women in the United States experience one or more stressful life events (SLEs), which can lead to adverse maternal and/or fetal outcomes. This study aimed to identify groups of women with similar patterns of antenatal SLE experiences, and to examine their sociodemographic correlates. METHODS: Data from the 2009 to 2011 Pregnancy Risk Assessment Monitoring System were used and latent class analysis performed (N = 115,704) to identify unobserved class membership...
October 31, 2016: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/27790344/factors-associated-with-preterm-labor-in-hormozgan-province-in-2013
#15
Nasibeh Roozbeh, Soheila Moradi, Shirin Soltani, Fatemeh Zolfizadeh, Mehdi Tadris Hasani, Asiyeh Pormehr Yabandeh
INTRODUCTION: Preterm labor is the main cause of infants' death, and the main reason for undesirable consequences of pregnancy which still occur in some births, despite all of the interventions in this regard. The aim of this study was to evaluate every preterm birth and determine its maternal risk factors in Hormozgan province in 2013. METHODS: This case-control study was conducted in 2013 on the health and hospital records of 735 pregnant mothers with preterm labor (20-37 weeks) which were located in Bandar Abbas in southeast Iran...
September 2016: Electronic Physician
https://www.readbyqxmd.com/read/27789055/-epidemiology-and-risk-factors-of-preterm-birth
#16
H Torchin, P-Y Ancel
OBJECTIVE: To synthesize the available evidence regarding the incidence and several risk factors of preterm birth. To describe neonatal outcomes according to gestational age and to the context of delivery. MATERIALS AND METHODS: Consultation of the Medline database. RESULTS: In 2010, 11% of live births (15 million babies) occurred before 37 completed weeks of gestation worldwide. About 85% of these births were moderate to late preterm babies (32-36 weeks), 10% were very preterm babies (28-31 weeks) and 5% were extremely preterm babies (<28 weeks)...
October 24, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27789054/-management-of-preterm-labor
#17
G Kayem, E Lorthe, M Doret
OBJECTIVE: To define the management of preterm labor (MAP). METHOD: The literature search was conducted using computer databases Medline and the Cochrane Library for a period from 1969 to March 2016. RESULTS: Leukocytosis screening may be useful in case of hospitalization for Preterm labor (PTL). Its use is not routine (professional consensus). Screening for urinary tract infection by urine culture should be systematic and antibiotic treatment should be performed in cases of bacterial colonization or urinary tract infection for a period of 7 days (grade A)...
October 24, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27788742/-the-outcome-of-trial-of-labor-after-cesarean-section
#18
Z Q Qu, R M Ma, H Xiao, Y Q Tian, B L Li, K Liang, M Y Du, Z Chen, L Geng, M H Yang, Y P Tao, B Zhu
Objective: To explore the outcome of trial of labor after cesarean section(TOLAC). Methods: Totally 614 TOLAC were conducted in the First Affiliated Hospital of Kunming Medical University from July 2013 to June 2016. Among them, 586 cases of singleton pregnancy with one prior cesarean section(gestational age≥28 weeks)were studied retrospectively. The maternal and neonatal outcomes among the vaginal birth after cesarean(VBAC)group(481 cases), failed TOLAC group(105 cases)and the elective repeat cesarean section(ERCS)group(1 145 cases)were compared...
October 25, 2016: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/27783473/impact-of-azithromycin-on-pregnancy-prolongation-in-women-at-risk-of-preterm-labor-a-time-to-event-analysis
#19
Isabelle Goyer, Gabrielle Ferland, Ni Ruo, Caroline Morin, Marie-Sophie Brochet, Lucie Morin, Ema Ferreira
BACKGROUND: Since 2006, the empiric use of azithromycin in women at risk of premature birth has become prevalent in our institution without any evidence of its efficacy. Although antibiotics can prolong pregnancy in preterm prolonged rupture of membranes, no published data are available for women with intact membranes. OBJECTIVES: To describe the purpose of adding azithromycin to the usual treatments (cerclage, tocolysis, rest, etc.) to prolong pregnancy in women with intact membranes who are at risk of or already in preterm labour...
September 13, 2016: Journal of Population Therapeutics and Clinical Pharmacology
https://www.readbyqxmd.com/read/27780701/threatened-preterm-labor-is-a-risk-factor-for-impaired-cognitive-development-in-early-childhood
#20
Cristina Paules, Victoria Pueyo, Elena Martí, Susana Vilchez, Irina Burd, Pilar Calvo, Daniel Oros
BACKGROUND: Threatened preterm labor is a leading cause of hospital admission during pregnancy. Patients presenting with an episode of threatened preterm labor who deliver at term are considered to have false preterm labor. However, threatened preterm labor has been proposed as a pathological insult that is not always sufficient to induce irreversible spontaneous preterm birth but that could alter the normal course of pregnancy. OBJECTIVE: The aim of this study was to evaluate threatened preterm labor during pregnancy as a risk factor of neurodevelopmental deficits of children at 2 years of age...
October 22, 2016: American Journal of Obstetrics and Gynecology
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