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https://www.readbyqxmd.com/read/29052225/peripheral-nerve-block-in-ankle-fracture-surgery-a-qualitative-study-of-patients-experiences
#1
M J Henningsen, R Sort, A M Møller, S F Herling
Peripheral nerve blocks are popular as a mode of anaesthesia for limb surgery and their beneficial effects are well documented in elective surgery. However, concerns have been raised about potential rebound pain outweighing the benefits in acute ankle fracture surgery. Furthermore, pain scores and morphine consumption do not provide a full picture, as pain is subjective. To evaluate the clinical usefulness of peripheral nerve blocks, we explored patients' expectations and experiences by means of semi-structured interviews analysed with systematic text condensation...
October 19, 2017: Anaesthesia
https://www.readbyqxmd.com/read/29040222/neurovascular-response-during-exercise-and-mental-stress-in-anabolic-steroid-users
#2
Rafael Armani Porello, Marcelo Rodrigues Dos Santos, Francis Ribeiro de Souza, Guilherme Wesley Peixoto da Fonseca, Ana Luiza Carrari Sayegh, Tiago Franco de Oliveira, César Abreu Akiho, Maurício Yonamine, Rosa Maria Rodrigues Pereira, Carlos Eduardo Negrão, Maria-Janieire de Nazaré Nunes Alves
PURPOSE: Increased resting muscle sympathetic nerve activity (MSNA) and lower forearm blood flow (FBF) were observed in young men who use anabolic androgenic steroids (AAS). However, the response of MSNA and FBF in AAS users triggered by muscle mechanoreflex and central command has never been tested. Additionally, we evaluated the blood pressure (BP) and heart rate (HR) responses during these maneuvers. METHODS: Nineteen AAS users (AASU) aged 31±6 yr and 18 AAS nonusers (AASNU) aged 29±4 yr were recruited...
October 16, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29026613/a-case-of-generalized-argyria-presenting-with-muscle-weakness
#3
Inha Jung, Eun-Jeong Joo, Byung Seong Suh, Cheol-Bae Ham, Ji-Min Han, You-Gyung Kim, Joon-Sup Yeom, Ju-Yeon Choi, Ji-Hye Park
BACKGROUND: Argyria is a rare irreversible cutaneous pigmentation disorder caused by prolonged exposure to silver. Herein, we report a case of generalized argyria that developed after chronic ingestion of soluble silver-nano particles and presented with muscle weakness. CASE PRESENTATION: A 74-year-old woman visited our emergency room, complaining of fever and mental deterioration. She was diagnosed with acute pyelonephritis and recovered after antibiotic therapy...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29019277/3d-cbct-morphometric-assessment-of-mental-foramen-in-arabic-population-and-global-comparison-imperative-for-invasive-and-non-invasive-procedures-in-mandible
#4
Mohammad Khursheed Alam, Selham Alhabib, Bader K Alzarea, Muhammad Irshad, Saif Faruqi, Mohd G Sghaireen, Santosh Patil, Rehana Basri
BACKGROUND: Recent advancements in clinical dentistry have increased the possibilities of surgical procedures in the mental region. A detailed knowledge of mental foramen (MF) morphometry is significant to preserve integrity of the mental nerve trunk in surgical interventions such as orthognathic surgery, implant placement and anaesthetic block. OBJECTIVE: The aim of this study was to determine the most accurate position of the mental foramen by using new assessment approach in a sample of dental patients presenting to the specialist dental clinic, College of Dentistry, Al Jouf University, Saudi Arabia...
October 11, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/29016169/the-microbiome-as-a-novel-paradigm-in-studying-stress-and-mental-health
#5
Richard T Liu
At the intersection between neuroscience, microbiology, and psychiatry, the enteric microbiome has potential to become a novel paradigm for studying the psychobiological underpinnings of mental illness. Several studies provide support for the view that the enteric microbiome influences behavior through the microbiota-gut-brain axis. Moreover, recent findings are suggestive of the possibility that dysregulation of the enteric microbiota (i.e., dysbiosis) and associated bacterial translocation across the intestinal epithelium may be involved in the pathophysiology of stress-related psychiatric disorders, particularly depression...
October 2017: American Psychologist
https://www.readbyqxmd.com/read/28970198/sympathetic-neural-reactivity-to-mental-stress-differs-in-black-and-non-hispanic-white-adults
#6
Ida T Fonkoue, Christopher E Schwartz, Min Wang, Jason R Carter
Black adults have a higher risk of hypertension compared to non-Hispanic white (NHW) adults, but physiological mechanisms underlying this predisposition remain unclear. This study compared muscle sympathetic nerve activity (MSNA) responses to mental stress in a group of young black and NHW participants. We hypothesized that the sympathoexcitation associated with mental stress would be greater in black adults compared to NHW. Thirty-five male adults (19 black, 23±1 years; 16 NHW, 22±1 years) were examined during a 5 min supine baseline and 5 min of mental stress (via mental arithmetic)...
September 28, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28968326/intraoral-observation-of-the-mentalis-and-incisivus-labii-inferioris-muscles
#7
Joe Iwanaga, Puhan He, Koichi Watanabe, Yasuhiko Kamura, Rod J Oskouian, R Shane Tubbs
The mentalis (MT) and the incisivus labii inferioris (ILI), which are accessory muscles of the orbicularis oris (OO) muscle, form an intertwined and three-dimensionally related complex. The purpose of this study is to clarify the relationship between the MT, ILI, and OO muscles via intraoral dissection. Twenty-two sides from 11 fresh adult Caucasian cadaveric heads were used, and the MT, ILI, and OO dissected under the surgical microscope. Next, measurements of the bony attachment were carried out on another 12 sides...
September 29, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28966226/2-ethylpyrazine-induces-vasodilatation-by-releasing-nitric-oxide-in-the-endothelium
#8
Hiroshi Ashigai, Emiko Ikeshima, Kumiko Koizumi, Keiko Nakashima, Mai Mizutani, Hiroaki Yajima
Oxygen transportation and regulation of some physiological processes are facilitated by blood flow. Furthermore, blood flow is regulated by various factors such as nitric oxide (NO) and the autonomic nerve system. In modern life, many people suffer from chilliness (hiesho) because of mental stress and an excessive use air-conditioning systems, which induces vasoconstriction in the peripheral skin. In this study, we focused on pyrazine derivatives, particularly compounds that are used as food flavoring materials, and investigated their effects on vascular function and blood flow...
September 29, 2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28958599/abnormal-cortical-asymmetry-as-a-target-for-neuromodulation-in-neuropsychiatric-disorders-a-narrative-review-and-concept-proposal
#9
REVIEW
Randy W Beck, Jonathan Laugharne, Richard Laugharne, Wessel Woldman, Brendan McLean, Chiara Mastropasqua, Ricardo Jorge, Rohit Shankar
Recent advances in knowledge relating to the organization of neural circuitry in the human brain have increased understanding of disorders involving brain circuit asymmetry. These asymmetries, which can be measured and identified utilizing EEG and LORETA analysis techniques, may be a factor in mental disorders. New treatments involving non-invasive brain stimulation (NIBS), including trans-cranial magnetic stimulation, direct current stimulation and vagal nerve stimulation, have emerged in recent years. We propose that EEG identification of circuit asymmetry geometries can direct non-invasive brain stimulation more specifically for treatments of mental disorders...
September 25, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28951641/midterm-radiologic-and-functional-outcomes-of-minimally-invasive-fixation-of-unstable-pelvic-fractures-using-anterior-internal-fixator-infix-and-percutaneous-iliosacral-screws
#10
Ajoy Prasad Shetty, Aju Bosco, Ramesh Perumal, Jeyaramaraju Dheenadhayalan, Shanmuganathan Rajasekaran
BACKGROUND: Anterior pelvic external fixation is associated with pin site infections, aseptic loosening with loss of reduction, frame bulkiness hindering patient mobilization and consequent difficulties in inpatient nursing. We performed a single-center prospective series to evaluate the feasibility, safety, limitations and midterm radiologic and functional outcomes of an alternative minimally invasive pelvic internal fixation technique using an anterior subcutaneous pelvic internal fixator (INFIX) and percutaneous iliosacral screws in unstable pelvic ring fractures...
July 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28921418/coping-with-phantom-limb-pain
#11
Damien P Kuffler
Phantom limb pain is a chronic neuropathic pain that develops in 45-85% of patients who undergo major amputations of the upper and lower extremities and appears predominantly during two time frames following an amputation: the first month and later about 1 year. Although in most patients the frequency and intensity of pain diminish over time, severe pain persists in about 5-10%. It has been proposed that factors in both the peripheral and central nervous systems play major roles in triggering the development and maintenance of pain associated with extremity amputations...
September 18, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28894661/patient-reported-disability-measures-do-not-correlate-with-electrodiagnostic-severity-in-carpal-tunnel-syndrome
#12
Jacob E Tulipan, Kevin F Lutsky, Mitchell G Maltenfort, Mitchell K Freedman, Pedro K Beredjiklian
BACKGROUND: Electrophysiologic studies including electromyography and nerve conduction studies play a role in the evaluation of carpal tunnel syndrome (CTS), despite evidence that these studies do not correlate with CTS-specific symptom scores. There is a lack of evidence comparing electrophysiologic data with general measures of function. METHODS: Fifty patients presenting for CTS treatment over an 8-month period were analyzed retrospectively. All patients completed surveys including the Quick Disabilities of the Arm, Shoulder, and Hand questionnaire (DASH) and the Medical Outcomes Study 12-Item Short-Form Survey [(physical component summary 12, mental component summary (MCS-12)]...
August 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28894304/quantification-of-brain-cholinergic-denervation-in-alzheimer-s-disease-using-pet-imaging-with-18-f-feobv
#13
M Aghourian, C Legault-Denis, J-P Soucy, P Rosa-Neto, S Gauthier, A Kostikov, P Gravel, M-A Bédard
(18)F-fluoroethoxybenzovesamicol (FEOBV) is a new PET radiotracer that binds to the vesicular acetylcholine transporter. In both animals and healthy humans, FEOBV was found sensitive and reliable to characterize presynaptic cholinergic nerve terminals in the brain. It has been used here for we believe the first time in patients with Alzheimer's disease (AD) to quantify brain cholinergic losses. The sample included 12 participants evenly divided in healthy subjects and patients with AD, all assessed with the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) cognitive scales...
September 12, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28877292/safety-and-outcomes-of-the-transoral-endoscopic-thyroidectomy-vestibular-approach
#14
Angkoon Anuwong, Khwannara Ketwong, Pornpeera Jitpratoom, Thanyawat Sasanakietkul, Quan-Yang Duh
Importance: Natural orifice transluminal endoscopic surgery thyroidectomy is a novel approach to avoid surgical scars. Objective: To compare the safety and outcomes of the transoral endoscopic thyroidectomy vestibular approach (TOETVA) with those of open thyroidectomy (OT). Design, Setting, and Participants: This study retrospectively reviewed all TOETVA and OT operations performed from April 1, 2014, through August 31, 2016, at Police General Hospital, Bangkok, Thailand...
September 6, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28873063/a-descriptive-cross-sectional-study-to-assess-quality-of-life-and-sexuality-in-turkish-patients-with-a-colostomy
#15
Emel Yilmaz, Dilruba Çelebi, Yavuz Kaya, Hakan Baydur
A stoma affects personality, self-esteem, and body image, inevitably impacting lifestyle and quality of life (QOL). A descriptive, cross-sectional study was conducted between May 1, 2015 and May 1, 2016 to evaluate the effect of a stoma on sexual function and QOL among patients receiving care in a general surgery clinic of a university hospital in the western region of Turkey.Eligibility requirements included patients willing to participate, >18 years of age, with a colostomy for at least 4 months, who were married and/or with a sexual partner and in otherwise good physical and mental health with no rectal nerve damage or receiving radio- or chemotherapy...
August 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/28860965/resetting-of-the-baroreflex-control-of-sympathetic-vasomotor-activity-during-natural-behaviors-description-and-conceptual-model-of-central-mechanisms
#16
REVIEW
Roger A L Dampney
The baroreceptor reflex controls arterial pressure primarily via reflex changes in vascular resistance, rather than cardiac output. The vascular resistance in turn is dependent upon the activity of sympathetic vasomotor nerves innervating arterioles in different vascular beds. In this review, the major theme is that the baroreflex control of sympathetic vasomotor activity is not constant, but varies according to the behavioral state of the animal. In contrast to the view that was generally accepted up until the 1980s, I argue that the baroreflex control of sympathetic vasomotor activity is not inhibited or overridden during behaviors such as mental stress or exercise, but instead is reset under those conditions so that it continues to be highly effective in regulating sympathetic activity and arterial blood pressure at levels that are appropriate for the particular ongoing behavior...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28839226/provision-of-somatosensory-inputs-during-motor-imagery-enhances-learning-induced-plasticity-in-human-motor-cortex
#17
Gaia Bonassi, Monica Biggio, Ambra Bisio, Piero Ruggeri, Marco Bove, Laura Avanzino
Motor learning via physical practice leads to long-term potentiation (LTP)-like plasticity in motor cortex (M1) and temporary occlusion of additional LTP-like plasticity. Motor learning can be achieved through simulation of movement, namely motor imagery (MI). When combined with electrical stimulation, MI influenced M1 excitability to a larger extent than MI itself. We explored whether a training based on the combination of MI and peripheral nerve stimulation (ESMI) modulates M1 LTP-like plasticity inducing retention of a new acquired skill...
August 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28838820/safe-zone-in-anterior-mandible-related-to-the-genial-tubercle-for-implant-osteotomy-in-a-chinese-malaysian-population-a-cbct-study
#18
Yik Sze Voon, Pravinkumar G Patil
STATEMENT OF PROBLEM: The genial tubercle is a clinically palpable landmark in the mandible and can be identified in cone beam computed tomography (CBCT). Its location can be used to measure the safe zone in the interforaminal region of the mandible. These measurements may be helpful for implant treatment planning in patients with complete edentulism. PURPOSE: The purpose of this clinical study was to evaluate the safe distance in the interforaminal region of the mandible measured from the genial tubercle level for implant osteotomy in a Chinese-Malaysian population...
August 22, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28835882/transoral-endoscopic-thyroidectomy-for-papillary-thyroid-microcarcinoma-initial-experience-of-a-single-surgeon
#19
Young Jun Chai, Jung Kee Chung, Angkoon Anuwong, Gianlorenzo Dionigi, Hoon Yub Kim, Ki-Tae Hwang, Seung Chul Heo, Ka Hee Yi, Kyu Eun Lee
PURPOSE: Recently, transoral endoscopic thyroidectomy (TOET) is receiving attention because it is regarded as a true minimally invasive surgery in that it does not leave scars on any part of the body and the area of flap dissection is similar to that of open surgery. In this study, we present the surgical procedures and initial outcomes of TOET in the treatment of papillary thyroid microcarcinoma (PTMC) patients. METHODS: The medical records of patients who underwent TOET for PTMC between July 2016 and February 2017 were retrospectively reviewed...
August 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28835258/acute-hypopituitarism-associated-with-periorbital-swelling-and-cardiac-dysfunction-in-a-patient-with-pituitary-tumor-apoplexy-a-case-report
#20
Nobumasa Ohara, Yuichiro Yoneoka, Yasuhiro Seki, Katsuhiko Akiyama, Masataka Arita, Kazumasa Ohashi, Kazuo Suzuki, Toshinori Takada
BACKGROUND: Pituitary tumor apoplexy is a rare clinical syndrome caused by acute hemorrhage or infarction in a preexisting pituitary adenoma. It typically manifests as an acute episode of headache, visual disturbance, mental status changes, cranial nerve palsy, and endocrine pituitary dysfunction. However, not all patients present with classical symptoms, so it is pertinent to appreciate the clinical spectrum of pituitary tumor apoplexy presentation. We report an unusual case of a patient with pituitary tumor apoplexy who presented with periorbital edema associated with hypopituitarism...
August 24, 2017: Journal of Medical Case Reports
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