Silke Steinbach, Thomas Hummel, Christina Böhner, Sabina Berktold, Walter Hundt, Monika Kriner, Petra Heinrich, Harald Sommer, Claus Hanusch, Anita Prechtl, Burghart Schmidt, Ingo Bauerfeind, Katharina Seck, Volker R Jacobs, Barbara Schmalfeldt, Nadia Harbeck
PURPOSE: Smell and taste changes during chemotherapy are significant complaints of cancer patients. Loss of olfactory/gustatory function can lead to malnutrition, weight loss, and possibly a prolonged morbidity of chemotherapy-induced adverse effects, decreased quality of life, poor compliance, and even decreased therapy response. This prospective study comprehensively investigated, to our knowledge for the first time, smell and taste changes in a cohort of 87 patients undergoing chemotherapy for breast cancer or gynecologic malignancies...
April 10, 2009: Journal of Clinical Oncology