Eugenio De Corso, Davide Paolo Porru, Marco Corbò, Claudio Montuori, Gabriele De Maio, Rodolfo Francesco Mastrapasqua, Marco Panfili, Camilla Spanu, Giuseppe Alberto Di Bella, Giuseppe D'Agostino, Alberta Rizzuti, Giulio Cesare Passali, Jacopo Galli
INTRODUCTION: Management of severe chronic rhinosinusitis with nasal polyps (CRSwNP) has changed significantly in recent years, with different treatments now available including biologics and endoscopic sinus surgery (ESS), although there are still few comparative studies. We aimed to compare 1-year outcomes of patients with severe CRSwNP treated with dupilumab or ESS plus intranasal corticosteroids (INCS). METHODS: In this retrospective, real-life, observational, cohort study, we enrolled 101 patients with severe CRSwNP who were treated with INCS and either ESS (n = 49) or dupilumab (n = 52)...
May 6, 2024: Clinical Otolaryngology