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https://www.readbyqxmd.com/read/29346420/initial-acquisition-and-succession-of-the-cystic-fibrosis-lung-microbiome-is-associated-with-disease-progression-in-infants-and-preschool-children
#1
Marianne S Muhlebach, Bryan T Zorn, Charles R Esther, Joseph E Hatch, Conor P Murray, Lidija Turkovic, Sarath C Ranganathan, Richard C Boucher, Stephen M Stick, Matthew C Wolfgang
The cystic fibrosis (CF) lung microbiome has been studied in children and adults; however, little is known about its relationship to early disease progression. To better understand the relationship between the lung microbiome and early respiratory disease, we characterized the lower airways microbiome using bronchoalveolar lavage (BAL) samples obtained from clinically stable CF infants and preschoolers who underwent bronchoscopy and chest computed tomography (CT). Cross-sectional samples suggested a progression of the lower airways microbiome with age, beginning with relatively sterile airways in infancy...
January 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29344333/inverting-the-facing-the-viewer-bias-for-biological-motion-stimuli
#2
Séamas Weech, Nikolaus F Troje
Depth-ambiguous point-light walkers are most frequently seen as facing-the-viewer (FTV). It has been argued that the FTV bias depends on recognising the stimulus as a person. Accordingly, reducing the social relevance of biological motion by presenting stimuli upside down has been shown to reduce FTV bias. Here, we replicated the experiment that reported this finding and added stick figure walkers to the task in order to assess the effect of explicit shape information on facing bias for inverted figures. We measured the FTV bias for upright and inverted stick figure walkers and point-light walkers presented in different azimuth orientations...
January 2018: I-Perception
https://www.readbyqxmd.com/read/29344047/a-comparative-study-of-shift-work-effects-and-injuries-among-nurses-working-in-rotating-night-and-day-shifts-in-a-tertiary-care-hospital-of-north-india
#3
Anjana Verma, Jugal Kishore, Shobha Gusain
Background: Shift work can have an impact on the physical and psychological well-being of the healthcare worker, affecting patients as well as their own safety at the workplace. This study was conducted to compare the health outcomes and injuries, along with associated risk factors between the nurses working in rotating night shift (RNS) as compared to day shift (DS) only. Materials and Methods: It was a cross-sectional study conducted from June to November 2016 in a tertiary care hospital of Delhi...
January 2018: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/29343856/deep-ultraviolet-algan-aln-core-shell-multiple-quantum-wells-on-aln-nanorods-via-lithography-free-method
#4
Jinwan Kim, Uiho Choi, Jaedo Pyeon, Byeongchan So, Okhyun Nam
We report deep ultraviolet (UVC) emitting core-shell-type AlGaN/AlN multiple quantum wells (MQWs) on the AlN nanorods which are prepared by catalyst/lithography free process. The MQWs are grown on AlN nanorods on a sapphire substrate by polarity-selective epitaxy and etching (PSEE) using high-temperature metal organic chemical vapor deposition. The AlN nanorods prepared through PSEE have a low dislocation density because edge dislocations are bent toward neighboring N-polar AlN domains. The core-shell-type MQWs grown on AlN nanorods have three crystallographic orientations, and the final shape of the grown structure is explained by a ball-and-stick model...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29342304/introduction-of-standardised-tobacco-packaging-during-a-12-month-transition-period-findings-from-small-retailers-in-the-united-kingdom
#5
Nathan Critchlow, Martine Stead, Crawford Moodie, Douglas Eadie, Anne Marie MacKintosh
Introduction: Factory-made cigarettes (FMC) and roll-your-own (RYO) tobacco have had to be produced in standardised packaging since 20th May 2016 in the United Kingdom, with a minimum pack size of 20 sticks for FMC and 30 grams for RYO. Manufacturers and retailers were given a 12-month transition period. Methods: An observational study was conducted using monthly Electronic Point of Sale data from 500 small retailers in England, Scotland, and Wales, between May 2016 and May 2017...
January 12, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29341728/multislip-friction-with-a-single-ion
#6
Ian Counts, Dorian Gangloff, Alexei Bylinskii, Joonseok Hur, Rajibul Islam, Vladan Vuletić
A trapped ion transported along a periodic potential is studied as a paradigmatic nanocontact frictional interface. The combination of the periodic corrugation potential and a harmonic trapping potential creates a one-dimensional energy landscape with multiple local minima, corresponding to multistable stick-slip friction. We measure the probabilities of slipping to the various minima for various corrugations and transport velocities. The observed probabilities show that the multislip regime can be reached dynamically at smaller corrugations than would be possible statically, and can be described by an equilibrium Boltzmann model...
July 28, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29340434/structure-induced-switching-of-interpolymer-adhesion-at-a-solid-polymer-melt-interface
#7
Naisheng Jiang, Mani Sen, Wenduo Zeng, Zhizhao Chen, Justin M Cheung, Yuma Morimitsu, Maya K Endoh, Tadanori Koga, Masafumi Fukuto, Guangcui Yuan, Sushil K Satija, Jan-Michael Y Carrillo, Bobby G Sumpter
Here we report a link between the interfacial structure and adhesive property of homopolymer chains physically adsorbed (i.e., via physisorption) onto solids. Polyethylene oxide (PEO) was used as a model and two different chain conformations of the adsorbed polymer were created on silicon substrates via the well-established Guiselin's approach: "flattened chains" which lie flat on the solid and are densely packed, and "loosely adsorbed polymer chains" which form bridges jointing up nearby empty sites on the solid surface and cover the flattened chains...
January 17, 2018: Soft Matter
https://www.readbyqxmd.com/read/29337668/solving-manufacturing-problems-for-l-carnitine-l-tartrate-to-improve-the-likelihood-of-successful-product-scale-up
#8
Aliaa A Badawi, Mahmoud M Hegazy, Dina Louis, Mohammed A Eldegwy
L-carnitine-L-tartrate, a non-essential amino acid, is hygroscopic. This causes a problem in tablet production due to pronounced adhesion of tablets to punches. A 33 full factorial design was adopted to suggest a tablet formulation. Three adsorbents were suggested (Aerosil 200, Aerosil R972, talc) to reduce stickiness at three concentrations (1, 3 and 5 %), and three fillers (mannitol, Avicel PH 101, Dibasic calcium phosphate) were chosen to prepare 27 formulations. Micromeritic properties of formulations were studied, and tablets were prepared by wet granulation...
December 20, 2017: Acta Pharmaceutica
https://www.readbyqxmd.com/read/29335563/visualization-and-analysis-of-non-covalent-contacts-using-the-protein-contacts-atlas
#9
Melis Kayikci, A J Venkatakrishnan, James Scott-Brown, Charles N J Ravarani, Tilman Flock, M Madan Babu
Visualizations of biomolecular structures empower us to gain insights into biological functions, generate testable hypotheses, and communicate biological concepts. Typical visualizations (such as ball and stick) primarily depict covalent bonds. In contrast, non-covalent contacts between atoms, which govern normal physiology, pathogenesis, and drug action, are seldom visualized. We present the Protein Contacts Atlas, an interactive resource of non-covalent contacts from over 100,000 PDB crystal structures. We developed multiple representations for visualization and analysis of non-covalent contacts at different scales of organization: atoms, residues, secondary structure, subunits, and entire complexes...
January 15, 2018: Nature Structural & Molecular Biology
https://www.readbyqxmd.com/read/29334689/-stick-with-your-own-kind-or-hang-with-the-locals-implications-of-shoaling-strategy-for-tropical-reef-fish-on-a-range-expansion-frontline
#10
Shannen M Smith, Rebecca J Fox, David J Booth, Jennifer M Donelson
Range shifts of tropical marine species to temperate latitudes are predicted to increase as a consequence of climate change. To date, the research focus on climate-mediated range shifts has been predominately dealt with the physiological capacity of tropical species to cope with the thermal challenges imposed by temperate latitudes. Behavioural traits of individuals in the novel temperate environment have not previously been investigated, however, they are also likely to play a key role in determining the establishment success of individual species at the range-expansion forefront...
January 15, 2018: Global Change Biology
https://www.readbyqxmd.com/read/29332187/human-bite-injuries-to-the-head-and-neck-current-trends-and-management-protocols-in-england-and-wales
#11
Glyndwr W Jenkins, Robert Isaac, Shakir Mustafa
INTRODUCTION: Human bite injuries can be challenging in their presentation to the examining physician. In a study by Merchant et al., 18% of patients presenting with a human bite injury had suffered wounds to the head and neck region. Current trends in their initial management at presentation to emergency departments throughout England and Wales will be discussed in this paper. MATERIALS AND METHOD: A postal survey was sent out to 100 A&E lead clinicians. This was followed up by telephone enquiries to improve the response rate...
January 14, 2018: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29328686/three-dimensional-tracking-of-interfacial-hopping-diffusion
#12
Dapeng Wang, Haichao Wu, Daniel K Schwartz
Theoretical predictions have suggested that molecular motion at interfaces-which influences processes including heterogeneous catalysis, (bio)chemical sensing, lubrication and adhesion, and nanomaterial self-assembly-may be dominated by hypothetical "hops" through the adjacent liquid phase, where a diffusing molecule readsorbs after a given hop according to a probabilistic "sticking coefficient." Here, we use three-dimensional (3D) single-molecule tracking to explicitly visualize this process for human serum albumin at solid-liquid interfaces that exert varying electrostatic interactions on the biomacromolecule...
December 29, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29325832/the-pics-technique-a-novel-approach-for-residual-curvature-correction-during-penile-prosthesis-implantation-in-patients-with-severe-peyronie-s-disease-using-the-collagen-fleece-tachosil
#13
Georgios Hatzichristodoulou
BACKGROUND: Correction of residual curvature during inflatable penile prosthesis (IPP) implantation in patients with Peyronie's disease (PD) by plaque incision and grafting is a common approach. AIM: To present a novel technique for residual curvature correction during IPP implantation using collagen fleece (TachoSil, Baxter Healthcare Corp, Deerfield, IL, USA). METHODS: After the IPP (Titan Touch, Coloplast, Minneapolis, MN, USA) is placed, the implant is inflated maximally...
January 8, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29323773/direct-fiber-reinforced-interim-fixed-partial-dentures-six-year-survival-study
#14
Luciana Maria Goguta, Adrian Candea, Diana Lungeanu, Mirela Frandes, Anca Jivanescu
PURPOSE: Mechanical and optical studies of glass fiber composites have revealed great resistance and satisfactory bonds between the glass fibers and composite resins. This study aimed to evaluate the long-term survival of anterior and posterior direct glass fiber-reinforced composite (FRC) fixed partial dentures (FPD). MATERIALS AND METHODS: Twenty-three patients (9 men, 14 women) aged 18 to 67 received 23 d-FRC-FPDs. The frameworks of the FPDs were unidirectional pre-impregnated glass fibers (ever Stick C&B)...
January 11, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29323381/lifted-graphene-nanoribbons-on-gold-from-smooth-sliding-to-multiple-stick-slip-regimes
#15
L Gigli, N Manini, E Tosatti, R Guerra, A Vanossi
Graphene nanoribbons (GNRs) physisorbed on a Au(111) surface can be picked up, lifted at one end, and made to slide by means of the tip of an atomic-force microscope. The dynamic transition from smooth sliding to multiple stick-slip regimes, the pushing/pulling force asymmetry, the presence of pinning, and its origin are real frictional processes in a nutshell, in need of a theoretical description. To this purpose, we conduct classical simulations of frictional manipulations of a 30 nm-long GNR, one end of which is pushed or pulled horizontally while held at different heights above the Au surface...
January 11, 2018: Nanoscale
https://www.readbyqxmd.com/read/29322158/archaeological-evidence-for-pott-s-disease-on-historical-populations-tomb-05-at-the-roman-circus-maqbara-as-an-example-of-social-solidarity-toledo-spain
#16
Arturo Ruiz-Taboada, Isabel Molero Rodrigo
World societies can often be characterized by their attitude towards elderly and illness. It is well known that most cultures were concerned about those who were not able to produce and take care of themselves. This brings to the development of social processes that involve such individuals within the community, resulting in groups who stick together, and at last, ensuring the survival of the group. The contextualization of many of those social processes might be studied through Physical Anthropology and Paleopathology...
January 10, 2018: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
https://www.readbyqxmd.com/read/29320504/evaluation-of-the-practicability-and-virological-performance-of-finger-stick-whole-blood-hiv-self-testing-in-french-speaking-sub-saharan-africa
#17
Serge Tonen-Wolyec, Salomon Batina-Agasa, Jérémie Muwonga, Franck Fwamba N'kulu, Ralph-Sydney Mboumba Bouassa, Laurent Bélec
BACKGROUND: Opportunities for HIV testing could be enhanced by offering HIV self-testing (HIVST) in populations that fear stigma and discrimination when accessing conventional HIV counselling and testing in health care facilities. Field experience with HIVST has not yet been reported in French-speaking African countries. METHODS: The practicability of HIVST was assessed using the prototype the Exacto® Test HIV (Biosynex, Strasbourg, France) self-test in 322 adults living in Kisangani and Bunia, Democratic Republic of the Congo, according to World Health Organization's recommendations...
2018: PloS One
https://www.readbyqxmd.com/read/29319815/chemical-analysis-and-simulated-pyrolysis-of-tobacco-heating-system-2-2-compared-to-conventional-cigarettes
#18
Xiangyu Li, Yanbo Luo, Xingyi Jiang, Hongfei Zhang, Fengpeng Zhu, Shaodong Hu, Hongwei Hou, Qingyuan Hu, Yongqiang Pang
Introduction: Tobacco Heating System 2.2 (THS 2.2, marketed as iQOS), is a heat-not-burn (HNB) tobacco product that has been successfully introduced to global markets. Despite its expanding market, few independent and systematic researches into THS 2.2 have been carried out to date. Methods: We tested a comprehensive list of total particulate matter (TPM), water, tar, nicotine, propylene glycol, glycerin, carbon monoxide, volatile organic compounds, aromatic amines, hydrogen cyanide, ammonia, N-nitrosamines, phenol, and polycyclic aromatic hydrocarbon under both ISO and HCI regimes...
January 8, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29317904/a-change-management-approach-to-improving-safety-and-preventing-needle-stick-injuries
#19
Ann-Marie Aziz
Key drivers for preventing healthcare-associated infection (HCAI) include evidence-based practices and procedures that prevent infection. Among the current guidance for preventing HCAIs is evidence and mandatory requirements for reducing needle stick injuries (NSIs). This article highlights how John Kotter's model for change could help healthcare workers plan for successful and sustained deployment of needle safety devices (NSDs) and ultimately reduce the risk of a NSI.
September 2017: Journal of Infection Prevention
https://www.readbyqxmd.com/read/29314459/resveratrol-radical-repair-by-vitamin-c-at-the-micelle-water-interface-unexpected-reaction-rates-explained-by-ion-dipole-interactions
#20
Christoph Kerzig, Matthias Hoffmann, Martin Goez
Repair reactions of lipophilic phenoxy radicals by hydrophilic co-antioxidants at model membranes are important for understanding the factors that govern the interactions between radical scavengers in biological systems. By using near-UV photoionization, we have selectively generated the phenoxy radical of the famous antioxidant resveratrol inside anionic (SDS), cationic (DTAC), or neutral (TX-100) micelles, as well as in homogeneous aqueous solution, and have compared its repairs in these media by the water-soluble co-antioxidants ascorbic acid and ascorbate monoanion...
January 3, 2018: Chemistry: a European Journal
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