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https://www.readbyqxmd.com/read/28431226/the-impact-of-automatic-devices-for-capillary-blood-collection-on-efficiency-and-pain-response-in-newborns-a-randomized-controlled-trial
#1
G Sorrentino, M Fumagalli, S Milani, I Cortinovis, A Zorz, G Cavallaro, F Mosca, L Plevani
BACKGROUND: The heel stick is the method of choice in most neonatal units for capillary blood sampling, and it represents the most common event among all painful procedures performed on newborns. The type and design of heel stick device and the clinical procedure to collect a blood sample may have an impact on newborn pain response as well. OBJECTIVE: To compare the pain response and efficiency of different automated devices for capillary blood collection in newborns...
April 11, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28430006/evolutionary-changes-in-lamin-expression-in-the-vertebrate-lineage
#2
Reimer Stick, Annette Peter
The nuclear lamina is involved in fundamental nuclear functions and provides mechanical stability to the nucleus. Lamin filaments form a meshwork closely apposed to the inner nuclear membrane and a small fraction of lamins exist in the nuclear interior. Mutations in lamin genes cause severe hereditary diseases, the laminopathies. During vertebrate evolution the lamin protein family has expanded. While most vertebrate genomes contain four lamin genes, encoding the lamins A, B1, B2, and LIII, the majority of non-vertebrate genomes harbor only a single lamin gene...
April 21, 2017: Nucleus
https://www.readbyqxmd.com/read/28429112/testicular-cancer-patients-undergoing-cisplatin-based-chemotherapy-exhibit-temporary-olfactory-threshold-scores-changes
#3
Ute Walliczek-Dworschak, Volker Gudziol, Claudia Mitzschke, Michael Froehner, Thomas Hummel
Testicular cancer is the most frequent malignant disease in young males between 15 and 35 years. Platinum based chemotherapy regimen is the therapy of choice in advanced disease. This treatment has also adverse effects caused by the cytostatic active substances, such as olfactory dysfunctions. The aim of this study was, therefore, to monitor olfactory function of testicular cancer patients during and 6 months after chemotherapy. A total of 17 patients (mean age 31.06 ± 10.26 years), which underwent chemotherapy (mean 2...
April 20, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28426080/c-reactive-protein-and-interleukin-6-microfluidic-immunoassays-with-on-chip-pre-stored-reagents-and-centrifugo-pneumatic-liquid-control
#4
Y Zhao, G Czilwik, V Klein, K Mitsakakis, R Zengerle, N Paust
We present a fully automated centrifugal microfluidic method for particle based protein immunoassays. Stick-pack technology is employed for pre-storage and release of liquid reagents. Quantitative layout of centrifugo-pneumatic particle handling, including timed valving, switching and pumping is assisted by network simulations. The automation is exclusively controlled by the spinning frequency and does not require any additional means. New centrifugal microfluidic process chains are developed in order to sequentially supply wash buffer based on frequency dependent stick-pack opening and pneumatic pumping to perform two washing steps from one stored wash buffer; pre-store and re-suspend functionalized microparticles on a disk; and switch between the path of the waste fluid and the path of the substrate reaction product with 100% efficiency...
April 20, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28425745/when-good-is-stickier-than-bad-understanding-gain-loss-asymmetries-in-sequential-framing-effects
#5
Jehan Sparks, Alison Ledgerwood
Considerable research has demonstrated the power of the current positive or negative frame to shape people's current judgments. But humans must often learn about positive and negative information as they encounter that information sequentially over time. It is therefore crucial to consider the potential importance of sequencing when developing an understanding of how humans think about valenced information. Indeed, recent work looking at sequentially encountered frames suggests that some frames can linger outside the context in which they are first encountered, sticking in the mind so that subsequent frames have a muted effect...
April 20, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28424253/identification-of-acute-hiv-1-infection-by-hologic-aptima-hiv-1-rna-qualitative-assay
#6
Mark M Manak, Leigh Anne Eller, Jennifer Malia, Linda L Jagodzinski, Rapee Trichavaroj, Joseph Oundo, Cornelia Lueer, Fatim Cham, Mark de Souza, Nelson L Michael, Merlin L Robb, Sheila A Peel
The Hologic Aptima HIV-1 Qualitative RNA assay was used in a rigorous screening approach designed to identify individuals at the earliest stage of HIV-1 infection for enrollment into subsequent studies of cellular and viral events in early infection (RV217/Early Capture HIV Cohort - ECHO Study). Volunteers at high risk of HIV-1 infection were recruited from study sites in Thailand, Tanzania, Uganda and Kenya with high HIV-1 prevalence rates among the populations examined. Small volume blood samples were collected by finger-stick at twice-weekly intervals and tested by Aptima...
April 19, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28423278/shapes-of-splattered-drops
#7
Sri Vallabha Deevi, Nachiketa Janardan, Mahesh V Panchagnula
Drops that impact and stick to a surface (splattered drops) commonly show non- circular triple lines. Physical or chemical defects on the surface are known to pin the triple line in this static metastable state. We report an experimental study to relate the defect distribution on a surface to the triple line microstructure of such drops. Triple lines of an ensemble of splattered drops have been imaged on a range of surfaces varying in wetting properties. Local contact angles have been calculated and the microscale pinning force distribution estimated...
April 19, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28422690/doubly-nonparametric-sparse-nonnegative-matrix-factorization-based-on-dependent-indian-buffet-processes
#8
Junyu Xuan, Jie Lu, Guangquan Zhang, Richard Yi Da Xu, Xiangfeng Luo
Sparse nonnegative matrix factorization (SNMF) aims to factorize a data matrix into two optimized nonnegative sparse factor matrices, which could benefit many tasks, such as document-word co-clustering. However, the traditional SNMF typically assumes the number of latent factors (i.e., dimensionality of the factor matrices) to be fixed. This assumption makes it inflexible in practice. In this paper, we propose a doubly sparse nonparametric NMF framework to mitigate this issue by using dependent Indian buffet processes (dIBP)...
April 12, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28422602/does-bonding-approach-influence-the-bond-strength-of-universal-adhesive-to-dentin-of-primary-teeth
#9
Tathiane Larissa Lenzi, Fabio Zovico Maxnuck Soares, Rachel de Oliveira Rocha
OBJECTIVE: To evaluate the effect of bonding strategy on microtensile bond strength (μTBS) of a new universal adhesive system to primary tooth dentin. STUDY DESIGN: Flat dentin surfaces from 25 primary molars were assigned to 5 groups according to the adhesive and bonding approach: Adper Single Bond 2 (two-step etch-and-rinse adhesive) and Clearfil SE Bond (two-step self-etch system), as controls; Scotchbond Universal Adhesive-self-etch, dry or wet-bonding etch-and-rinse strategies...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28422196/boundary-layer-friction-of-solvate-ionic-liquids-as-a-function-of-potential
#10
Hua Li, Mark W Rutland, Masayoshi Watanabe, Rob Atkin
Atomic force microscopy (AFM) has been used to investigate the potential dependent boundary layer friction at solvate ionic liquid (SIL)-highly ordered pyrolytic graphite (HOPG) and SIL-Au(111) interfaces. Friction trace and retrace loops of lithium tetraglyme bis(trifluoromethylsulfonyl)amide (Li(G4) TFSI) at HOPG present clearer stick-slip events at negative potentials than at positive potentials, indicating that a Li(+) cation layer adsorbed to the HOPG lattice at negative potentials which enhances stick-slip events...
April 19, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28421029/a-historical-view-of-motion-sickness-a-plague-at-sea-and-on-land-also-with-military-impact
#11
Doreen Huppert, Judy Benson, Thomas Brandt
Seasickness and its triggers, symptoms, and preventive measures were well known in antiquity. This chapter is based on an analysis of descriptions of motion sickness, in particular seasickness, in ancient Greek, Roman, and Chinese literature. A systematic search was made from the Greek period beginning with Homer in 800 BC to the late Roman period and ending with Aetios Amidenos in 600 AD, as well as in the Chinese medical classics dating from around 300 AD. Major aspects are the following: body movements caused by waves were identified in all cultures as the critical stimuli...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28419471/spectral-analysis-of-the-stick-slip-phenomenon-in-oral-tribological-texture-evaluation
#12
Solange Sanahuja, Rutuja Upadhyay, Heiko Briesen, Jianshe Chen
"Oral" tribology has become a new paradigm in food texture studies to understand complex texture attributes, such as creaminess, oiliness, and astringency, which could not be successfully characterized by traditional texture analysis nor by rheology. Stick-slip effects resulting from intermittent sliding motion during kinetic friction of oral mucosa could constitute an additional determining factor of sensory perception where traditional friction coefficient values and their Stribeck regimes fail in predicting different lubricant (food bolus and saliva) behaviors...
March 28, 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/28416710/compliance-with-uruguay-s-single-presentation-requirement
#13
Teresa DeAtley, Eduardo Bianco, Kevin Welding, Joanna E Cohen
INTRODUCTION: Tobacco companies vary pack colours, designs, descriptors, flavours and brand names on cigarette packs to target a multitude of consumers. These different brand variants can falsely imply that some brand variants are less harmful than others. Uruguay is the only country that requires cigarette companies to adhere to a single presentation (one brand variant) per brand family. METHODS: An existing, systematic pack purchasing protocol was adapted for data collection...
April 17, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28416172/epidemiology-of-ebolavirus-disease-evd-and-occupational-evd-in-health-care-workers-in-sub-saharan-africa-need-for-strengthened-public-health-preparedness
#14
REVIEW
Nlandu Roger Ngatu, Ntumba Jean-Marie Kayembe, Elayne Kornblatt Phillips, Joa Okech-Ojony, Masika Patou-Musumari, Mukunda Gaspard-Kibukusa, Ndona Madone-Mandina, Mabasi Godefroid-Mayala, Lubogo Mutaawe, Casimir Manzengo, Dimosi Roger-Wumba, Sayumi Nojima
Ebolavirus disease (EVD) is a severe contagious disease in humans, and health care workers (HCW) are at risk of infection when caring for EVD patients. This paper highlights the epidemiologic profile of EVD and its impact on the health care workforce in Africa. A documentary study was conducted which consisted of a review of available literature regarding the epidemiology of EVD, occupational EVD (OEVD), and work safety issues in Sub-Saharan Africa; the literature findings are enriched by field experiences from the authors...
April 13, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28414516/effects-of-having-preterm-infants-smell-amniotic-fluid-mother-s-milk-and-mother-s-odor-during-heel-stick-procedure-on-pain-physiological-parameters-and-crying-duration
#15
Dilek Küçük Alemdar, Funda Kardaş Özdemir
OBJECTIVE: The study aims to assess effects of having preterm infants smell amniotic fluid, mother's milk, and mother's odor during heel stick procedure on pain, physiological parameters, and crying duration. MATERIALS AND METHODS: The study was a randomized controlled experimental research. The population of the study was made up of preterm infants receiving treatment and care at a neonatal intensive care unit, where the study was conducted between January 2015 and March 2016...
April 17, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28413909/sticking-to-the-romantic-script-an-examination-of-love-life-scripts-stories-and%C3%A2-self-reports-of-normality
#16
William L Dunlop, Grace E Hanley, Tara P McCoy, Nicole Harake
Life scripts represent cultural expectations regarding the events in the prototypical life whereas life stories represent narrative constructions of the events occurring in individuals' own lives. In Study 1, we generated an outline of the love life script and a list of the self-definitional events individuals tend to associate with their own love lives. Participants were prompted to produce and rate seven important events in the prototypical love life and several significant moments from their own love lives...
April 16, 2017: Memory
https://www.readbyqxmd.com/read/28412733/prevention-of-tumor-seeding-during-needle-biopsy-by-chemotherapeutic-releasing-gelatin-sticks
#17
Ren-Yuan Bai, Verena Staedtke, Xuewei Xia, Gregory J Riggins
Needle biopsy is an indispensable diagnostic tool in obtaining tumor tissue for diagnostic examination. Tumor cell seeding in the needle track during percutaneous needle biopsies has been reported for various types of cancers. The mechanical force of the biopsy both directly displaces the malignant cells and causes bleeding and fluid movement that can further disseminate cells. To prevent the risk of tumor cell seeding during biopsy, we developed a gelatin stick loaded with chemotherapeutics such as doxorubicin (DXR) that was inserted into the biopsy canal...
February 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28408490/atomic-force-microscopy-of-virus-shells
#18
REVIEW
Francisco Moreno-Madrid, Natalia Martín-González, Aida Llauró, Alvaro Ortega-Esteban, Mercedes Hernando-Pérez, Trevor Douglas, Iwan A T Schaap, Pedro J de Pablo
Microscopes are used to characterize small objects with the help of probes that interact with the specimen, such as photons and electrons in optical and electron microscopies, respectively. In atomic force microscopy (AFM), the probe is a nanometric tip located at the end of a microcantilever which palpates the specimen under study just as a blind person manages a walking stick. In this way, AFM allows obtaining nanometric resolution images of individual protein shells, such as viruses, in a liquid milieu. Beyond imaging, AFM also enables not only the manipulation of single protein cages, but also the characterization of every physicochemical property capable of inducing any measurable mechanical perturbation to the microcantilever that holds the tip...
April 15, 2017: Biochemical Society Transactions
https://www.readbyqxmd.com/read/28408479/how-do-they-stick-together-bacterial-adhesins-implicated-in-the-binding-of-bacteria-to-the-human-gastrointestinal-mucins
#19
REVIEW
Bélinda Ringot-Destrez, Nicolas Kalach, Adriana Mihalache, Pierre Gosset, Jean-Claude Michalski, Renaud Léonard, Catherine Robbe-Masselot
The gastrointestinal mucosal surface is the primary interface between internal host tissues and the vast microbiota. Mucins, key components of mucus, are high-molecular-weight glycoproteins characterized by the presence of many O-linked oligosaccharides to the core polypeptide. They play many biological functions, helping to maintain cellular homeostasis and to establish symbiotic relationships with complex microbiota. Mucin O-glycans exhibit a huge variety of peripheral sequences implicated in the binding of bacteria to the mucosal tissues, thereby playing a key role in the selection of specific species and in the tissue tropism displayed by commensal and pathogenic bacteria...
April 15, 2017: Biochemical Society Transactions
https://www.readbyqxmd.com/read/28407708/application-of-lateral-approach-for-the-removal-of-migrated-interbody-cage-taphole-and-fixing-technique
#20
Jae Sung Eom, Ikchan Jeon, Sang Woo Kim
When a revision surgery related with removal of failed interbody cage is required, going through the previous passage can lead to a higher risk of neurological deficits or incidental dural injuries. Recently, the lateral approach has become a popular method instead of the conventional anterior or posterior approaches. The lateral approach is also useful method to remove failed interbody cage previously placed and re-do interbody fusion with lower risks compared to revision surgery via previous passage. However, there is still some difficulty in retrieving the interbody cage from the intervertebral space because of no spacious passage, subsidence, and uncontrolled movable cage...
March 2017: Korean Journal of Spine
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