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https://www.readbyqxmd.com/read/28227981/assessment-of-sedation-analgesia-by-means-of-poincare%C3%AC-analysis-of-the-electroencephalogram
#1
Jose D Bolanos, Montserrat Vallverdu, Pere Caminal, Daniel F Valencia, Xavi Borrat, Pedro L Gambus, Jose F Valencia, Jose D Bolanos, Montserrat Vallverdu, Pere Caminal, Daniel F Valencia, Xavi Borrat, Pedro L Gambus, Jose F Valencia, Jose D Bolanos, Xavi Borrat, Jose F Valencia, Montserrat Vallverdu, Pere Caminal, Pedro L Gambus, Daniel F Valencia
Monitoring the levels of sedation-analgesia may be helpful for managing patient stress on minimally invasive medical procedures. Monitors based on EEG analysis and designed to assess general anesthesia cannot distinguish reliably between a light and deep sedation. In this work, the Poincaré plot is used as a nonlinear technique applied to EEG signals in order to characterize the levels of sedation-analgesia, according to observed categorical responses that were evaluated by means of Ramsay Sedation Scale (RSS)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226925/human-physical-condition-rf-sensing-at-thz-range
#2
A Vorobyov, E Daskalaki, C Hennemann, J-D Decotignie, A Vorobyov, E Daskalaki, C Hennemann, J-D Decotignie, E Daskalaki, C Hennemann, A Vorobyov, J-D Decotignie
The skin response to high radio frequency has been associated with the human physical condition and most prominently with the stress. The objective of this study is to investigate the possibility to detect mental and light physical stress through the measurement of skin reflectance in the mm-wave/sub-THz band. Two frequency bands have been considered, 75-110 GHz (Band-I) and 325-500 GHz (Band-II), while the measurements have been performed in the three different locations, the arm, the dorsal side of the hand and the fingertip...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28220700/probing-the-intrinsic-thermal-and-photochemical-stability-of-hybrid-and-inorganic-lead-halide-perovskites
#3
Azat F Akbulatov, Sergey Yurevich Luchkin, Lyubov A Frolova, Nadezhda N Dremova, Ivan S Zhidkov, Kirill L Gerasimov, Denis V Anokhin, Ernst Z Kurmaev, Keith J Stevenson, Pavel A Troshin
We report a careful and systematic study of the thermal and photochemical degradation of a series of complex haloplumbates APbX3 (X=I, Br) with hybrid organic (A+= CH3NH3) and inorganic (A+=Cs+) cations under anoxic conditions (i.e., without exposure to oxygen and moisture by testing in an inert glove box environment). We show that the most common hybrid materials (e.g. MAPbI3) are intrinsically unstable with respect to the heat- and light-induced stress and, therefore, can hardly sustain the real solar cell operation conditions...
February 21, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28217553/effect-of-vestibular-stimulation-on-auditory-and-visual-reaction-time-in-relation-to-stress
#4
Archana Rajagopalan, Sai Sailesh Kumar, Joseph Kurien Mukkadan
The present study was undertaken to provide scientific evidence and for beneficial effects of vestibular stimulation for the management of stress-induced changes in auditory and visual reaction time (RT). A total of 240 healthy college students of the age group of 18-24 of either gender were a part of this research after obtaining written consent from them. RT for right and left response was measured for two auditory stimuli (low and high pitch) and visual stimuli (red and green) were recorded. A significant decrease in the visual RT for green light and red light was observed and stress-induced changes was effectively prevented followed by vestibular stimulation...
January 2017: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/28211478/ecology-and-genetics-affect-relative-invasion-success-of-two-echium-species-in-southern-australia
#5
Xiaocheng Zhu, Paul A Weston, Dominik Skoneczny, David Gopurenko, Lucie Meyer, Brendan J Lepschi, Ragan M Callaway, Geoff M Gurr, Leslie A Weston
Echium plantagineum and E. vulgare are congeneric exotics first introduced to Australia in the early 1800 s. There, E. plantagineum is now highly invasive, whereas E. vulgare has a limited distribution. Studies were conducted to evaluate distribution, ecology, genetics and secondary chemistry to shed light on factors associated with their respective invasive success. When sampled across geographically diverse locales, E. plantagineum was widespread and exhibited a small genome size (1 C = 0.34 pg), an annual life cycle, and greater genetic diversity as assessed by DNA sequence analysis...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28203242/sunlight-modulates-fruit-metabolic-profile-and-shapes-the-spatial-pattern-of-compound-accumulation-within-the-grape-cluster
#6
Noam Reshef, Natasha Walbaum, Nurit Agam, Aaron Fait
Vineyards are characterized by their large spatial variability of solar irradiance (SI) and temperature, known to effectively modulate grape metabolism. To explore the role of sunlight in shaping fruit composition and cluster uniformity, we studied the spatial pattern of incoming irradiance, fruit temperature and metabolic profile within individual grape clusters under three levels of sunlight exposure. The experiment was conducted in a vineyard of Cabernet Sauvignon cv. located in the Negev Highlands, Israel, where excess SI and midday temperatures are known to degrade grape quality...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28192592/an-algorithm-to-predict-the-biomechanical-stiffening-effect-in-corneal-cross-linking
#7
Sabine Kling, Farhad Hafezi
PURPOSE: To develop an algorithm to predict the stiffening effect of CXL and to verify the accuracy with results obtained from experimental measurements. METHODS: The algorithm considers different variables: the reaction kinetics of riboflavin diffusion and riboflavin photodegradation to determine the effective riboflavin concentration in different stromal layers; the oxygen diffusion and ultraviolet (UV) absorption to determine the amount of reactive oxygen species as a function of time and stromal depth...
February 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28188782/lipid-and-carotenoid-cooperation-driven-adaptation-to-light-and-temperature-stress-in-synechocystis-sp-pcc6803
#8
Tomas Zakar, Eva Herman, Sindhujaa Vajravel, Laszlo Kovacs, Jana Knoppová, Josef Komenda, Ildiko Domonkos, Mihaly Kis, Zoltan Gombos, Hajnalka Laczko-Dobos
Polyunsaturated lipids are important components of photosynthetic membranes. Xanthophylls are the main photoprotective agents, can assist in protection against light stress, and are crucial in the recovery from photoinhibition. We generated the xanthophyll- and polyunsaturated lipid-deficient ROAD mutant of Synechocystis sp. PCC6803 (Synechocystis) in order to study the little-known cooperative effects of lipids and carotenoids (Cars). Electron microscopic investigations confirmed that in the absence of xanthophylls the S-layer of the cellular envelope is missing...
February 8, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28188205/metagenomic-and-metatranscriptomic-analyses-reveal-structure-and-dynamics-of-a-dechlorinating-community-containing-dehalococcoides-mccartyi-and-corrinoid-providing-microorganisms-under-cobalamin-limited-condition
#9
Yujie Men, Ke Yu, Jacob Bælum, Ying Gao, Julien Tremblay, Emmanuel Prestat, Ben Stenuit, Susannah G Tringe, Janet Jansson, Tong Zhang, Lisa Alvarez-Cohen
The aim of this study is to obtain a systems level understanding of the interactions between Dehalococcoides and corrinoid-supplying microorganisms by analyzing community structures and functional compositions, activities and dynamics in trichloroethene (TCE) - dechlorinating enrichments. Metagenomes and metatranscriptomes of the dechlorinating enrichments with and without exogenous cobalamin were compared. Seven putative draft genomes were binned from the metagenomes. At an early stage (2 d), more transcripts of genes in the Veillonellaceae bin-genome were detected in the metatranscriptome of the enrichment with exogenous cobalamin compared to the one without cobalamin addition...
February 10, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28187286/endogenous-dna-damage-as-a-source-of-genomic-instability-in-cancer
#10
REVIEW
Anthony Tubbs, André Nussenzweig
Genome instability, defined as higher than normal rates of mutation, is a double-edged sword. As a source of genetic diversity and natural selection, mutations are beneficial for evolution. On the other hand, genomic instability can have catastrophic consequences for age-related diseases such as cancer. Mutations arise either from inactivation of DNA repair pathways or in a repair-competent background due to genotoxic stress from celluar processes such as transcription and replication that overwhelm high-fidelity DNA repair...
February 9, 2017: Cell
https://www.readbyqxmd.com/read/28184008/importance-of-fluctuations-in-light-on-plant-photosynthetic-acclimation
#11
Silvere Rm Vialet-Chabrand, Jack Sa Matthews, Andrew Simkin, Christine A Raines, Tracy Lawson
Acclimation of plants to light has been studied extensively, yet little is known about the effect of dynamic fluctuations in light on plant phenotype and acclimatory responses. We mimicked natural fluctuations in light over a diurnal period to examine the effect on photosynthetic processes and growth of Arabidopsis thaliana. High and low light intensities, delivered via a realistic dynamic fluctuating or square wave pattern were used to grow and assess plants. Plants subjected to square wave light had thicker leaves and greater photosynthetic capacity compared with fluctuating light grown plants...
February 9, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28182317/impact-of-light-intensity-and-quality-on-chromatophore-and-nuclear-gene-expression-in-paulinella-chromatophora-an-amoeba-with-nascent-photosynthetic-organelles
#12
Ru Zhang, Eva C M Nowack, Dana C Price, Debashish Bhattacharya, Arthur R Grossman
Plastid evolution has been attributed to a single primary endosymbiotic event that occurred ~1.6 BYA in which a cyanobacterium was engulfed and retained by a eukaryotic cell, although early steps in plastid integration are poorly understood. The photosynthetic amoeba Paulinella chromatophora represents a unique model to study plastid evolution because it contains cyanobacterium-derived photosynthetic organelles termed "chromatophores" that originated relatively recently (0.06-0.14 BYA). The chromatophore genome is ~1/3 the size of the genome of closely related cyanobacteria, but 10-fold larger than most plastid genomes...
February 9, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28181829/marked-augmentation-of-plga-nanoparticle-induced-metabolically-beneficial-impact-of-%C3%AE-oryzanol-on-fuel-dyshomeostasis-in-genetically-obese-diabetic-ob-ob-mice
#13
Chisayo Kozuka, Chigusa Shimizu-Okabe, Chitoshi Takayama, Kaku Nakano, Hidetaka Morinaga, Ayano Kinjo, Kotaro Fukuda, Asuka Kamei, Akihito Yasuoka, Takashi Kondo, Keiko Abe, Kensuke Egashira, Hiroaki Masuzaki
Our previous works demonstrated that brown rice-specific bioactive substance, γ-oryzanol acts as a chaperone, attenuates exaggerated endoplasmic reticulum (ER) stress in brain hypothalamus and pancreatic islets, thereby ameliorating metabolic derangement in high fat diet (HFD)-induced obese diabetic mice. However, extremely low absorption efficiency from intestine of γ-oryzanol is a tough obstacle for the clinical application. Therefore, in this study, to overcome extremely low bioavailability of γ-oryzanol with super-high lipophilicity, we encapsulated γ-oryzanol in polymer poly (DL-lactide-co-glycolide) (PLGA) nanoparticles (Nano-Orz), and evaluated its metabolically beneficial impact in genetically obese-diabetic ob/ob mice, the best-known severest diabetic model in mice...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28181809/two-fold-anisotropy-governs-morphological-evolution-and-stress-generation-in-sodiated-black-phosphorous-for-sodium-ion-batteries
#14
Tianwu Chen, Peng Zhao, Xu Guo, Sulin Zhang
Phosphorous represents a promising anode material for sodium ion batteries owing to its extremely high theoretical capacity. Recent in-situ transmission electron microscopy studies evidenced anisotropic swelling in sodiated black phosphorous, which may find an origin from the two intrinsic anisotropic properties inherent to the layered structure of black phosphorous: sodium diffusional directionality and insertion strain anisotropy. To understand the morphological evolution and stress generation in sodiated black phosphorous, we develop a chemo-mechanical model by incorporating the intrinsic anisotropic properties into the large elasto-plastic deformation...
February 9, 2017: Nano Letters
https://www.readbyqxmd.com/read/28181798/shape-morphing-materials-from-stimuli-responsive-hydrogel-hybrids
#15
Seog-Jin Jeon, Adam W Hauser, Ryan C Hayward
The formation of well-defined and functional three-dimensional (3D) structures by buckling of thin sheets subjected to spatially nonuniform stresses is common in biological morphogenesis and has become a subject of great interest in synthetic systems, as such programmable shape-morphing materials hold promise in areas including drug delivery, biomedical devices, soft robotics, and biomimetic systems. Given their ability to undergo large changes in swelling in response to a wide variety of stimuli, hydrogels have naturally emerged as a key type of material in this field...
February 9, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28181400/high-power-actuation-from-molecular-photoswitches-in-enantiomerically-paired-soft-springs
#16
Sarah J Aßhoff, Federico Lancia, Supitchaya Iamsaard, Benjamin Matt, Tibor Kudernac, Stephen P Fletcher, Nathalie Katsonis
Motion in plants often relies on dynamic helical systems as seen in coiling tendrils, spasmoneme springs, and the opening of chiral seedpods. Developing nanotechnology that would allow molecular-level phenomena to drive such movements in artificial systems remains a scientific challenge. Herein, we describe a soft device that uses nanoscale information to mimic seedpod opening. The system exploits a fundamental mechanism of stimuli-responsive deformation in plants, namely that inflexible elements with specific orientations are integrated into a stimuli-responsive matrix...
February 9, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28178571/genome-wide-identification-and-analysis-of-biotic-and-abiotic-stress-regulation-of-small-heat-shock-protein-hsp20-family-genes-in-bread-wheat
#17
Senthilkumar K Muthusamy, Monika Dalal, Viswanathan Chinnusamy, Kailash C Bansal
Small Heat Shock Proteins (sHSPs)/HSP20 are molecular chaperones that protect plants by preventing protein aggregation during abiotic stress conditions, especially heat stress. Due to global climate change, high temperature is emerging as a major threat to wheat productivity. Thus, the identification of HSP20 and analysis of HSP transcriptional regulation under different abiotic stresses in wheat would help in understanding the role of these proteins in abiotic stress tolerance. We used sequences of known rice and Arabidopsis HSP20 HMM profiles as queries against publicly available wheat genome and wheat full length cDNA databases (TriFLDB) to identify the respective orthologues from wheat...
January 22, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28178380/pre-ischemia-melatonin-treatment-alleviated-acute-neuronal-injury-after-ischemic-stroke-by-inhibiting-er-stress-dependent-autophagy-via-perk-and-ire1-signalings
#18
Dayun Feng, Bao Wang, Lei Wang, Neeta Abraham, Kai Tao, Lu Huang, Wei Shi, Yushu Dong, Yan Qu
Melatonin has demonstrated a potential protective effect in central nervous system. Thus, it is interesting to determine whether pre-ischemia melatonin administration could protect against cerebral ischemia/reperfusion (IR) related injury and the underlying molecular mechanisms. In this study, we revealed that IR injury significantly activated endoplasmic reticulum (ER) stress and autophagy in a middle cerebral artery occlusion (MCAO) mouse model. Pre-ischemia melatonin treatment was able to attenuate IR-induced ER stress and autophagy...
February 8, 2017: Journal of Pineal Research
https://www.readbyqxmd.com/read/28176042/acclimation-of-shade-tolerant-and-light-resistant-tradescantia-species-to-growth-light-chlorophyll-a-fluorescence-electron-transport-and-xanthophyll-content
#19
Vladimir I Mishanin, Boris V Trubitsin, Svetlana V Patsaeva, Vasily V Ptushenko, Alexei E Solovchenko, Alexander N Tikhonov
In this study, we have compared the photosynthetic characteristics of two contrasting species of Tradescantia plants, T. fluminensis (shade-tolerant species), and T. sillamontana (light-resistant species), grown under the low light (LL, 50-125 µmol photons m(-2) s(-1)) or high light (HL, 875-1000 µmol photons m(-2) s(-1)) conditions during their entire growth period. For monitoring the functional state of photosynthetic apparatus (PSA), we measured chlorophyll (Chl) a emission fluorescence spectra and kinetics of light-induced changes in the heights of fluorescence peaks at 685 and 740 nm (F 685 and F 740)...
February 8, 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/28173981/leveraging-natural-variance-towards-enhanced-understanding-of-phytochemical-sunscreens
#20
REVIEW
Takayuki Tohge, Alisdair R Fernie
The dependency of plants on sunlight renders exposure to UV a constant hazard. Light of this wavelength is damaging to proteins, RNA, and DNA, with damage to the latter resulting in a high mutagenic potential. To acclimate to environmental changes in light wavelengths and intensity, plants accumulate the production of UV-B-protectant phytochemicals, such as flavonoids and vitamins. Here, we review current and emerging knowledge concerning the biochemical response of plants to UV-B exposure. We additionally outline our opinion that the adoption of broad natural variance represents a powerful strategy by which to identify both novel UV-B-relevant metabolites and the genes regulating their abundance...
February 4, 2017: Trends in Plant Science
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