Yuanjia Zhu, Shin Yajima, Matthew H Park, Akshay Venkatesh, Charles J Stark, Nicholas A Tran, Sabrina K Walsh, Sidarth Ethiraj, Robert J Wilkerson, Luca E Lin, Seung Hyun Lee, Kate Y Gates, Justin D Arthur, Sam W Baker, Danielle M Mullis, Catherine A Wu, Shun Harima, Bipul Pokhrel, Dominique Resuello, Hunter Bergamasco, Matthew A Wu, Basil M Baccouche, Pearly K Pandya, Stefan Elde, Hanjay Wang, Y Joseph Woo
BACKGROUND: Various mitral repair techniques have been described. Though these repair techniques can be highly effective when performed correctly in suitable patients, limited quantitative biomechanical data are available. Validation and thorough biomechanical evaluation of these repair techniques from translational large animal in vivo studies in a standardized, translatable fashion are lacking. We sought to evaluate and validate biomechanical differences among different mitral repair techniques and further optimize repair operations using a large animal mitral valve prolapse model...
April 2024: Circulation. Cardiovascular Interventions