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Valve durability

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https://www.readbyqxmd.com/read/29790209/subclinical-leaflet-thrombosis-following-transcatheter-aortic-valve-replacement
#1
Somsupha Kanjanauthai, Luigi Pirelli, Nikhil Nalluri, Chad A Kliger
Since the inception of transcatheter aortic valve replacement (TAVR), there have been significant reductions in complications due to improvements of transcatheter heart valve (THV) designs and technologies. Given expanding TAVR applications, reducing complications further and better understanding THV durability has become a focus within the structural heart space. Recently, dedicated cardiac computed tomographic angiography (CTA) performed at 1 month post-TAVR has identified subclinical leaflet thrombosis (SLT), with rates as high as 40%...
May 23, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29788322/outcomes-and-risk-factors-associated-with-tricuspid-valve-repair-in-children-with-hypoplastic-left-heart-syndrome
#2
Bahaaldin Alsoufi, Raina Sinha, Courtney McCracken, Janet Figueroa, Firat Altin, Kirk Kanter
OBJECTIVES: Tricuspid valve (TV) competence is important for successful palliation of hypoplastic left heart syndrome (HLHS). We report our experience with TV repair in HLHS patients with a focus on TV and right ventricular (RV) function and associated clinical outcomes. METHODS: From 2002 to 2012, 219 neonates with HLHS underwent the Norwood operation. Thirty patients who underwent TV repair at various stages comprised our current series cohort. Echocardiographic and clinical data were reviewed to determine the effectiveness of TV repair and outcomes of the patients...
May 19, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29781182/valve-in-valve-transcatheter-aortic-valve-implantation-viv-tavi-versus-redo-surgical-aortic-valve-replacement-redo-savr-a-systematic-review-and-meta-analysis
#3
REVIEW
Nikhil Nalluri, Varunsiri Atti, Abdullah B Munir, Boutros Karam, Nileshkumar J Patel, Varun Kumar, Praveen Vemula, Susruth Edla, Deepak Asti, Amrutha Paturu, Sriramya Gayam, Jonathan Spagnola, Emad Barsoum, Gregory A Maniatis, Frank Tamburrino, Ruben Kandov, James Lafferty, Chad Kliger
BACKGROUND: Bioprosthetic (BP) valves have been increasingly used for aortic valve replacement over the last decade. Due to their limited durability, patients presenting with failed BP valves are rising. Valve in Valve - Transcatheter Aortic Valve Implantation (ViV-TAVI) emerged as an alternative to the gold standard redo-Surgical Aortic Valve Replacement (redo-SAVR). However, the utility of ViV-TAVI is poorly understood. METHODS: A systematic electronic search of the scientific literature was done in PubMed, EMBASE, SCOPUS, Google Scholar, and ClinicalTrials...
May 20, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29771343/do-surgical-modifications-at-the-annular-level-during-the-ross-procedure-negatively-influence-the-structural-and-functional-durability-of-the-autograft
#4
Anja Lögers, Barbara Rosser, Burkhardt Seifert, Oliver Kretschmar, Michael Hübler, René Prêtre, Lotfi Ben Mime
OBJECTIVES: Do surgical modifications at the annular level (e.g. the modified Ross-Konno procedure or reduction plasty) influence the structure and function of the Ross autograft at the mid-term follow-up? METHODS: From June 2001 to July 2009, 49 patients (37 men and 12 women), mean age 10.5 ± 5.7 years (range 2 weeks to 17.8 years), underwent Ross operations. Twenty-one patients underwent additional aortic annulus reduction plasty and 9 patients a modified Ross-Konno procedure...
May 15, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29762921/long-term-up-to-21-years-follow-up-after-biological-and-mechanical-aortic-valve-replacement-in-younger-patients
#5
Stanislav Tsvelodub, Barbara Pieper, Sina Stock, Hans-Hinrich Sievers, Doreen Richardt
BACKGROUND: Despite the limited durability of biological aortic valves, increasing numbers of younger patients are choosing to receive them, due mainly to the lack of a need for permanent anticoagulation. Few data exist, however, regarding the outcomes of valve replacement in patients aged <55 years, and additional data are required in this patient population. METHODS: Between 1993 and 2014, at the authors' institution, a total of 448 patients (237 males, 101 females; mean age 45...
September 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29762920/outcomes-of-a-new-generation-stentless-aortic-valve-a-single-center-experience-with-251-consecutive-implants
#6
Guglielmo Stefanelli, Fabrizio Pirro, Giuseppe Danniballe, Alina Olaru, Marco Meli, Luca Weltert
BACKGROUND: The study aim was to investigate the hemodynamic behavior over time and ease of implant and durability of the Sorin Pericarbon Freedom (SPF)® stentless pericardial aortic xenograft. METHODS: Between March 2003 and April 2010, a total of 251 consecutive, non-selected patients (mean age 70.1 years; range: 17-89 years; 17.1% aged >80 years) received a SPF bioprosthesis as an aortic valve substitute at the authors' institution. All implantations were performed by a single surgeon using a classical, double-line, subcoronary implant technique...
September 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29759737/long-term-outcome-of-cryopreserved-allograft-for-aortic-valve-replacement
#7
Francesco Nappi, Antonio Nenna, Tommasangelo Petitti, Cristiano Spadaccio, Ivancarmine Gambardella, Mario Lusini, Massimo Chello, Christophe Acar
OBJECTIVE: The most efficient surgical approach to severe aortic valve disease in the young adult is still debated: cryopreserved aortic allograft offers excellent hemodynamic and avoid anticoagulation, but long-term durability is influenced by structural valve deterioration (SVD). This study aimed to describe long-term results of aortic allografts and to identify factors influencing long-term durability. METHODS: From January 1993 to August 2010, 210 patients underwent aortic allograft replacement via the free-hand subcoronary implantation technique (N = 55) or root replacement with coronary reimplantation (N = 155)...
April 18, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29749912/comparative-durability-and-costs-analysis-of-ventricular-shunts
#8
Nitin Agarwal, Ahmed Kashkoush, Michael M McDowell, William R Lariviere, Naveed Ismail, Robert M Friedlander
OBJECTIVE Ventricular shunt (VS) durability has been well studied in the pediatric population and in patients with normal pressure hydrocephalus; however, further evaluation in a more heterogeneous adult population is needed. This study aims to evaluate the effect of diagnosis and valve type-fixed versus programmable-on shunt durability and cost for placement of shunts in adult patients. METHODS The authors retrospectively reviewed the medical records of all patients who underwent implantation of a VS for hydrocephalus at their institution over a 3-year period between August 2013 and October 2016 with a minimum postoperative follow-up of 6 months...
May 11, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29749108/biomaterial-characterization-of-off-the-shelf-decellularized-porcine-pericardial-tissue-for-use-in-prosthetic-valvular-applications
#9
Joshua A Choe, Soumen Jana, Brandon J Tefft, Ryan S Hennessy, Jason Go, David Morse, Amir Lerman, Melissa D Young
Fixed pericardial tissue is commonly used for commercially available xenograft valve implants, and has proven durability, but lacks the capability to remodel and grow. Decellularized porcine pericardial tissue has the promise to outperform fixed tissue and remodel, but the decellularization process has been shown to damage the collagen structure and reduce mechanical integrity of the tissue. Therefore, a comparison of uniaxial tensile properties was performed on decellularized, decellularized-sterilized, fixed, and native porcine pericardial tissue, versus native valve leaflet cusps...
May 10, 2018: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/29743415/management-of-incomplete-initial-repair-in-the-treatment-of-degenerative-mitral-insufficiency
#10
Wenrui Ma, Wei Shi, Wei Zhang, Weihua Wu, Wei Ye, Ye Kong
We sought to present our institutional protocol to manage incomplete initial repair of degenerative mitral regurgitation and to evaluate its mid-term outcomes. Eight hundred and fifteen patients with degenerative mitral insufficiency undergoing mitral valve repair were investigated in this study. The initial repair attempt was incomplete in 48 patients, leaving a degree of residual regurgitation > mild, and an elevated transmitral gradient or systolic anterior motion (SAM). These patients were further treated with medication or mitral valve re-repair or replacement under reinstituted cardiopulmonary bypass...
May 9, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29741488/long-term-durability-and-hemodynamic-performance-of-a-self-expanding-transcatheter-heart-valve-beyond-5-years-after-implantation-a-prospective-observational-study-applying-the-standardized-definitions-of-structural-deterioration-and-valve-failure
#11
Erik W Holy, Julia Kebernik, Mohammad Abdelghani, Simon F Stämpfli, Jens Hellermann, Abdelhakim Allali, Mohamed El-Mawardy, Susanne Sachse, Thomas F Lüscher, Felix C Tanner, Gert Richardt, Mohamed Abdel-Wahab
AIMS: Long-term results of transcatheter aortic valve implantation (TAVI), in particular the incidence of bioprosthetic valve failure (BVF), are uncertain. METHODS AND RESULTS: The study prospectively included all 152 patients who had undergone TAVI with the self-expanding CoreValve™ up to December 2011 at the Heart Center, Bad Segeberg, Germany. Late BVF (>30 days) was defined as either: 1) Severe structural valve deterioration (trans-prosthetic mean pressure gradient ≥40 mmHg and/or ≥20 mmHg rise from baseline OR severe intra-prosthetic aortic regurgitation), OR 2) Bioprosthetic valve dysfunction leading to death or re-intervention...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29741485/one-year-results-of-transcatheter-treatment-of-severe-tricuspid-regurgitation-using-the-edge-to-edge-repair-technique
#12
Daniel Braun, Michael Nabauer, Mathias Orban, Andrea Englmaier, Diana Rösler, Christian Hagl, Steffen Massberg, Jörg Hausleiter
AIMS: The aim of this study was to evaluate one-year durability and clinical outcome of transcatheter tricuspid valve repair using the edge-to-edge repair technique in symptomatic patients with severe tricuspid regurgitation (TR). METHODS AND RESULTS: We evaluated twenty-four consecutive patients suffering from severe right sided heart failure (NYHA III-IV) primarily due to moderate to severe primary tricuspid regurgitation. Applying a modified steering technique for clip delivery, 8 patients were treated for isolated severe TR, while 16 patients were treated for moderate to severe TR and concomitant severe mitral regurgitation...
May 8, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29735584/bioprosthetic-aortic-valve-durability-in-the-era-of-transcatheter-aortic-valve-implantation
#13
REVIEW
Erwan Salaun, Marie-Annick Clavel, Josep Rodés-Cabau, Philippe Pibarot
The main limitation of bioprosthetic valves is their limited durability, which exposes the patient to the risk of aortic valve reintervention. Transcatheter aortic valve implantation (TAVI) is considered a reasonable alternative to surgical aortic valve replacement (SAVR) in patients with intermediate or high surgical risk. TAVI is now rapidly expanding towards the lower risk populations. Although the results of midterm durability of the transcatheter bioprostheses are encouraging, their long-term durability remains largely unknown...
May 7, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29729267/good-five-year-durability-of-transapical-beating-heart-off-pump-mitral-valve-repair-with-neochordae
#14
Philipp Kiefer, Sabine Meier, Thilo Noack, Michael Andrew Borger, Joerg Ender, Alexandro Hoyer, Friedrich Wilhelm Mohr, Joerg Seeburger
BACKGROUND: Transapical, beating heart, off-pump implantation of neochordae for repair of mitral valve (MV) prolapse is of increasing interest. The aim of this study was to evaluate long term results for MV repair using the NeoChord system. METHODS: Six patients underwent treatment for severe primary mitral regurgitation (MR) using the NeoChord DS1000 system as part of the initial device safety and feasibility Transapical Artificial Chordae Tendinae (TACT) trial at our institution...
May 2, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29729266/good-five-year-durability-of-transapical-beating-heart-off-pump-mitral-valve-repair-with-neochordae-commentary
#15
Gino Gerosa
No abstract text is available yet for this article.
May 2, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29724597/robotic-mitral-valve-operations-by-experienced-surgeons-are-cost-neutral-and-durable-at-1-year
#16
Garrett Coyan, Lawrence M Wei, Andrew Althouse, Harold G Roberts, Drew Schauble, Takashi Murashita, Chris C Cook, J Scott Rankin, Vinay Badhwar
BACKGROUND: Robotic mitral valve surgery has potential advantages in patient satisfaction and 30-day outcome. Cost concerns and repair durability limit wider adoption of robotic technology. This study examined detailed cost differences between robotic and sternotomy techniques in relation to outcomes and durability following robotic mitral program initiation. METHODS: Between April 2013 and October 2015, 30-day and 1-year outcomes of 328 consecutive patients undergoing robotic or sternotomy mitral valve repair or replacement by experienced surgeons were examined...
April 12, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29715592/fucoidan-vegf-based-surface-modification-of-decellularized-pulmonary-heart-valve-improves-the-antithrombotic-and-re-endothelialization-potential-of-bioprostheses
#17
N Marinval, M Morenc, M N Labour, A Samotus, A Mzyk, V Ollivier, M Maire, K Jesse, K Bassand, A Niemiec-Cyganek, O Haddad, M P Jacob, F Chaubet, N Charnaux, P Wilczek, H Hlawaty
Decellularized porcine heart valves offer promising potential as biocompatible prostheses. However, this procedure alter matrix fibres and glycans, leading to lower biomechanical resistance and increased their thrombotic potential. Therefore, their durability is limited due to calcification and weak regeneration in vivo. Surface modifications are highly requested to improve the scaffolds re-endothelialization required to restore functional and haemocompatible heart valve. Fucoidan, a natural sulphated polysaccharide, carries antithrombotic and anti-inflammatory properties and is known to enhance endothelial adhesion and proliferation when associated with vascular endothelial growth factor (VEGF)...
March 16, 2018: Biomaterials
https://www.readbyqxmd.com/read/29709354/simple-versus-complex-degenerative-mitral-valve-disease
#18
Hoda Javadikasgari, Tomislav Mihaljevic, Rakesh M Suri, Lars G Svensson, Jose L Navia, Robert Z Wang, Bassman Tappuni, Ashley M Lowry, Kenneth R McCurry, Eugene H Blackstone, Milind Y Desai, Stephanie L Mick, A Marc Gillinov
OBJECTIVES: At a center where surgeons favor mitral valve (MV) repair for all subsets of leaflet prolapse, we compared results of patients undergoing repair for simple versus complex degenerative MV disease. METHODS: From January 1985 to January 2016, 6153 patients underwent primary isolated MV repair for degenerative disease, 3101 patients underwent primary isolated MV repair for simple disease (posterior prolapse), and 3052 patients underwent primary isolated MV repair for complex disease (anterior or bileaflet prolapse), based on preoperative echocardiographic images...
April 4, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29701388/trifecta-bioprothesis-for-aortic-valve-replacement-our-experience
#19
João Pedro Monteiro, Diogo Rijo, Sara Simões Costa, Rodolfo Pereira, Ricardo Ferraz, Miguel Guerra
INTRODUCTION: Bioprosthesis are increasingly used for aortic valve replacement (AVR), as a result of increasing elderly patients, as well as, continuous improvements in durability and hemodynamic performance of pericardial prosthesis. The Trifecta aortic prosthesis is a latest-generation trileaflet stented pericardial valve designed for supra-annular placement in the aortic position. This study establishes the safety and early clinical and hemodynamic performance of the Trifecta valve...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29691047/valve-sparing-repair-of-sinus-of-valsalva-aneurysm-does-early-success-predict-long-term-durability
#20
EDITORIAL
Benjamin C Degner, Leonard N Girardi
No abstract text is available yet for this article.
April 4, 2018: Journal of Thoracic and Cardiovascular Surgery
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