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Stanford type A

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https://www.readbyqxmd.com/read/29770454/streamlining-a-blood-center-and-hospital-transfusion-service-supply-chain-with-an-informatics-vendor-managed-inventory-solution-development-implementation-and-3-month-follow-up
#1
Hamilton C Tsang, Adam Garcia, Robert Scott, David Lancaster, Dianne Geary, Anh-Thu Nguyen, Raina Shankar, Leslie Buchanan, Tho D Pham
BACKGROUND: The ordering process at Stanford Health Care involved twice-daily shipments predicated upon current stock levels from the blood center to the hospital transfusion service. Manual census determination is time consuming and error prone. We aimed to enhance inventory management by developing an informatics platform to streamline the ordering process and reallocate staff productivity. STUDY DESIGN AND METHODS: The general inventory accounts for more than 50 product categories based on characteristics including component, blood type, irradiation status, and cytomegalovirus serology status...
May 16, 2018: Transfusion
https://www.readbyqxmd.com/read/29734380/mitochondrial-modulation-induced-activation-of-vagal-sensory-neuronal-subsets-by-antimycin-a-but-not-cccp-or-rotenone-correlates-with-mitochondrial-superoxide-production
#2
Katherine R Stanford, Thomas E Taylor-Clark
Inflammation causes nociceptive sensory neuron activation, evoking debilitating symptoms and reflexes. Inflammatory signaling pathways are capable of modulating mitochondrial function, resulting in reactive oxygen species (ROS) production, mitochondrial depolarization and calcium release. Previously we showed that mitochondrial modulation with antimycin A, a complex III inhibitor, selectively stimulated nociceptive bronchopulmonary C-fibers via the activation of transient receptor potential (TRP) ankyrin 1 (A1) and vanilloid 1 (V1) cation channels...
2018: PloS One
https://www.readbyqxmd.com/read/29717401/modelling-mortality-and-discharge-of-hospitalized-stroke-patients-using-a-phase-type-recovery-model
#3
Bruce Jones, Sally McClean, David Stanford
We model the length of in-patient hospital stays due to stroke and the mode of discharge using a phase-type stroke recovery model. The model allows for three different types of stroke: haemorrhagic (the most severe, caused by ruptured blood vessels that cause brain bleeding), cerebral infarction (less severe, caused by blood clots) and transient ischemic attack or TIA (the least severe, a mini-stroke caused by a temporary blood clot). A four-phase recovery process is used, where the initial phase depends on the type of stroke, and transition from one phase to the next depends on the age of the patient...
May 1, 2018: Health Care Management Science
https://www.readbyqxmd.com/read/29708037/thoracic-endovascular-aortic-repair-to-treat-uncomplicated-stanford-type-b-aortic-dissection-the-surgeon-s-dilemma-to-preventing-future-complications
#4
Piergiorgio Tozzi
Uncomplicated type B aortic dissections have traditionally been managed non-operatively with aggressive blood pressure control. However, the best medical treatment is associated with a considerable risk of disease progression to complicated dissection or aneurysmal degeneration of the affected aortic segment. Thoracic endovascular aortic repair could prevent long-term complications but, because the dissected aorta is vulnerable, it is a high-risk procedure performed in asymptomatic patient. Therefore, endovascular treatment is not a solution for all patients and it should be performed only in the subgroup prone to developing progression of the disease and future complications...
June 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29707315/inflammation-is-related-to-preoperative-hypoxemia-in-patients-with-acute-stanford-type-a-aortic-dissection
#5
Xu-Zhou Duan, Zhi-Yun Xu, Fang-Lin Lu, Lin Han, Yang-Feng Tang, Hao Tang, Yang Liu
Background: Preoperative hypoxemia is a frequent complication of acute Stanford type A aortic dissection (ATAAD). The aim of the present study was to determine which factors were associated with hypoxemia. Methods: A series of data were collected in a statistical analysis to evaluate preoperative hypoxemia in patients with ATAAD. After retrospectively analyzing data for 172 patients, we identified the risk factors for preoperative hypoxemia. Hypoxemia was defined by an arterial partial pressure of oxygen to fraction of inspired oxygen (PaO2 /FiO2 ) ratio of 200 or lower...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29698013/disclosure-and-holding-back-communication-psychological-adjustment-and-marital-satisfaction-among-couples-coping-with-osteoarthritis
#6
Ruixue Zhaoyang, Lynn M Martire, Ashley M Stanford
This study examined two types of illness-related communication (disclosure and holding back) and their associations with psychological adjustment and marital satisfaction in patients with knee osteoarthritis (OA) and their spouses. A sample of 142 couples reported on disclosure and holding back of OA-related concerns, marital satisfaction, and depressive symptoms at two time points across 1 year. Results from dyadic analyses indicated that holding back was associated with decreases in one's own marital satisfaction for patients and spouses and increases in one's own depressive symptoms for spouses over 1 year...
April 2018: Journal of Family Psychology: JFP
https://www.readbyqxmd.com/read/29684558/effects-of-exercise-on-brown-and-beige-adipocytes
#7
REVIEW
Revati S Dewal, Kristin I Stanford
Physical exercise leads to beneficial effects in numerous tissues and organ systems and offers protection against obesity and type 2 diabetes. Recent studies have investigated the role of exercise on brown adipose tissue (BAT) and white adipose tissue (WAT), and have indicated marked adaptations to each tissue with exercise. Studies investigating the effects of exercise on BAT have produced conflicting results, with some showing an increase in the thermogenic activity of BAT and some demonstrating a decrease in the thermogenic activity of BAT...
April 20, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29675443/left-ventricular-intussusception-of-an-intimal-flap-in-an-aortic-dissection-stanford-type-a
#8
Tim Kaufeld, Malakh Shrestha, Axel Haverich, Andreas Martens
A 75-year-old woman was admitted to the emergency department with severe and sudden chest pain. Transthoracic echocardiogram showed an unusual case of aortic dissection Stanford Type A with complete circumferential detachment of the ascending aorta intima. An intussusception of the intima flap into the left ventricular outflow tract was also observed. This case presents a very rare surgical treatment involving root repair using tissue adhesives for a left ventricular intimal flap.
June 2017: Aorta (Stamford, Conn.)
https://www.readbyqxmd.com/read/29662703/aortic-dissection-presenting-as-acute-pancreatitis-suspecting-the-unexpected
#9
Adam Hafeez, Dillon Karmo, Adrian Mercado-Alamo, Alexandra Halalau
Aortic dissection is a life-threatening condition in which the inner layer of the aorta tears. Blood surges through the tear, causing the inner and middle layers of the aorta to separate (dissect). It is considered a medical emergency. We report a case of a healthy 56-year-old male who presented to the emergency room with sudden onset of epigastric pain radiating to his back. His blood pressure was 167/91 mmHg, equal in both arms. His lipase was elevated at 1258 U/L, and he was clinically diagnosed with acute pancreatitis (AP)...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29649018/frequency-of-map2k1-tp53-and-u2af1-mutations-in-braf-mutated-langerhans-cell-histiocytosis-further-characterizing-the-genomic-landscape-of-lch
#10
Lisa M McGinnis, Grant Nybakken, Lisa Ma, Daniel A Arber
Langerhans cell histiocytosis is a proliferative disorder of neoplastic Langerhans cells with activating mutations in the Erk signaling pathway. TP53 and U2AF1 mutations have been implicated in other myelomonocytic malignancies and we hypothesized that mutations in these genes may cosegregate in LCH patients according to BRAF mutation status. Towards this end, we collected cases with a pathologic diagnosis of Langerhans cell histiocytosis from Stanford University Hospital. We analyzed the status of known pathogenic alleles in BRAF, ARAF, TP53, U2AF1, and MAP2K1 on formalin-fixed, paraffin-embedded tissue by direct sequencing...
April 11, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29629837/impact-of-hypertension-on-early-outcomes-and-long-term-survival-of-patients-undergoing-aortic-repair-with-stanford-a-dissection
#11
Julia Merkle, Anton Sabashnikov, Antje-Christin Deppe, Mohamed Zeriouh, Kaveh Eghbalzadeh, Carolyn Weber, Parwis Rahmanian, Elmar Kuhn, Navid Madershahian, Axel Kroener, Yeong-Hoon Choi, Ferdinand Kuhn-Régnier, Oliver Liakopoulos, Thorsten Wahlers
INTRODUCTION: Stanford A acute aortic dissection (AAD) is a life-threatening emergency, typically occurring in hypertensive patients, requiring immediate surgical repair. The aim of this study was to evaluate early outcomes and long-term survival of hypertensive patients in comparison to normotensive patients suffering from Stanford A AAD. METHODS: In our center, 240 patients with Stanford A AAD underwent aortic surgical repair from January 2006 to April 2015. After statistical and logistic regression analysis, Kaplan-Meier survival estimation was performed, with up to 9-year follow-up...
April 1, 2018: Perfusion
https://www.readbyqxmd.com/read/29629067/a-prospective-study-of-psychomotor-performance-of-driving-among-two-kinds-of-shift-work-in-iran
#12
Soheil Saadat, Mojgan Karbakhsh, Mahnaz Saremi, Iraj Alimohammadi, Hassan Ashayeri, Mahsa Fayaz, Farideh Sadeghian, Reza Rostami
Background and aim: Driving after a night shift imposes a risk on health care professionals and other road users. The aim of this study was to measure psychomotor performance of driving of night shift nurses compared to day-shift nurses. Methods: Forty-seven volunteer female nurses working at Sina hospital in Tehran, Iran, with a call in all departments of hospital, participated in this study (23 night shift and 24 day shift nurses) in 2016. The tests included RT for simple reaction time, ATAVT for perceptual speed, LVT for visual orientation and ZBA for time anticipation...
February 2018: Electronic Physician
https://www.readbyqxmd.com/read/29627025/cerebrovascular-imaging-of-cerebral-ischemia-in-acute-type-a-aortic-dissection
#13
Soichiro Matsubara, Masatoshi Koga, Tomoyuki Ohara, Yasuyuki Iguchi, Kenji Minatoya, Yoshio Tahara, Tetsuya Fukuda, Yuichi Miyazaki, Katsufumi Kajimoto, Yuki Sakamoto, Naoki Makita, Naoki Tokuda, Kazuyuki Nagatsuka, Yukio Ando, Kazunori Toyoda
BACKGROUND AND PURPOSE: Stanford type A aortic dissection (AAD) sometimes causes acute ischemic stroke (AIS) or transient ischemic attack (TIA). There is little understanding of cerebrovascular imaging of AIS or TIA in patients with AAD. METHODS: Consecutive AIS/TIA patients with AAD who were admitted within 4.5 h of onset were reviewed. We compared findings of MRI/MRA between these and consecutive AIS/TIA patients without AAD within 4.5 h of onset. RESULTS: Seventeen AAD and 249 non-AAD patients were identified...
May 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29626287/suppressive-effect-of-pitavastatin-on-aortic-arch-dilatation-in-acute-stanford-type-b-aortic-dissection-analysis-of-stanp-trial
#14
Naoki Masaki, Kiichiro Kumagai, Konosuke Sasaki, Satoshi Matsuo, Naotaka Motoyoshi, Osamu Adachi, Masatoshi Akiyama, Shunsuke Kawamoto, Koichi Tabayashi, Yoshikatsu Saiki
OBJECTIVES: Medical therapy for patients with uncomplicated acute type B aortic dissection (ABAD) is essentially accepted for its excellent early outcome; however, long-term outcomes have not been satisfactory due to aorta-related complications. This trial was performed to investigate the efficacy of a statin as an additive that may enhance the effectiveness of conventional medical treatment in patients with ABAD. METHODS: This was a multi-center, prospective, and randomized comparative investigation of patients with uncomplicated ABAD...
April 6, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29617826/long-term-outcomes-of-total-arch-replacement-with-the-non-frozen-elephant-trunk-technique-for-stanford-type-a-acute-aortic-dissection
#15
Yosuke Inoue, Hitoshi Matsuda, Atsushi Omura, Yoshimasa Seike, Kyokun Uehara, Hiroaki Sasaki, Junjiro Kobayashi
OBJECTIVES: Arch repair using the frozen elephant trunk (FET) technique has been utilized to treat Type A acute aortic dissection. In contrast, the long-term outcomes of the non-FET technique focus on the thrombosed false lumen (FL), and distal aortic reoperation rates remain unclear. The goal of our study was to investigate the efficacy and long-term outcomes of the non-FET technique as the benchmark. METHODS: We reviewed 518 patients with Type A acute aortic dissection in the last 20 years...
March 29, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29615333/immediate-operation-for-acute-type-a-aortic-dissection-complicated-by-visceral-or-peripheral-malperfusion
#16
Peter Chiu, Sarah Tsou, Andrew B Goldstone, Mikaela Louie, Y Joseph Woo, Michael P Fischbein
OBJECTIVE: To evaluate the effect of visceral, renal, or peripheral malperfusion on the outcome of acute type A aortic dissection. METHODS: We performed a retrospective review of the acute type A aortic dissection experience at Stanford Hospital between January 2005 and December 2015. Inverse probability weighting was used to account for differences between patients who experienced malperfusion syndromes and those who did not. Weighted logistic regression was used to evaluate in-hospital mortality, and midterm survival was assessed with the restricted mean survival time and weighted Cox regression...
February 21, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29608664/what-is-the-optimal-surgical-strategy-for-stanford-type-a-acute-aortic-dissection-in-patients-with-a-patent-false-lumen-at-the-descending-aorta
#17
Yosuke Inoue, Hitoshi Matsuda, Atsushi Omura, Yoshimasa Seike, Kyokun Uehara, Hiroaki Sasaki, Junjiro Kobayashi
OBJECTIVES: Aggressive total arch replacement (TAR) to obtain thrombosis of the distal false lumen (FL) in patients with Stanford Type A acute aortic dissection, particularly with a patent FL at the descending aorta, is discussed. The aim of this study was to examine the efficacy of our strategy. METHODS: In the last 20 years, we retrospectively reviewed the records of 518 patients with Type A acute aortic dissection who underwent an emergent surgery. Among them, 290 patients with a preoperative patent FL at the descending aorta were enrolled in this study...
March 28, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29600127/the-diagnostic-accuracy-of-the-mediastinal-width-on-supine-anteroposterior-chest-radiographs-with-nontraumatic-stanford-type-a-acute-aortic-dissection
#18
Hiraku Funakoshi, Michiko Mizobe, Yosuke Homma, Yoshiyuki Nakashima, Jin Takahashi, Takashi Shiga
Background: Nontraumatic Stanford type A acute aortic dissection is a life-threatening condition; thus, the ability to make a precise diagnosis of nontraumatic Stanford type A acute aortic dissection is essential for the emergency physician. Several reports have shown that the mediastinal widening on a chest radiograph is useful for the diagnosis of nontraumatic Stanford type A acute aortic dissection; however, the exact cutoff value of the mediastinal width on plain radiographs is rarely defined...
March 2018: Journal of General and Family Medicine
https://www.readbyqxmd.com/read/29582625/lower-limb-ischemia-management-in-acute-stanford-type-a-aortic-dissection
#19
Marco Gennari, Francesco G Arlati, Gianluca Polvani, Andrea Annoni, Marco Morpurgo, Marco Agrifoglio
No abstract text is available yet for this article.
April 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29580243/factors-associated-with-the-use-of-cognitive-aids-in-operating-room-crises-a-cross-sectional-study-of-us-hospitals-and-ambulatory-surgical-centers
#20
Shehnaz Alidina, Sara N Goldhaber-Fiebert, Alexander A Hannenberg, David L Hepner, Sara J Singer, Bridget A Neville, James R Sachetta, Stuart R Lipsitz, William R Berry
BACKGROUND: Operating room (OR) crises are high-acuity events requiring rapid, coordinated management. Medical judgment and decision-making can be compromised in stressful situations, and clinicians may not experience a crisis for many years. A cognitive aid (e.g., checklist) for the most common types of crises in the OR may improve management during unexpected and rare events. While implementation strategies for innovations such as cognitive aids for routine use are becoming better understood, cognitive aids that are rarely used are not yet well understood...
March 26, 2018: Implementation Science: IS
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