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RANDOMIZED CONTROLLED TRIAL
M Attal, D Blaise, G Marit, C Payen, M Michallet, J P Vernant, C Sauvage, X Troussard, G Nedellec, J Pico
A prospective, randomized trial was initiated in adult acute lymphoblastic leukemia (ALL) to compare (1) disease-free survival (DFS) after allogeneic or autologous bone marrow transplantation (BMT) and (2) the relapse rate of patients treated with or without interleukin-2 (IL-2) after autologous BMT. A total of 135 previously untreated patients, aged under 55 years, received the Berlin-Frankfurt-Muster (BFM) induction regimen: 126 patients (93%), of which 120 were HLA-typed, achieved complete remission (CR)...
August 15, 1995: Blood
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