Mark Lundeen, Jason L Hurd, Matthew Hayes, Meredith Hayes, Tiffany R Facile, John P Furia, Nicola Maffulli, Christopher Alt, Eckhard U Alt, Christoph Schmitz, David A Pearce
Symptomatic, partial-thickness rotator cuff tears (sPTRCT) are problematic. This study tested the hypothesis that management of sPTRCT with injection of fresh, uncultured, unmodified, autologous, adipose-derived regenerative cells (UA-ADRCs) is safe and more effective than injection of corticosteroid even in the long run. To this end, subjects who had completed a former randomized controlled trial were enrolled in the present study. At baseline these subjects had not responded to physical therapy treatments for at least 6 weeks, and were randomly assigned to receive respectively a single injection of UA-ADRCs (n = 11) or a single injection of methylprednisolone (n = 5)...
November 7, 2023: Scientific Reports