keyword
https://read.qxmd.com/read/38306409/morbidity-and-mortality-in-adults-with-a-fontan-circulation-beyond-the-fourth-decade-of-life
#21
JOURNAL ARTICLE
Andrew Constantine, Paolo Ferrero, Elena Gribaudo, Panagiota Mitropoulou, Kaushiga Krishnathasan, Giulia Costola, Myo T Lwin, Samantha Fitzsimmons, Margarita Brida, Claudia Montanaro, Aleksander Kempny, Ee Ling Heng, Massimo Chessa, Konstantinos Dimopoulos, Isma Rafiq
AIMS: To evaluate the late outcomes of adults (above 35 years) with a Fontan-type circulation, for whom current data on morbidity and mortality are lacking. METHODS AND RESULTS: Data were collected retrospectively on consecutive patients with Fontan circulation above the age of 35 years followed in three European specialist centres. Overall, 115 Fontan patients were included [median age 35 (range 35-48) years, 47.8% female]. The most common underlying congenital heart disease diagnosis was tricuspid atresia (n = 58, 50...
February 2, 2024: European Journal of Preventive Cardiology
https://read.qxmd.com/read/38305807/cardiovascular-magnetic-resonance-in-muscular-dystrophies-looking-ahead
#22
JOURNAL ARTICLE
Ana Filipa Amador, Teresa Pinho, Catarina Martins da Costa, António José Madureira, Elisabete Martins
Cardiac magnetic resonance (CMR) is an established tool for risk stratification in several cardiomyopathies, and its role in muscular dystrophies (MuD) looks promising. We sought to assess how CMR performs in predicting cardiac events in a real cohort of MuD patients. A prospective single-center study with the enrollment of consecutive adult MuD patients referred to cardiac screening from 2012 to 2018 with the collection of clinical and CMR data. During follow-up (FUP), major adverse cardiac events were considered a composite of device implantation, ventricular tachycardia (VT), hospitalization due to heart failure, and death...
February 2, 2024: Monaldi Archives for Chest Disease
https://read.qxmd.com/read/38295197/focused-cardiac-ultrasound-diagnosis-of-dilated-cardiomyopathy
#23
JOURNAL ARTICLE
Ag Nuwan D Perera, Kathleen A Noorbakhsh, Jennifer R Marin, Devora B Azhdam
We report the case of a 6-year-old boy presenting to the emergency department after a syncopal event during a flu-like illness. Intermittent ventricular tachycardia was noted during Emergency Medical Services transport, and a focused cardiac ultrasound (FOCUS) in the emergency department revealed a dilated left ventricle and left atrium as well as severe global systolic dysfunction. Point-of-care ultrasound findings prompted expedited evaluation and management of this critically ill patient.
February 1, 2024: Pediatric Emergency Care
https://read.qxmd.com/read/38288204/apical-hypertrophic-cardiomyopathy-a-fatal-yet-underappreciated-variant-of-hypertrophic-cardiomyopathy
#24
Sherif Eltawansy, Lauren Klei, Steven Imburgio, Megan Decker, Ndausung Udongwo, Anas Alrefaee, Anton Mararenko, Nelson Lamarche
Hypertrophic cardiomyopathy (HCM) is a group of diseases affecting the left ventricle heart muscle that share a common feature of left ventricular hypertrophy without associated cardiac or systemic disorder. It was found to have a genetic basis with autosomal dominant mutations in the sarcomeric protein genes. Apical HCM is a rare subtype and underappreciated variant of HCM that primarily affects the apex of the heart. Apical HCM is dissimilar to classic HCM, with more challenges in diagnosis and inconsistent clinical course than other types...
December 2023: Curēus
https://read.qxmd.com/read/38282168/prognostic-relevance-of-ischemic-late-gadolinium-enhancement-in-apparently-healthy-endurance-athletes-a-follow-up-study-over-5%C3%A2-years
#25
JOURNAL ARTICLE
Gunnar K Lund, Sharon Leptin, Haissam Ragab, Martin R Sinn, Alexander Fierenz, Ersin Cavus, Kai Muellerleile, Hang Chen, Jennifer Erley, Phillip Harms, Anna Kisters, Jitka Starekova, Gerhard Adam, Enver Tahir
BACKGROUND: In many cardiac diseases, myocardial scar tissue detected by late gadolinium enhancement (LGE) is a risk factor for cardiac arrhythmia and sudden cardiac death. Previous studies in athletes reported an increased risk for cardiac events in this group of ostensibly healthy subjects. However, the currently available longitudinal studies on this topic included fairly old marathon runners with a mean age of 57 ± 6 years or represent a case-control study in athletes with preexisting ventricular arrhythmia...
January 29, 2024: Sports Medicine—Open
https://read.qxmd.com/read/38279754/arrhythmias-and-hypertrophic-cardiomyopathy-unravelling-the-connection
#26
JOURNAL ARTICLE
Kanishk Aggarwal, Sri Pranvi Boyapati, Jayesh Valecha, Amna Noor, Fnu Kanwal, Rohit Jain, Sai Gautham Kanagala
Hypertrophic cardiomyopathy (HCM) results from gene mutations affecting cardiac sarcomeres and is inherited in an autosomal dominant manner. With a prevalence of 1:200-1:500 in the general population, HCM is characterised by a hypertrophied and non-dilated left ventricle with predominant involvement of the interventricular septum. The myocardium's structural and intracellular factors, combined with triggers such as physical exertion, autonomic dysfunction, and ischemia, can lead to reentry events, and atrial and ventricular arrhythmias, including atrial fibrillation (AF) which is common among HCM patients...
January 24, 2024: Current Cardiology Reviews
https://read.qxmd.com/read/38279155/treatment-strategy-for-heart-failure-complicated-with-complete-left-bundle-branch-block-and-atrial-tachycardia-a-case-report
#27
JOURNAL ARTICLE
Jian Wang, Qing-Qing Zhang, Jie Lin, Wei Yuan, Li-Chun Wang, Yu-Cheng Wu
BACKGROUND: For patients with heart failure combined with complete left bundle branch block, cardiac resynchronization therapy is an important therapeutic method. If these patients also have atrial tachycardia, how to choose a treatment strategy deserves discussion. CASE PRESENTATION: A Chinese woman in her early 70s was admitted due to recurrent episodes of chest distress and asthma for 1 year. Physical and laboratory examinations showed filling of the jugular vein, lung rales, left enlargement of the heart boundary, edema of the lower limbs and elevation of N-terminal pro b-type natriuretic peptide...
January 27, 2024: Journal of Medical Case Reports
https://read.qxmd.com/read/38264116/biventricular-activation-of-right-bundle-branch-block-pattern-ventricular-tachycardia-originating-from-the-right-ventricle-in-ebstein-s-anomaly
#28
JOURNAL ARTICLE
Kazuo Sakamoto, Susumu Takase, Yuki Ikeda, Ichiro Sakamoto
No abstract text is available yet for this article.
January 2024: HeartRhythm Case Reports
https://read.qxmd.com/read/38251047/opportunities-and-challenges-in-catheter-based-irreversible-electroporation-for-ventricular-tachycardia
#29
REVIEW
Matthew Leonard Repp, Ikeotunye Royal Chinyere
The use of catheter-based irreversible electroporation in clinical cardiac laboratories, termed pulsed-field ablation (PFA), is gaining international momentum among cardiac electrophysiology proceduralists for the non-thermal management of both atrial and ventricular tachyrhythmogenic substrates. One area of potential application for PFA is in the mitigation of ventricular tachycardia (VT) risk in the setting of ischemia-mediated myocardial fibrosis, as evidenced by recently published clinical case reports...
January 10, 2024: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://read.qxmd.com/read/38243315/trans-apical-catheter-ablation-of-ventricular-tachycardia-in-a-patient-with-metallic-aortic-and-mitral-valves
#30
JOURNAL ARTICLE
Ali Bozorgi, Saeed Sadeghian, Entezar Mehrabi Nasab
We present a patient with a history of heart failure and metallic aortic and mitral valves surgeries, who required ablation for a drug-refractory left ventricular tachycardia. But the metallic valves prohibited the insertion of catheters via retrograde or via trans-septal approaches. Therefore, we decided to perform catheter ablation by direct left ventricle puncture through a minithoracotomy. The arrhythmia was successfully ablated via of trans-apical approach and did not recur at six months follow-up.
January 20, 2024: Journal of Cardiothoracic Surgery
https://read.qxmd.com/read/38225554/shorter-antitubercular-therapy-for-extrapulmonary-tuberculosis-a-case-report
#31
JOURNAL ARTICLE
Diviya Bharathi Ravikumar, Barath Prashanth Sivasubramanian, Ankur Singla, Rakshaya Venu, Saketh Palasamudram Shekar
INTRODUCTION: Extrapulmonary tuberculosis (EPTB) adds to India's significant economic burden, with pericardial effusion being a potentially fatal complication. This case report highlights the need for early diagnosis and the feasibility of shorter-duration treatment for EPTB in developing countries. PRESENTATION: This case report describes a 19-year-old male from Southeast Asia who had a history of bronchiectasis involving the left lower lobe and the right middle lobe, which was cystic in nature, as well as multiple episodes of non-tuberculous pneumonia...
January 15, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38224852/dual-effect-of-cardiac-fkbp12-6-overexpression-on-excitation-contraction-coupling-and-the-incidence-of-ventricular-arrhythmia-depending-on-its-expression-level
#32
JOURNAL ARTICLE
Marine Gandon-Renard, Almudena Val-Blasco, Célia Oughlis, Pascale Gerbaud, Florence Lefebvre, Susana Gomez, Clément Journé, Delphine Courilleau, Françoise Mercier-Nomé, Laetitia Pereira, Jean-Pierre Benitah, Ana Maria Gómez, Jean-Jacques Mercadier
FKBP12.6, a binding protein to the immunosuppressant FK506, which also binds the ryanodine receptor (RyR2) in the heart, has been proposed to regulate RyR2 function and to have antiarrhythmic properties. However, the level of FKBP12.6 expression in normal hearts remains elusive and some controversies still persist regarding its effects, both in basal conditions and during β-adrenergic stimulation. We quantified FKBP12.6 in the left ventricles (LV) of WT (wild-type) mice and in two novel transgenic models expressing distinct levels of FKBP12...
January 13, 2024: Journal of Molecular and Cellular Cardiology
https://read.qxmd.com/read/38206263/catheter-ablation-for-ventricular-tachycardia-in-patients-with-desmoplakin-cardiomyopathy
#33
JOURNAL ARTICLE
Alessio Gasperetti, Giovanni Peretto, Steven A Muller, Kanae Hasegawa, Paolo Compagnucci, Michela Casella, Brittney Murray, Crystal Tichnell, Richard T Carrick, Julia Cadrin-Tourigny, Marco Schiavone, Cynthia James, Ahmad S Amin, Ardan M Saguner, Antonio Dello Russo, Claudio Tondo, William Stevenson, Paolo Della Bella, Hugh Calkins, Harikrishna Tandri
BACKGROUND: Desmoplakin (DSP) pathogenic/likely pathogenic (P/LP) variants are associated with malignant phenotypes of arrhythmogenic cardiomyopathy (DSP-ACM). Reports of outcomes after ventricular tachycardia (VT) ablation in DSP-ACM are scarce. OBJECTIVES: In this study, the authors sought to report on long-term outcomes of VT ablation in DSP-ACM. METHODS: Patients with P/LP DSP variants at 9 institutions undergoing VT ablation were included...
December 14, 2023: JACC. Clinical Electrophysiology
https://read.qxmd.com/read/38206261/ventricular-tachycardia-ablation%C3%A2-in%C3%A2-patients-with-desmoplakin%C3%A2-cardiomyopathy
#34
JOURNAL ARTICLE
Michael Ghannam, Jackson J Liang, Jarieke Hoogendoorn, Katja Zeppenfeld, Konstantinos C Siontis, Samuel J Asirvatham, Frederic Sacher, Philippe Maury, Estelle Gandjbakhch, Fred Morady, Frank Bogun
BACKGROUND: Desmoplakin (DSP) pathogenic variants are rare causes of arrhythmogenic cardiomyopathy and often involve the right and left ventricles. Ventricular tachycardia (VT) ablations may be required in these patients, but procedural characteristics have not been reported. OBJECTIVES: In this study, the authors sought to report a multicenter experience of VT ablation in patients with DSP pathogenic variants. METHODS: VT ablations performed in patients with known DSP pathogenic variants were analyzed across 6 centers in 3 countries...
December 14, 2023: JACC. Clinical Electrophysiology
https://read.qxmd.com/read/38204539/ventricular-tachycardia-due-to-arrhythmogenic-right-ventricular-cardiomyopathy-in-the-setting-of-acute%C3%A2-coronary-syndrome
#35
Priyadarshini Dixit, Alex Adams, Gabriel Velez Oquendo, Joon Ahn
A 55-year-old man presented with sustained monomorphic ventricular tachycardia with a left bundle QRS complex pattern in the setting of non-ST-segment elevation myocardial infarction. The electrocardiographic morphology of the ventricular tachycardia and echocardiographic findings of significant right ventricular dysfunction led to the diagnosis of arrhythmogenic right ventricular cardiomyopathy.
December 20, 2023: JACC. Case reports
https://read.qxmd.com/read/38193796/performance-and-safety-of-temperature-and-flow-controlled-radiofrequency-ablation-for-ventricular-arrhythmia
#36
JOURNAL ARTICLE
Richard Kobza, Gabriela Hilfiker, Sophie Rissotto, Saagar Mahida, Christian Grebmer, Firat Duru, Helmut Pürerfellner, Benjamin Berte
AIMS: High-power ablation is effective for ventricular arrhythmia ablation; however, it increases the risk of steam pops. The aim of this study was to define the safety and efficacy of QMODE ablation in the ventricle and the risk of steam pop. METHODS AND RESULTS: Consecutive patients undergoing ventricular ablation using QDOT were included in a prospective single-centre registry. Procedural data, complications, and follow-up were systematically analysed and compared with a historical ventricular tachycardia (VT) and premature ventricular complexes (PVC) cohort ablated using STSF...
December 28, 2023: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://read.qxmd.com/read/38164773/fingers-on-the-wrist-and-taming-the-funny-current-rejuvenate-the-wounded-heart-ivabradine-responsive-atrial-tachycardia
#37
A Shaheer Ahmed, Gauravkumar Divani, Nitish Rai, Anwar Hussain Ansari
A 19-year-old male presented with dyspnea on exertion (New York Heart Association [NYHA] class II) and occasional palpitations for six months. He had initially been evaluated at another facility and diagnosed with dilated cardiomyopathy. Despite treatment, there was no improvement in his symptoms. On evaluation at our centre, his previous electrocardiograms appeared normal. However, palpation of his radial pulse for one minute revealed runs of regular tachycardia, interspersed with a normal pulse rate. A 30-second rhythm strip electrocardiogram (ECG) showed multiple runs of ectopic tachycardia originating from the right atrial appendage, interspersed with ectopic atrial rhythms...
December 2023: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://read.qxmd.com/read/38161843/cardiac-metastasis-presenting-as-right-ventricular-outflow-obstruction
#38
Isaac Alsallamin, Lama Quraiba, Sameer Mtour, Afnan Alsallamin
Right ventricular outflow tract obstruction (RVOTO) is characterized by an increased systolic pressure gradient between the right ventricle (RV) and the pulmonary artery. This rare condition can be diagnosed via echocardiography and may arise from various causes, including cardiac masses, pulmonary atresia with a ventricular septal defect, tricuspid valve thrombus, graft or wire calcification, or a cardiac tumor. We present the case of a 73-year-old male who was hospitalized after a syncope episode. Telemetry detected ventricular arrhythmia...
November 2023: Curēus
https://read.qxmd.com/read/38152949/effects-of-contact-force-on-lesion-size-during-pulsed-field-catheter-ablation-histochemical-characterization-of-ventricular-lesion-boundaries
#39
JOURNAL ARTICLE
Hiroshi Nakagawa, Quim Castellvi, Robert Neal, Steven Girouard, Jacob Laughner, Atsushi Ikeda, Masafumi Sugawara, Yoshimori An, Ayman A Hussein, Shady Nakhla, Tyler Taigen, Jakub Srounbek, Mohamed Kanj, Pasquale Santangeli, Walid I Saliba, Antoni Ivorra, Oussama M Wazni
BACKGROUND: Effects of contact force (CF) on lesion formation during pulsed field ablation (PFA) have not been well validated. The purpose of this study was to determine the relationship between average CF and lesion size during PFA using a swine-beating heart model. METHODS: A 7F catheter with a 3.5-mm ablation electrode and CF sensor (TactiCath SE, Abbott) was connected to a PFA system (CENTAURI, Galvanize Therapeutics). In 5 closed-chest swine, biphasic PFA current was delivered between the ablation electrode and a skin patch at 40 separate sites in right ventricle (28 Amp) and 55 separate sites in left ventricle (35 Amp) with 4 different levels of CF: (1) low (CF range of 4-13 g; median, 9...
December 28, 2023: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38095694/in-silico-optical-modulation-of-spiral-wave-trajectories-in-cardiac-tissue
#40
JOURNAL ARTICLE
Sayedeh Hussaini, Rupamanjari Majumder, Valentin Krinski, Stefan Luther
Life-threatening cardiac arrhythmias such as ventricular tachycardia and fibrillation are common precursors to sudden cardiac death. They are associated with the occurrence of abnormal electrical spiral waves in the heart that rotate at a high frequency. In severe cases, arrhythmias are combated with a clinical method called defibrillation, which involves administering a single global high-voltage shock to the heart to reset all its activity and restore sinus rhythm. Despite its high efficiency in controlling arrhythmias, defibrillation is associated with several negative side effects that render the method suboptimal...
December 2023: Pflügers Archiv: European Journal of Physiology
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