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https://www.readbyqxmd.com/read/28110517/cultural-safety-and-belonging-for-refugee-background-women-attending-group-pregnancy-care-an-australian-qualitative-study
#1
Elisha Riggs, Sumaiya Muyeen, Stephanie Brown, Wendy Dawson, Pauline Petschel, Waan Tardiff, Fiona Norman, Dannielle Vanpraag, Jo Szwarc, Jane Yelland
BACKGROUND: Refugee women experience higher incidence of childbirth complications and poor pregnancy outcomes. Resettled refugee women often face multiple barriers accessing pregnancy care and navigating health systems in high income countries. METHODS: A community-based model of group pregnancy care for Karen women from Burma was co-designed by health services in consultation with Karen families in Melbourne, Australia. Focus groups were conducted with women who had participated to explore their experiences of using the program, and whether it had helped them feel prepared for childbirth and going home with a new baby...
January 22, 2017: Birth
https://www.readbyqxmd.com/read/28110487/the-use-of-bilateral-internal-mammary-artery-grafting-in-different-degrees-of-obesity
#2
Yasser Y Hegazy, Wael Hassanein, Jürgen Ennker, Noha Keshk, Stefan Bauer, Ralf Sodian
Background Obesity is a limiting factor for the use of bilateral internal mammary arteries (BIMAs). Therefore, we assessed the safety of their use in different degrees of obesity. Patients and Methods We studied two groups of patients with obesity using propensity matching. The first group received single internal mammary artery and saphenous vein grafts (SIMA group, 526 patients) and the second group received bilateral internal mammary arteries (BIMA group, 526 patients). Patients were classified further according to their body mass index (BMI) into overweight (BMI = 25-29...
January 22, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/28110463/biomarkers-of-renal-tumors-the-current-state-and-clinical-perspectives
#3
REVIEW
Marina O Golovastova, Dmitry O Korolev, Larisa V Tsoy, Vladimir A Varshavsky, Wan-Hai Xu, Andrey Z Vinarov, Evgeni Yu Zernii, Pavel P Philippov, Andrey A Zamyatnin
Renal cell carcinoma (RCC) ranks the first death rate among the urogenital tumors, whereas its incidence follows the incidences of prostate and bladder cancer. The diagnosis of RCC at early stages allows immediately undertaking appropriate treatment, which significantly increases patients' survival rate. Early and accurate diagnosis avoids inadequate treatment, provides the disease progression forecast, and permits to apply more efficient therapy. Unfortunately, the small renal tumors are usually asymptomatic resulting in the late diagnosis and, therefore, low efficacy of treatment...
January 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28110453/update-on-the-diagnosis-and-treatment-of-cholangiocarcinoma
#4
REVIEW
Bryan Doherty, Vinod E Nambudiri, William C Palmer
PURPOSE OF REVIEW: Cholangiocarcinoma is a rare biliary adenocarcinoma associated with poor outcomes. Cholangiocarcinoma is subdivided into extrahepatic and intrahepatic variants. Intrahepatic cholangiocarcinoma is then further differentiated into (1) peripheral mass-forming tumors and (2) central periductal infiltrating tumors. We aimed to review the currently known risk factors, diagnostic tools, and treatment options, as well as highlight the need for further clinical trials and research to improve overall survival rates...
January 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28110415/antimicrobial-combination-treatment-including-ciprofloxacin-decreased-the-mortality-rate-of-pseudomonas-aeruginosa-bacteraemia-a-retrospective-cohort-study
#5
M Paulsson, A Granrot, J Ahl, J Tham, F Resman, K Riesbeck, F Månsson
Ineffective antimicrobial therapy of Pseudomonas aeruginosa bacteraemia increases mortality. Recent studies have proposed the use of antimicrobial combination therapy composed of a beta-lactam with either ciprofloxacin or tobramycin. To determine if combination therapy correlates to lower mortality and is superior compared to monotherapy, we investigated the effect of antimicrobial treatment regimens on 30-day mortality in a cohort with Pseudomonas aeruginosa bacteraemia. All cases of P. aeruginosa bacteraemia (n = 292) in southwest Skåne County, Sweden (years 2005-2010, adult population 361,112) and the whole county (2011-2012, 966,130) were identified...
January 21, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28110361/the-impact-of-routine-whole-spine-mri-screening-in-the-evaluation-of-spinal-degenerative-diseases
#6
Rishi Mugesh Kanna, Younis Kamal, Anupama Mahesh, Prakash Venugopal, Ajoy Prasad Shetty, S Rajasekaran
PURPOSE: Magnetic resonance imaging (MRI) of the spine is a sensitive investigation, which not only provides detailed images of the spinal column but also adjacent spinal regions and para-vertebral organ systems. Such incidental findings (IF) can be asymptomatic but significant. The efficacy of whole spine T2 sagittal screening in providing additional information has been demonstrated in several spinal diseases but its routine use in patients with spinal degenerative diseases has not been studied...
January 21, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28110327/mortality-after-renal-allograft-failure-and-return-to-dialysis
#7
Amarpali Brar, Mariana Markell, Dimitre G Stefanov, Edem Timpo, Rahul M Jindal, Robert Nee, Nabil Sumrani, Devon John, Fasika Tedla, Moro O Salifu
INTRODUCTION: The outcomes of patients who fail their kidney transplant and return to dialysis (RTD) has not been investigated in a nationally representative sample. We hypothesized that variations in management of transplant chronic kidney disease stage 5 leading to kidney allograft failure (KAF) and RTD, such as access, nutrition, timing of dialysis, and anemia management predict long-term survival. METHODS: We used an incident cohort of patients from the United States Renal Data System who initiated hemodialysis between January 1, 2003 and December 31, 2008, after KAF...
January 21, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28110311/carotid-intima-media-thickness-score-positive-coronary-artery%C3%A2-calcium-score-and-incident-coronary-heart-disease-the-multi-ethnic-study-of-atherosclerosis
#8
Joseph F Polak, Moyses Szklo, Daniel H O'Leary
BACKGROUND: Common carotid artery and internal carotid artery intima-media thicknesses (IMT) are associated with coronary heart disease (CHD) and increase with age. Using age, sex, and race/ethnicity IMT percentiles may improve CHD prediction when added to Framingham risk factors and coronary artery calcium score. We study these possibilities in the Multi-Ethnic Study of Atherosclerosis (MESA), a multi-ethnic cohort of whites, Chinese, blacks, and Hispanics. METHODS AND RESULTS: IMT data were acquired in the age range 45 to 84 years...
January 21, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28110293/increased-use-of-oral-anticoagulants-in-patients-with-atrial-fibrillation-temporal-trends-from-2005-to-2015-in-denmark
#9
Kasper Gadsbøll, Laila Staerk, Emil Loldrup Fosbøl, Caroline Sindet-Pedersen, Anna Gundlund, Gregory Y H Lip, Gunnar Hilmar Gislason, Jonas Bjerring Olesen
AIM: The aim of this study is to examine temporal trends in the use oral anticoagulants (OAC) as stroke prophylaxis in patients with atrial fibrillation (AF) and to examine factors associated with OAC initiation. METHODS AND RESULTS: From Danish nationwide registries, we identified patients diagnosed with AF at Danish hospitals and outpatient clinics between January 2005 and June 2015. OAC initiation was assessed from prescription fills ±180 days from date of AF diagnosis...
January 21, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28110288/screening-for-seemingly-healthy-newborns-with-congenital-cytomegalovirus-infection-by-quantitative-real-time-polymerase-chain-reaction-using-newborn-urine-an-observational-study
#10
Akira Yamaguchi, Tsutomu Oh-Ishi, Takashi Arai, Hideaki Sakata, Nodoka Adachi, Satoshi Asanuma, Eiji Oguma, Hirofumi Kimoto, Jiro Matsumoto, Hidetoshi Fujita, Tadashi Uesato, Jutaro Fujita, Ken Shirato, Hideki Ohno, Takako Kizaki
OBJECTIVE: Approximately 8-10% of newborns with asymptomatic congenital cytomegalovirus (cCMV) infection develop sensorineural hearing loss (SNHL). However, the relationship between CMV load, SNHL and central nervous system (CNS) damage in cCMV infection remains unclear. This study aimed to examine the relationship between urinary CMV load, SNHL and CNS damage in newborns with cCMV infection. STUDY DESIGN: The study included 23 368 newborns from two maternity hospitals in Saitama Prefecture, Japan...
January 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28110287/aspirin-to-inhibit-sepsis-antisepsis-randomised-controlled-trial-protocol
#11
Damon P Eisen, Elizabeth M Moore, Karin Leder, Jessica Lockery, Emma S McBryde, John J McNeil, David Pilcher, Rory Wolfe, Robyn L Woods
INTRODUCTION: Sepsis is a leading global cause of morbidity and mortality, and is more common at the extremes of age. Moreover, the cost of in-hospital care for elderly patients with sepsis is significant. There are indications from experimental and observational studies that aspirin may reduce inflammation associated with infection. This paper describes the rationale and design of the AspiriN To Inhibit SEPSIS (ANTISEPSIS) trial, a substudy of ASPirin in Reducing Events in the Elderly (ASPREE)...
January 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28110284/injuries-caused-by-pets-in-asian-urban-households-a-cross-sectional-telephone-survey
#12
Emily Y Y Chan, Yang Gao, Liping Li, Po Yi Lee
OBJECTIVES: Little is known about pet-related injuries in Asian populations. This study primarily aimed to investigate the incidence rate of pet-related household injuries in Hong Kong, an urban Chinese setting. SETTING: Cantonese-speaking non-institutionalised population of all ages in Hong Kong accessible by telephone land-line. PARTICIPANTS: A total of 43 542 telephone numbers were dialled and 6570 residents successfully completed the interviews...
January 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28110281/incidence-risk-factors-and-risk-prediction-of-hospital-acquired-suspected-adverse-drug-reactions-a-prospective-cohort-of-ugandan-inpatients
#13
Ronald Kiguba, Charles Karamagi, Sheila M Bird
OBJECTIVES: To determine the incidence and risk factors of hospital-acquired suspected adverse drug reactions (ADRs) among Ugandan inpatients. We also constructed risk scores to predict and qualitatively assess for peculiarities between low-risk and high-risk ADR patients. METHODS: Prospective cohort of consented adults admitted on medical and gynaecological wards of the 1790-bed Mulago National Referral Hospital. Hospital-acquired suspected ADRs were dichotomised as possible (possible/probable/definite) or not and probable (probable/definite) or not, using the Naranjo scale...
January 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28110254/leptomeningeal-carcinomatosis-in-non-small-cell-lung-cancer-patients-a-continuing-challenge-in-the-personalized-treatment-era
#14
REVIEW
J Remon, E Le Rhun, B Besse
Leptomeningeal metastasis is a fatal manifestation seen in advanced cancer patients. Its incidence is increasing, reaching 3.8% in molecularly unselected non-small cell lung cancer patients and up to 5% and 9% in ALK-rearranged and EGFR-mutant lung cancer patients, respectively. The prognosis remains poor despite systemic treatment, intrathecal chemotherapy, radiation therapy and personalized treatments in molecularly selected patients. However, new therapies with improved cerebral-spinal fluid penetration have been developed for subgroups of molecular selected patients indicating they could be promising therapeutic options for managing leptomeningeal disease...
December 30, 2016: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28110238/pre-pregnancy-weight-change-and-incidence-of-gestational-diabetes-mellitus-a-finding-from-a-prospective-cohort-study
#15
Akilew Awoke Adane, Leigh R Tooth, Gita D Mishra
AIMS: In a population-based cohort study we examined the associations between early adult pre-pregnancy weight change and the risk of gestational diabetes mellitus (GDM). METHODS: The study included 3111 women from the 1973-78 cohort of the Australian Longitudinal Study on Women's Health. These women have been surveyed regularly since 1996. Women without diabetes and GDM were followed-up between 2003 and 2012. Generalized estimating equations were used to assess the effect of baseline (1996, mean age 20years) and pre-pregnancy body mass index (BMI) and the pre-pregnancy weight changes on the incidence of GDM...
January 11, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28110235/relationship-between-expression-of-vascular-endothelial-growth-factor-and-the-proliferation-of-prolactinomas
#16
Nan Li Ya, ZhiQuan Jiang
OBJECTIVE: Prolactinomas are the most common functional hormone-producing pituitary lesions, accounting for 30-40% of all pituitary tumors, while in autopsy series their incidence reaches 50%. However, patients with prolactinoma had a higher recurrence percentage and rate than patients with acromegaly or Cushing's disease. Furthermore, prolactinomas have the highest rate of recurrence post-surgery as compared with other pituitary adenomas. At present, this behavior of prolactinoma is largely unexplained, but may be related to definition of cure, or to more frequent microscopic tumor infiltration into normal pituitary tissue, which is not removed at surgery...
December 14, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28110205/a-systematic-review-of-randomized-controlled-trials-of-interventions-designed-to-decrease-child-abuse-in-high-risk-families
#17
Elizabeth J Levey, Bizu Gelaye, Paul Bain, Marta B Rondon, Christina P C Borba, David C Henderson, Michelle A Williams
Child abuse is a global problem, and parents with histories of childhood abuse are at increased risk of abusing their offspring. The objective of this systematic review is to provide a clear overview of the existing literature of randomized controlled trials evaluating the effectiveness of interventions to prevent child abuse. PubMed, PsychINFO, Web of Science, Sociological Abstracts, and CINAHL were systematically searched and expanded by hand search. This review includes all randomized controlled trials (RCTs) of interventions designed to prevent abuse among mothers identified as high-risk...
January 19, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28110186/numb-chin-syndrome-as-a-sign-of-mandibular-metastasis-a-case-report
#18
Thomas Aerden, Koenraad Grisar, Patrick Neven, Esther Hauben, Constantinus Politis
INTRODUCTION: Metastasis to the oral cavity can be located in both the soft and bony tissues and comprise only 1% of all oral malignancies; however, it is clinically significant because it indicates widespread metastatic disease and an unfavorable prognosis. A numb chin is an important presentation of oral metastasis, but other dental and systemic pathology may be involved. PRESENTATION OF CASE: We present the case of a 54-year-old woman who presented with numb chin syndrome 8 years after a diagnosis of primary breast carcinoma...
January 4, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28110122/17%C3%AE-estradiol-enhances-sulforaphane-cardioprotection-against-oxidative-stress
#19
Cristina Angeloni, Gabriella Teti, Maria Cristina Barbalace, Marco Malaguti, Mirella Falconi, Silvana Hrelia
The lower incidence of ischemic heart disease in female with respect to male gender suggests the possibility that female sex hormones could have specific effects in cardiovascular protection. 17β-Estradiol is the predominant premenopausal circulating form of estrogen and has a protective role on the cardiovascular system. Recent evidences suggest that gender can influence the response to cardiovascular medications; therefore, we hypothesized that sex hormones could also modulate the cardioprotective effects of nutraceutical compounds, such as the isothiocyanate sulforaphane, present in Brassica vegetables...
January 12, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28110098/clinical-manifestations-of-helicobacter-pylori-negative-gastritis
#20
Seiji Shiota, Aaron P Thrift, Linda Green, Rajesh Shah, Gordana Verstovsek, Massimo Rugge, David Y Graham, Hashem B El-Serag
OBJECTIVES: There are data to suggest the existence of non-H. pylori gastritis. However, the risk factors and clinical course for H. pylori-negative gastritis remain unclear. We aimed to examine the prevalence and determinants of H. pylori-negative gastritis in a large multiethnic clinical population. METHOD: We conducted a cross-sectional study among patents scheduled for an elective esophagastroduodenoscopy or attending selected primary care clinics and eligible for screening colonoscopy at a single VA medical center...
January 18, 2017: Clinical Gastroenterology and Hepatology
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