keyword
https://read.qxmd.com/read/38147013/unusual-onset-of-graves-disease-associated-with-thymic-hyperplasia-in-a-5-year-old-girl-with-congenital-bilateral-clinical-anophthalmia-diagnostic-and-therapeutic-challenges
#21
Rania Ben Rabeh, Ahmed Bouzidi, Rim Hamdi, Nada Missaoui, Olfa Bouyahia, Sonia Mazigh, Samir Boukthir
OBJECTIVES: Graves' disease (GD) is a rare auto-immune disorder in pediatric population. The association between GD and thymic hyperplasia was rarely reported in children. Diagnosis and management of GD are challenging in children. CASE PRESENTATION: This report presents the case of a 5-year-old girl with a personal history of asthma and congenital bilateral isolated clinical anophthalmia who presented with acute congestive heart failure, sinus tachycardia and atypical signs of orbitopathy with edema and erythema of the lower right eyelid and excessive tearing...
December 27, 2023: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://read.qxmd.com/read/38146264/asthmalitis-diagnostic-variability-of-asthma-and-bronchiolitis-in-children-24-months
#22
JOURNAL ARTICLE
Patrick S Walsh, Wendi-Jo Wendt, Matthew J Lipshaw
BACKGROUND AND OBJECTIVES: Bronchiolitis and asthma have similar acute clinical presentations in young children yet have opposing treatment recommendations. We aimed to assess the role of age and other factors in the diagnosis of bronchiolitis and asthma in children <24 months of age. METHODS: We conducted a retrospective cross-sectional analysis of the Pediatric Health Information System database. We included children aged <2 years diagnosed with bronchiolitis, asthma, wheeze, or bronchospasm in emergency department or hospital encounters from 2017 to 2021...
December 26, 2023: Hospital Pediatrics
https://read.qxmd.com/read/38131521/the-impact-of-maternal-hyperemesis-gravidarum-on-early-childhood-respiratory-morbidity
#23
JOURNAL ARTICLE
Guy Hazan, Eyal Sheiner, Inbal Golan-Tripto, Aviv Goldbart, Ruslan Sergienko, Tamar Wainstock
BACKGROUND: Lung maldevelopment due to in-utero events may potentially cause respiratory morbidity during childhood. Maternal nutritional status during pregnancy is critical for lung development. This study is contributing to the understanding of the interplay between maternal nutrition status during pregnancy, fetal lung development and the risk for respiratory diseases in early life. RESEARCH QUESTION: To investigate the association between maternal hyperemesis gravidarum (HG) during pregnancy and respiratory morbidity in the offspring's early childhood...
December 22, 2023: Pediatric Pulmonology
https://read.qxmd.com/read/38112414/impact-of-a-discharge-prescription-for-dexamethasone-on-outcomes-of-children-treated-in-the-emergency-department-for-acute-asthma-exacerbations
#24
JOURNAL ARTICLE
Melisa S Tanverdi, Nidhya Navanandan, Savannah Brackman, Lorel Huber, Jan Leonard, Rakesh D Mistry
OBJECTIVE: To evaluate dexamethasone prescribing practices, patient adherence, and outcomes by dosing regimen in children with acute asthma discharged from the emergency department (ED). STUDY DESIGN: Prospective study of children 2-18 years treated with dexamethasone for acute asthma prior to discharge from an urban, tertiary care ED between 2018 and 2022. Demographics, clinical characteristics, ED treatment, and discharge prescriptions were collected via chart review...
December 19, 2023: Journal of Asthma
https://read.qxmd.com/read/38111626/expert-group-recommendation-on-inhaled-mucoactive-drugs-in-pediatric-respiratory-diseases-an-indian-perspective
#25
REVIEW
Meenu Singh, Sneha Varkki, Ilin Kinimi, Rashmi R Das, Jagdish Prasad Goyal, Mushtaq Bhat, Rajeshwar Dayal, Pawan Kalyan, Jitender Gairolla, Indu Khosla
BACKGROUND: Currently, there are no guidelines or consensus statements about the usage of inhaled mucoactive drugs in pediatric respiratory disease conditions from an Indian perspective. OBJECTIVE: To develop a practical consensus document to help pediatricians in clinical decision-making when choosing an appropriate mucoactive drug for the management of specific respiratory disease conditions. METHODS: A committee of nine experts with significant experience in pediatric respiratory disease conditions and a microbiological expert constituted the panel...
2023: Frontiers in Pediatrics
https://read.qxmd.com/read/38088231/lung-function-assessment-in-children-with-long-covid-syndrome
#26
JOURNAL ARTICLE
Francesco Sansone, Paola Di Filippo, Daniele Russo, Laura Sgrazzutti, Sabrina Di Pillo, Francesco Chiarelli, Marina Attanasi
INTRODUCTION: A significant percentage of patients who survived the Coronavirus Infection Disease 2019 (COVID-19) showed persistent general and respiratory symptoms even months after recovery. This condition, called Post-Acute Sequelae of COVID-19 or Long-Covid syndrome (LCS), has been described also in children with positive history for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Little is known about the pathophysiologic mechanisms underlying this syndrome...
December 13, 2023: Pediatric Pulmonology
https://read.qxmd.com/read/38065283/post-discharge-remote-patient-monitoring-for-children-hospitalized-with-acute-asthma-exacerbations
#27
JOURNAL ARTICLE
Jessica Walters, Kylee Denker, Sarah Curry, Mary C Burkhardt
No abstract text is available yet for this article.
December 6, 2023: Academic Pediatrics
https://read.qxmd.com/read/38058471/decreasing-icu-and-hospital-length-of-stay-through-a-standardized-respiratory-therapist-driven-electronic-clinical-care-pathway-for-status-asthmaticus
#28
JOURNAL ARTICLE
Merrick Lopez, Michele Wilson, Ekua Cobbina, Danny Kaufman, Julie Fluitt, Michele Grainger, Robert Ruiz, Gulixian Abudukadier, Michael Tiras, Bronwyn Carlson, Jeane Spaid, Kim Falsone, Invest Cocjin, Anthony Moretti, Chad Vercio, Cynthia Tinsley, Harsha K Chandnani, Carlos Samayoa, Carissa Cianci, James Pappas, Nancy Y Chang
INTRODUCTION: Status asthmaticus (SA) is a cause of many pediatric hospitalizations. This study sought to evaluate how a standardized asthma care pathway (ACP) in the electronic medical record impacted the length of stay (LOS). METHODS: An interdisciplinary team internally validated a standardized respiratory score for patients admitted with SA to a 25-bed pediatric intensive care unit (PICU) at a tertiary children's hospital. The respiratory score determined weaning schedules for albuterol and steroid therapies...
2023: Pediatric Quality & Safety
https://read.qxmd.com/read/38055113/risk-factors-for-long-covid-in-children-and-adolescents-a-systematic-review-and-meta-analysis
#29
REVIEW
Daniel G Rayner, Elaine Wang, Cloris Su, Om D Patel, Stephanie Aleluya, Alessandra Giglia, Evelyn Zhu, Maha Siddique
BACKGROUND: The long-term sequelae of COVID-19 in children and adolescents remain poorly understood and characterized. This systematic review and meta-analysis sought to summarize the risk factors for long COVID in the pediatric population. METHODS: We searched six databases from January 2020 to May 2023 for observational studies reporting on risk factors for long COVID or persistent symptoms those were present 12 or more weeks post-infection using multivariable regression analyses...
February 2024: World Journal of Pediatrics: WJP
https://read.qxmd.com/read/38044452/air-pollution-after-acute-bronchiolitis-is-a-risk-factor-for-preschool-asthma-a-nested-case-control-study
#30
JOURNAL ARTICLE
Hao-Wei Chung, Hui-Min Hsieh, Chung-Hsiang Lee, Yi-Ching Lin, Yu-Hsiang Tsao, Ming-Chu Feng, Chih-Hsing Hung
BACKGROUND: Acute bronchiolitis and air pollution are both risk factor of pediatric asthma. This study aimed to assess subsequent exposure to air pollutants related to the inception of preschool asthma in infants with acute bronchiolitis. This study aimed to assess subsequent exposure to air pollutants related to the inception of preschool asthma in infants with acute bronchiolitis. METHODS: A nested case-control retrospective study was performed at the Kaohsiung Medical University Hospital systems between 2009 and 2019...
December 4, 2023: Environmental Health
https://read.qxmd.com/read/38019615/noninvasive-neurally-adjusted-ventilatory-assist-in-infants-with-bronchiolitis-respiratory-outcomes-in-a-single-center-retrospective-cohort-2016-2018
#31
JOURNAL ARTICLE
Alex Lepage-Farrell, Laurence Tabone, Virginie Plante, Atsushi Kawaguchi, Joshua Feder, Sally Al Omar, Guillaume Emeriaud
OBJECTIVES: To describe our experience of using noninvasive neurally adjusted ventilatory assist (NIV-NAVA) in infants with bronchiolitis, its association with the evolution of respiratory effort, and PICU outcomes. DESIGN: Retrospective analysis of a prospectively curated, high-frequency electronic database. SETTING: A PICU in a university-affiliated maternal-child health center in Canada. PATIENTS: Patients younger than 2 years old who were admitted with a diagnosis of acute bronchiolitis and treated with NIV-NAVA from October 2016 to June 2018...
March 1, 2024: Pediatric Critical Care Medicine
https://read.qxmd.com/read/37988259/inhaled-nitric-oxide-in-acute-bronchiolitis-a-systematic-review-and-meta-analysis
#32
JOURNAL ARTICLE
Ilari Kuitunen, Marjo Renko
OBJECTIVE: Until date there is lack of effective therapies in acute bronchiolitis in infants. The aim was to analyze inhaled nitric oxide efficacy in acute bronchiolitis. DESIGN: Systematic review and meta-analysis of randomized controlled trials. SETTING: Pediatric specialized healthcare. PATIENTS: All infants (age less than 2 years) having acute bronchiolitis, which requires emergency room visit or hospitalization...
November 21, 2023: Pediatric Pulmonology
https://read.qxmd.com/read/37971472/emergency-nursing-based-on-pews-can-improve-the-condition-of-children-with-acute-asthma
#33
JOURNAL ARTICLE
Li Wang, Shaomin Zheng, Qing Wang, Junyan Ma, Suyan Zhang, Jianping Ma, Ying Ma, Chunrong Chang, Yuhui Cui
OBJECTIVE: The objective of this study is to investigate the effects of emergency nursing interventions, specifically those based on the Pediatric Early Warning Score (PEWS), on children diagnosed with acute asthma, to promote the recovery of children with asthma and improve the quality of care for children with asthma. METHODS: A total of 80 children, Acute asthma attacks under the age of 12, diagnosed with acute asthma and admitted to the Emergency Department of Hebei Children's Hospital between June 2018 and June 2019 were selected as participants for this study...
November 17, 2023: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/37969160/adolescent-with-diabetic-ketoacidosis-hypothermia-and-pneumomediastinum
#34
JOURNAL ARTICLE
Steven Millner, Courtney Devlin
AUDIENCE: The target audience of this simulation is emergency medicine residents and medical students. The simulation is based on a real case of a 12-year-old male who presented obtunded with shortness of breath and hypothermia who was ultimately diagnosed with diabetic ketoacidosis (DKA) and pneumomediastinum. This case highlights the diagnosis and management of an adolescent with new onset diabetic ketoacidosis and pneumomediastinum with deterioration of status, as well as important ventilator settings if intubation is required in the setting of diabetic ketoacidosis...
October 2023: Journal of education & teaching in emergency medicine
https://read.qxmd.com/read/37968074/core-outcomes-and-factors-influencing-the-experience-of-care-for-children-with-severe-acute-exacerbations-of-asthma-a-qualitative-study
#35
JOURNAL ARTICLE
Simon Craig, Yao Xu, Kael Robas, Ricardo Iramain, Adriana Yock-Corrales, Manuel E Soto-Martinez, Pedro Rino, Maria Belen Alvarez Ricciardi, Sofia Piantanida, Sanjay Mahant, Peter Odion Ubuane, Olatunde Odusote, Maria Kwok, Michael D Johnson, Natalia Paniagua, Javier Benito Fernandez, Gene Y Ong, Mark D Lyttle, Jin Gong, Damian Roland, Stuart R Dalziel, Gillian M Nixon, Colin V E Powell, Andis Graudins, Franz E Babl
OBJECTIVE: To identify the outcomes considered important, and factors influencing the patient experience, for parents and caregivers of children presenting to hospital with a severe acute exacerbation of asthma. This work contributes to the outcome-identification process in developing a core outcome set (COS) for future clinical trials in children with severe acute asthma. DESIGN: A qualitative study involving semistructured interviews with parents and caregivers of children who presented to hospital with a severe acute exacerbation of asthma...
November 2023: BMJ Open Respiratory Research
https://read.qxmd.com/read/37954776/assessment-of-the-relation-between-asthma-severity-and-serum-vitamin-d-levels-a-cross-sectional-study
#36
JOURNAL ARTICLE
Navjot Kaur, Vipul Kumar, Jagjot Singh, Hritvik Jain, Paras Paras, Nirmaljeet Kaur, Ashwani K Sareen
Introduction Vitamin D3's importance for bone health in children and its potential role beyond musculocutaneous health is an ongoing area of research. This study assesses vitamin D3 deficiency prevalence in asthmatic children and its correlation with asthma cases and healthy controls.  Methods This cross-sectional study was conducted in a tertiary care hospital in Punjab, India among children between 5 and 15 years of age. Fifty children diagnosed with "bronchial asthma" who were under follow-up in the asthma clinic in outpatient and inpatient patients were enrolled as cases...
October 2023: Curēus
https://read.qxmd.com/read/37927297/developing-a-nurse-led-salbutamol-weaning-pathway-for-children-and-young-people-with-asthma-or-viral-induced-wheeze
#37
JOURNAL ARTICLE
Kate O'Hagan, Annette Hall
Acute asthma exacerbations and viral-induced wheeze are common presenting complaints on one general paediatric ward in a tertiary children's hospital in England. An inhaled beta 2 agonist, such as salbutamol, is the first-line treatment for these children and young people and they have frequent clinician reviews for salbutamol weaning before discharge. However, the informal salbutamol weaning practices used by nurses, as well as challenges in the recruitment and retention of paediatric trainee doctors, led to the development of a nurse-led salbutamol weaning pathway as a quality improvement project...
November 6, 2023: Nursing Children and Young People
https://read.qxmd.com/read/37903233/changes-in-health-care-utilization-during-the-first-2-years-of-massachusetts-medicaid-accountable-care-organizations
#38
JOURNAL ARTICLE
Meagan J Sabatino, Eric O Mick, Arlene S Ash, Jay Himmelstein, Matthew J Alcusky
On March 1, 2018, the Massachusetts Medicaid and Children's Health Insurance Program (MassHealth) launched an ambitious accountable care organization (ACO) program that sought to integrate care across the physical, behavioral, functional, and social services continuum while holding ACOs accountable for cost and quality. The study objective was to describe changes in health care utilization among MassHealth members during the pre-ACO baseline (2015-2017) and post-implementation periods (2018 and 2019). Using MassHealth administrative data, the authors conducted a repeated cross-sectional study of MassHealth members enrolled in ACOs during 2015-2019...
October 30, 2023: Population Health Management
https://read.qxmd.com/read/37873951/acute-bronchiolitis-the-less-the-better
#39
JOURNAL ARTICLE
Fabrizio Virgili, Raffaella Nenna, Greta Di Mattia, Luigi Matera, Laura Petrarca, Maria Giulia Conti, Fabio Midulla
BACKGROUND: Acute bronchiolitis is a viral infection of the lower respiratory tract affecting infants aged under 12 months, variably presenting with respiratory distress, diffuse crackles and inflammatory wheezing. The main causative agent is Respiratory Syncytial Virus (RSV). The diagnosis is clinical and treatment mainly supportive. Despite the availability of more than 30 international guidelines, consistent management recommendations are lacking and considerable variability in patients' care persists among different providers...
October 16, 2023: Current Pediatric Reviews
https://read.qxmd.com/read/37868710/outcomes-of-invasive-and-noninvasive-ventilation-in-a-haitian-emergency-department
#40
JOURNAL ARTICLE
Anna P Fang, Marie Cassandre Edmond, Regan H Marsh, Manouchka Normil, Nivedita Poola, Sherley Jean Michel Payant, Pierre Ricot Luc, Natalie Strokes, Manise Calixte, Linda Rimpel, Shada A Rouhani
BACKGROUND: Limited data exist on the outcomes of patients requiring invasive ventilation or noninvasive positive pressure ventilation (NIPPV) in low-income countries. To our knowledge, no study has investigated this topic in Haiti. OBJECTIVES: We describe the clinical epidemiology, treatment, and outcomes of patients requiring NIPPV or intubation in an emergency department (ED) in rural Haiti. METHODS: This is an observational study utilizing a convenience sample of adult and pediatric patients requiring NIPPV or intubation in the ED at an academic hospital in central Haiti from January 2019-February 2021...
2023: Annals of Global Health
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