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Pediatric acute asthma

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https://www.readbyqxmd.com/read/29164080/the-incidence-and-short-term-outcomes-of-acute-respiratory-illness-with-cough-in-children-from-a-socioeconomically-disadvantaged-urban-community-in-australia-a-community-based-prospective-cohort-study
#1
Kerry K Hall, Anne B Chang, Jennie Anderson, Daniel Arnold, Vikas Goyal, Melissa Dunbar, Michael Otim, Kerry-Ann F O'Grady
Background: Acute respiratory illnesses with cough (ARIwC) are predominant causes of morbidity in Australian Indigenous children; however, data on disease burden in urban communities are scarce. This study aimed to determine the incidence of ARIwC, the predictors of recurrent (≥4 episodes) ARIwC, and development of chronic cough following an ARIwC in urban, predominantly Indigenous, children aged <5 years from northern Brisbane, Australia. Methods: Prospective cohort study of children aged <5 years registered with a primary healthcare center...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29159184/acute-asthma-in-the-pediatric-emergency-department-infections-are-the-main-triggers-of-exacerbations
#2
Arianna Dondi, Elisabetta Calamelli, Valentina Piccinno, Giampaolo Ricci, Ilaria Corsini, Carlotta Biagi, Marcello Lanari
Background: Asthma exacerbations are a common reason for Emergency Department (ED) visits in children. Aim: To analyze differences among age groups in terms of triggering factors and seasonality and to identify those with higher risk of severe exacerbations. Methods: We retrospectively revised the files of children admitted for acute asthma in 2016 in our Pediatric ED. Results: Visits for acute asthma were 603/23197 (2...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29153065/-genotypes-of-rhinoviruses-in-children-and-adults-patients-with-acute-respiratory-tract-infections
#3
Eda Demirkan, Sevin Kırdar, Emel Ceylan, Ayşe Yenigün, İmran Kurt Ömürlü
Rhinovirus (RV) is one of the most frequent causative agent of acute respiratory tract infections in the world. The virus may cause a mild cold, as well as more serious clinical symptoms in patients with immune system deficiency or comorbidities. Rhinoviruses have been identified by molecular methods under three types: RV-A, RV-B and RV-C. In most of the cases, it was reported that RV-A and RV-C were related with lower respiratory tract infections and asthma exacerbations, while RV-B was rarely reported in lower respiratory tract infections...
October 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/29137905/emergency-department-chest-radiography-for-children-with-asthma-exacerbation-is-infrequently-associated-with-change-of-management
#4
Evan H Allie, Henry E Dingle, William N Johnson, Jeffrey R Birnbaum, Melissa A Hilmes, Sudha P Singh, Donald H Arnold
BACKGROUND: Acute asthma exacerbations (AAE) account for many Pediatric Emergency Department (PED) visits. Chest radiography (CXR) is often performed in these patients to identify practice-changing findings such as pneumonia (PNA). Limited knowledge exists to balance the cost and radiation dose of CXR with expected yield of clinically meaningful information. OBJECTIVE: To determine in children with AAE with CXR, whether patient characteristics are associated with radiographic PNA; and significant practice change by initiation of antibiotic...
October 6, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29134776/acute-chest-syndrome-among-children-hospitalized-with-vaso-occlusive-crisis-a-nationwide-study-in-the-united-states
#5
Takuto Takahashi, Yusuke Okubo, Atsuhiko Handa
PURPOSE: Acute chest syndrome (ACS) is a common complication among pediatric inpatients with sickle cell disease and vaso-occlusive crisis (VOC). However, little is known about the factors associated with ACS complication. The present study assessed the epidemiological features of children hospitalized with VOC and ascertained factors associated with ACS complication. METHODS: Hospital discharge records of patients with VOC aged <20 years were obtained for the years 2003, 2006, 2009, and 2012 from the Kids' Inpatient Database...
November 14, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29107465/forced-expiratory-values-in-1-second-corresponding-to-pediatric-respiratory-assessment-measure-and-acute-asthma-intensity-research-score-values-during-pediatric-acute-asthma-exacerbations
#6
Donald H Arnold, David P Johnson, Connie L Yang, Tina V Hartert
No abstract text is available yet for this article.
October 26, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29044803/impact-of-pediatric-obesity-on-acute-asthma-exacerbation-in-japan
#7
Yusuke Okubo, Nobuaki Michihata, Koichi Yoshida, Naho Morisaki, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga
BACKGROUND: Asthma and obesity are common health problems in children. This study investigated the impact of obesity on children hospitalized with acute asthma exacerbation. METHODS: We obtained the hospital discharge records of inpatients aged 3-8 years with a diagnosis of asthma using a national inpatient database in Japan. The patients were classified into underweight, normal weight, overweight, and obese groups using weight for height and body mass index for age provided by the World Health Organization...
October 18, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29028809/nasal-dna-methylation-differentiates-corticosteroid-treatment-response-in-pediatric-asthma-a-pilot-study
#8
Xue Zhang, Jocelyn M Biagini Myers, Veda K Yadagiri, Ashley Ulm, Xiaoting Chen, Matthew T Weirauch, Gurjit K Khurana Hershey, Hong Ji
BACKGROUND: Treatment response to systemic corticosteroid in asthmatic children is heterogeneous and may be mediated by epigenetic mechanism(s). We aim to identify DNA methylation (DNAm) changes responsive to steroid, and DNAm biomarkers that distinguish treatment response. MATERIALS AND METHODS: We followed 33 children (ages 5-18) presenting to the Emergency Department (ED) for asthma exacerbation. Based on whether they met discharge criteria in ≤24 hours, participants were grouped into good and poor responders to steroid treatment...
2017: PloS One
https://www.readbyqxmd.com/read/28991947/regional-variation-in-standardized-costs-of-care-at-children-s-hospitals
#9
Jennifer A Jonas, Samir S Shah, Isabella Zaniletti, Matthew Hall, Jeffrey D Colvin, Laura M Gottlieb, Marion R Sills, Jessica Bettenhausen, Rustin B Morse, Michelle L Macy, Evan S Fieldston
OBJECTIVE: (1) To evaluate regional variation in costs of care for 3 inpatient pediatric conditions, (2) assess potential drivers of variation, and (3) estimate cost savings from reducing variation. DESIGN/SETTING: Retrospective cohort study of hospitalizations for asthma, diabetic ketoacidosis (DKA), and acute gastroenteritis (AGE) at 46 children<s hospitals from October 2014 to September 2015. MEASUREMENTS: Variation in trimmed standardized costs were assessed within and across regions...
October 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28941390/severe-forms-of-food-allergy
#10
REVIEW
Emanuel Sarinho, Maria das Graças Moura Lins
OBJECTIVES: To guide the diagnostic and therapeutic management of severe forms of food allergy. DATA SOURCES: Search in the Medline database using the terms "severe food allergy," "anaphylaxis and food allergy," "generalized urticaria and food allergy," and "food protein-induced enterocolitis syndrome" in the last ten years, searching in the title, abstract, or keyword fields. SUMMARY OF DATA: Food allergy can be serious and life-threatening...
November 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28927681/adapting-an-evidence-based-pediatric-acute-asthma-exacerbation-severity-assessment-tool-for-pediatric-primary-care
#11
Anne T Magpuri, Jane K Dixon, Ruth McCorkle, Angela A Crowley
INTRODUCTION: The purposes of this project were (a) to examine criteria derived from evidence-based pediatric acute asthma exacerbation assessment tools, asthma scores, and the acute asthma prediction rule validated and used in the emergency department and (b) to adapt these criteria for pediatric primary care. METHOD: The three stages of the project included (a) identification of criteria in a literature review, (b) validation of the criteria by an expert panel, and (c) adaptation of the criteria in the design of an assessment tool...
September 16, 2017: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/28891268/pediatric-respiratory-tract-diseases-chronological-trends-and-perspectives
#12
Houda Ben Ayed, Sourour Yaïch, Maïssa Ben Jmaa, Jihene Jedidi, Mariem Ben Hmida, Maroua Trigui, Mondher Kassis, Raouf Karray, Yosra Mejdoub, Habib Feki, Jamel Damak
BACKGROUND: The aim of this study was to describe the epidemiological profile of childhood respiratory tract diseases (RTD) in the region of Sfax, Tunisia, and to evaluate their trends over a 13 year period. METHODS: We conducted a retrospective study of all children hospitalized with RTD aged under 14 years. We collected data from the regional morbidity register of the university hospital of Sfax from 2003 to 2015. RESULTS: A total of 10 797 RTD patients were enrolled from 49 880 pediatric hospitalizations (21...
September 10, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28872981/sex-differences-in-outcomes-after-discharge-from-alberta-emergency-departments-for-asthma-a-large-population-based-study
#13
Rhonda J Rosychuk, Maria Ospina, Jingbin Zhang, Richard Leigh, Andrew Cave, Brian H Rowe
OBJECTIVE: Asthma exacerbations frequently result in emergency department (ED) visits. While sex differences have been identified in some asthma studies, there is a paucity of literature on sex differences in the ED setting, especially population-based ones. This study examines sex differences in important outcomes of patients discharged from EDs for acute asthma in Alberta, Canada. METHODS: Alberta residents aged from 2 to 55 years discharged from EDs with a primary diagnosis of asthma during 1999-2011 were identified from administrative databases from a single-payer health care system for the entire geographic region of Alberta...
September 5, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28816890/improving-timeliness-of-%C3%AE-agonist-and-corticosteroid-administration-in-patients-with-acute-wheezing
#14
Mandisa McIver, William Stoudemire, Cherrelle Smith-Ramsey, Mousumee Panigrahi, Christine Walsh-Kelly, Lori E Rutman
OBJECTIVE: Timely delivery of β-agonists and steroids to patients with acute recurrent wheezing is a key component of the National Heart, Lung, and Blood Institute recommended emergency department (ED) asthma care. We conducted an ED improvement initiative to standardize asthma care and improve time to treatments. METHODS: Our multidisciplinary team identified key contributing factors to timeliness, developed key driver diagrams, implemented and refined a management pathway, designed and executed rapid cycle improvements, and implemented interventions...
September 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28804700/abridged-version-of-the-awmf-guideline-for-the-medical-clinical-diagnostics-of-indoor-mould-exposure-s2k-guideline-of-the-german-society-of-hygiene-environmental-medicine-and-preventive-medicine-ghup-in-collaboration-with-the-german-association-of-allergists
#15
Gerhard A Wiesmüller, Birger Heinzow, Ute Aurbach, Karl-Christian Bergmann, Albrecht Bufe, Walter Buzina, Oliver A Cornely, Steffen Engelhart, Guido Fischer, Thomas Gabrio, Werner Heinz, Caroline E W Herr, Jörg Kleine-Tebbe, Ludger Klimek, Martin Köberle, Herbert Lichtnecker, Thomas Lob-Corzilius, Rolf Merget, Norbert Mülleneisen, Dennis Nowak, Uta Rabe, Monika Raulf, Hans Peter Seidl, Jens-Oliver Steiß, Regine Szewszyk, Peter Thomas, Kerttu Valtanen, Julia Hurraß
This article is an abridged version of the AWMF mould guideline "Medical clinical diagnostics of indoor mould exposure" presented in April 2016 by the German Society of Hygiene, Environmental Medicine and Preventive Medicine (Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin, GHUP), in collaboration with the above-mentioned scientific medical societies, German and Austrian societies, medical associations and experts. Indoor mould growth is a potential health risk, even if a quantitative and/or causal relationship between the occurrence of individual mould species and health problems has yet to be established...
2017: Allergo Journal International
https://www.readbyqxmd.com/read/28757228/cluster-analysis-of-acute-care-use-yields-insights-for-tailored-pediatric-asthma-interventions
#16
Mahshid Abir, Aaron Truchil, Dawn Wiest, Daniel B Nelson, Jason E Goldstick, Paul Koegel, Marie M Lozon, Hwajung Choi, Jeffrey Brenner
STUDY OBJECTIVE: We undertake this study to understand patterns of pediatric asthma-related acute care use to inform interventions aimed at reducing potentially avoidable hospitalizations. METHODS: Hospital claims data from 3 Camden city facilities for 2010 to 2014 were used to perform cluster analysis classifying patients aged 0 to 17 years according to their asthma-related hospital use. Clusters were based on 2 variables: asthma-related ED visits and hospitalizations...
July 27, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28754601/magnesium-sulfate-infusion-for-acute-asthma-in-the-emergency-department
#17
REVIEW
Jose Enrique Irazuzta, Nicolas Chiriboga
OBJECTIVES: To describe the role of intravenous magnesium sulfate (MgSO4) as therapy for acute severe asthma in the pediatric emergency department (ED). SOURCE: Publications were searched in the PubMed and Cochrane databases using the following keywords: magnesium AND asthma AND children AND clinical trial. A total of 53 publications were retrieved using this criteria. References of relevant articles were also screened. The authors included the summary of relevant publications where intravenous magnesium sulfate was studied in children (age <18 years) with acute asthma...
November 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28745850/noninvasive-ventilation-for-patients-in-acute-respiratory-distress-an-update-digest
#18
Nikita Joshi, Molly K Estes, Kayla Shipley, Hyun-Chul Danny Lee, Milana Zaurova
Over the last 20 years, noninvasive ventilation (NIV) strategies have been used with increasing frequency. The ease of use of NIV makes it applicable to patients presenting in a variety of types of respiratory distress. In this review, the physiology of positive pressure ventilation is discussed, including indications, contraindications, and options for mask type and fit. Characteristics of patients who are most likely to benefit from NIV are reviewed, including those in respiratory distress from chronic obstructive pulmonary disease exacerbation and cardiogenic pulmonary edema...
February 22, 2017: Emergency Medicine Practice
https://www.readbyqxmd.com/read/28696803/thai-pediatricians-current-practice-toward-childhood-asthma
#19
Harutai Kamalaporn, Pongpan Chawalitdamrong, Aroonwan Preutthipan
BACKGROUND: Childhood asthma is a substantial health burden in Thailand. Due to a lack of pediatric respiratory specialists (pediatric pulmonologists and allergists; RS), most Thai children are cared for by general pediatricians (pediatric primary care providers (PCP)). OBJECTIVES: We investigated whether current practices of Thai pediatricians complied with asthma guidelines and compared practices (diagnosis and treatments) provided by PCP and RS. METHODS: A cross-sectional study was conducted using electronic surveys including four case scenarios of different asthma phenotypes distributed to Thai pediatricians...
July 11, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28667069/role-of-human-metapneumovirus-and-respiratory-syncytial-virus-in-asthma-exacerbations-where-are-we-now
#20
REVIEW
Penny A Rudd, Belinda J Thomas, Ali Zaid, Martin MacDonald, Keiko Kan-O, Michael S Rolph, Anand R Soorneedi, Philip G Bardin, Suresh Mahalingam
Since its discovery in 2001, human metapneumovirus (hMPV) has been identified as an important cause of respiratory tract infection in young children, second only to the closely related respiratory syncytial virus (RSV). Clinical evidence suggests that hMPV is associated with acute exacerbations of asthma in both children and adults, and may play a role in initiating asthma development in children. Animal models have demonstrated that airway hyperresponsiveness (AHR) and inflammation are triggered following hMPV infection, and hMPV is able to persist in vivo by inhibiting innate immune responses and causing aberrant adaptive responses...
July 15, 2017: Clinical Science (1979-)
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