keyword
https://read.qxmd.com/read/38481279/axillary-vein-as-an-alternative-venous-access-site-for-vv-ecmo-cannulation-a-case-report
#21
JOURNAL ARTICLE
Tao Pan, Xiaoyang Zhou, Jianneng Pan, Bixin Chen, Chang Xu, Zhaojun Xu, Pingping Dong, Tingting Yu
BACKGROUND: Ultrasound-guided percutaneous axillary vein cannulation can reduce cannulation failure and mechanical complications, is as safe and effective as internal jugular vein cannulation, and is superior to subclavian vein cannulation using landmark technique. As far, reports of venovenous extracorporeal membrane oxygenation (VV-ECMO) with percutaneous axillary vein cannulation are rare. CASE PRESENTATION: A 64-year-old man presenting with dyspnea and chest tightness after aspirating sewage was admitted to the emergency department...
March 13, 2024: Journal of Cardiothoracic Surgery
https://read.qxmd.com/read/38480756/preclinical-systolic-dysfunction-relating-to-ankle-brachial-index-among-high-risk-pad-population-with-preserved-left-ventricular-ejection-fraction
#22
JOURNAL ARTICLE
Yueh-Hung Lin, Kuo-Tzu Sung, Cheng-Ting Tsai, Yau-Huei Lai, Chi-In Lo, Fa-Chang Yu, Wei-Ran Lan, Ta-Chuan Hung, Jen-Yuan Kuo, Charles Jia-Yin Hou, Chih-Hsuan Yen, Ming-Cheng Peng, Hung-I Yeh, Ming-Ting Wu, Chung-Lieh Hung
Peripheral artery disease (PAD) shares common clinical risk factors, for example, endothelial dysfunction, with preserved ejection fraction (LVEF) heart failure (HFpEF). Whether PAD is associated with preclinical systolic dysfunction and higher HF risk among individuals presenting preserved LVEF remains uncertain. We retrospectively included outpatients with at least one known or established cardiovascular (CV) risk factor with LVEF ≥ 50%. Patients were categorized into high risk and low risk of developing PAD (PAD vs Non-PAD) by ankle-brachial index (ABI) (≤ 0...
March 14, 2024: Scientific Reports
https://read.qxmd.com/read/38480481/impact-of-epicardial-adipose-tissue-on-cardiac-function-and-morphology-in-patients-with-diastolic-dysfunction
#23
JOURNAL ARTICLE
Alexander Schulz, Sören J Backhaus, Torben Lange, Ruben Evertz, Shelby Kutty, Johannes T Kowallick, Gerd Hasenfuß, Andreas Schuster
AIMS: This study aimed to identify the impact of increased epicardial adipose tissue (EAT) and its regional distribution on cardiac function in patients with diastolic dysfunction. METHODS AND RESULTS: Sixty-eight patients with exertional dyspnoea (New York Heart Association ≥II), preserved ejection fraction (≥50%), and diastolic dysfunction (E/e' ≥ 8) underwent rest and stress right heart catheterization, transthoracic echocardiography, and cardiovascular magnetic resonance (CMR)...
March 13, 2024: ESC Heart Failure
https://read.qxmd.com/read/38479849/spontaneous-remission-without-steroid-therapy-in-isolated-cardiac-sarcoidosis-with-severe-left-ventricular-systolic-dysfunction
#24
JOURNAL ARTICLE
Takaya Ozawa, Kenji Goto, Katsuya Miura, Kazunari Kobayashi, Yuetsu Kikuta, Katsumasa Sato, Masahito Taniguchi, Shigeki Hiramatsu, Hideo Takebayashi, Seiichi Haruta
Spontaneous remission is often observed in extracardiac cases of sarcoidosis, such as skin sarcoidosis. However, for cardiac sarcoidosis (CS), the prognosis is unfavorable. Although corticosteroids are the first-line treatment for CS, data regarding the natural history of isolated CS are limited. We describe a rare case of isolated CS with severe left ventricular systolic dysfunction that improved without steroid therapy.
March 12, 2024: International Heart Journal
https://read.qxmd.com/read/38477934/pulmonary-vascular-disease-and-optical-coherence-tomography-imaging-in-patients-with-fontan-palliation
#25
JOURNAL ARTICLE
Marie-A Chaix, Réda Ibrahim, Jean-Claude Tardif, Colombe Roy, François-Pierre Mongeon, Annie Dore, Blandine Mondésert, Paul Khairy
INTRODUCTION: The Fontan procedure is the palliative procedure of choice for patients with single ventricle physiology. Pulmonary vascular disease (PVD) is an important contributor to Fontan circulatory failure. AREAS COVERED: We review the pathophysiology of PVD in patients with Fontan palliation and share our initial experience with optical coherence tomography (OCT) in supplementing standard hemodynamics in characterizing Fontan-associated PVD. In the absence of a sub-pulmonary ventricle, low pulmonary vascular resistance (PVR; ≤2 WU/m2 ) is required to sustain optimal pulmonary blood flow...
March 13, 2024: Expert Review of Cardiovascular Therapy
https://read.qxmd.com/read/38476290/the-role-of-detailed-medical-history-for-the-early-diagnosis-of-familial-bradycardia-in-a-patient-with-associated-atrial-fibrillation-case-report
#26
Andreea Ciacaru, Anna Tusa, Annamaria Magdas, Cristian Podoleanu
BACKGROUND: Bradycardia represents a frequent reason for medical presentation and has a complex aetiology, including genetic disorders, like LMNA mutation. LMNA mutation is responsible for laminopathies, including LMNA -cardiomyopathy. Cardiac involvement is prevalent and is linked to dilated cardiomyopathy associated with conduction block, which is anticipated by bradyarrhythmia and supraventricular tachyarrhythmia. LMNA mutation carriers have higher risk for sudden cardiac death (SCD), malignant ventricular tachycardia, and extreme bradycardia...
March 2024: European Heart Journal. Case Reports
https://read.qxmd.com/read/38476289/pathogenic-truncating-filamin-c-mutations-presenting-as-acute-myocarditis-a-case-series-with-insights-from-cardiac-magnetic-resonance-and-histological-analysis
#27
Apostolos Vrettos, Polyvios Demetriades, Martín Ortiz, Fernando Domínguez, Pablo García-Pavía, M Paz Suárez-Mier, Thomas Gossios, Konstantinos Savvatis
BACKGROUND: The exact mechanisms underlying the pathogenesis of myocarditis are not always understood, but there is emerging evidence to suggest that genetic factors may play a significant role. CASE SUMMARY: Herein, we present six cases in which clinical, biochemical, and cardiovascular magnetic resonance data were consistent with myocarditis, and genetic testing subsequently revealed pathogenic filamin C (FLNC) mutations. Three patients presented with ventricular arrhythmias, two with severe biventricular dysfunction, and two suffered sudden cardiac arrest...
March 2024: European Heart Journal. Case Reports
https://read.qxmd.com/read/38473911/mitochondrial-dysfunction-in-heart-failure-from-pathophysiological-mechanisms-to-therapeutic-opportunities
#28
REVIEW
Giovanna Gallo, Speranza Rubattu, Massimo Volpe
Mitochondrial dysfunction, a feature of heart failure, leads to a progressive decline in bioenergetic reserve capacity, consisting in a shift of energy production from mitochondrial fatty acid oxidation to glycolytic pathways. This adaptive process of cardiomyocytes does not represent an effective strategy to increase the energy supply and to restore the energy homeostasis in heart failure, thus contributing to a vicious circle and to disease progression. The increased oxidative stress causes cardiomyocyte apoptosis, dysregulation of calcium homeostasis, damage of proteins and lipids, leakage of mitochondrial DNA, and inflammatory responses, finally stimulating different signaling pathways which lead to cardiac remodeling and failure...
February 25, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38468721/outcomes-of-combo-therapy-for-severe-mitral-regurgitation-compared-with-transcatheter-edge-to-edge-repair
#29
JOURNAL ARTICLE
Hiroaki Yokoyama, Tobias Friedrich Ruf, Theresa Ann Maria Gößler, Martin Geyer, Julia Zirbs, Ben Luca Schwidtal, Thomas Münzel, Ralph Stephan von Bardeleben
BACKGROUND: There are different types of transcatheter mitral valve repair (TMVr) currently in clinical use, including leaflet approximation, annular cinching, and restoration of the chordal apparatus of the mitral valve (MV). While the concomitant combination (COMBO) therapy of mitral transcatheter edge-to-edge repair (M-TEER) with another TMVr concept has been proven feasible, potentially offering patient-tailored treatment for severe mitral regurgitation (MR), a comparison with M-TEER alone has not been made...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38467311/coronary-artery-tortuosity-and-spontaneous-coronary-artery-dissection-association-with-echocardiography-and-global-longitudinal-strain-fibromuscular-dysplasia-and-outcomes
#30
JOURNAL ARTICLE
Marysia S Tweet, Patricia A Pellikka, Rajiv Gulati, Benjamin R Gochanour, Zachary Barrett-O'Keefe, Claire E Raphael, Patricia J M Best, Sharonne N Hayes
BACKGROUND: The etiology and significance of coronary artery tortuosity (TCA) among patients with spontaneous coronary artery dissection (SCAD) is unknown. OBJECTIVES: The aim of this prospective imaging cohort study was to report echocardiographic findings and evaluate whether TCA correlates with cardiac anatomy and function among SCAD patients. Comorbidities including fibromuscular dysplasia (FMD) and outcomes were also assessed. METHODS: TCA was determined by coronary angiography performed during the diagnosis of SCAD, and cardiac structure and function was evaluated by prospective comprehensive echocardiography...
March 9, 2024: Journal of the American Society of Echocardiography
https://read.qxmd.com/read/38466531/yohimbine-treatment-alleviates-cardiac-inflammation-injury-and-improves-cardiac-hemodynamics-by-modulating-pro-inflammatory-and-oxidative-stress-indicators
#31
JOURNAL ARTICLE
Anjali Veeram, Taslim B Shaikh, Rajwinder Kaur, E Abhisheik Chowdary, Sai Balaji Andugulapati, Ramakrishna Sistla
Acute myocarditis, also known as myocardial inflammation, is a self-limited condition caused by systemic infection with cardiotropic pathogens, primarily viruses, bacteria, or fungi. Despite significant research, inflammatory cardiomyopathy exacerbated by heart failure, arrhythmia, or left ventricular dysfunction and it has a dismal prognosis. In this study, we aimed to evaluate the therapeutic effect of yohimbine against lipopolysaccharide (LPS) induced myocarditis in rat model. The anti-inflammatory activity of yohimbine was assessed in in-vitro using RAW 264...
March 11, 2024: Inflammation
https://read.qxmd.com/read/38465648/cardiovascular-management-of-patients-undergoing-hematopoietic-stem-cell-transplantation-from-pretransplantation-to-survivorship-a-scientific-statement-from-the-american-heart-association
#32
REVIEW
Salim S Hayek, Vlad G Zaha, Carmel Bogle, Anita Deswal, Amelia Langston, Seth Rotz, Alexi Vasbinder, Eric Yang, Tochukwu Okwuosa
Hematopoietic stem cell transplantation can cure various disorders but poses cardiovascular risks, especially for elderly patients and those with cardiovascular diseases. Cardiovascular evaluations are crucial in pretransplantation assessments, but guidelines are lacking. This American Heart Association scientific statement summarizes the data on transplantation-related complications and provides guidance for the cardiovascular management throughout transplantation. Hematopoietic stem cell transplantation consists of 4 phases: pretransplantation workup, conditioning therapy and infusion, immediate posttransplantation period, and long-term survivorship...
March 11, 2024: Circulation
https://read.qxmd.com/read/38465089/type-2-myocardial-infarction-caused-by-orthostatic-hypotension-with-post-transcatheter-aortic-valve-implantation-a-case-report
#33
Hitomi Tsuchida, Shiho Amano, Chiaki Sano, Ryuichi Ohta
This case report delineates the occurrence and management of type 2 myocardial infarction (MI) in an 89-year-old woman following transcatheter aortic valve implantation (TAVI). The patient, with a history of severe aortic stenosis, hypertension, dyslipidemia, and colorectal cancer, presented with nausea and significant hypotension. Initial assessments revealed elevated troponin levels, atrial fibrillation, and ST-segment depression, leading to a diagnosis of type 2 MI. This condition was attributed to the interplay between left ventricular hypertrophy, hypotension-induced dehydration, and increased myocardial oxygen demand...
February 2024: Curēus
https://read.qxmd.com/read/38464895/subcutaneous-anakinra-in-the-management-of-refractory-mis-c-in-france
#34
JOURNAL ARTICLE
Perrine Dusser, Alexandre Belot, Fanny Bajolle, Charlotte Kevorkian-Verguet, Ulrich Meinzer, Frédéric Huet, Soizic Tiriau, Isabelle Kone-Paut
INTRODUCTION: Multisystemic inflammatory syndrome in children (MIS-C) is a therapeutic emergency and can lead to myocardial dysfunction (17%-75%) and heart failure (52%-53%). Intravenous immunoglobulins (IVIG) and corticosteroids (CST) have been validated for the management of this condition. Recent reports suggest that an interleukin-1 (IL-1) receptor antagonist, namely anakinra, may be a valuable add-on to the 2019 novel coronavirus disease (COVID-19) treatment for refractory patients...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38464845/predicting-postoperative-systolic-dysfunction-in-mitral-regurgitation-ct-vs-echocardiography
#35
JOURNAL ARTICLE
Prajwal Reddy, Vidhu Anand, Prabhakar Rajiah, Nicholas B Larson, Jared Bird, James M Williams, Eric E Williamson, Rick A Nishimura, Juan A Crestanello, Arman Arghami, Jeremy D Collins, Alex Bratt
INTRODUCTION: Volume overload from mitral regurgitation can result in left ventricular systolic dysfunction. To prevent this, it is essential to operate before irreversible dysfunction occurs, but the optimal timing of intervention remains unclear. Current echocardiographic guidelines are based on 2D linear measurement thresholds only. We compared volumetric CT-based and 2D echocardiographic indices of LV size and function as predictors of post-operative systolic dysfunction following mitral repair...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38464828/ferroptosis-a-new-mechanism-in-diabetic-cardiomyopathy
#36
REVIEW
Zichong Song, Jingyi Wang, Lijun Zhang
Diabetic cardiomyopathy (DC) is a pathophysiologic condition caused by diabetes mellitus (DM) in the absence of coronary artery disease, valvular heart disease, and hypertension that can lead to heart failure (HF), manifesting itself in the early stages with left ventricular hypertrophy and diastolic dysfunction, with marked HF and decreased systolic function in the later stages. There is still a lack of direct evidence to prove the exact existence of DC. Ferroptosis is a novel form of cell death characterized by reactive oxygen species (ROS) accumulation and lipid peroxidation...
2024: International Journal of Medical Sciences
https://read.qxmd.com/read/38463680/differential-impact-of-fractional%C3%A2-flow%C3%A2-reserve-measured-after%C3%A2-coronary-stent-implantation-by-left-ventricular%C3%A2-dysfunction
#37
JOURNAL ARTICLE
Ki Hong Choi, Woochan Kwon, Doosup Shin, Seung-Hun Lee, Doyeon Hwang, Jinlong Zhang, Chang-Wook Nam, Eun-Seok Shin, Joon-Hyung Doh, Shao-Liang Chen, Tsunekazu Kakuta, Gabor G Toth, Zsolt Piroth, Abdul Hakeem, Barry F Uretsky, Yohei Hokama, Nobuhiro Tanaka, Hong-Seok Lim, Tsuyoshi Ito, Akiko Matsuo, Lorenzo Azzalini, Massoud A Leesar, Joost Daemen, Damien Collison, Carlos Collet, Bernard De Bruyne, Bon-Kwon Koo, Taek Kyu Park, Jeong Hoon Yang, Young Bin Song, Joo-Yong Hahn, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Joo Myung Lee
BACKGROUND: Both left ventricular systolic function and fractional flow reserve (FFR) are prognostic factors after percutaneous coronary intervention (PCI). However, how these prognostic factors are inter-related in risk stratification of patients after PCI remains unclarified. OBJECTIVES: This study evaluated differential prognostic implication of post-PCI FFR according to left ventricular ejection fraction (LVEF). METHODS: A total of 2,965 patients with available LVEF were selected from the POST-PCI FLOW (Prognostic Implications of Physiologic Investigation After Revascularization with Stent) international registry of patients with post-PCI FFR measurement...
March 2024: JACC Asia
https://read.qxmd.com/read/38463675/prognostic-importance-of-fractional-flow-reserve-and-left-ventricular-systolic-dysfunction-after-percutaneous%C3%A2-coronary-intervention
#38
EDITORIAL
Robert Sykes, Rebecca Hanna, Colin Berry
No abstract text is available yet for this article.
March 2024: JACC Asia
https://read.qxmd.com/read/38462807/evaluation-of-the-relationship-between-vitamin-d-deficiency-and-subclinical-cardiac-dysfunction-using-2d-3d-strain-echocardiography-in-healthy-people
#39
JOURNAL ARTICLE
Demet Menekse Gerede Uludag, Berna Imge Aydogan, Türkan Seda Tan, Aynur Acıbuca, Nazlı Turan, Rıfat Emral, Irem Dincer, Cetin Erol
AIM: Vitamin D deficiency has a high prevalence in the population and is highly associated with cardiovascular diseases. The aim of this study was to evaluate subclinical left ventricular (LV) function using strain analysis in healthy individuals with vitamin D deficiency. MATERIAL AND METHODS: 113 healthy volunteers were enrolled in the study (age, 44.1±7 yrs, 34 male). All volunteers underwent two-dimensional (2D) and three-dimensional (3D) speckle tracking echocardiography after conventional echocardiographic evaluation...
February 29, 2024: Kardiologiia
https://read.qxmd.com/read/38462693/5-hydroxytryptophan-acts-as-a-gap-junction-inhibitor-to-limit-the-spread-of-chemotherapy-induced-cardiomyocyte-injury-and-mitochondrial-dysfunction
#40
JOURNAL ARTICLE
Wenshe Sun, Qi Lu, Yukun Zhang, Dongming Xing
Anthracycline chemotherapeutics like doxorubicin (DOX) are widely used against various cancers but are accompanied by severe cardiotoxic effects that can lead to heart failure. Through whole transcriptome sequencing and pathological tissue analysis in a murine model, our study has revealed that DOX impairs collagen expression in the early phase, causing extracellular matrix anomalies that weaken the mechanical integrity of the heart. This results in ventricular wall thinning and dilation, exacerbating cardiac dysfunction...
March 10, 2024: Aging
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