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https://www.readbyqxmd.com/read/29302800/analysis-of-fungi-in-aerosols-dispersed-by-high-speed-pens-in-dental-clinics-from-teresina-piaui-brazil
#1
Aline Maria Alves Vilarinho Oliveira, Rômulo Maia de Alencar, Jhonatas Cley Santos Porto, Isla Rita Brito Fontenele Ramos, Iraci Salmito Noleto, Tanit Clementino Santos, Mitra Mobin
This quantitative and qualitative study aimed to evaluate the level of fungal contamination in aerosols dispersed by high rotation pens in dental clinics from Teresina, Piaui, Brazil. The data were collected during the attendance at two dental clinics. Petri dishes containing Sabouraud agar with chloramphenicol were opened for 15 min in the following places: in front of the chair, on the partitions to the right and left of the chair, and in the neighboring workbench. The plates were incubated at room temperature to allow the fungal growth and subsequent species identification...
January 4, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29290106/design-synthesis-and-antifungal-activities-of-3-acyl-thiotetronic-acid-derivatives-new-fatty-acid-synthase-inhibitors
#2
Pei Lv, Yiliang Chen, Zheng Zhao, Taozhong Shi, Xiangwei Wu, Jiaying Xue, Qing X Li, Rimao Hua
Emerging fungal phytodiseases are increasingly becoming a food security threat. Twenty-six new 3-acylthiotetronic acid derivatives were designed, synthesized, characterized, and evaluated for activities against Valsa mali, Curvularia lunata, Fusarium graminearum and Fusarium oxysporum f. sp. lycopersici. Among the 26 compounds, 6f was the most effective against V. mali, C. lunata, F. graminearum and F. oxysporum f. sp. lycopersici with median effective concentrations (EC50) of 4.1, 3.1, 3.6 and 4.1 μg/mL, respectively, while the corresponding EC50 were 0...
January 1, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29238283/involvement-of-a-polyketide-synthetase-clpks18-in-the-regulation-of-vegetative-growth-melanin-and-toxin-synthesis-and-virulence-in-curvularia-lunata
#3
Jin-Xin Gao, Jie Chen
The clpks18 gene was first cloned and identified in Curvularia lunata. It contains 6571 base pairs (bp) and an 6276 bp open reading frame encoding 2091 amino acids. The ClPKS18 deletion mutant displayed an albino phenotype, and almost lost the ability to product 5-(hydroxymethyl) furan-2-carboxylate (M5HF2C) toxin, implying that clpks18 gene in C. lunata is not only involved in 1,8-dihydroxynaphthalene melanin synthesis, but also relatively associated with M5HF2C toxin biosynthesis of the pathogen. The pathogenicity assays revealed that ΔClPKS18 was impaired in colonizing the maize leaves, which corresponds to the finding that ClPKS18 controls the production of melanin and M5HF2C in C...
December 2017: Plant Pathology Journal
https://www.readbyqxmd.com/read/29200720/extraction-of-chelerythrine-and-its-effects-on-pathogenic-fungus-spore-germination
#4
Qinghui Wei, Min Zhao, Xiaoyan Li
Background: Chemical fungicides are widely used to control crop diseases, but these chemicals have adverse effects. They destroy the ecological environment and even have toxic effects on human beings. In this context, the development of botanical pesticides is relevant. One potential botanical pesticide is chelerythrine, a main alkaloid of Chelidonium majus L., which has high antitumor, fungistasis, and antiphlogosis bioactivity. Objective: This study was designed to present an ultrasonic extraction method for chelerythrine and spore germination experiments to inhibit pathogenic fungi...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29191555/discovery-of-benzotriazole-azo-phenol-aniline-derivatives-as-antifungal-agents
#5
Min Lv, Jingchun Ma, Qin Li, Hui Xu
A series of benzotriazole-azo-phenol/aniline derivatives were prepared and evaluated for their antifungal activities against six phytopathogenic fungi such as Fusarium graminearum, Fusarium solani, Alternaria alternate, Valsa mali, Botrytis cinerea, and Curvularia lunata. Among them, compounds IIf, IIn, and IIr showed a broad-spectrum of potent antifungal activities. Especially some compounds displayed 3.5-10.8 folds more potent activities than carbendazim against A. alternata and C. lunata. Notably, compounds IIc, IIm, and IIr exhibited good protective and therapeutic effects against B...
November 16, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/29151648/antimicrobial-efficacy-of-methylated-lac-dye-an-anthraquinone-derivative
#6
Sanjay Srivastava, Arnab Roy Chowdhury, Sudarshan Maurya
A natural red dye which is produced by the tiny insects Kerria lacca while feeding on host trees is popularly known as lac dye. Lac dye is a mixture of at least five closely related pure compounds all being anthraquinone derivatives designated as laccaic acid A, B, C, D and E. Anthraquinones isolated from different natural sources and reported to have potent antimicrobial activity. The lac dye, which is also a mixture of anthraquinone derivatives, is expected to exhibit antifungal and antibacterial activity...
December 2017: Indian Journal of Microbiology
https://www.readbyqxmd.com/read/29093719/interaction-of-thp-1-monocytes-with-conidia-and-hyphae-of-different-curvularia-strains
#7
Eszter Judit Tóth, Éva Boros, Alexandra Hoffmann, Csilla Szebenyi, Mónika Homa, Gábor Nagy, Csaba Vágvölgyi, István Nagy, Tamás Papp
Interaction of the human monocytic cell line, THP-1 with clinical isolates of three Curvularia species were examined. Members of this filamentous fungal genus can cause deep mycoses emerging in both immunocompromised and immunocompetent patients. It was found that monocytes reacted only to the hyphal form of Curvularia lunata. Cells attached to the germ tubes and hyphae and production of elevated levels of interleukin (IL)-8 and IL-10 and a low level of TNF-α were measured. At the same time, monocytes failed to produce IL-6...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29091106/antimicrobial-and-enzymatic-activity-of-anemophilous-fungi-of-a-public-university-in-brazil
#8
Laureana V Sobral, Kelly N Melo, Cleciana M Souza, Sílvio F Silva, Gilvania L R Silva, Andressa L F Silva, Katharine A A Wanderley, Idjane S Oliveira, Roberta Cruz
To the fungal microbiota the UFPE and biotechnological potential enzymatic and antimicrobial production. Air conditioned environments were sampled using a passive sedimentation technique, the air I ratio and the presence of aflatoxigenic strains evaluated for ANVISA. Icelles were to determine the enzymatic activity of lipase, amylase and protease metabolic liquids to determine antimicrobial activity. Diversity was observed in all CAV environments, CFU/m3 ranged from 14 to 290 and I/E ratio from 0.1 to 1.5. The of the fungal genera were: Aspergillus (50%), Penicillium (21%), Talaromyces (14%), Curvularia and Paecilomyces (7% each)...
October 26, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29079927/characterization-and-potential-of-plant-growth-promoting-rhizobacteria-isolated-from-native-andean-crops
#9
Katty Ogata-Gutiérrez, Carolina Chumpitaz-Segovia, Jesus Lirio-Paredes, Mariella M Finetti-Sialer, Doris Zúñiga-Dávila
Bacteria isolated from soil and rhizosphere samples collected in Peru from Andean crops were tested in vitro and in vivo to determine their potential as plant growth promoters and their ability to induce systemic resistance to Alternaria alternata in tomato plants. The isolates were identified by sequencing their 16S ribosomal RNA gene. Test for phosphate solubilization, and indolacetic acid were also carried out, together with in vitro antagonism assays in dual cultures towards the plant pathogens Fusarium solani, A...
October 27, 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/29037584/fungal-biotransformation-of-diuretic-and-antihypertensive-drug-spironolactone-with-gibberella-fujikuroi-curvularia-lunata-fusarium-lini-and-aspergillus-alliaceus
#10
Amal Al-Aboudi, Belal Muneeb Kana'an, Musa Abu Zarga, Saira Bano, Atia-Tul-Wahab, Kulsoom Javed, M Iqbal Choudhary
Derivatives of spironolactone (1), a diuretic and antihypertensive drug, were synthesized by using fungal cells for the first time. Ten different fungi were screened for their ability to biotransform 1, four of which were able to produce metabolites 2-8. Gibberella fujikuroi produced canrenone (2), 1-dehydrocanrenone (3), Curvularia lunuta provided compound 2, and 7α-thio-spironolactone (4), Fusarium lini yielded compounds 2, 3, 1β-hydroxycanrenone (5), 1α-hydroxycanrenone (6), 1-dehydro-15α-hydroxycanrenone (7), and 15α-hydroxycanrenone (8), while Aspergillus alliaceus was able to produce all the seven metabolites...
October 14, 2017: Steroids
https://www.readbyqxmd.com/read/29033414/spontaneous-regression-of-allergic-bronchopulmonary-mycosis-due-to-curvularia-lunata
#11
Shingo Nasu, Shingo Satoh, Kazunori Shimizu, Osamu Matsuno, Hiroshi Morishita, Takashi Yaguchi, Kunimitsu Kawahara, Hiroto Matsuoka
Allergic bronchopulmonary mycosis (ABPM) is a pulmonary hypersensitivity disease mainly caused by Aspergillus fumigatus. The mainstay treatment for ABPM is systemic corticosteroid therapy. A 25-year-old man presented with pulmonary infiltrates. His peripheral eosinophil, total serum IgE, and serum Aspergillus-specific IgE levels were elevated. The patient tested positive in a skin test for Aspergillus. However, sputum cultures revealed a Curvularia lunata infection. We therefore diagnosed ABPM possibly caused by C...
October 16, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28991328/-nasal-phaeohyphomycosis-by-curvularia-spicifera-in-pediatric-patient-with-neutropenia-and-acute-myeloid-leukemia
#12
Constanza Bay, Tamara González, Gonzalo Munoz, Paulette Legarraga, Cecilia Vizcaya, Katia Abarca
There are very few reports of pediatric patients with infections by dematiaceous filamentous fungi. In this publication we report a case of invasive fungal infection of the nasal septum by Curvularia spicifera in a pediatric patient with acute myeloid leukemia. The patient presented with a painful scabby wound in the nasal vestibule. Culture and universal PCR were consistent with Curvularia spicifera. Early management with surgical debridement and bi-associated antifungal therapy achieved complete resolution of the lesions, with no evidence of dissemination and relapses...
June 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28982951/in-vitro-synergy-of-natamycin-and-voriconazole-against-clinical-isolates-of-fusarium-candida-aspergillus-and-curvularia-spp
#13
Swatishree Sradhanjali, Bandana Yein, Savitri Sharma, Sujata Das
AIM: To determine the minimum inhibitory concentrations (MICs) of voriconazole and natamycin, alone and in combination, against the clinical isolates of Fungus and to evaluate the synergy between the drugs in an experimental in vitro study. METHODS: In an experimental in vitro study, clinical isolates of Fusarium, Aspergillus, Candida and Curvularia spp were maintained on Sabouraud Dextrose Agar and used for the study. The MICs of natamycin and voriconazole, used alone and in combination, were evaluated by checkerboard microdilution technique based on the standard protocol proposed by the Clinical Laboratory Standards Institute...
January 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28930276/essential-oil-of-cymbopogon-citratus-on-the-control-of-the-curvularia-leaf-spot-disease-on-maize
#14
Dalmarcia de Sousa Carlos Mourão, Talita Ferreira de Souza Pereira, Danival José de Souza, Aloísio Freitas Chagas Júnior, Mateus Sunti Dalcin, Ronice Alves Veloso, Evelynne Urzêdo Leão, Gil Rodrigues Dos Santos
The Curvularia Leaf Spot is becoming more common due to the culture expansion and the low resistance of the cultivated genotypes in tropical regions. Thus, the objective was to evaluate the fungitoxicity of the essential oil of Cymbopogon citratus upon the phytopathogen Curvularia lunata, causative agent of the Curvularia Leaf Spot. There was realized pathogenicity tests of C. lunata in maize plants, phytotoxicity of the essential oil of C. citratus and gas chromatography attached, germination tests of the conidia, and of in vitro inhibition of C...
August 20, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28867950/extracellular-alkaline-lipase-from-a-novel-fungus%C3%A2-curvularia-sp-dhe-5-optimisation-of-physicochemical-parameters-partial-purification-and-characterisation
#15
Dina Helmy El-Ghonemy, Mamdouh S El-Gamal, Amir Elsayed Tantawy, Thanaa Hamed Ali
Thirty isolated fungal strains were screened for lipase production using Phenol Red plates, containing tributyrin as lipidic substrate, and a novel fungus identified genetically as Curvularia sp. DHE 5 was found as the most prominent strain. Various agro-industrial substrates were evaluated as inert supports for lipase production in solid-state fermentation. The highest yield of lipase ((83.4±2.2) U/g on dry mass basis) was reported with wheat bran medium after seven days of fermentation at pH=7.0, temperature of 30 °C, 70% moisture content, inoculum size of 1...
June 2017: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/28861773/biodegradation-of-pulp-and-paper-mill-effluent-by-co-culturing-ascomycetous-fungi-in-repeated-batch-process
#16
Deepika Rajwar, Rashmi Paliwal, J P N Rai
The competence of novel fungal consortium, consisting of Nigrospora sp. LDF00204 (accession no. KP732542) and Curvularia lunata LDF21 (accession no. KU664593), was investigated for the treatment of pulp and paper mill effluent. Fungal consortium exhibited enhanced biomass production under optimized medium conditions, i.e., glucose as carbon (C), sodium nitrate as nitrogen (N), C/N 1.5:0.5, pH 5, temperature 30 °C, and agitation 140 rpm, and significantly reduced biochemical oxygen demand (85.6%), chemical oxygen demand (80%), color (82...
August 31, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28861045/exploring-the-potentials-of-lysinibacillus-sphaericus-za9-for-plant-growth-promotion-and-biocontrol-activities-against-phytopathogenic-fungi
#17
Zakira Naureen, Najeeb Ur Rehman, Hidayat Hussain, Javid Hussain, Syed A Gilani, Saif K Al Housni, Fazal Mabood, Abdul L Khan, Saima Farooq, Ghulam Abbas, Ahmed A Harrasi
There is an ongoing hunt for biologically active compounds that can combat phytopathogenic fungi and improve plant growth without causing any hazards to the environment. Consequently the present study aims at deciphering the plant growth promotion and antifungal capability of Lysinibacillus sphaericus ZA9. The bacterium was previously isolated and identified in our laboratory from maize rhizosphere using 16S rRNA gene sequencing. The test bacterium L. sphaericus ZA9 was found to produce high quantity of IAA (697 μg/ mL); siderophores (195...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28851884/cu-chitosan-nanoparticle-boost-defense-responses-and-plant-growth-in-maize-zea-mays-l
#18
Ram Chandra Choudhary, R V Kumaraswamy, Sarita Kumari, S S Sharma, Ajay Pal, Ramesh Raliya, Pratim Biswas, Vinod Saharan
In agriculture, search for biopolymer derived materials are in high demand to replace the synthetic agrochemicals. In the present investigation, the efficacy of Cu-chitosan nanoparticles (NPs) to boost defense responses against Curvularia leaf spot (CLS) disease of maize and plant growth promotry activity were evaluated. Cu-chitosan NPs treated plants showed significant defense response through higher activities of antioxidant (superoxide dismutase and peroxidase) and defense enzymes (polyphenol oxidase and phenylalanine ammonia-lyase)...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28847019/metabolomic-guided-isolation-of-bioactive-natural-products-from-curvularia-sp-an-endophytic-fungus-of-terminalia-laxiflora
#19
Ahmed F Tawfike, Grainne Abbott, Louise Young, RuAngelie Edrada-Ebel
Endophytic fungi associated with medicinal plants are a potential source of novel chemistry and biology. Metabolomic tools were successfully employed to compare the metabolite fingerprints of solid and liquid culture extracts of endophyte Curvularia sp. isolated from the leaves of Terminalia laxiflora. Natural product databases were used to dereplicate metabolites in order to determine known compounds and the presence of new natural products. Multivariate analysis highlighted the putative metabolites responsible for the bioactivity of the fungal extract and its fractions on NF-κB and the myelogenous leukemia cell line K562...
August 28, 2017: Planta Medica
https://www.readbyqxmd.com/read/28833313/ecology-and-identification-of-environmental-fungi-and-metabolic-processes-involved-in-the-biodeterioration-of-brazilian-soapstone-historical-monuments
#20
D Boniek, I de Castro Mendes, C A O Paiva, U G de Paula Lana, A F B Dos Santos, M A de Resende Stoianoff
This study aimed to evaluate the action of organic acids produced by the fungal population associated with the biodeterioration process of the Twelve Prophets of Aleijadinho, a set of soapstone sculptures in Congonhas, state of Minas Gerais, Brazil. For this, samples of fungi were obtained from the surface of each of the 12 outdoor stone sculptures that comprise the set of Prophets. The identification of the colonizing filamentous fungi was performed by classical microbiology and molecular methods. Some species of filamentous fungi-dependent cultivation were detected, and the presence of species Aspergillus versicolor, Curvularia lunata, Epicoccum nigrum, Penicillium citrinum and Pseudocercospora norchiensis indicated a connection with the excretion of organic acids...
August 20, 2017: Letters in Applied Microbiology
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