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Allergic fungal sinusitis

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https://www.readbyqxmd.com/read/27601608/are-allergic-fungal-rhinosinusitis-and-allergic-bronchopulmonary-aspergillosis-lifelong-conditions
#1
Ritesh Agarwal, Sandeep Bansal, Arunaloke Chakrabarti
Aspergillus fumigatus can cause several allergic disorders including Aspergillus-sensitized asthma, allergic bronchopulmonary aspergillosis (ABPA), and allergic fungal rhinosinusitis (AFRS). ABPA is an immunological pulmonary disorder caused by allergic reactions mounted against antigens of A. fumigatus colonizing the airways of patients with asthma (and cystic fibrosis). Allergic bronchopulmonary mycosis is an allergic fungal airway disease caused by thermotolerant fungi other than A. fumigatus On the other hand, AFRS is a type of chronic rhinosinusitis that is also a result of hypersensitivity reactions to the presence of fungi that become resident in the sinuses...
September 6, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27577717/predicting-revision-sinus-surgery-in-allergic-fungal-and-eosinophilic-mucin-chronic-rhinosinusitis
#2
Ramzi T Younis, Jamal Ahmed
BACKGROUND: Chronic rhinosinusitis consists of several disease processes. Eosinophilic mucin is found in the subtypes of allergic fungal sinusitis (AFS) and eosinophilic mucin chronic rhinosinusitis (EMCRS). These entities frequently require surgical intervention and have high recurrence rates. OBJECTIVE: We aimed to determine factors in patients with AFS and EMCRS that may be associated with a higher rate of revision surgeries. Our hypothesis is that patients who have polyps, high Lund-Mackay score (LMS), and fungus may have higher revision rates...
August 31, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27560920/-cross-reactivity-in-allergic-fungal-sinusitis-case-report
#3
Sandra Nora González-Díaz, Alfredo Arias-Cruz, Dulce María Rivero-Arias, Alma Belén Partida-Ortega, Bárbara Elizondo-Villarreal, Jesús Arturo Ibarra-Chávez, Lissette Ramos-Valencia, Olga Patricia Monge-Ortega, Carlos Macouzet-Sánchez, María Rocío Salinas-Díaz
BACKGROUND: The presence of allergic mucin in allergic fungal sinusitis (AFS) is a manifestation that identifies it as a hypersensitivity process. AFS has a phenomenon of cross-reactivity to IgE-bound proteins having at least two shared epitopes. CLINICAL REPORT: A 13-year-old male with nasal obstructive symptoms of three years of evolution. An obstructive mass was identified in the sinuses through physical examination and CT. In endoscopic surgery, the left nostril polyp was identified with the macroscopic appearance of allergic mucin; the polyp was resected...
July 2016: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/27466842/allergic-fungal-rhinosinusitis-the-latest-in-diagnosis-and-management
#4
Patricia A Loftus, Sarah K Wise
Allergic fungal rhinosinusitis (AFRS) is the most common form of fungal sinusitis in the United States. Its pathophysiological basis is associated with a predisposed person's type I IgE-mediated allergic response to inhaled mold spores that are ubiquitous in the environment. AFRS is a well-recognized type of chronic, recurrent, and non-invasive hypertrophic sinus disease that affects immunocompetent hosts, most commonly young African American males. There are 5 main criteria used for the diagnosis of AFRS, one being the presence of nasal polyposis...
2016: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27466841/differential-diagnosis-of-chronic-rhinosinusitis-with-nasal-polyps
#5
Nyall R London, Douglas D Reh
Nasal polyps are semi-translucent mucosal outgrowths of the paranasal sinuses which typically arise in the setting of chronic rhinosinusitis (CRS). Nasal polyps are also associated with asthma, aspirin sensitivity, cystic fibrosis and allergic fungal rhinosinusitis (AFS). The majority of nasal polyps are bilateral and characterized by tissue edema and eosinophil infiltration. Patients with nasal polyps often present with complaints including nasal obstruction, congestion, rhinorrhea or altered sense of smell...
2016: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27456592/complications-of-sinusitis
#6
Tara F Carr
BACKGROUND: Sinusitis is a common disorder associated with significant patient symptomatology that adversely affects quality of life. Sinusitis can cause further morbidity and mortality through its impact on comorbid disorders, progression of inflammation, and extension of infection. OBJECTIVE: This review highlights common complications of acute bacterial rhinosinusitis (ABRS) and chronic rhinosinusitis (CRS). RESULTS: ABRS is complicated by orbital infections, such as pre- or postseptal cellulitis, and by intracranial infections, including abscesses of the epidural and subdural spaces...
July 2016: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/27403401/sinonasal-fungal-infections-and-complications-a-pictorial-review
#7
Jose Gavito-Higuera, Carola Birgit Mullins, Luis Ramos-Duran, Hugo Sandoval, Nassim Akle, Ramon Figueroa
Fungal infections of the nose and paranasal sinuses can be categorized into invasive and non-invasive forms. The clinical presentation and course of the disease is primarily determined by the immune status of the host and can range from harmless or subtle presentations to life threatening complications. Invasive fungal infections are categorized into acute, chronic or chronic granulomatous entities. Immunocompromised patients with poorly controlled diabetes mellitus, HIV and patients receiving chemotherapy or chronic oral corticosteroids are mostly affected...
2016: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/27393774/allergic-fungal-rhinosinusitis
#8
Alice E W Hoyt, Larry Borish, José Gurrola, Spencer Payne
This article reviews the history of allergic fungal rhinosinusitis and the clinical, pathologic, and radiographic criteria necessary to establish its diagnosis and differentiate this disease from other types of chronic rhinosinusitis. Allergic fungal rhinosinusitis is a noninvasive fungal form of sinus inflammation characterized by an often times unilateral, expansile process in which the typical allergic "peanut-butter-like" mucin contributes to the formation of nasal polyps, hyposmia/anosmia, and structural changes of the face...
July 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27335058/contribution-of-molecular-tools-for-the-diagnosis-and-epidemiology-of-fungal-chronic-rhinosinusitis
#9
Pauline Comacle, Sorya Belaz, Franck Jegoux, Christophe Ruaux, François Le Gall, Jean-Pierre Gangneux, Florence Robert-Gangneux
Chronic rhinosinusitis (CRS) rank second at chronic inflammatory diseases in industrialized countries and are an important public health concern. Diagnosis relies on a set of arguments including clinical signs, imaging, histopathologic and mycological analyses of sinus specimens, collected during nasal endoscopy. The sensitivity of fungal cultures is reported to be poor, even when direct examination is positive, thus the epidemiology of fungal chronic sinusitis is ill-known. This study evaluated the sensitivity of molecular diagnosis in 70 consecutive samples (61 patients with CRS) analysed at the University Hospital of Rennes during a 3-year period...
November 1, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27280099/smell-decline-as-a-good-predictor-of-sinonasal-polyposis-recurrence-after-endoscopic-surgery
#10
Mahdi Bakhshaee, Mohammad Reza Sharifian, Amir Hossain Ghazizadeh, Kianoosh Nahid, Karim Jalaeian Samani
INTRODUCTION: To evaluate the most sensitive symptom to predict early recurrence of nasal polyposis. Prospective longitudinal cohort study. Tertiary university referral center with accredited otorhinolaryngology residency programs. MATERIALS AND METHODS: In this prospective study, we evaluated 62 patients with diffuse nasal polyposis. All patients underwent functional endoscopic sinus surgery. The author-devised questionnaire relating to the four major symptoms of chronic rhinosinusitis were answered by patients at the pre-operative visit and at 1, 3, 6, 12, and 24 months after surgery...
March 2016: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27172454/a-case-control-study-of-medical-psychological-and-socio-economic-factors-influencing-the-severity-of-chronic-rhinosinusitis
#11
Carl Philpott, Sally Erskine, Claire Hopkins, Emma Coombes, Naveed Kara, Vishnu Sunkareneni, Shahram Anari, Mahmoud Salam, Amir Farboud, Allan Clark
BACKGROUND: Chronic rhinosinusitis (CRS) is a common and debilitating disorder. Little is known about the epidemiology of this disease. The aims of the study were to identify differences in socio-economic variables and quality of life between patients with chronic rhinosinusitis and healthy controls, to identify any significant associations between CRS and other medical co-morbidities, psychiatric disease or environmental exposure and to explore the experience of CRS from the perspective of CRS sufferers...
June 2016: Rhinology
https://www.readbyqxmd.com/read/27171958/chronic-rhinosinusitis-with-massive-polyposis-causing-proptosis-requiring-craniofacial-resection
#12
Mazda K Turel, Christopher J Chin, Allan D Vescan, Fred Gentili
Chronic rhinosinusitis (CRS) is a common health problem in the Western world. CRS is classified as CRS with (CRSwNP) and without (CRSsNP) nasal polyps. A less common third type is allergic fungal sinusitis, which often presents with polyps and, not infrequently, skull base erosion. Most patients are successfully managed with maximal medical therapy or endoscopic approaches. There are currently no reports of CRSwNPs resulting in fibro-osseous thickening and proptosis in the English literature. As such, the authors report a case of a 33-year-old man who underwent a craniofacial resection with drilling of the hyperostosed bone, which led to resolution of the proptosis and nasal symptoms...
June 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27153455/evaluation-of-malassezia-and-common-fungal-pathogens-in-subtypes-of-chronic-rhinosinusitis
#13
Jonathan T Gelber, Emily K Cope, Andrew N Goldberg, Steven D Pletcher
BACKGROUND: Fungal hypersensitivity and fungal microbiome dysbiosis are possible etiologies of chronic rhinosinusitis. The sinus fungal microbiome is not well characterized; novel sinus-associated fungi, including Malassezia, have only recently been described. The goals for this study were to verify Malassezia as a dominant component of the sinus microbiome, to speciate sinus Malassezia, and to compare select fungal species in chronic rhinosinusitis (CRS) subtypes with known fungal association to chronic rhinosinusitis with polyps (CRSwNP) and healthy controls...
September 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27126721/allergic-bronchopulmonary-aspergillosis-a-perplexing-clinical-entity
#14
REVIEW
Ashok Shah, Chandramani Panjabi
In susceptible individuals, inhalation of Aspergillus spores can affect the respiratory tract in many ways. These spores get trapped in the viscid sputum of asthmatic subjects which triggers a cascade of inflammatory reactions that can result in Aspergillus-induced asthma, allergic bronchopulmonary aspergillosis (ABPA), and allergic Aspergillus sinusitis (AAS). An immunologically mediated disease, ABPA, occurs predominantly in patients with asthma and cystic fibrosis (CF). A set of criteria, which is still evolving, is required for diagnosis...
July 2016: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/27101680/-clinical-analysis-of-fungal-rhino-sinusitis-in-189-cases
#15
Lin Lin, Ni Zhou, Zisong Chen
OBJECTIVE: To investigate the clinical features of fungal rhino-sinusitis. METHOD: Clinical data of 189 patients suffering from fungal rhino-sinusitis treated by functional endoscopic sinus surgery was analyzed retrospectively. The analyzed data included clinical type, age of onset, predilectionsite, reason, and surgical outcome. RESULT: Among the 189 patients with fungal rhino-sinusitis,181 cases were fungal ball,6 cases were allergic fungal rhino-sinusitis, 1 case was acute invasive fungnal rhino-sinusitis, 1 case was chronic invasive fungnal rhino-sinusitis...
December 2015: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/27055989/possible-allergic-fungal-sinusitis
#16
REVIEW
Richard D deShazo, Scott Stringer, Leigh Baldwin Skipworth
No abstract text is available yet for this article.
April 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/26998375/hyperprolactinemia-secondary-to-allergic-fungal-sinusitis-compressing-the-pituitary-gland
#17
Nikita Chapurin, Cynthia Wang, David M Steinberg, David W Jang
Objective. We aim to describe the first case in the literature of allergic fungal sinusitis (AFS) presenting with hyperprolactinemia due to compression of the pituitary gland. Case Presentation. A 37-year-old female presented with bilateral galactorrhea and occipital headaches of several weeks. Workup revealed elevated prolactin of 94.4, negative pregnancy test, and normal thyroid function. MRI and CT demonstrated a 5.0 × 2.7 × 2.5 cm heterogeneous expansile mass in the right sphenoid sinus with no pituitary adenoma as originally suspected...
2016: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/26980383/quality-of-life-outcomes-after-sinus-surgery-in-allergic-fungal-rhinosinusitis-versus-nonfungal-chronic-rhinosinusitis
#18
Liam Masterson, Francesco M Egro, Jessica Bewick, Sally E Erskine, Alan Clark, Amin R Javer, Carl M Philpott
BACKGROUND: Given the differences in pathophysiology between allergic fungal rhinosinusitis (AFRS) and other chronic rhinosinusitis (CRS) subgroups, it remains unclear about whether these patients respond differently to a combination of surgical and medical treatments. OBJECTIVE: To evaluate differences in quality-of-life (QoL) outcomes for a cohort of patients who underwent endoscopic sinus surgery (ESS) for CRS. METHODS: This retrospective review included patients with CRS who underwent ESS between 2010 and 2013...
March 2016: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/26834076/effectiveness-of-leukotriene-receptor-antagonism-in-the-postoperative-management-of-chronic-rhinosinusitis
#19
Joshua C Yelverton, Thomas W Holmes, Christopher M Johnson, Camilo Reyes Gelves, Stilianos E Kountakis
BACKGROUND: Montelukast is used in the treatment of allergic rhinitis and asthma. It has been used as adjuvant therapy in patients with chronic rhinosinusitis (CRS), but its effectiveness has not been evaluated. This study evaluates the efficacy of adjuvant leukotriene receptor antagonism in CRS and subtypes. METHODS: Retrospective review of collected data at a tertiary-referral institution. We identified all patients who were prescribed montelukast postoperatively and had a lapse in therapy for at least 1 month (n = 50), so that the patients themselves serve as their own control group...
March 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/26768883/gynecomastia-and-hyperprolactinemia-secondary-to-advanced-allergic-fungal-rhinosinusitis-in-a-pediatric-patient
#20
Joshua Y Menendez, Bradford A Woodworth, James M Johnston
Hyperprolactinemia is a rare entity in the pediatric population. The most common causes of hyperprolactinemia include drug use, hypothyroidism and renal insufficiency, though rarely a pituitary or sellar mass is discovered. We present an immunocompetent pediatric patient who presented with gynecomastia and was found to have hyperprolactinemia. Imaging showed a sphenoid mass and referral was made for a pituitary tumor. The mass was not a pituitary tumor and he was formally diagnosed with allergic fungal sinusitis and treated surgically...
2016: Turkish Neurosurgery
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