keyword
MENU ▼
Read by QxMD icon Read
search

eyes tumours

keyword
https://www.readbyqxmd.com/read/29150462/comprehensive-analysis-of-vitreous-specimens-for-uveitis-classification-a-prospective-multicentre-observational-study
#1
Kazuichi Maruyama, Tohru Inaba, Sunao Sugita, Ryo Ichinohasama, Kenji Nagata, Shigeru Kinoshita, Manabu Mochizuki, Toru Nakazawa
PURPOSE: To determine the clinical relevance of vitreous biomarkers in patients with uveitis. DESIGN: Multicentre, prospective, observational study. SETTING: Uveitis outpatient clinics of two academic medical centres in Japan. PATIENT POPULATION: This study included 234 eyes of 191 patients with various uveitis aetiologies: definitive sarcoidosis (61 eyes of 46 patients), suspected sarcoidosis (60 eyes of 45 patients), intraocular tumour (34 eyes of 27 patients), viral infection (20 eyes of 18 patients), non-sarcoidosis (16 eyes of 16 patients) and unknown aetiology (43 eyes of 39 patients)...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29128996/e-derma-a-novel-wireless-dermatoscopy-system
#2
Bogdan Dugonik, A Dugonik, D Horvat, B Žalik, D Špelič
Cutaneous Melanoma (CM) is a malignant tumour, and is one of the most rapidly growing cancers. Discovering a melanoma in the early stages of the disease is extremely difficult and, as such, only an invasive disease stage can be identified easily with the naked eye. Dermatoscopy is a diagnostic method intended to maximise early detection of CM performed by the dermatoscopy system. To address the limitations of existing systems a novel, wireless digital dermatoscopy system is presented for providing high-resolution images...
November 11, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/29119030/latanoprost-induced-iris-pigment-epithelial-and-ciliary-body-cyst-formation-in-hypermetropic-eyes
#3
Abhijit Anand Mohite, Rangarajan V Prabhu, Thomas Ressiniotis
Purpose: Latanoprost has become one of the most widely prescribed topical antihypertensive medications in recent years. Yet there have been few reports of secondary iris pigment epithelial (IPE) and ciliary body (CB) cyst formation to date and none, to our knowledge, reported in eyes predisposed to primary angle closure. Methods: We report the first documented case of bilateral IPE and CB cysts in a hypermetropic patient with prior laser peripheral iridotomies (LPIs) as a rare, delayed side effect of topical Latanoprost treatment...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/29109715/specific-detection-of-serum-antibodies-against-bkpyv-a-small-dna-tumour-virus-in-patients-affected-by-choroidal-nevi
#4
Silvia Pietrobon, Ilaria Bononi, Francesca Lotito, Paolo Perri, Sara Violanti, Elisa Mazzoni, Fernanda Martini, Mauro G Tognon
Ocular or choroidal nevus (CN) is a rare benign neoplastic lesion of the eye. The cause of CN onset/progression, which arises from the transformation of ocular melanocytes, is not known. A fraction of CN patients may develop uveal melanoma. The objective of this study was to investigate the association between CN and BK polyomavirus (BKPyV), a small DNA tumor virus. Serum IgG antibodies which react with BKPyV antigens were analyzed. An indirect E.L.I.S.A. using synthetic peptides that mimic BKPyV antigens was employed...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29089812/papillary-thyroid-carcinoma-in-a-boy-with-familial-tuberous-sclerosis-complex-attributable-to-a-tsc2-deletion-a-case-report
#5
M Flader, P Kurzawa, J Maldyk, J Sygut, J Harasymczuk, A Kropinska, D Handkiewicz-Junak, B Jarzab, K Kotulska, M Niedziela
Tuberous sclerosis complex (tsc), a phacomatosis, is a rare genetic disease (autosomal dominant; incidence: 1 in 6,800-17,300) associated with mutations in the TSC1 and TSC2 genes, 70% of which are sporadic. The disease causes benign tumours in the brain, kidneys, heart, lungs, skin, and eyes; thyroid lesions are extremely rare. A 13-year-old euthyroid boy with a hereditary form of tsc (del 4730G in TSC2, also seen in 2 sisters and the father) was admitted to hospital with a thyroid nodule. Physical examination revealed a nodular left lobe with increased consistency...
October 2017: Current Oncology
https://www.readbyqxmd.com/read/29089355/assessment-of-retinoblastoma-rna-reflux-after-intravitreal-injection-of-melphalan
#6
Ursula Winter, Michael Nicolas, Mariana Sgroi, Claudia Sampor, Ana Torbidoni, Adriana Fandiño, Guillermo L Chantada, Francis L Munier, Paula Schaiquevich
BACKGROUND: Intravitreal injection of chemotherapy in retinoblastoma eyes with vitreous seeds may lead to a risk of extraocular tumour dissemination that has not been assessed so far. AIMS: To develop a sensitive and clinically feasible technique to assess for potential retinoblastoma cell reflux after intravitreal injection of melphalan. METHODS: Filter papers were cut in 6 mm diameter circles and sterilised before use. Eyes with retinoblastoma vitreous seeds (group D, International Classification) received weekly intravitreal melphalan injections (20 µg or 30 µg/dose) followed by cryotherapy as part of local treatment...
October 31, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29062764/gastrodin-protects-retinal-ganglion-cells-through-inhibiting-microglial-mediated-neuroinflammation-in-an-acute-ocular-hypertension-model
#7
Jia-Wei Wang, Yao-Ming Liu, Xiao-Fei Zhao, Han Zhang
AIM: To investigate the neuroprotective effect of gastrodin on retinal ganglion cells (RGCs) in an acute ocular hypertension (AOH) rat model and to identify its possible mechanism. METHODS: AOH rat model was performed in a randomly selected eye by anterior chamber perfusion and either received an intraperitoneal injection with various concentrations of gastrodin or normal saline. After 2wk, the rats were sacrificed. FluoroGold was used to label survival RGCs. Immunostaining with anti-Iba1 in the retinal flat mounts to calculate the microglia density in the ganglion cell layer (GCL)...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29043448/-retinoblastoma-and-retinocytoma-retinoma
#8
REVIEW
K A Metz, D Westerwick, F Driever, K W Schmid, C H D Le Guin
Retinoblastomas are extremely rare withabout half of the cases being hereditary eye neoplasms in young children. They show highly proliferative, CRX-positive undifferentiated tumour cells (occasionally forming rosettes). Staging is performed according to the pTNM classification and the International Retinoblastoma Staging System (IRSS). The diagnostic basis for systemic administration of chemotherapy and/or radiation is postlaminar optic nerve invasion, massive choroidal tumour infiltration, scleral invasion or even extraocular invasion...
November 2017: Der Pathologe
https://www.readbyqxmd.com/read/29022961/orbital-teratoma-a-rare-congenital-tumour
#9
Simanta Khadka, Gulshan Bahadur Shrestha, Pragati Gautam, Jyoti Baba Shrestha
BACKGROUND: Orbital teratomas are congenital, unilateral germ cell tumors, which are present at birth with moderate to massive proptosis. The rare tumour has to be managed individually and is at times difficult. CASE: A female child in her 2nd day of life was brought to our department with complains of forward bulging of the left eye which was noticed since the time of her birth. OBSERVATION: Examination and investigations revealed a mass with scattered foci of calcification...
January 2017: Nepalese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29018015/chronic-red-eye-a-masquerade-of-advanced-neoplastic-disease
#10
Joana Providência, Filipa Ponces, Guilherme Castela, Joaquim Murta
A 42-year-old woman presented with chronic history of left red eye for more than 12 months, treated with difference topical medication but without response. Ocular external examination demonstrated a firm palpable mass in the medial portion of the lower eyelid and slit-lamp evaluation of the lesion showed an ulcerated conjunctival nodule, keratin secretor. CT of the orbits revealed left-sided orbital mass located anteriorly, inferiorly and medially in the orbit, adjacent to the globe and orbit walls. Incisional biopsy of the lesion was consistent with invasive squamous cell carcinoma of the conjunctiva...
October 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28960216/clinical-evaluation-of-a-paper-chart-for-predicting-ruthenium-plaque-placement-in-relation-to-choroidal-melanoma
#11
I Rospond-Kubiak, J Kociecki, B Damato
PurposeTo determine the accuracy of estimated tumour location and required plaque position using fundus diagrams, and to evaluate their applicability in daily clinical practice.Patients and methodsBetween September 2013 and March 2016, all patients treated with ruthenium plaque brachytherapy for choroidal melanoma at the Department of Ophthalmology in Poznań underwent pretreatment planning with the use of printed or electronic fundus diagrams www.oculonco.comThe estimated distances were then verified intraoperatively...
September 29, 2017: Eye
https://www.readbyqxmd.com/read/28955092/role-of-5-ala-in-improving-extent-of-tumour-resection-in-patients-with-glioblastoma-multiforme
#12
Muhammad Waqas, Inamullah Khan, Muhammad Shahzad Shamim
Goal of surgery for patients with Glioblastoma Multiforme (GBM) is gross total resection with no new neurological deficits. Surgical resection is often restricted due the difficulty in differentiating the tumour from surrounding normal brain using either naked eye, or standard intra-operative white light microscopy. GBM uptakes orally administered 5-ALA becomes fluorescent when viewed by a special light, and this property has been used to improve intra-operative tumour identification. This technique should therefore allow better extent of tumour resection...
October 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28937145/immunoreduction-of-ocular-surface-tumours-with-intralesional-interferon-alpha-2a
#13
S E Kim, S M Salvi
PurposeTo share our initial experience in the use of intralesional interferon alpha-2a at primary presentation in ocular surface tumours as a method of immunoreduction prior to definitive surgical management.MethodsCase series of patients referred to Sheffield Ocular Oncology Service with rapidly growing ocular surface tumours, treated with intralesional interferon alpha-2a at first presentation prior to definitive surgical management.ResultsAll three patients, two with conjunctival melanoma and one with ocular surface squamous neoplasia (OSSN) demonstrated immunoreduction of tumour without any adverse side effects...
September 22, 2017: Eye
https://www.readbyqxmd.com/read/28891338/synthesis-and-biological-evaluation-of-benzenesulphonamide-bearing-1-4-5-trisubstituted-1-2-3-triazoles-possessing-human-carbonic-anhydrase-i-ii-iv-and-ix-inhibitory-activity
#14
Rajiv Kumar, Vikas Sharma, Silvia Bua, Claudiu T Supuran, Pawan K Sharma
A library of benzenesulphonamides incorporating 1,2,3-triazole rings functionalised with ester, carboxylic acid, carboxamide, carboxyhydrazide, and hydroxymethyl moieties were synthesised. The carbonic anhydrase (CAs, EC 4.2.1.1) inhibitory activity of the new compounds was assessed against four human (h) isoforms, hCA I, hCA II, hCA IV, and hCA IX. Among them, hCA II and IV are anti-glaucoma drug targets, being involved in aqueous humour secretion within the eye. hCA I was inhibited with Ki's ranging between 8...
December 2017: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/28886932/human-immunodeficiency-virus-associated-giant-conjunctival-kaposi-s-sarcoma-complete-remission-with-antiretroviral-therapy-and-systemic-chemotherapy
#15
Y W Eduardo-Sánchez, D Fernández-Agrafojo
CASE REPORT: A 35-year-old male patient with a large unilateral haemorrhagic conjunctival tumour lesion and another contralateral haemorrhagic conjunctival flat lesion associated with violaceous cutaneous macules on the extremities and angiomatous lesions in the upper gastrointestinal tract as initial clinical manifestation of HIV-related immunodeficiency. Cutaneous, gastric mucosal and conjunctival biopsy was consistent with Kaposi's sarcoma with complete remission after highly active antiretroviral therapy and systemic chemotherapy...
September 5, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28851495/intensity-modulated-radiotherapy-in-head-and-neck-cancer-an-update-for-oral-and-maxillofacial-surgeons
#16
REVIEW
P A Brennan, K L Bradley, M Brands
Intensity-modulated radiation therapy (IMRT), a relatively new method of delivering radiotherapy, can precisely target a point within a specific tumour and reduce the dose to nearby anatomical structures. This is particularly important in the head and neck where radiotherapy can easily and irreparably damage the salivary glands, spinal cord, and eyes, and where, with increasingly better outcomes and survival, late complications of conventional radiotherapy (including osteoradionecrosis of the cervical spine) can be difficult to manage...
October 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28844050/intravitreal-topotecan-in-the-management-of-refractory-and-recurrent-vitreous-seeds-in-retinoblastoma
#17
Raksha Rao, Santosh G Honavar, Vishal Sharma, Vijay Anand P Reddy
BACKGROUND/AIM: To evaluate the efficacy of intravitreal topotecan for refractory or recurrent vitreous seeds in retinoblastoma. METHODS: Intravitreal injection of topotecan hydrochloride (30 µg/0.15 mL) was provided every 3 weeks by the safety enhanced technique. RESULTS: The study included 17 consecutive patients with retinoblastoma with refractory or recurrent vitreous seeds. Five eyes (29%) belonged to International Classification of Retinoblastoma group C and 12 eyes (71%) belonged to group D...
August 26, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28835829/conjunctival-leiomyosarcoma-a-fairly-common-tumour-in-an-uncommon-site
#18
Reubina Wadee
BACKGROUND: Leiomyosarcomas of soft tissue are malignant tumours that are not infrequently encountered in clinical medicine and histopathology. Such sarcomas of the eye are, however, a rare occurrence. PURPOSE: Herein, the histopathological features of a case of conjunctival leiomyosarcoma are described. A 38-year-old HIV-positive male, who was otherwise fit and healthy, presented with redness of his right eye and a mass of the conjunctiva. Clinically, he did not have any soft-tissue masses elsewhere in the body...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28834323/the-first-description-of-the-complete-natural-history-of-uveal-melanoma-by-two-scottish-surgeons-allan-burns-and-james-wardrop
#19
Tero T Kivelä
James Wardrop (1782-1869), a young Scottish surgeon and an early ophthalmologist in Edinburgh, is credited for describing in 1809 retinoblastoma as an entity in his treatise 'Observations on Fungus Haematodes or Soft Cancer'. His treatise also reveals that Allan Burns (1781-1813), another young Scottish surgeon and anatomist, had invited Wardrop to assist in enucleating an eye from a 41-year-old Glasgow woman who, in retrospect, had a uveal melanoma. Her eye had become blind 4 months after symptoms of exudative retinal detachment had appeared, and it had become painful after a further 2-4 months...
August 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28812406/types-of-orbital-osteoma-a-descriptive-analysis
#20
Tayyab Afghani, Hassan Mansoor
AIMS: This study describes different types of orbital osteoma based on clinical per-operative morphology and radiological findings to facilitate communication between ophthalmologists and surgical management for a better patient outcome. MATERIALS AND METHODS: The study was conducted in the Orbit and Oculoplastics Department of Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan, from July 1, 2001 to June 30, 2014. A retrospective analysis of 520 diagnosed orbital tumours who presented to us was carried out and the prevalence of orbital osteoma was determined...
August 16, 2017: Orbit
keyword
keyword
98373
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"