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intrauterine adhesions

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https://www.readbyqxmd.com/read/28034657/failure-of-physiologic-transformation-of-spiral-arteries-endothelial-and-trophoblast-cell-activation-and-acute-atherosis-in-the-basal-plate-of-the-placenta
#1
Carlos A Labarrere, Hector L Dicarlo, Elaine Bammerlin, James W Hardin, Yeon M Kim, Piya Chaemsaithong, David M Haas, Ghassan S Kassab, Roberto Romero
BACKGROUND: Failure of physiologic transformation of spiral arteries has been reported in preeclampsia, fetal growth restriction, fetal death, and spontaneous preterm labor with intact or ruptured membranes. Spiral arteries with failure of physiologic transformation are prone to develop atherosclerotic-like lesions of atherosis. There are striking parallels between preeclampsia and atherosclerotic disease, and between lesions of atherosis and atherosclerosis. Endothelial activation, identified by intercellular adhesion molecule-1 (ICAM-1) expression, is present in atherosclerotic-like lesions of heart transplantation, and is considered a manifestation of rejection...
December 26, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28034338/bioengineering-strategies-to-treat-female-infertility
#2
Che-Ying Kuo, Hannah B Baker, Melissa H Fries, James J Yoo, Peter Cw Kim, John P Fisher
Bioengineering strategies have demonstrated enormous potential to treat female infertility as a result of chemotherapy, uterine injuries, fallopian tube occlusion, massive intrauterine adhesions, congenital uterine malformations and hysterectomy. These strategies can be classified into two broad categories: 1) Transplantation of fresh or cryopreserved organs into the host; and 2) tissue engineering approaches that utilize a combination of cells, growth factors and biomaterials that leverages the body's inherent ability to regenerate/repair reproductive organs...
December 30, 2016: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/27998009/endometriosis-associated-infertility-aspects-of-pathophysiological-mechanisms-and-treatment-options
#3
Tom Tanbo, Peter Fedorcsak
Endometriosis is a common condition in women of reproductive age. In addition to pain, endometriosis may also reduce fertility. The causes of infertility in women with endometriosis may range from anatomical distortions due to adhesions and fibrosis to endocrine abnormalities and immunological disturbances. In some cases, the various pathophysiological derangements seem to interact by mechanisms so far not fully understood. Whether surgery should be offered as a treatment option in endometriosis-associated infertility has become controversial, partly due to its modest or undocumented effect...
December 20, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27979666/cesarean-scar-pregnancy-comparing-the-efficacy-and-tolerability-of-treatment-with-high-intensity-focused-ultrasound-and-uterine-artery-embolization
#4
Juhua Xiao, Zhen Shi, Jinshui Zhou, Jun Ye, Jianfang Zhu, Xin Zhou, Fang Wang, Shouhua Zhang
The aim of this study was to investigate the clinical efficacy of high-intensity focused ultrasound (HIFU) for the treatment of a cesarean scar pregnancy compared with uterine artery embolization (UAE) and intra-arterial methotrexate infusion combined with uterine curettage. In this retrospective cohort study, 31 patients were treated with HIFU (HIFU group), and 45 patients were treated with UAE (UAE group). We compared the treatment and recovery of the patients, including follow-up. After UAE treatment, serum levels of the β subunit of human chorionic gonadotropin declined significantly on the first day, and the residual lesions disappeared in 3-17 wk...
December 12, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/27856386/reproductive-outcome-in-patients-with-intrauterine-adhesions-following-hysteroscopic-adhesiolysis-experience-from-the-largest-women-s-hospital-in-china
#5
Limei Chen, Hongwei Zhang, Qing Wang, Feng Xie, Shujun Gao, Yu Song, Jing Dong, Hua Feng, Kangyun Xie, Long Sui
STUDY OBJECTIVE: To analyze the reproductive outcome of hysteroscopic adhesiolysis and assess the diagnostic accuracy of transvaginal ultrasonography (TVS) in infertile women resulting from intrauterine adhesions (IUAs) DESIGN: Retrospective , cross-sectional study (Canadian Task Force classification II-2). SETTING: University tertiary referral center PATIENTS: Three hundred and fifty seven patients with mild, moderate, and severe IUAs underwent hysteroscopic adhesiolysis between January 2012 and December 2015 INTERVENTIONS: Hysteroscopic adhesiolysis in the outpatient analgesic setting for infertility and IUAs...
November 14, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27823367/complications-associated-with-intrauterine-glass-marbles-in-five-mares
#6
Mariana Diel de Amorim, Tracey Chenier, Dawne Nairn, Jodyne Green, Stephen Manning, Claire Card
CASE DESCRIPTION 5 mares were evaluated because of reproductive complications following long-term (> 1 year) use of intrauterine glass marbles for estrus suppression. CLINICAL FINDINGS 3 mares had 1 intrauterine glass marble, and 2 mares had 2 intrauterine glass marbles. On examination, 2 mares had signs of chronic endometritis, and 3 had signs of pyometra. Marbles or glass shards adhered to the endometrium were identified by means of hysteroscopy in 3 of 5 mares. Five of 7 marbles had surface imperfections or were broken...
November 15, 2016: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/27806819/secondary-infertility-due-to-retained-fetal-bones-diagnosed-via-saline-sonography
#7
Rubina Izhar, Samia Husain, Suhaima Tahir, Sonia Husain
Prolonged intrauterine retention of any fetal bones can lead to secondary infertility. The exact incidence remains unclear. This case report describes a 36-year woman with secondary infertility of eight years. Workup revealed echogenic foci partially embedded in endometrium on saline sonography. After ultrasound guided dilation and curettage, fetal bones were retrieved. Unexplained infertility can often be explained if before applying this label, uterine factor is also taken into account. When common causes like tubal blockage, male factor, and ovulatory dysfunction have been excluded, infrequent causes like polyps, adhesions, and in rare instances foreign bodies also should be looked for...
October 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27792415/ultrasound-guided-transcervical-radiofrequency-ablation-for-symptomatic-uterine-adenomyosis
#8
Ning Hai, Qingxiang Hou, Xiaoping Ding, Xiangping Dong, Meijuan Jin
OBJECTIVE: To retrospectively evaluate the midterm outcomes of transvaginal ultrasound-guided radiofrequency ablation (RFA) for the treatment of symptomatic uterine adenomyosis. METHODS: 87 patients with symptomatic uterine adenomyosis, who met the inclusion criteria, were enrolled in our study from January 2013 to October 2015. All of the patients underwent transvaginal ultrasound-guided RFA and were followed up for 12 months. Assessment end points included uterus volume reduction rate, lesion regression rate, dysmenorrhoeal score, symptom severity score (SSS) and adverse events...
January 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/27773811/prevalence-and-impact-of-chronic-endometritis-in-patients-with-intrauterine-adhesions-a-prospective-cohort-study
#9
Yuqing Chen, Lixiang Liu, Yuanna Luo, Minghui Chen, Yang Huan, Ruili Fang
STUDY OBJECTIVE: To evaluate the prevalence and impact of chronic endometritis (CE) in patients with intrauterine adhesions (IUAs). DESIGN: Prospective cohort study (Canadian Task Force classification II-2). SETTING: University-affiliated hospital. PATIENTS: Eighty-two women with moderate to severe IUAs. INTERVENTIONS: Transcervical resection of adhesions (TCRA) and endometrial biopsy were performed in all patients...
January 1, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27742483/oxidized-regenerated-cellulose-adhesion-barrier-plus-intrauterine-device-prevents-recurrence-after-adhesiolysis-for-moderate-to-severe-intrauterine-adhesions
#10
Huihua Cai, Lin Qiao, KaiJing Song, Yuanli He
STUDY OBJECTIVE: To compare the efficacy of an oxidized, regenerated cellulose adhesion barrier (Interceed; Ethicon, Somerville, NJ) combined with an intrauterine device (IUD) versus an IUD alone for preventing adhesion recurrence following hysteroscopic adhesiolysis for moderate to severe intrauterine adhesions (IUAs). DESIGN: Retrospective case series (Canadian Task Force classification III). SETTING: Tertiary care teaching hospital. PATIENTS: Patients undergoing treatment for moderate to severe IUAs...
January 1, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27679000/application-of-ultrasonography-combined-with-hysteroscopy-in-the-middle-and-lower-segment-of-intrauterine-adhesions
#11
F Fu, H Duan
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27678980/review-of-outcomes-of-patients-treated-for-intrauterine-adhesions-with-office-hysteroscopy-and-hormone-replacement-therapy
#12
N L Noel, K B Isaacson
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27678645/hysteroscopic-procedure-for-type-i-myoma-with-intrauterine-adhesions
#13
L Montevecchi
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27670361/high-molecular-weight-hyaluronic-acid-inhibits-fibrosis-of-endometrium
#14
Yi Zhu, Jianguo Hu, Tinghe Yu, Yan Ren, Lina Hu
BACKGROUND Elevated fibrosis has been found in patients with intrauterine adhesion, which indicates that fibrotic factors may play a critical role in formation of intrauterine adhesion. The aim of this study was to identify the effect of hyaluronic acid (HA) at high and low molecular weight on fibrosis of the endometrium in a mouse model of Asherman's syndrome. MATERIAL AND METHODS Endometrial fibrosis in a mouse model of Asherman's syndrome was confirmed. Then HA at high and low molecular weight was injected into the uterine cavity...
September 27, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27668201/etiologic-characteristics-and-index-pregnancy-outcomes-of-recurrent-pregnancy-losses-in-korean-women
#15
Gi Su Lee, Joon Cheol Park, Jeong Ho Rhee, Jong In Kim
OBJECTIVE: The goal of this study was to evaluate the etiologies and clinical outcomes of Korean recurrent pregnancy loss (RPL) patients. And also, we investigated the differences between primary and secondary RPL patients, between two and three or more pregnancy losses. METHODS: One hundred seventy eight women diagnosed as RPL were enrolled. We performed chromosomal analysis, thyroid stimulating hormone, prolactin, blood glucose, plasminogen activator inhibitor-1, natural killer cell proportion, anticardiolipin antibodies, antiphospholipid antibodies, lupus anticoagulant, anti-β2glycoprotein-1 antibodies, antinuclear antibody, protein C, protein S, antithrombin III, homocysteine, MTFHR gene, factor V Leiden mutation, and hysterosalphingography/hysteroscopic evaluation...
September 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27640797/-comparison-among-measures-to-prevent-intrauterine-adhesions-after-artificial-abortion
#16
Lei Li, Manman Nai, Guixiang Gao, Luwen Wang
OBJECTIVE: To investigate the clinical efficacy of oral medicine and sodium hyaluronate in prevention of intrauterine adhesions after artificial abortion.
 METHODS: A total of 572 patients with early pregnancy termination through artificial abortion, who experienced two or more times of abortion, were retrospectively analyzed. Patients were randomly and voluntarily divided into 4 groups: an artificial cycle group, a drospirenone and ethinylestradiol tablets group, a sodium hyaluronate group, and a control group...
September 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27632410/hysteroscopic-metroplasty-for-the-septate-uterus-with-diode-laser-a-pilot-study
#17
Luigi Nappi, Alessandro Pontis, Felice Sorrentino, Pantaleo Greco, Stefano Angioni
OBJECTIVE: To evaluate the feasibility and safety of office hysteroscopic metroplasty using a 980nm diode laser. STUDY DESIGN: 18 patients were treated for septate uterus between 2013 and 2016. The indications for hysteroscopic metroplasty were recurrent abortion in 11 of the women and primary infertility in the other seven. We used a 5mm-office hysteroscope with a diode laser fibre. After exploration of the cavity, the septum was divided with use of the laser fibre...
November 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27614987/application-of-bone-marrow-derived-mesenchymal-stem-cells-in-the-treatment-of-intrauterine-adhesions-in-rats
#18
Jianmei Wang, Baohui Ju, Caijun Pan, Yan Gu, Yu Zhang, Li Sun, Bumei Zhang, Yujuan Zhang
AIMS: To investigate the therapeutic effects of bone marrow-derived mesenchymal stem cells (BMSCs) transplantation on intrauterine adhesions (IUA). METHODS: BMSCs were isolated and labeled by green fluorescence protein. IUA model was established by mechanical injury. 48 rats were randomly divided into control, IUA model, BMSCs vein injection and BMSCs intrauterine injection groups (n=12 in each group). The third generation of BMSCs was injected through tail vein or intrauterine...
2016: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/27590568/hysteroscopic-morcellation-versus-loop-resection-for-removal-of%C3%A2-placental-remnants-a-randomized-trial
#19
Tjalina W O Hamerlynck, Huib A A M van Vliet, Anne-Sophie Beerens, Steven Weyers, Benedictus C Schoot
STUDY OBJECTIVE: To compare hysteroscopic morcellation with loop resection for the removal of placental remnants in terms of procedure time, adverse events, tissue availability, histology results, short-term effectiveness, and postoperative adhesions. DESIGN: A randomized controlled trial (Canadian Task Force classification I). SETTING: A teaching and university hospital. PATIENTS: Women with placental remnants. INTERVENTIONS: Hysteroscopic morcellation with the TRUCLEAR 8...
August 30, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27486270/endometrial-stem-cells-repair-injured-endometrium-and-induce-angiogenesis-via-akt-and-erk-pathways
#20
Yanling Zhang, Xiaona Lin, Yongdong Dai, Xiaoxiao Hu, Haiyan Zhu, Yinshen Jiang, Songying Zhang
Intrauterine adhesions are common acquired endometrial syndromes secondary to endometrial injury, with limited effective therapies. Recently, several studies have reported that bone marrow stem cells (BMSCs) could repair injured endometrium in animal experiments. However, the role of stem cells in endometrial injury repair and its therapeutic mechanisms remain unclear. Here, we established mouse endometrial injury model and examined the benefit of human endometrial mesenchymal stem cells derived from menstrual blood (MenSCs) in restoration of injured endometrium...
November 2016: Reproduction: the Official Journal of the Society for the Study of Fertility
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