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https://www.readbyqxmd.com/read/29151094/glossolalia-and-aphasia-related-but-different-worlds
#1
Leila Chouiter, Jean-Marie Annoni
The word glossolalia, also referred to as "speaking in tongues," originates from the Greek "glossa" which means "language" and "Lalia" which means "speak." It simply means to talk language. On a linguistic perspective, glossolalia is characterized by almost no recognizable words or semantic content, apart from biblical words and phrases, with an overrepresentation of a small phonemes number, accelerated speech output, and modification of accents and melody. Its phonemic properties have been said to resemble those of the language(s) of the speaker...
2018: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/29105665/s-ketamine-induced-nmda-receptor-blockade-during-natural-speech-production-and-its-implications-for-formal-thought-disorder-in-schizophrenia-a-pharmaco-fmri-study
#2
Arne Nagels, Maurice Cabanis, Andrea Oppel, Andre Kirner-Veselinovic, Christian Schales, Tilo Kircher
Structural and functional changes in the lateral temporal language areas have been related to formal thought disorder (FTD) in schizophrenia. Continuous, natural speech production activates the right lateral temporal lobe in schizophrenia, as opposed to the left in healthy subjects. Positive and negative FTD can be elicited in healthy subjects by glutamatergic NMDA blockade with ketamine. It is unclear, whether the glutamate system is related to the reversed hemispheric lateralization during speaking in patients...
November 6, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29090601/expiratory-muscle-strength-training-improves-swallowing-and-respiratory-outcomes-in-people-with-dysphagia-a-systematic-review
#3
Marinda Brooks, Emma McLaughlin, Nora Shields
PURPOSE: To investigate the effects of expiratory muscle strength training on communication and swallowing outcomes in adults with acquired motor based communication and/or swallowing difficulties of any aetiology. METHOD: A systematic review was conducted. Six databases (CINAHL, MEDLINE, EMBASE, SPEECHBYTE, AMED and PUBMED) were searched from inception until end of May 2016. Randomised and non-randomised controlled studies and pre-test/post-test studies published in English that investigated the effects of expiratory muscle strength training were included...
November 1, 2017: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28994473/preliminary-thoughts-on-the-neurobiology-of-innate-unconscious-structures-and-the-psychodynamics-of-language-acquisition
#4
Susan Mizen
This paper builds upon Britton's recent writing on 'models in the mind', in which he gives an account of preverbal metaphoric structures based on object relations (Britton 2015). These correspond with Jung's theory of innate unconscious structures. These innate models are considered alongside current linguistic theory following Chomsky and post-Chomskyan views about language acquisition. Neuroscience evidence linking language and abstract thinking with structures involved in tool use are presented. The implications of these findings, and our understanding of the relational context within which language, metaphor and abstract thought are acquired, will be discussed along with the failures of symbolization and verbal communication common amongst those with severe narcissistic disorders...
November 2017: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/28979585/posterior-tibial-tendon-dysfunction-an-overview
#5
Samuel Ka-Kin Ling, Tun Hing Lui
BACKGROUND: Adult acquired flatfoot deformity is a commonly seen condition with a large clinical spectrum. It ranges from asymptomatic subjects to severely disabled arthritic patients. Posterior tibialis tendon dysfunction is a common cause of adult acquired flatfoot deformity. METHODS: This article systematically reviews the published literature from books and journals that were either originally written or later translated into the English language regarding the subject of posterior tibialis tendon dysfunction...
2017: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/28971049/korean-database-of-cerebral-palsy-a-report-on-characteristics-of-cerebral-palsy-in-south-korea
#6
Shin-Young Yim, Chung-Yong Yang, Joo Hyun Park, Min Young Kim, Yong-Beom Shin, Eun-Young Kang, Zee-Ihn Lee, Bum-Sun Kwon, Ji Chan Chang, Seong Woo Kim, Myeong-Ok Kim, Jeong-Yi Kwon, Han-Young Jung, In Young Sung
OBJECTIVE: To introduce the Korean Database of Cerebral Palsy (KDCP) and to provide the first report on characteristics of subjects with cerebral palsy (CP). METHODS: The KDCP is a nationwide database of subjects with CP, which includes a total of 773 subjects. Characteristics such as demography, birth history, onset and type of CP, brain magnetic resonance imaging (MRI) findings, functional ability and accompanying impairments, were extracted and analyzed. RESULTS: Preterm delivery and low birth weight were found in 59...
August 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28928701/teaching-literacy-skills-to-french-minimally-verbal-school-aged-children-with-autism-spectrum-disorders-with-the-serious-game-sema-tic-an-exploratory-study
#7
Sylvie Serret, Stéphanie Hun, Susanne Thümmler, Prescillia Pierron, Andreia Santos, Jérémy Bourgeois, Florence Askenazy
Learning to read is very challenging for children with Autism Spectrum Disorders (ASD), but also very important, as it can give them access to new knowledge. This is even more challenging in minimally verbal children, who do not have the verbal abilities to learn through usual methods. To address the learning of literacy skills in French minimally verbal school-aged children with ASD, we designed the serious game SEMA-TIC, which relies on non-verbal cognitive skills and uses specific learning strategies adapted to the features of autistic individuals...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28922545/neural-responses-to-linguistic-stimuli-in-children-with-and-without-autism-spectrum-disorder
#8
Kayla H Finch, Helen Tager-Flusberg, Charles A Nelson
Atypical neural responses to language have been found in toddlers with autism spectrum disorder (ASD) and in their unaffected siblings. However, given that language difficulties are often seen in these children, it is difficult to interpret whether these neural differences are a result of the diagnosis of ASD or impairments in their language abilities. In this current study, we recorded event-related potentials (ERPs) from four groups of 36-month-olds: low-risk control (LRC), high-risk for ASD defined as having an older sibling with ASD (HRA) but who do not have ASD or milder autism-like symptoms (HRA-Typ), HRA children who do not have ASD but exhibit milder autism-like symptoms (HRA-Atyp), and HRA children diagnosed with ASD (ASD)...
September 18, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28903722/eeg-power-at-3%C3%A2-months-in-infants-at-high-familial-risk-for-autism
#9
April R Levin, Kandice J Varcin, Heather M O'Leary, Helen Tager-Flusberg, Charles A Nelson
BACKGROUND: Alterations in brain development during infancy may precede the behavioral manifestation of developmental disorders. Infants at increased risk for autism are also at increased risk for other developmental disorders, including, quite commonly, language disorders. Here we assess the extent to which electroencephalographic (EEG) differences in infants at high versus low familial risk for autism are present by 3 months of age, and elucidate the functional significance of EEG power at 3 months in predicting later development...
September 13, 2017: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/28889783/sex-chromosome-changes-in-leukemia-cytogenetics-and-molecular-aspects
#10
Saeid Shahrabi, Elahe Khodadi, Fakhredin Saba, Mohammad Shahjahani, Najmaldin Saki
BACKGROUND AND OBJECTIVE: Sex chromosome loss (SCL) can occur in older men as a physiological phenomenon or as an acquired abnormality in leukemia. Loss of chromosome Y and loss of chromosome X are acquired disorders that are mainly observed in patients over 80 years as well as in myeloid and lymphoid malignancies. In this review, we examine the cytogenetic and molecular changes of sex chromosomes in leukemia. METHODS: Relevant English language literature were searched and retrieved from PubMed search engine (1990-2016)...
September 10, 2017: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/28861213/idiopathic-non-histaminergic-acquired-angioedema-a-case-series-and-discussion-of-published-clinical-trials
#11
Martin Christian Bucher, Tatjana Petkovic, Arthur Helbling, Urs Christian Steiner
BACKGROUND: Idiopathic non-histaminergic acquired angioedema (InH-AAE) is a rare disease for which there are no available laboratory parameters to clearly define the disorder. Therapy is often difficult and various treatment options have been proposed. In this paper, we have evaluated the most effective therapies for InH-AAE on the basis of current literature and report the therapeutic effect of omalizumab in three patients with InH-AAE. METHODS: Literature was searched with a combination of MeSH/EMTREE terms and freetext search for angioedema and therapy/omalizumab in the databases Medline (Ovid), PubMed/Premedline, Embase, Cochrane library and Scopus with no time or language restrictions...
2017: Clinical and Translational Allergy
https://www.readbyqxmd.com/read/28856093/from-word-reading-to-multisentence-comprehension-improvements-in-brain-activity-in-children-with-autism-after-reading-intervention
#12
Donna L Murdaugh, Jose O Maximo, Claire E Cordes, Sarah E O'Kelley, Rajesh K Kana
BACKGROUND: Children with ASD show a unique reading profile characterized by decoding abilities equivalent to verbal abilities, but with lower comprehension skills. Neuroimaging studies have found recruitment of regions primarily associated with visual processing (e.g., fusiform gyrus and medial parietal cortex), but reduced activation in frontal and temporal regions, when reading in adults with ASD. The purpose of this study was to assess neural changes associated with an intense reading intervention program in children with ASD using three fMRI tasks of reading...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28832001/acquired-epileptic-opercular-syndrome-related-to-a-heterozygous-deleterious-substitution-in-grin2a
#13
Claudine Sculier, Anne-Sophie Tilmant, Xavier De Tiège, Sanda Giurgea, Philippe Paquier, Gabrielle Rudolf, Gaetan Lesca, Patrick Van Bogaert
Epileptic encephalopathies with continuous spike-and-waves during sleep (CSWS) are characterized by cognitive or language impairment, and are occasionally associated with pathogenic variants of the GRIN2A gene. In these disorders, speech dysfunction could be either related to cerebral dysfunction caused by the GRIN2A deleterious variant or intense interictal epileptic activity. Here, we present a patient with apraxia of speech, clearly linked to severity of epilepsy, carrying a GRIN2A variant. A 6-year-old boy developed acute regression of expressive language following epileptic seizures, leading to complete mutism, at which time EEG revealed CSWS...
September 1, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/28769599/identification-of-people-with-acquired-hemophilia-in-a-large-electronic-health-record-database
#14
Michael Wang, Anissa Cyhaniuk, David L Cooper, Neeraj N Iyer
BACKGROUND: Electronic health records (EHRs) can provide insights into diagnoses, treatment patterns, and clinical outcomes. Acquired hemophilia (AH) is an ultrarare bleeding disorder characterized by factor VIII inhibiting autoantibodies. AIM: To identify patients with AH using an EHR database. METHODS: Records were accessed from a large EHR database (Humedica) between January 1, 2007 and July 31, 2013. Broad selection criteria were applied using the International Classification of Diseases, Ninth Revision, clinical modification (ICD-9-CM) code for intrinsic circulating anticoagulants (286...
2017: Journal of Blood Medicine
https://www.readbyqxmd.com/read/28654945/quantification-and-systematic-characterization-of-stuttering-like-disfluencies-in-acquired-apraxia-of-speech
#15
Dallin J Bailey, Michael Blomgren, Catharine DeLong, Kiera Berggren, Julie L Wambaugh
Purpose: The purpose of this article is to quantify and describe stuttering-like disfluencies in speakers with acquired apraxia of speech (AOS), utilizing the Lidcombe Behavioural Data Language (LBDL). Additional purposes include measuring test-retest reliability and examining the effect of speech sample type on disfluency rates. Method: Two types of speech samples were elicited from 20 persons with AOS and aphasia: repetition of mono- and multisyllabic words from a protocol for assessing AOS (Duffy, 2013), and connected speech tasks (Nicholas & Brookshire, 1993)...
June 22, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28624817/exploring-the-clinical-practice-of-speech-and-language-therapists-with-adults-with-dementia-a-cross-sectional-survey-in-portugal
#16
Jossie Nóbrega, Marisa Lousada, Daniela Figueiredo
BACKGROUND/AIMS: Adults with acquired communication and swallowing disorders secondary to dementia can benefit from speech and language therapy services. However, there is limited information on the role of speech and language therapists (SLTs) in the treatment of individuals with dementia. The aim of this study was to explore the clinical practice of SLTs with adults with dementia. METHODS: A cross-sectional survey of SLTs was conducted in Portugal using a web-based questionnaire designed specifically for the purpose of this study...
2016: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/28596753/auditory-processing-after-early-left-hemisphere-injury-a-case-report
#17
Cristina Ferraz Borges Murphy, Georgios Stavrinos, Kling Chong, Tony Sirimanna, Doris-Eva Bamiou
Few studies have addressed the long-term outcomes of early brain injury, especially after hemorrhagic stroke. This is the first study to report a case of acquired auditory processing disorder in a 10-year-old child who had a severe left hemorrhagic cerebral infarction at 13 months of age, compromising nearly all of the left temporal lobe. This case, therefore, is an excellent and rare opportunity to investigate the presence of neural plasticity of central auditory system in a developing brain followed severe brain damage...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28500672/telomere-length-and-fetal-programming-a-review-of-recent-scientific-advances
#18
Valerie E Whiteman, Anjali Goswami, Hamisu M Salihu
We sought to synthesize a comprehensive literature review comprising recent research linking fetal programming to fetal telomere length. We also explored the potential effects fetal telomere length shortening has on fetal phenotypes. Utilizing the PubMed database as our primary search engine, we retrieved and reviewed 165 articles of published research. The inclusion criteria limited the articles to those that appeared within the last ten years, were pertinent to humans, and without restriction to language of publication...
May 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/28489413/two-year-outcomes-of-poststroke-writing-and-reading-disorders
#19
Sanela Zukic, Osman Sinanovic, Lejla Zonic
Poststroke language disorders are frequent and include aphasia, alexia, agraphia, and acalculia. These disorders refer to an acquired inability to read, write and calculate. In this study, we evaluated the two year outcomes of writing and reading disorders in poststroke patients, the natural course, recovery and mortality. We evaluated all the patients with stroke who were admitted to the Department of Neurology, University Clinical Centre Tuzla in period of six months, who developed poststroke alexia, agraphia, acalculia, or different combinations of these language disorders...
May 10, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28453586/-incidence-of-aphasia-in-patients-experiencing-an-ischemic-stroke
#20
Francisca González Mc, Pablo Lavados G, Verónica Olavarría I
BACKGROUND: Sequelae after a stroke are common and may lead to disability. Aphasia - defined as an acquired language disturbance - can cause important limitations in quality of life. AIM: To describe the epidemiological features of patients who had an aphasia after a first episode of ischemic stroke and their functional outcome at six months. MATERIAL AND METHODS: Review of a database of a population study on the incidence, 30-day case fatality rate, and prognosis of stroke performed in a northern Chilean city between 2000 and 2002...
February 2017: Revista Médica de Chile
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