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Ceren Gokmenoglu, Nurdan Ozmeric, Caglar Sungur, Raziye Sahin Bildik, Imge Erguder, Serenay Elgun
OBJECTIVE: Nitric oxide (NO) is synthesized from the conversion of L-arginine to L-citrulline by NO synthase (NOS). Arginase can compete with NOS for the common substrate L-arginine, and thus inhibit NO production. NO levels and arginase ezyme might affect the bone remodeling cycle around implants. The aim of this studywas to investigate NO and arginase levels in gingival crevicular fluid (GCF), peri-implant sulcular fluid (PISF), and saliva. MATERIALS AND METHODS: Twenty patients with one or more implants (Straumann® ; Institute Straumann AG, Basel, Switzerland) restored with fixed crown prostheses were included in the study...
January 2018: Archives of Oral Biology
Arnold T Besselaar, Ralph J B Sakkers, Hans A Schuppers, Melinda M E H Witbreuk, Elgun V C M Zeegers, Jan D Visser, Robert A Boekestijn, Sacha D Margés, M C Marieke Van der Steen, Koert N J Burger
- A delegation of 6 pediatric orthopedic surgeons from the Dutch Orthopedic Association (NOV) and 2 members of the board of the Dutch Parents' Association for children with clubfoot created the guideline "The diagnosis and treatment of primary idiopathic clubfeet" between April 2011 and February 2014. The development of the guideline was supported by a professional methodologist from the Dutch Knowledge Institute of Medical Specialists. This evidence-based guideline process was new and unique, in the sense that the process was initiated by a parents' association...
June 2017: Acta Orthopaedica
B Özdemir, N Özmeric, S Elgün, E Barış
BACKGROUND: Periodontal disease pathogenesis has been associated with smoking. Gingivitis is a mild and reversible form of periodontal disease and it tends to progress to periodontitis only in susceptible individuals. In the present study, we aimed to examine the impact of smoking on host responses in gingivitis and to evaluate and compare the inducible nitric oxide synthase (iNOS) activity in gingival tissue and NO and basic fibroblast growth factor (bFGF) levels in the gingival crevicular fluid of patients with gingivitis and healthy individuals...
October 2016: Journal of Periodontal Research
Louren M Goedhart, Matthijs P Somford, Dagmar R J Kempink, A V C M Elgun Zeegers
BACKGROUND: Müller-Weiss disease is a rare and complex foot disorder. The underlying aetiology of this condition involves abnormal loading of the navicular bone combined with delayed ossification. Müller-Weiss disease is progressive and ultimately results in deformation and fragmentation of the navicular bone with plantar-flexed hindfoot varus. In patients with a severe form of this foot deformity, treatment involves arthrodesis of the midfoot with bridging of the navicular bone. CASE DESCRIPTION: A 43-year-old female patient was seen in our outpatient clinic with pain in her right foot...
2015: Nederlands Tijdschrift Voor Geneeskunde
Ismail Soner Koltas, Isın Akyar, Gullu Elgun, Tanıl Kocagoz
Direct wet mount examination and concentration are the most commonly used methods for detecting intestinal parasites from fecal samples. Concentration methods are used when there are fewer protozoan cyst, coccidian oocyst, microsporidial spore, helminth egg, and larvae in the fecal samples. Early detection of the causative intestinal parasites plays a significant role in implementing timely and correct treatment, which relieves the patients' symptoms and also prevents recurrences. Formalin-ethyl acetate concentration (FEAC) is believed to be a gold standard method to detect most intestinal parasites...
July 2014: Parasitology Research
Rola Sahyoun Tokan, Saadet Arsan, Omer Erdeve, Nuri Solaz, Aslıhan Avcı, Serenay Elgün Ulkar, Elif Gülyapar, Zeynep Ustünyurt, Zeynep Bıyıklı, Sabri Kemahlı
OBJECTIVE: This study aimed to compare the storage properties of red blood cell (RBC) concentrates of umbilical cordblood (UCB) and adult donor blood (ADB), and to evaluate the feasibility of UCB-RBC concentrate as an autologoussource for blood transfusion in very low birth weight (VLBW) preterm neonates. MATERIAL AND METHODS: In all, 30 newborn (10 preterm, 20 full term) UCB and 31 ADB units were collected.RBC concentrates were stored and compared with regard to pH, potassium (K(+)), 2,3-biphosphoglycerate (2-3-BPG),adenosine tri-phosphate (ATP), plasma Hb, and bacterial contamination on d 1, 21, and 35 of storage...
September 2012: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
Ceren Gokmenoglu, Nurdan Ozmeric, Imge Erguder, Serenay Elgun
OBJECTIVE: The purpose of this study was to determine the effect of light-emitting diode photomodulation (LED PBM) on implant osseointegration by measuring implant stability changes by resonance frequency analysis (RFA) and measuring interleukin-1β (IL-1β), transforming growth factor-β (TGF-β), prostaglandin-E2 (PGE2), and nitric oxide (NO) levels in peri-implant crevicular fluid (PICF). BACKGROUND DATA: Light therapy modulates various biological events and allows improved wound healing in ischemic and wounded tissues...
March 2014: Photomedicine and Laser Surgery
Mustafa Kürşat Demir, Adem Elgün
In this study, whole wheat bread (WWB) prepared by whole wheat flour (WWF) which its branny fraction (35 ± 1% w/w whole flour) previously was stabilized with different processes. Branny fractions obtained by milling of two different Bezostaja-1 wheat samples (medium and high strong) at 65 ± 1% wheat flour extraction ratio. These fractions were stabilized using autoclave (AU), microwave (MW), infrared (IR) and ultraviolet-C (UV-C) methods. Then, WWF obtained by remixing of stabilized branny fraction (35 ± 1% w/w) and wheat flour (65 ± 1% w/w) of same wheat samples...
January 2014: Journal of Food Science and Technology
Dagmar R J Kempink, Elgun V C M Zeegers
A 13-year-old boy came to the Emergency Department with a Salter Harris type 1 epiphysiolysis of the distal femur. These fractures can be treated with a closed reduction and possible fixation. They cause a growth disturbance in 65 % of dislocated cases and therefore should be clinically evaluated until skeletal maturity.
2012: Nederlands Tijdschrift Voor Geneeskunde
Halil I Atasoy, Mehmet Y Gunal, Pinar Atasoy, Serenay Elgun, Guler Bugdayci
OBJECTIVE: To investigate effects on rat testes of radiofrequency radiation emitted from indoor Wi-Fi Internet access devices using 802.11.g wireless standards. METHODS: Ten Wistar albino male rats were divided into experimental and control groups, with five rats per group. Standard wireless gateways communicating at 2.437 GHz were used as radiofrequency wave sources. The experimental group was exposed to radiofrequency energy for 24 h a day for 20 weeks. The rats were sacrificed at the end of the study...
April 2013: Journal of Pediatric Urology
Bulent Ulkar, Serenay Elgun, Nurdan Ozmeric, Burcu Özdemir, Duygu Boynueğri
BACKGROUND: Psychologic and physical stress is known to be related with periodontal disorders. The objective of this study is to investigate salivary and gingival crevicular fluid (GCF) nitric oxide (NO) metabolism and its association with the periodontal reaction to precompetition anxiety in competitive athletes. METHODS: A total of 18 elite male handball players participated in this study. The anxiety level of participants was determined by using a competitive state anxiety inventory-2 (CSAI-2)...
February 2012: Journal of Periodontology
Gullu Elgun, Ismail Soner Koltas
Cryptosporidium spp. is an important parasitic protozoan causing diarrhea in developing and developed countries. The agent causes severe life-threatening diarrhea especially in immunocompromised hosts. Diagnosis of the Cryptosporidium oocyst in stool samples by conventional microscopy is labor-intensive and time-consuming. Thus, we aimed to evaluate the usefulness of a copro-antigen enzyme-linked immunosorbent assay (ELISA) test in detecting Cryptosporidium spp. from fecal specimens. For this aim, microscopy and specific antigen detection methods were compared to determine Cryptosporidium spp...
February 2011: Parasitology Research
Leyla Ozer, Serenay Elgun, Burcu Ozdemir, Beste Pervane, Nurdan Ozmeric
BACKGROUND: Arginine is converted to nitric oxide (NO) via NO synthase and to ornithine via arginase. Ornithine decarboxylase (ODC) catalyzes the conversion of ornithine to polyamines. Arginase can inhibit NO production, and NO can inhibit ODC activity as part of an early inflammatory response. This study examines the arginine-NO-polyamine pathway alteration in saliva and gingival biopsy samples of patients with gingivitis or periodontitis and healthy controls and evaluates the response to periodontal treatment...
February 2011: Journal of Periodontology
Nurdan Ozmeric, Nur Mollaoglu, Serenay Elgun, Erdinc Devrim
OBJECTIVE AND DESIGN: Nitric oxide (NO) has been linked to inflammatory reactions, tissue destruction, host defense, and wound healing in oral diseases. It is known that arginase enzyme controls the synthesis of NO through arginine depletion. This study evaluated the arginase-NO pathway alteration in response to tissue injury after dental extraction surgery and the effect of postoperative use of 0.2% chlorhexidine gluconate rinse (CHX). MATERIALS AND METHODS: This study included 28 individuals who had impacted mandibular third molars...
June 2010: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
Elif Küpeli, Demet Karnak, Serenay Elgün, Emine Argüder, Oya Kayacan
Measurement of pleural fluid adenosine deaminase (ADA) levels aids diagnosing tuberculous pleural effusion (TPE). Dipeptidyl peptidase IV (DPP) enzyme is closely related to ADA. Our aim was to determine the value of concurrent measurement of these T-cell-associated enzymes, ADA and DPP levels in the diagnosis of TPE. Patients with pleural effusion were grouped as TPE, parapneumonic, malignant, congestive heart failure related, and miscellaneous pleural effusions. Pleural and serum ADA and DPP levels were measured...
December 2009: Diagnostic Microbiology and Infectious Disease
Fadime Eroglu, Ahmet Genc, Gullu Elgun, Ismail Soner Koltas
Despite years of study, the pathogenic role of Blastocytis hominis is still controversial. Genotypic differences between the asymptomatic and symptomatic isolates should assist in determining the pathogenicity of Blastocystis. In this study, we genotyped 32 Blastocystis isolates obtained from 12 asymptomatic healthy individuals and 20 symptomatic patients pain by polymerase chain reaction using known seven kinds of sequence tagged site primers in this study. When we compared genotype of Blastocystis isolates between the symptomatic and asymptomatic patient group, we found that subtype3 is the most dominant genotype in asymptomatic individual (9/12) and subtype1 determined all of symptomatic patients (20/20)...
November 2009: Parasitology Research
Omür O Uçakhan, Ayfer Kanpolat, Serenay Elgün, Ilker Durak
BACKGROUND: To evaluate the role of light-induced oxidative mechanisms in the pathogenesis of primary pterygium. METHODS: Pterygium specimens were obtained from 18 eyes of 18 patients undergoing pterygial removal (group A), and normal conjunctival specimens were obtained from 18 eyes of 18 patients undergoing cataract surgery (group B). In all specimens, malondialdehyde (MDA) levels, superoxide dismutase (SOD) and catalase (CAT) activities were studied and compared...
2009: Ophthalmologica. Journal International D'ophtalmologie
Asli Yolaç Yarpuz, Ayşegül Yilmaz, Atilla Soykan, Serenay Elgün, Hakan Kumbasar
OBJECTIVE: Adenosine deaminase and dipeptidyl peptidase IV are enzymes connected to T cells that play an important role in immune system functioning. In this study, in order to understand the immune processes in panic disorder, we determined the serum levels of adenosine deaminase and dipeptidyl peptidase IV in medication-free panic disorder patients and compared them to those of healthy controls. METHOD: Enzymes levels were determined in blood samples of 24 healthy controls and 33 panic disorder patients diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders-IV that were medication free during the previous month and medically healthy...
2008: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
S Elgün, B Kaçmaz, I Durak
SETTING: Tuberculous pleural effusion leads to an immune response involving mainly immune and mesothelial cells. Nitric oxide (NO) produced by these cells may have antimycobacterial effects against Mycobacterium tuberculosis. OBJECTIVE: To investigate the possible role of NO in connection with the arginase enzyme, which controls the synthesis of NO through arginine depletion. DESIGN: Pleural fluid samples from 20 patients with tuberculous pleural effusion were used for arginase activity and NO level determination...
March 2005: International Journal of Tuberculosis and Lung Disease
Cigdem Güllü, Nurdan Ozmeric, Benay Tokman, Serenay Elgün, Köksal Balos
BACKGROUND: Nitric oxide (NO) is synthesized from the conversion of L-arginine to L-citrulline by NO synthase (NOS). Arginase, which is an arginine-depleting enzyme, can compete with NOS for the common substrate L-arginine and thus inhibit NO production. OBJECTIVES: In the present study, we aimed to examine the correlation between the arginase and NOS activity in patients with chronic periodontitis and to compare the effects of scaling and root planing and modified Widman flap procedures on enzyme activity...
April 2005: Journal of Periodontal Research
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