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https://www.readbyqxmd.com/read/28213202/determinants-of-cough-effectiveness-in-patients-with-respiratory-muscle-weakness
#1
Franco Laghi, Veeranna Maddipati, Timothy Schnell, W Edwin Langbein, Martin J Tobin
Experiments were undertaken to mechanistically define expiratory-muscle contribution to effectiveness of cough while controlling glottic movement. We hypothesized that electrical abdominal-muscle stimulation in patients with respiratory-muscle weakness produces effective coughs only when glottic closure accompanies coughs. In ten spinal-cord-injury patients, esophago-gastric pressure and airflow were recorded during solicited-coughs, coughs augmented by abdominal-muscle stimulation, and passive open-glottis exhalations...
February 14, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28207549/stylet-angulation-for-routine-endotracheal-intubation-with-mcgrath-videolaryngoscope
#2
Jiyoung Lee, Jong Yeop Kim, Se Yoon Kang, Hyun Jeong Kwak, Dongchul Lee, Sook Young Lee
BACKGROUND: The McGrath videolaryngoscope (VL) provides excellent laryngoscopic views, but directing an endotracheal tube can be difficult, and thus the routine use of a stylet is recommended. The goal of this study is to determine the appropriate angle (60° vs 90°) of the stylet when using the McGrath VL by comparing the time to intubation (TTI). METHODS: One hundred and forty patients aged 19 to 70 years (American Society of Anesthesiologists classification I or II) who required tracheal intubation for elective surgery were randomly allocated to 1 of 2 groups, at the 60° angle (n = 70) or the 90° angle (n = 70)...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28199035/utility-approach-to-decision-making-in-extended-t1-and-limited-t2-glottic-carcinoma
#3
Yda van Loon, Anne M Stiggelbout, Marieke M Hakkesteegt, Ton P M Langeveld, Rob J Baatenburg de Jong, Elisabeth V Sjögren
BACKGROUND: It is still undecided if endoscopic laser surgery or radiotherapy is the preferable treatment in extended T1 and limited T2 glottic tumors. Health utilities assessed from patients can aid in decision-making. METHODS: Patients treated for extended T1 or limited T2 glottic carcinoma by laser surgery (n = 12) or radiotherapy (n = 14) assigned health utilities using a visual analog scale (VAS), time tradeoff (TTO) technique and scored their voice handicap using the Voice Handicap Index (VHI)...
February 15, 2017: Head & Neck
https://www.readbyqxmd.com/read/28195018/glottic-closing-force-versus-laryngeal-adductory-pressure-in-the-canine-larynx
#4
Randal C Paniello, Neel K Bhatt
INTRODUCTION: The strength of glottic closure with recurrent laryngeal nerve (RLN) stimulation has been indirectly measured experimentally by determining the squeezing pressure on a balloon inserted between the vocal folds, termed laryngeal adductory pressure (LAP). In this study, we sought to measure glottic closing force (GCF) directly and compare these results to LAP measures obtained with identical stimulation parameters. METHODS: In canines, a method for measuring GCF was developed in which a suture was looped through a lateral thyrotomy hole, around the vocal process and back, then attached to a force gauge...
March 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28193302/outcomes-of-transoral-laser-microsurgical-management-of-t1b-stage-glottic-cancer
#5
J A Song, M H Rigby, J Trites, R D Hart, S M Taylor
OBJECTIVE: This study aimed to evaluate the oncological and voice outcomes of transoral laser microsurgery for tumour stage T1b stage glottic cancer patients. METHODS: A prospective cohort study in a tertiary care head and neck cancer centre included tumour-node-metastasis stage T1bN0M0 glottic cancer patients scheduled to undergo transoral laser microsurgery from January 2002 until June 2014. Kaplan-Meier five-year analyses of local control, overall survival, disease-specific survival and laryngeal preservation were performed...
February 14, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28187213/a-comparison-of-the-airtraq%C3%A2-mcgrath%C3%A2-and-macintosh-laryngoscopes-for-difficult-paediatric-intubation-a-manikin-study
#6
Gen Owada, Takahiro Mihara, Gaku Inagawa, Ayako Asakura, Takahisa Goto, Koui Ka
BACKGROUND: The efficacy of devices for difficult intubation in paediatric patients, especially with a Cormack-Lehane grade 4 view, has yet to be established. We compared intubating parameters among three devices (the Airtraq®, McGrath®, and Macintosh laryngoscopes). METHODS: This study is a randomised cross-over trial. Participants were 20 anaesthetists. Each device was tested three times using a paediatric manikin with a Cormack-Lehane grade 4 view. The order to use each device was randomised by a computer-generated random sequence...
2017: PloS One
https://www.readbyqxmd.com/read/28183552/comparison-of-the-macintosh-and-airtraq-laryngoscopes-in-morbidly-obese-patients-a-randomized-and-prospective-study
#7
Caridad G Castillo-Monzón, Hugo A Marroquín-Valz, Miguel Fernández-Villacañas-Marín, Matilde Moreno-Cascales, Blas García-Rojo, César A Candia-Arana
STUDY OBJECTIVE: Morbid obesity is associated with a difficult management of the airway. There is no agreement on these patients being difficult to intubate, but if they are difficult to ventilate with facial mask, then the fast control of their airway becomes a priority. This study compares the quickness and success in tracheal intubation, glottic view, hemodynamic response, and complications from the use of the Macintosh and Airtraq laryngoscopes in morbidly obese patients for scheduled surgery...
February 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28177326/supracricoid-laryngectomy-for-recurrent-laryngeal-cancer-after-chemoradiotherapy-a-systematic-review-and-meta-analysis
#8
C A Leone, P Capasso, D Topazio, G Russo
Residual or recurrent laryngeal cancer after irradiation is a difficult clinical problem with a rate that ranges from 13% to 36% of cases. Supracricoid laryngectomy (SCL) with cricohyoidopexy (CHP) or cricohyoidoepiglottopexy (CHEP) provide reliable oncological and functional results for selected primary and recurrent patients with glottic and supraglottic carcinomas. We conducted a systematic review and meta-analysis to assess the oncological and functional outcomes of patients treated with open partial horizontal laryngectomy types IIa and IIb (CHEP, CHP) in terms of the recurrence of squamocellular cancer of the larynx after radiotherapy failure...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28169863/supratracheal-partial-laryngectomy-indications-oncologic-and-functional-results
#9
Giovanni Succo, Marco Fantini, Giuseppe Rizzotto
PURPOSE OF REVIEW: To describe current evidence about supratracheal laryngectomies, focusing on indications, contraindications, oncologic results, functional outcomes and side-effects of this 'extreme' function-sparing surgical approach to laryngeal cancer. RECENT FINDINGS: In the latest years, some studies have analyzed oncologic and functional results of open partial supratracheal laryngectomy, a surgical approach whose modern technique was recently described...
February 4, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28169008/relationship-of-medial-versus-superior-vocal-cord-location-of-t1-squamous-cell-carcinoma-with-tumor-recurrence
#10
Uri Alkan, Yuval Nachalon, Aron Popovtzer, Sharon Tzelnick, Dan Yaniv, Jacob Shvero
OBJECTIVE: To determine if the clinical behavior of T1 glottic squamous cell carcinoma varies by its location on the medial free edge or upper aspect of the vocal cords. STUDY DESIGN: Retrospective cohort. SETTING: Single tertiary university-affiliated medical center. SUBJECTS AND METHODS: Clinical, treatment, and outcome data were collected for 104 patients with T1N0M0 glottic squamous cell carcinoma who were treated and followed at our center in 1995-2013...
February 2, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28166396/elmo3-predicts-poor-outcome-in-t1-laryngeal-cancer
#11
Georg Haymerle, Lorenz Kadletz, Robert Wiebringhaus, Bahar Golabi, Michael Mildner, Dietmar Thurnher, Gregor Heiduschka
OBJECTIVES: Despite the excellent overall survival of 92-97% in early glottic cancer, recurrence rates of 13-20% have not improved in the last decades. The engulfment and cell motility protein 3 (ELMO3) has been described as prognostic marker in lung cancer patients. The aim of this study was to investigate the expression of ELMO3 in early laryngeal cancer patients treated with TLM and to evaluate its prognostic significance on clinical outcome. DESIGN, SETTING AND PARTICIPANT: 48 patients with glottic carcinoma (T1N0M0) that underwent primary treatment with TLM between 1994 and 2012 were analyzed...
February 6, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28153526/two-stage-co2-laser-assisted-bilateral-cordectomy-for-ct1b-glottic-carcinoma
#12
Andy Bertolin, Marco Lionello, Gianni Salis, Giuseppe Rizzotto, Marco Lucioni
PURPOSE: The aim of the present paper was to investigate the oncological safety of two-stage bilateral cordectomy for the treatment of cT1b glottic SCC, and to compare its oncological outcome and synechia development rate with those of single-stage procedures. MATERIALS AND METHODS: A retrospective cohort study was performed at the Otolaryngology Unit of Vittorio Veneto Laryngeal Cancer Center (Italy). The prognostic significance of clinical, pathological and surgical factors was also investigated, in terms of recurrence rate and disease-free survival, in a univariate statistical setting...
January 18, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28139308/simple-method-for-obtaining-the-optimal-laryngoscopic-view-in-children-a-prospective-observational-study
#13
Eun-Hee Kim, Sang-Hwan Ji, In-Kyung Song, Ji-Hyun Lee, Jin-Tae Kim, Hee-Soo Kim
BACKGROUND: Head and neck positioning has an important effect on laryngeal visualization during laryngoscopy. For small children and infants, a head-flat position is traditionally assumed; however, during laryngoscopy, the optimal head position may result in a superior laryngeal view in certain patients. METHODS: We investigated whether the alignment of the external auditory meatus and the sternal notch with a pillow with an individualized height is associated with improved laryngeal visualization during direct laryngoscopy in pediatric patients...
January 24, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28122353/matched-pair-analysis-of-survival-in-patients-with-poorly-differentiated-versus-well-differentiated-glottic-squamous-cell-carcinoma
#14
Ping Chen, Wenbin Yu, Junwei Huang, Hongbo Xu, Guojun Li, Xiaohong Chen, Zhigang Huang
To compare survival outcomes between patients with poorly differentiated versus well-differentiated glottic squamous cell carcinoma (GSCC). Fifty-five patients with well-differentiated newly diagnosed GSCC were pair-matched to 55 patients with poorly differentiated GSCC according to age, sex, year of diagnosis, overall stage, treatment (surgery type, neck dissection, surgical margin, and chemoradiation), smoking, and alcohol use. Survival analysis was performed using Kaplan-Meier estimates, and matched-pair survival was estimated using the Cox proportional hazards regression model...
January 20, 2017: Oncotarget
https://www.readbyqxmd.com/read/28110846/prognostic-role-of-margin-status-in-open-and-co2-laser-cordectomy-for-t1a-t1b-glottic-cancer
#15
Vincenzo Landolfo, Carmine Fernando Gervasio, Giuseppe Riva, Massimiliano Garzaro, Rita Audisio, Giancarlo Pecorari, Roberto Albera
INTRODUCTION: Cordectomy by laringofissure and transoral laser surgery has been proposed for the treatment of early glottic cancer. OBJECTIVES: The aim of this retrospective study was to evaluate the prognostic value of margin status in 162 consecutive cases of early glottic carcinoma (Tis-T1) treated with CO2 laser endoscopic surgery (Group A) or laryngofissure cordectomy (Group B), and to compare the oncologic and functional results. METHODS: Clinical prognostic factors, local recurrence rate according to margin status, overall survival and disease-free survival were analyzed...
December 24, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28100072/trial-vocal-fold-injection-predicts-thyroplasty-outcomes-in-nonparalytic-glottic-incompetence
#16
Lukas D Dumberger, Lewis Overton, Robert A Buckmire, Rupali N Shah
OBJECTIVES: Trial vocal fold injection (TVFI) may be used prior to permanent medialization when voice outcome is uncertain. We aimed to determine whether voice outcomes of TVFI are predictive of, or correlate with outcomes after type I Gore-Tex medialization thyroplasty (GMT) in patients with nonparalytic glottic incompetence (GI). METHODS: Thirty-five patients with nonparalytic GI who underwent TVFI followed by GMT were retrospectively reviewed. Change in voice-related quality of life (VRQOL) after TVFI was compared to change in VRQOL 3 to 9 months after GMT...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28089425/-a-comparison-of-various-supraglottic-airway-devices-for-fiberoptical-guided-tracheal-intubation
#17
Thomas Metterlein, Anna Dintenfelder, Christoph Plank, Bernhard Graf, Gabriel Roth
BACKGROUND: Fiberoptical assisted intubation via placed supraglottic airway devices has been described as safe and easy procedure to manage difficult airways. However visualization of the glottis aperture is essential for fiberoptical assisted intubation. Various different supraglottic airway devices are commercially available and might offer different conditions for fiberoptical assisted intubation. The aim of this study was to compare the best obtainable view of the glottic aperture using different supraglottic airway devices...
January 12, 2017: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28073284/posterior-glottic-insufficiency-in-children
#18
Reema Padia, Marshall E Smith
BACKGROUND: Dysphonia secondary to posterior glottic insufficiency (PGI) can be difficult to identify and correct. Inadequate arytenoid approximation from medial arytenoid erosion results in a breathy, soft voice. The anatomical location of the gap is difficult to correct by vocal fold injection laryngoplasty. This study reviews the presentation, evaluation, and treatment for pediatric patients who were identified with PGI. METHODS: An Institutional Review Board-approved chart review was performed on all patients who were diagnosed with PGI at our institution from 2013 to 2015...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28069084/transoral-laser-resection-of-glottic-carcinoma-what-is-the-significance-of-anterior-commissure-involvement
#19
K A Stephenson, J J Fagan
BACKGROUND: The optimal management of glottic carcinoma involving the anterior commissure is controversial. METHOD: A retrospective analysis was conducted of 76 patients with glottic squamous cell carcinoma treated by transoral carbon dioxide laser resection by a single surgeon. RESULTS: Sixty-three patients (with tumour stage Tis-T3) were eligible for inclusion. Thirty patients had involvement of the anterior commissure; these patients were significantly more likely to have either uncertain or positive margins (63...
February 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28028675/glottic-impersonation
#20
George Kovacs, Laura V Duggan, Peter G Brindley
No abstract text is available yet for this article.
March 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
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