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https://www.readbyqxmd.com/read/28721883/patterns-of-care-for-patients-with-early-stage-glottic-cancer-undergoing-definitive-radiation-therapy-a-national-cancer-database-analysis
#1
William A Stokes, Diana Abbott, Andy Phan, David Raben, Ryan M Lanning, Sana D Karam
PURPOSE: To characterize practice patterns, including temporal trends, in fractionation schedules among patients in the United States undergoing definitive radiation therapy for early-stage glottic cancer and to compare overall survival outcomes between fractionation schedules. METHODS AND MATERIALS: We queried the National Cancer Database for patients with TisN0M0, T1N0M0, or T2N0M0 squamous cell carcinoma of the glottic larynx diagnosed between 2004 and 2012 and undergoing definitive radiation therapy...
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28715529/changes-in-peak-airflow-measurement-during-maximal-cough-after-vocal-fold-augmentation-in-patients-with-glottic-insufficiency
#2
Gregory R Dion, Efstratios Achlatis, Stephanie Teng, Yixin Fang, Michael Persky, Ryan C Branski, Milan R Amin
Importance: Compromised cough effectiveness is correlated with dysphagia and aspiration. Glottic insufficiency likely yields decreased cough strength and effectiveness. Although vocal fold augmentation favorably affects voice and likely improves cough strength, few data exist to support this hypothesis. Objective: To assess whether vocal fold augmentation improves peak airflow measurements during maximal-effort cough following augmentation. Setting, Design, Participants: This case series study was conducted in a tertiary, academic laryngology clinic...
July 13, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28712704/impact-of-perioperative-voice-therapy-on-outcomes-in-the-surgical-management-of-vocal-fold-cysts
#3
Kathleen M Tibbetts, Laura M Dominguez, C Blake Simpson
INTRODUCTION: Vocal fold cysts are benign mid-membranous lesions of the true vocal fold, classified as mucus retention or epidermal inclusion cysts. Treatment is surgical excision with or without postoperative voice therapy. METHODS: A retrospective review was performed of the demographics, treatment approach, and outcomes of patients treated for vocal fold cysts between 2009 and 2014. Voice Handicap Index (VHI)-10 scores before and after treatment were compared using the Wilcoxon Rank-Sum test and the two-tailed Student's t test...
July 13, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28708883/impact-of-stage-management-and-recurrence-on-survival-rates-in-laryngeal-cancer
#4
Jesper Brandstorp-Boesen, Ragnhild Sørum Falk, Morten Boysen, Kjell Brøndbo
A retrospective, longitudinal study of 1,616 patients with primary laryngeal squamous cell carcinoma (LSCC) at a single center in Norway during 1983-2010 was undertaken to investigate overall survival, disease specific survival, disease-free survival, prognostic factors for overall survival, and impact of recurrence among all-stage laryngeal cancer patients over 15 years' follow-up. The prognostic impact of gender, age, smoking/alcohol, subsite, tumour, node and metastasis staging, period and modality of treatment were evaluated using Kaplan-Meier and Cox proportional hazard analyses...
2017: PloS One
https://www.readbyqxmd.com/read/28699172/outcomes-of-medialization-laryngoplasty-with-and-without-arytenoid-adduction
#5
Joseph Chang, Sarah L Schneider, James Curtis, Jonelyn Langenstein, Mark S Courey, Katherine C Yung
OBJECTIVES/HYPOTHESIS: To evaluate the effect of medialization laryngoplasty (ML) performed alone compared to ML with arytenoid adduction (AA) on glottic gap and voice quality in unilateral vocal fold paralysis (UVFP) patients. STUDY DESIGN: Retrospective case series. METHODS: UVFP patients treated with ML alone and ML with AA at the University of California San Francisco Voice and Swallowing Center were identified. Demographic information and history of laryngeal procedures were collected...
July 12, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28695785/ct-study-of-the-arytenoid-cartilage-in-patients-with-laryngeal-contact-granuloma
#6
Jinrang Li, Shiyu Tian, Shizhen Zou, Qingjun Wang, Xuhui Tai, Xuesong Chen
Objective To explore high-resolution computed tomography (HRCT) characteristics of arytenoid cartilage in patients with laryngeal contact granuloma (LCG). Setting Tertiary hospitals. Study Design Individual case-control study. Methods HRCT scans were obtained before treatment from 42 patients with LCG. Similar scans were obtained from 50 patients with glottic laryngeal cancer or vocal cord leukoplakia without vocal process involvement. Results Forty-two male patients with LCG were enrolled in the study. There were 41 patients with unilateral vocal cord lesions, and 1 patient had bilateral lesions...
July 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28695624/life-quality-improvement-in-hoarse-patients-with-early-glottic-cancer-after-transoral-laser-microsurgery
#7
Li-Jen Hsin, Wan-Ni Lin, Tuan-Jen Fang, Li-Ang Lee, Chung-Jan Kang, Bing-Shan Huang, Chien-Yu Lin, Kang-Hsing Fan, Ngan-Ming Tsang, Cheng-Lung Hsu, Joseph Tung-Chieh Chang, Chun-Ta Liao, Tzu-Chen Yen, Kai-Ping Chang, Hsiu-Feng Chuang, Hsueh-Yu Li
BACKGROUND: The purpose of this study was to evaluate the recovery kinetics of voice and quality of life (QOL) over time in patients with early glottic cancer who underwent transoral laser microsurgery (TLM). METHODS: A prospective cohort study was conducted in which acoustic and aerodynamic voice assessments and QOL analyses were done using health-related questionnaires (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30-questions [EORTC-QLQ-C30] and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Head and Neck 35-questions [EORTC-QLQ-H&N35]) were administered at designated times...
July 11, 2017: Head & Neck
https://www.readbyqxmd.com/read/28687381/operative-procedure-of-anterior-commissure-for-type-ii-thyroplasty
#8
Koji Matsushima, Nobuhiko Isshiki, Masahiro Tanabe, Naoto Yoshizaki, Kazuya Otsu, Akira Fukuo, Kentaro Matsuura, Yusuke Watanabe, Kiminori Sato
OBJECTIVE: We reviewed the clinical anatomy of the anterior commissure and examined the effectiveness of a specialized spreader developed for optimal, efficient spreading of the thyroid cartilage in type II thyroplasty. STUDY DESIGN AND METHODS: The present study was a multicenter retrospective study of patients with spasmodic dysphonia who underwent a primary operation either before or after the introduction of a specialized spreader (in 2008 or 2014, respectively)...
July 4, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28669149/current-treatment-options-for-bilateral-vocal-fold-paralysis-a-state-of-the-art-review
#9
Yike Li, Gaelyn Garrett, David Zealear
Vocal fold paralysis (BVFP) refers to neurological causes of reduced or absent movement of one or both vocal folds. Bilateral BVFP is characterized by inspiratory dyspnea due to narrowing of the airway at the glottic level with both vocal folds assuming a paramedian position. The primary objective of intervention for BVFP is to relieve patients' dyspnea. Common clinical options for management include tracheostomy, arytenoidectomy and cordotomy. Other options that have been used with varying success include reinnervation techniques and botulinum toxin (Botox) injections into the vocal fold adductors...
July 4, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28668461/lateral-cervical-approach-for-supracricoid-partial-laryngectomy
#10
Giuseppe Spriano, Giuseppe Mercante, Giovanni Cristalli, Raul Pellini, Fabio Ferreli
INTRODUCTION: The supracricoid partial laryngectomy has been described for the treatment of T3 laryngeal glottic and supraglottic tumors as well as upfront and salvage surgery. Good oncological and functional outcomes are expected, while the post-operative rehabilitation can be quite difficult for the patient. Early and late complications can occur especially in salvage surgery. Neck dissection according to the T stage is often associated with the resection of the primary tumor. OBJECTIVE: To verify the feasibility of a minimally invasive procedure for supracricoid partial laryngectomy by adopting the lateral cervical approach...
June 27, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28660173/evaluating-post-radiotherapy-laryngeal-function-with-laryngeal-videostroboscopy-in-early-stage-glottic-cancer
#11
Ariel E Marciscano, Vivek Charu, Heather M Starmer, Simon R Best, Harry Quon, Alexander T Hillel, Lee M Akst, Ana P Kiess
OBJECTIVE: Dysphonia is common among patients with early stage glottic cancer. Laryngeal videostroboscopy (LVS) has not been routinely used to assess post-radiotherapy (RT) voice changes. We hypothesized that LVS would demonstrate improvement in laryngeal function after definitive RT for early-stage glottic cancer. STUDY DESIGN: Blinded retrospective review of perceptual voice and stroboscopic parameters for patients with early glottic cancer and controls. SETTING: High-volume, single-institution academic medical center...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28658820/a-misdiagnosed-laryngeal-web-treated-with-an-innovative-self-made-keel
#12
Kartik Anil Parelkar, Vandana P Thorawade, Keya A Shah, Ankur K Walli, Ankur H Pareek
Laryngeal web is a rare congenital anomaly. Late presentation at the age of 10 years as in our case, with misleading diagnosis of asthma in a Cohen's type III glottic web is even rarer. In cases of congenital laryngeal web the aim is to provide a patent airway and to achieve a good voice quality. Regardless of the technique used; the primary concern is recurrence. Traditionally, the treatment of choice for laryngeal web was laryngofissure with placement of a keel however; endoscopic laser excision of the web with keel placement is now the preferred technique for thin anterior glottic webs...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28655086/-clinical-study-of-smt-%C3%A2-video-laryngoscope-with-difficult-airway-intubation-in-emergency-department
#13
J H Yu, Y Wang
Objective: To observe the clinical feasibility and security of SMT-Ⅱ video laryngoscope in difficult airway intubation in emergency department. Methods: This study took 90 adults with difficult airway who were admitted to the rescue room of Jingxi court of Beijing Chao-Yang Hospital, Capital Medical University from January 2015 to December 2016.The patients were randomly divided into 2 groups(SMT-Ⅱ video laryngoscope group: n=45, Macintosh direct laryngoscope group: n=45), which were treated with endotracheal intubation and ventilator assisted ventilation...
July 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28653453/ahns-series-do-you-know-your-guidelines-principles-of-treatment-for-glottic-cancer-a-review-of-the-national-comprehensive-cancer-network-guidelines
#14
Jessica Yesensky, Nishant Agrawal, Semirra Bayan, Elizabeth Blair, Louis Portugal, Jason Chan, David Goldenberg, Zhen Gooi
This article is a continuation of the "Do You Know Your Guidelines" series, an initiative of the American Head and Neck Society's Education Committee to increase awareness of current best practices pertaining to head and neck cancer. The National Comprehensive Cancer Network (NCCN) guidelines for primary and adjuvant treatment of cancer of the glottic larynx are reviewed here in a systematic fashion according to stage.
June 27, 2017: Head & Neck
https://www.readbyqxmd.com/read/28648812/neck-metastasis-in-patients-with-t1-2-supraglottic-cancer
#15
Tomoyasu Tachibana, Yorihisa Orita, Hidenori Marunaka, Sei-Ichiro Makihara, Misato Hirai, Yuka Gion, Kana Ikegami, Kentaro Miki, Takuma Makino, Yasuyuki Noyama, Yasutoshi Komatsubara, Miyuki Kimura, Tadashi Yoshino, Kazunori Nishizaki, Yasuharu Sato
OBJECTIVES: Unlike glottic cancer, supraglottic cancer often presents with neck metastases. This different might be attributable to the location of the primary lesion. This study aimed to clarify the relationships between the sublocation of T1-2 supraglottic cancer, human papillomavirus (HPV) infection, neck metastasis, and prognosis of supraglottic cancer. METHODS: This retrospective clinical study investigated 55 Japanese patients with T1-2 supraglottic cancer treated between 1994 and 2015...
June 22, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28631160/role-of-imaging-in-the-follow-up-of-t2-t3-glottic-cancer-treated-by-transoral-laser-microsurgery
#16
Filippo Marchi, Cesare Piazza, Marco Ravanelli, Giovanna Gaggero, Giampiero Parrinello, Alberto Paderno, Pietro Perotti, Marta Filauro, Roberto Maroldi, Giorgio Peretti
An unblinded retrospective analysis of prospectively collected data was carried out on 138 patients affected by glottic pT2 and selected pT3 squamous cell carcinomas (SCC) treated by transoral laser microsurgery (TLM). The entire cohort was divided into two groups: Group A included 78 "high-risk" patients (pT2 with impaired vocal cord mobility, pT3 for anterior paraglottic and/or pre-epiglottic space invasion, presence of angioembolization, perineural spread, and positive lymph nodes in the neck) who underwent postoperative surveillance by endoscopy and imaging (CT or MR), while Group B included 60 "low-risk" patients (pT2 with absence of the above-mentioned features) who underwent endoscopic follow-up alone...
June 19, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28629915/video-laryngoscopy-for-endotracheal-intubation-of-critically-ill-adults-a-systemic-review-and-meta-analysis
#17
Hui-Bin Huang, Jin-Min Peng, Biao Xu, Guang-Yun Liu, Bin Du
BACKGROUND: Endotracheal intubation (EI) in ICU patients is associated with an increased risk of life-threatening adverse events due to unstable conditions, rapid deterioration, limited preparation time, and variability in the expertise of operators. The goal of this study was to compare the effect of video laryngoscopy (VL) and direct laryngoscopy (DL) in ICU patients requiring EI. METHODS: We searched for relevant studies in PubMed, Embase, and the Cochrane database from inception through January 30, 2017...
June 16, 2017: Chest
https://www.readbyqxmd.com/read/28624315/coexisting-vocal-fold-polyps-and-sulcus-vocalis-coincidence-or-coexistence-characteristics-of-14-patients
#18
Narin Nard Carmel-Neiderman, Oshri Wasserzug, Tomer Ziv-Baran, Yael Oestreicher-Kedem
OBJECTIVE: The study aimed (1) to evaluate the prevalence of sulcus vocalis (SV) coexisting with vocal fold polyp (SV-VFP), and (2) to determine the effect of their coexistence on voice quality. STUDY DESIGN: This is a retrospective cohort study in a tertiary referral center. METHODS: The medical records of all patients who underwent micro direct laryngoscopy due to VFPs between January 2013 and April 2015 were reviewed. Patients with SV-VFP were identified and data of their demographics, medical history, habits, preoperative and intraoperative laryngeal findings, and pre- and postoperative GRBAS (Grade, Roughness, Breathiness, Asthenia, Strain) score, and compared with the data of patients with solitary VFPs (S-VFPs)...
June 14, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28622152/use-of-transnasal-humidified-rapid-insufflation-ventilatory-exchange-for-emergent-surgical-tracheostomy-a-case-report
#19
Neel Desai, Anna Fowler
Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) is a novel airway technique that utilizes high-flow humidified nasal oxygen. It can extend apnea time and maintain oxygen saturation. Here we report the use of THRIVE in a 35-year-old man who required emergent surgical tracheostomy for a clinically relevant compromised airway secondary to acute supraglottic and glottic pathology. Intravenous sedation resulted in hypoventilation close to apnea. THRIVE maintained oxygen saturation for 40 minutes until transient desaturation developed after complete airway obstruction...
June 15, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28609773/transoral-robotic-surgery-total-laryngectomy-evaluation-of-functional-and-survival-outcomes-in-a-retrospective-case-series-at-a-single-institution
#20
Giri Krishnan, Suren Krishnan
BACKGROUND: Transoral robotic surgery total laryngectomy (TORS-TL) is a minimally invasive endoscopic surgical approach which can theoretically minimise the morbidity of large external incisions and limit dissection of tissue planes so as to reduce the risk of pharyngocutaneous fistulae related to poor tissue healing secondary to radiation soft tissue injury or malnutrition. The purpose of this paper was to report our experience with this uncommon surgical approach. METHODS: A retrospective chart review was conducted at a single institution to evaluate the functional and survival outcomes of a series of patients who underwent TORS-TL...
June 14, 2017: ORL; Journal for Oto-rhino-laryngology and its related Specialties
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