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https://www.readbyqxmd.com/read/29792830/subglottic-resections-how-i-teach-it
#1
EDITORIAL
Konrad Hoetzenecker, Walter Klepetko
Surgical treatment of stenosis of the laryngotracheal junction can be challenging. Success is not only measured by the patency of the airway but also by preservation of the full functional capacity of the larynx. This unique feature of subglottic resections requires a close cooperation with speech-language pathologists and ENT specialists.
May 21, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29785504/impact-of-a-vap-bundle-in-belgian-intensive-care-units
#2
Laurent Jadot, Luc Huyghens, Annick De Jaeger, Marc Bourgeois, Dominique Biarent, Adeline Higuet, Koen de Decker, Margot Vander Laenen, Baudewijn Oosterlynck, Patrick Ferdinande, Pascal Reper, Serge Brimioulle, Sophie Van Cromphaut, Stéphane Clement De Clety, Thierry Sottiaux, Pierre Damas
BACKGROUND: In order to decrease the incidence of ventilator-associated pneumonia (VAP) in Belgium, a national campaign for implementing a VAP bundle involving assessment of sedation, cuff pressure control, oral care with chlorhexidine and semirecumbent position, was launched in 2011-2012. This report will document the impact of this campaign. METHODS: On 1 day, once a year from 2010 till 2016, except in 2012, Belgian ICUs were questioned about their ventilated patients...
May 21, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29777295/laser-debulking-or-tracheotomy-in-airway-management-prior-to-total-laryngectomy-for-t4a-laryngeal-cancer
#3
Djamil Semdaie, Fabienne Haroun, Odile Casiraghi, François Bidault, Stéphane Temam, François Janot, Philippe Gorphe
PURPOSE: Retrospective studies have shown that tracheotomy prior to total laryngectomy (TL) is associated with decreased survival. We sought to investigate whether this is due to higher local invasiveness associated with obstructive disease or whether it is the result of tracheotomy itself. METHODS: We reviewed patients with a T4a (AJCC 7th edition) laryngeal squamous-cell carcinoma treated with a primary TL followed by adjuvant radiotherapy between 2001 and 2013...
May 18, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29761077/anatomical-cadaver-study-of-endolaryngeal-vascularization-focus-on-the-glottis-supraglottis-and-subglottis-from-the-transoral-microsurgical-point-of-view
#4
Pietro Perotti, Marco Ferrari, Nausica Montalto, Davide Lancini, Alberto Paderno, Fabiola Incandela, Barbara Buffoli, Luigi Fabrizio Rodella, Cesare Piazza
Introduction: Carbon dioxide laser coagulation during transoral laser microsurgery (TLM) for laryngeal cancer allows control of bleeding from vessels smaller than 0.5 mm. Therefore, larger arteries and veins must be carefully managed by clipping and/or monopolar cautery. The aim of this paper is to detail endolaryngeal vascular anatomy and identify areas of possible bleeding during TLM. Methods: We performed an anatomical study on a series of 11 fresh-frozen human cadavers...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29757551/-expression-and-clinical-significance-of-long-non-coding-rna-linc00520-in-laryngeal-squamous-cell-carcinoma
#5
Yong Yan Wu, Wei Gao, Yu Liang Zhang, Min Niu, Jia Jia Cui, Cai Xia Xiang, Jiang Wei Sang, Shu Xin Wen, Bin Quan Wang
Objective: To investigate the expression of LINC00520 in laryngeal squamous cell carcinoma(LSCC),and analyze its relevance and roles in carcinogenesis and development of LSCC. Method: The expression of LINC00520 in laryngeal squamous cell carcinoma tissue and paired adjacent normal tissue was determined by real-time PCR.The relationship between the expression of LINC00520 and the clinicopathological characteristics including clinical stage,pathological type,histological grade and lymph node metastasis of LSCC was analyzed...
January 20, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29756700/use-of-ultrasonography-as-a-noninvasive-decisive-tool-to-determine-the-accurate-endotracheal-tube-size-in-anesthetized-children
#6
Gulnur Gollu, A Onat Bermede, Farid Khanmammadov, Ufuk Ates, Sinan Genc, Ozlem Selvi Can, Suat Fitoz, Zekeriyya Alanoglu, Aydin Yagmurlu
BACKGROUND: It is hard to determine the appropriate size and correct tracheal position of endotracheal tube (ETT) in children. The aim of this study is to determine tracheal diameter in children by using ultrasonography technique as objective tool and compare it with commonly used aged based formulas for the ETT size estimation. PATIENTS AND METHODS: Patients undergoing elective surgery in a tertiary children's hospital were prospectively enrolled. The subglottic transverse tracheal diameter was determined by ultrasonography...
June 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29756352/outcomes-after-cricotracheal-resection-for-idiopathic-subglottic-stenosis
#7
Patrick S Carpenter, Jenny L Pierce, Marshall E Smith
OBJECTIVES: Idiopathic subglottic stenosis (iSGS) is a rare disease in which patients develop airway narrowing and dyspnea from relapsing subglottic and tracheal granulation and scar tissue that narrows the airway. Definitive management has involved surgical resection and reconstruction of the subglottis and trachea. However, treatment options remain highly variable at different institutions. Here, we present our outcomes and experience after cricotracheal resection (CTR) for iSGS at a high-volume tertiary care center...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29745876/the-presence-of-staphylococcal-superantigens-in-nasal-swabs-and-correlation-with-activity-of-granulomatosis-with-polyangiitis-in-own-material
#8
Justyna Fijołek, Elzbieta Wiatr, Violetta Petroniec, Ewa Augustynowicz-Kopec, Michal Bednarek, Dariusz Gawryluk, Magdalena Maria Martusewicz-Boros, Katarzyna Modrzewska, Elzbieta Radzikowska, Kazimerz Roszkowski-Sliz
OBJECTIVES: Nasal carriage of Staphylococcus aureus and its superantigens (SAg) seem to be a risk factor disease exacerbation in granulomatosis with polyangiitis (GPA). We investigated the association between the presence of SAg in nasal swabs and activity of disease in GPA patients also taking into account correlation with an antimicrobial treatment. METHODS: In a prospective study of a total of 150 GPA patients hospitalised in the period 2009-2016, nasal swabs were examined for the presence of Staphylococcus aureus and SAg...
May 4, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29743805/outcomes-after-endoscopic-dilation-of-laryngotracheal-stenosis-an-analysis-of-acs-nsqip
#9
Avni Bavishi, Emily Boss, Rahul K Shah, Jennifer Lavin
Importance: Endoscopic management of pediatric subglottic stenosis (SGS) is common, however no multi-institutional studies have assessed its perioperative outcomes. The American College of Surgeon's National Surgical Quality Improvement Program - Pediatric (ACS-NSQIP-P) represents a source of such data. Design: Current procedural terminology (CPT) codes were queried for endoscopic or open airway reconstruction in the ACS-NSQIP-P Public Use File (PUF). Demographics and 30-day events were abstracted to compare open to endoscopic techniques and to assess for risk factors for varied outcomes after endoscopic dilation...
March 2018: Journal of Clinical Outcomes Management: JCOM
https://www.readbyqxmd.com/read/29742573/cervical-tracheal-resection-and-anastomosis-for-postintubation-tracheal-stenosis
#10
Muzaffer Kanlikama, Fatih Celenk, Burhanettin Gonuldas, Secaattin Gulsen
In this study the authors evaluated the outcomes of tracheal resection and anastomosis in postintubation tracheal stenosis. The authors also aimed to identify clinical and radiological factors associated with restenosis. Thirty-four consecutive patients were included in the study. Patients with subglottic stenosis who underwent procedures involving cricoid cartilage and patients with other etiologies were excluded from the study. Univariate analysis was performed to determine the risk factors for restenosis...
May 8, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29732908/airway-anomalies-in-patients-with-22q11-2-deletion-syndrome-a-5-year-review
#11
Joel W Jones, Meghan Tracy, Mollie Perryman, Jill M Arganbright
OBJECTIVES: To characterize the frequency of airway anomalies in patients with 22q11.2 deletion syndrome (22q11DS). METHODS: Retrospective review of patients with 22q11DS who had undergone microlaryngoscopy/bronchoscopy (MLB) for aerodigestive symptoms at a tertiary care children's hospital from 2011 to 2016. RESULTS: Thirty patients underwent an MLB due to the following indications: aspiration (11), stridor (10), chronic respiratory failure due to ventilator dependence (8), and difficult intubation (1)...
May 1, 2018: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29728175/congenital-and-iatrogenic-laryngeal-and-vocal-abnormalities-in-patients-with-22q11-2-deletion
#12
Bridget Ebert, James Sidman, Noelle Morrell, Brianne Barnett Roby
BACKGROUND: Voice abnormalities often go unrecognized in patients with 22q11.2 deletion because speech abnormalities become the focus of evaluation. OBJECTIVE: To analyze voice and vocal fold abnormalities in patients with 22q11.2 deletion by examining voice, not speech. METHODS: This is a case series with chart review from 2009 to 2016. Records of both a velocardiofacial syndrome (VCF) clinic and pediatric otolaryngology clinic at a tertiary pediatric hospital were reviewed...
June 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29722877/rituximab-for-induction-and-maintenance-therapy-of-granulomatosis-with-polyangiitis-a-single-centre-cohort-study-on-114-patients
#13
Xavier Puéchal, Michele Iudici, Ana Luisa Calich, Alexandre Vivot, Benjamin Terrier, Alexis Régent, Pascal Cohen, Claire Le Jeunne, Luc Mouthon, Philippe Ravaud, Loïc Guillevin
Objectives: To assess efficacy and safety of rituximab (RTX) induction and maintenance therapy for granulomatosis with polyangiitis (GPA) in a single-centre cohort study. Methods: All patients with active GPA, not enrolled in trials, who received ⩾1 RTX infusion(s) for induction were included. At remission, protocolized maintenance RTX infusions were given every 6 months for 18 months. Kaplan-Meier curves were used to estimate survival rates. Univariable analyses identified factors associated with remission failure and relapse, and Cox models retained independent predictors of relapse...
May 2, 2018: Rheumatology
https://www.readbyqxmd.com/read/29717916/risk-factors-associated-with-the-development-of-acquired-airway-disease-after-congenital-heart-surgery-a-retrospective-cohort-study
#14
Andrew J Matisoff, Pranathi Ari, David Zurakowski, Alexandra G Espinel, Nina Deutsch, Brian K Reilly
OBJECTIVE: In this single-center, retrospective review, we sought to determine the risk factors associated with the development of severe acquired airway disease (AAD; vocal cord paralysis [VCP] or subglottic stenosis [SGS]) in pediatric patients who had undergone surgery for congenital heart disease (CHD) with cardiopulmonary bypass. All patients who required surgical treatment for CHD using cardiopulmonary bypass at our institution between 2010 and 2015 were reviewed. We defined severe AAD as either clinically significant VCP, SGS, or both, requiring consultation with the otolaryngology (ENT) service for evaluation...
April 1, 2018: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29707509/idiopathic-subglottic-stenosis-techniques-and-results
#15
REVIEW
Andrea L Axtell, Douglas J Mathisen
Idiopathic subglottic stenosis is a rare condition of unknown etiology characterized by circumferential stenosis in the subglottic larynx and upper trachea. Historically, patients were treated with dilation or ablation, however this approach has proven to be largely palliative and often leads to recurrence and the need for tracheostomy. A single-staged laryngotracheal resection and reconstruction is now the preferred definitive treatment for idiopathic subglottic stenosis and can be performed with excellent patient outcomes and rare subsequent progression of the disease...
March 2018: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29706817/the-phaces-syndrome-multiple-episodes-of-reproliferation-of-subglottic-hemangioma
#16
Randall W Holdgraf, Melissa Kress
Subglottic hemangioma is a potentially life-threatening manifestation of the PHACES syndrome. The disease process has been treated with corticosteroids, oral chemotherapeutic agents, endoscopic airway interventions, tracheostomy, and even laryngotracheal reconstruction. Oral propranolol has emerged as an effective therapy and in many cases has led to complete regression of hemangioma during the proliferative phase. There have been several reports of patients showing signs of reproliferation after discontinuing propranolol therapy...
April 2018: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/29687184/aerodynamic-findings-and-voice-handicap-index-in-parkinson-s-disease
#17
Sergio Motta, Ugo Cesari, Mariano Paternoster, Giovanni Motta, Giuseppe Orefice
OBJECTIVE: To verify possible relations between vocal disability and aerodynamic measures in selected Parkinson's disease (PD) patients with low/moderate-grade dysphonia. METHODS: Fifteen idiopathic dysphonic PD male patients were examined and compared with 15 euphonic subjects. Testing included the following measures: Voice Handicap Index (VHI), maximum phonation time (MPT), mean estimated subglottal pressure (MESGP), mean sound pressure level (MSPL), mean phonatory power (MPP), mean phonatory efficiency (MPE) and mean phonatory resistance (MPR)...
April 23, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29675058/foreign-body-removal-by-flexible-bronchoscopy-using-retrieval-basket-in-children
#18
Kyunghoon Kim, Hye Jin Lee, Eun Ae Yang, Hwan Soo Kim, Yoon Hong Chun, Jong-Seo Yoon, Hyun Hee Kim, Jin Tack Kim
OBJECTIVES: Aspiration of foreign bodies into the tracheobronchial tree is a common accident in children. This study aimed to evaluate the safety and outcome of foreign body removal by flexible bronchoscopy using a retrieval basket in children. METHODS: This was a retrospective study of children treated for foreign bodies in the airway via flexible bronchoscopy using a retrieval basket at a tertiary hospital in Korea between February 2014 and October 2017. The medical records of the patients were retrospectively reviewed and analyzed...
April 2018: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/29666691/internal-laryngocele-unusual-onset-in-a-91-year-old-female-patient
#19
Maria C Spinosi, Chiara Mezzedimi, Giovanni Monciatti, Desiderio Passali
While internal laryngoceles rarely cause major clinical complaints, they may lead to airway obstruction and require emergency intervention on rare occasions. We report a 91-year-old patient who was referred to the Ear, Nose & Throat Clinic of the Policlinico Santa Maria alle Scotte, Siena, Italy, in 2017 due to recurrent episodes of severe dyspnoea. A flexible nasopharyngolaryngoscopic examination revealed an internal laryngocele of approximately 1.5 cm in diameter that moved up and down the glottic plane, occasionally invading the subglottic space during inspiration and impeding airflow...
February 2018: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29662613/efficacy-of-continuous-versus-intermittent-subglottic-secretion-drainage-in-preventing-ventilator-associated-pneumonia-in-patients-requiring-mechanical-ventilation-a-single-center-randomized-controlled-trial
#20
Hiroko Fujimoto, Osamu Yamaguchi, Hajime Hayami, Mika Shimosaka, Sayaka Tsuboi, Mitsunori Sato, Shigeo Takebayashi, Satoshi Morita, Mari Saito, Takahisa Goto, Kiyoyasu Kurahashi
Objective: Aspiration of subglottic secretion is a widely used intervention to prevent ventilator-associated pneumonia (VAP). This study aimed to compare the efficacy of continuous and intermittent subglottic secretion drainage (SSD) in preventing VAP. Methods: A single-center randomized controlled trial was conducted on adult postoperative patients who were expected to undergo mechanical ventilation for more than 48 hours. Primary outcome measure was incidence of VAP and secondary outcome measures were length of mechanical ventilation and intensive-care unit (ICU) stay...
March 23, 2018: Oncotarget
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