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https://www.readbyqxmd.com/read/28645326/improving-visualization-of-4d-flow-cardiovascular-magnetic-resonance-with-four-dimensional-angiographic-data-generation-of-a-4d-phase-contrast-magnetic-resonance-cardioangiography-4d-pc-mrca
#1
Mariana Bustamante, Vikas Gupta, Carl-Johan Carlhäll, Tino Ebbers
Magnetic Resonance Angiography (MRA) and Phase-Contrast MRA (PC-MRA) approaches used for assessment of cardiovascular morphology typically result in data containing information from the entire cardiac cycle combined into one 2D or 3D image. Information specific to each timeframe of the cardiac cycle is, however, lost in this process. This study proposes a novel technique, called Phase-Contrast Magnetic Resonance CardioAngiography (4D PC-MRCA), that utilizes the full potential of 4D Flow CMR when generating temporally resolved PC-MRA data to improve visualization of the heart and major vessels throughout the cardiac cycle...
June 23, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28645293/prenatal-screening-of-fetal-ventriculoarterial-connections-benefits-of-4d-technique-in-fetal-heart-imaging
#2
Yu Wang, Miao Fan, Faiza Amber Siddiqui, Meilian Wang, Wei Sun, Xue Sun, Wenjia Lei, Ying Zhang
BACKGROUND: Identification of prenatal ventriculoarterial connections in fetuses with conotruncal anomalies (CTA) remains one of the greatest challenges for sonographers performing screening examinations. Herein, we propose a novel protocol of 4D volume analysis that identifies ventriculoarterial connections and evaluate its clinical utility in routine screenings. METHODS: Twenty-nine cases of transposition of the great arteries (TGA), 22 cases of double-outlet right ventricle (DORV), 36 cases of tetralogy of Fallot (TOF), 14 cases of truncus arteriosus (TCA), and randomly selected 70 normal fetuses were reviewed in this study...
June 23, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28640394/in-scan-and-scan-rescan-assessment-of-lv-in-and-outflow-volumes-by-4d-flow-mri-versus-2d-planimetry
#3
Vivian P Kamphuis, Roel L F van der Palen, Patrick J H de Koning, Mohammed S M Elbaz, Rob J van der Geest, Albert de Roos, Arno A W Roest, Jos J M Westenberg
PURPOSE: To evaluate the in-scan and scan-rescan consistency of left ventricular (LV) in- and outflow assessment from 1) 2D planimetry; 2) 4D flow magnetic resonance imaging (MRI) with retrospective valve tracking, and 3) 4D flow MRI with particle tracing. MATERIALS AND METHODS: Ten healthy volunteers (age 27 ± 3 years) underwent multislice cine short-axis planimetry and whole-heart 4D flow MRI on a 3T MRI scanner twice with repositioning between the scans...
June 22, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28637308/three-dimensional-right-ventricular-regional-deformation-and-survival-in-pulmonary-hypertension
#4
Pamela Moceri, Nicolas Duchateau, Delphine Baudouy, Elie-Dan Schouver, Sylvie Leroy, Fabien Squara, Emile Ferrari, Maxime Sermesant
Aims: Survival in pulmonary hypertension (PH) relates to right ventricular (RV) function. However, the RV unique anatomy and structure limit 2D analysis and its regional 3D function has not been studied yet. The aim of this study was to assess the implications of global and regional 3D RV deformation on clinical condition and survival in adults with PH and healthy controls. Methods and results: We collected a prospective longitudinal cohort of 104 consecutive PH patients and 34 healthy controls between September 2014 and December 2015...
June 15, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28624889/transcriptional-control-of-unequal-cleavage-in-early-tubifex-embryos
#5
Momoe Aoki, Takashi Shimizu
Early embryos of the clitellate annelid Tubifex (oligochaete) undergo a series of unequal spiral cell divisions before the descendants of the D quadrant micromeres (cells 2d and 4d) divide bilaterally. Here, we show that inhibition of zygotic transcription by microinjection of α-amanitin (transcription inhibitor) exclusively converts unequal cleavage in cell 2d(11) (granddaughter of 2d) into equal cleavage while other unequal cleavages and ensuing bilateral cleavages in cells 4d and 2d(111) (great-granddaughter of 2d) all proceed in a normal fashion in the presence of this inhibitor...
June 17, 2017: Development Genes and Evolution
https://www.readbyqxmd.com/read/28613163/sinogram-blurring-matrix-estimation-from-point-sources-measurements-with-rank-one-approximation-for-fully-3d-pet
#6
Kuang Gong, Jian Zhou, Michel Tohme, Martin Judenhofer, Yongfeng Yang, Jinyi Qi
An accurate system matrix is essential in PET for reconstructing high quality images. To reduce storage size and image reconstruction time, we factor the system matrix into a product of a geometry projection matrix and a sinogram blurring matrix. The geometric projection matrix is computed analytically and the sinogram blurring matrix is estimated from point source measurements. Previously we have estimated a two dimensional (2D) blurring matrix for a preclinical PET scanner. The 2D blurring matrix only considers blurring effects within a transaxial sinogram and does not compensate for intersinogram blurring effects...
June 2, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28613048/is-the-second-to-fourth-digit-ratio-2d-4d-a-biomarker-of-sex-steroids-activity
#7
Vincenzo de Sanctis, Ashraf T Soliman, Heba Elsedfy, Nada Soliman, Rania Elalaily, Salvatore Di Maio
The second-to-fourth digit ratio (2D:4D) has been used as an indirect method to investigate the putative effects of prenatal exposure to androgens, and has been reported to be smaller in males than in females. This gender difference in digit length ratios has been linked with the in utero balance of androgens to oestrogen. This sexual dimorphism in 2D:4D ratios is apparent by 2 years of age and seems to be established early in life, possibly by the 14th week of gestation. Digits in females attain their maximum length at about 2...
June 2017: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/28585063/enabling-real-time-volume-rendering-of-functional-magnetic-resonance-imaging-on-an-ios-device
#8
Joseph Holub, Eliot Winer
Powerful non-invasive imaging technologies like computed tomography (CT), ultrasound, and magnetic resonance imaging (MRI) are used daily by medical professionals to diagnose and treat patients. While 2D slice viewers have long been the standard, many tools allowing 3D representations of digital medical data are now available. The newest imaging advancement, functional MRI (fMRI) technology, has changed medical imaging from viewing static to dynamic physiology (4D) over time, particularly to study brain activity...
June 5, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28555245/2d-4d-finger-length-ratio-and-skeletal-biomarker-of-biological-aging
#9
Leonid Kalichman, Valery Batsevich, Eugene Kobyliansky
The aim of this population-based study was to evaluate the association between the index to ring (2D:4D) finger length ratio and the osseographic score (OSS), the skeletal biomarker of biological aging. A sample included 802 males and 738 females who had participated in a Chuvashian skeletal aging study. Age, sex, basic demographics, anthropometric data and X-rays of both hands were collected. Each hand was visually classified on X-ray as either Type 1 - index finger was longer than ring finger; Type 2 - equal; or Type 3 - shorter than the ring finger...
May 30, 2017: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
https://www.readbyqxmd.com/read/28553119/potential-role-of-pre-and-postnatal-testosterone-levels-in-attention-deficit-hyperactivity-disorder-is-there-a-sex-difference
#10
Liang-Jen Wang, Miao-Chun Chou, Wen-Jiun Chou, Min-Jing Lee, Sheng-Yu Lee, Pao-Yen Lin, Yi-Hsuan Lee, Yi-Hsin Yang, Cheng-Fang Yen
OBJECTIVE: Both prenatal testosterone (T) exposure and postnatal T levels have been associated with developing neural circuitry and behavioral systems. This study examined the potential correlation between pre- and postnatal T levels and behavioral and neurocognitive profiles of children with attention-deficit/hyperactivity disorder (ADHD). METHODS: Two hundred ADHD patients with a mean age of 8.7±2.0 years (158 boys and 42 girls) were recruited. The ratio of the length of the right index finger (2D) to that of the right ring finger (4D) (2D/4D ratio) served as a surrogate of prenatal T exposure, and postnatal T was determined using salivary T concentration...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28537047/comparison-of-the-ratio-of-the-lenght-of-the-second-and-fourth-digits-in-subgroups-of-fertile-and-infertile-cases
#11
Emre Can Akinsal, Abdullah Demirtas, Oguz Ekmekcioglu
PURPOSE: To identify any relationship between known reasons of male infertility and 2D:4D ratio. MATERIALS AND METHODS: A total of 371 males were included in the study. The cases were grouped into 6 groups including sperm count < 5 million/mL, sperm count ≥ 5 million/mL, Klinefelter Syndrome, hypogonadotropic hypogonadism, vasal agenesis and control. Groups were compared with each other in terms of 2D:4D ratios and groups with a 2D:4D ratios below 1 and equal/above 1 were compared...
May 23, 2017: Urology Journal
https://www.readbyqxmd.com/read/28532524/is-maternal-periconceptional-smoking-associated-with-2d-4d-digit-ratio-in-their-children
#12
M P Velez, T E Arbuckle, P Monnier, W D Fraser
The 2nd--4th finger ratio (2D:4D) has been proposed as a potential indicator of greater androgen exposure during fetal development. Maternal periconceptional smoking may alter the homeostasis of fetal androgens, which could in turn result in differential development of 2D:4Ds in utero. The aim of the present study was to assess the effect of maternal periconceptional smoking (i.e. 1 year before through the first trimester of pregnancy) on the 2D:4D of children within The Maternal-Infant Research on Environmental Chemicals (MIREC) study...
May 23, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28529968/descriptive-statistics-and-regressions-of-2d-4d-and-educational-attainment-based-on-rlms-data
#13
John V C Nye, Maksym Bryukhanov, Sergiy Polyachenko
We document the descriptive statistics and detailed regression outputs for educational attainment and measured 2D:4D ratios, based on the RLMS data (20th round, conducted in 2011-2012). Regression analysis is conducted using STATA 13, gologit2 which is a special code for the generalized ordered logit regression in STATA environment. We provide graphs of differences in means of 2D:4D ratios by educational attainment. Information about the distribution of self-identified nationalities and fields of university degrees of respondents is presented...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28527753/asymmetry-and-empathy-higher-asymmetry-is-associated-with-lower-levels-of-mentalizing
#14
Colton B Christian, Azim F Shariff
People differ in their mentalizing abilities. Though past research suggests that individual differences in exposure to prenatal testosterone may be able to explain why some people excel at mentalizing, while others struggle, meta-analyses yield a null relationship between 2D:4D ratio (a proxy for prenatal testosterone) and mentalizing. Importantly, however, past research has not examined the asymmetrical differences between the digit ratios on the right and left hands. In the current work, we test whether the difference between the digit ratios of the left and right hands may function as a better predictor of mentalizing than digit ratio alone...
May 18, 2017: Early Human Development
https://www.readbyqxmd.com/read/28509846/a-new-ergosterol-analog-a-new-bis-anthraquinone-and-anti-obesity-activity-of-anthraquinones-from-the-marine-sponge-associated-fungus-talaromyces-stipitatus-kufa-0207
#15
Jidapa Noinart, Suradet Buttachon, Tida Dethoup, Luís Gales, José A Pereira, Ralph Urbatzka, Sara Freitas, Michael Lee, Artur M S Silva, Madalena M M Pinto, Vítor Vasconcelos, Anake Kijjoa
A new ergosterol analog, talarosterone (1) and a new bis-anthraquinone derivative (3) were isolated, together with ten known compounds including palmitic acid, ergosta-4,6,8(14),22-tetraen-3-one, ergosterol-5,8-endoperoxide, cyathisterone (2), emodin (4a), questinol (4b), citreorosein (4c), fallacinol (4d), rheoemodin (4e) and secalonic acid A (5), from the ethyl acetate extract of the culture of the marine sponge-associated fungus Talaromyces stipitatus KUFA 0207. The structures of the new compounds were established based on extensive 1D and 2D spectral analysis, and in the case of talarosterone (1), the absolute configurations of its stereogenic carbons were determined by X-ray crystallographic analysis...
May 16, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28504855/relationships-between-digit-ratio-2d-4d-and-basketball-performance-in-australian-men
#16
Nathan A Frick, Melissa J Hull, John T Manning, Grant R Tomkinson
OBJECTIVE: To investigate relationships between the digit ratio (2D:4D) and competitive basketball performance in Australian men. METHODS: Using an observational cross-sectional design a total of 221 Australian basketball players who competed in the Olympic Games, International Basketball Federation World Championships/Cup, Australian National Basketball League, Central Australian Basketball League or socially had their 2D:4Ds measured. Analysis of variance was used to assess differences in mean 2D:4Ds between men playing at different competitive standards, with relationships between 2D:4Ds and basketball game-related statistics assessed using Pearson's product moment correlations in men playing at a single competitive standard...
May 6, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28499134/digit-ratio-2d-4d-and-postoperative-pain-perception
#17
Anna Kasielska-Trojan, Piotr Stabryła, Bogusław Antoszewski
BACKGROUNDS: It has not been established whether sex differences in pain perception are influenced by prenatal sex hormones. Digit ratio as an indicator of prenatal hormone exposure can be used as a simple measure of the influence of prenatal hormones on pain sensitivity or perception in adulthood. OBJECTIVE: The aim of this study was to determine a correlation between the 2D:4D ratio and pain perception in the postoperative period after rhinoplasty. METHOD: A prospective cohort study of 100 patients (50 women of the mean age of 30...
July 2017: Early Human Development
https://www.readbyqxmd.com/read/28499133/value-of-digit-ratio-2d-4d-a-biomarker-of-prenatal-hormone-exposure-is-stable-across-the-menstrual-cycle
#18
Magdalena Klimek, Urszula M Marcinkowska, Grazyna Jasienska
Digit ratio (2D:4D) is used as a marker of prenatal hormone exposure and, consequently, as a predictor of many characteristics throughout a woman's lifespan. A previous study has suggested that values of 2D:4D vary across menstrual cycles and further questioned the reliability of a single measurement of 2D:4D among cycling women, while another study failed to confirm these results. However, these studies estimated the timing of cycle phases based on a date of menstruation reported by participants and also had small sample sizes...
July 2017: Early Human Development
https://www.readbyqxmd.com/read/28497486/5d-whole-heart-sparse-mri
#19
Li Feng, Simone Coppo, Davide Piccini, Jerome Yerly, Ruth P Lim, Pier Giorgio Masci, Matthias Stuber, Daniel K Sodickson, Ricardo Otazo
PURPOSE: A 5D whole-heart sparse imaging framework is proposed for simultaneous assessment of myocardial function and high-resolution cardiac and respiratory motion-resolved whole-heart anatomy in a single continuous noncontrast MR scan. METHODS: A non-electrocardiograph (ECG)-triggered 3D golden-angle radial balanced steady-state free precession sequence was used for data acquisition. The acquired 3D k-space data were sorted into a 5D dataset containing separated cardiac and respiratory dimensions using a self-extracted respiratory motion signal and a recorded ECG signal...
May 11, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28470915/comparison-of-fast-acquisition-strategies-in-whole-heart-four-dimensional-flow-cardiac-mr-two-center-1-5-tesla-phantom-and-in-vivo-validation-study
#20
Pankaj Garg, Jos J M Westenberg, Pieter J van den Boogaard, Peter P Swoboda, Rahoz Aziz, James R J Foley, Graham J Fent, F G J Tyl, L Coratella, Mohammed S M ElBaz, R J van der Geest, David M Higgins, John P Greenwood, Sven Plein
PURPOSE: To validate three widely-used acceleration methods in four-dimensional (4D) flow cardiac MR; segmented 4D-spoiled-gradient-echo (4D-SPGR), 4D-echo-planar-imaging (4D-EPI), and 4D-k-t Broad-use Linear Acquisition Speed-up Technique (4D-k-t BLAST). MATERIALS AND METHODS: Acceleration methods were investigated in static/pulsatile phantoms and 25 volunteers on 1.5 Tesla MR systems. In phantoms, flow was quantified by 2D phase-contrast (PC), the three 4D flow methods and the time-beaker flow measurements...
May 4, 2017: Journal of Magnetic Resonance Imaging: JMRI
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