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HIV cross sectional study

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https://www.readbyqxmd.com/read/28926407/dysfunctional-hdl-from-hiv-individuals-promotes-monocyte-derived-foam-cell-formation-in-vitro
#1
Thomas A Angelovich, Anna C Hearps, Michael N Oda, Mark S Borja, Diana Huynh, Stefanie Homann, Anthony Jaworowski, Theodoros Kelesidis
OBJECTIVE: The role of HDL function in HIV-related atherosclerotic cardiovascular disease (CVD) is unclear. HDLs isolated from HIV+ [HIV(+)HDL] and HIV-uninfected individuals (HDL) were assessed for HDL function and ability to promote monocyte-derived foam cell formation (MDFCF) (a key event in HIV-related CVD) ex vivo. DESIGN/METHODS: Using an established in vitro model of atherogenesis and plasma samples from an established cross-sectional study of virologically-suppressed HIV+ males on stable effective antiretroviral therapy (ART) and with low CVD risk (median age: 42 years; n = 10), we explored the impact of native HDL [HIV(+)HDL] on MDFCF...
September 18, 2017: AIDS
https://www.readbyqxmd.com/read/28926404/metabolic-health-across-the-body-mass-index-spectrum-in-hiv-infected-and-hiv-uninfected-men
#2
Jordan E Lake, Xiuhong Li, Frank J Palella, Kristine M Erlandson, Dorothy Wiley, Lawrence Kingsley, Lisa P Jacobson, Todd T Brown
OBJECTIVES: In the general population, metabolic health (MH) often declines as body mass index (BMI) increases. However, some obese individuals maintain MH. HIV and antiretroviral therapy (ART) have been associated with metabolic disturbances. We hypothesized that HIV-infected (HIV+) men on suppressive ART experience less MH than HIV-uninfected (HIV-) men across all BMI categories. DESIGN/METHODS: In a cross-sectional analysis of 1018 HIV+ and 1092 HIV- men enrolled in the Multicenter AIDS Cohort Study, Poisson regression with robust variance determined associations between HIV serostatus and MH prevalence (defined as meeting 2 of 5 NCEP/ATP III metabolic syndrome criteria), adjusting for age, race, BMI category, smoking and hepatitis C virus infection status...
September 18, 2017: AIDS
https://www.readbyqxmd.com/read/28926398/association-of-a-3-untranslated-region-polymorphism-in-pcsk9-with-hiv-viral-load-and-cd4-levels-in-hiv-hepatitis-c-virus-co-infected-women
#3
Mark H Kuniholm, Hua Liang, Kathryn Anastos, Deborah Gustafson, Seble Kassaye, Marek Nowicki, Beverly E Sha, Emilia J Pawlowski, Stephen J Gange, Bradley E Aouizerat, Tatiana Pushkarsky, Michael I Bukrinsky, Vinayaka R Prasad
OBJECTIVE: To assess variation in genes that regulate cholesterol metabolism in relation to the natural history of HIV infection. DESIGN: Cross-sectional and longitudinal analysis of the Women's Interagency HIV Study (WIHS). METHODS: We examined 2,050 single nucleotide polymorphisms (SNPs) in 19 genes known to regulate cholesterol metabolism in relation to HIV viral load and CD4 T cell levels in a multiracial cohort of 1,066 antiretroviral therapy (ART) naïve women...
September 18, 2017: AIDS
https://www.readbyqxmd.com/read/28924741/spectrum-of-infectious-diseases-among-newly-arrived-eritrean-refugees-in-switzerland-a-cross-sectional-study
#4
Afona Chernet, Andreas Neumayr, Christoph Hatz, Kerstin Kling, Véronique Sydow, Katharina Rentsch, Jürg Utzinger, Nicole Probst-Hensch, Hanspeter Marti, Beatrice Nickel, Niklaus D Labhardt
OBJECTIVES: Our study aimed at determining the prevalence of selected infectious diseases among recently arrived Eritrean refugees in Switzerland. METHODS: In this cross-sectional study, asymptomatic Eritrean migrants aged ≥16 years who arrived <24 months ago were recruited at refugee centres in Switzerland. Infectious disease screening included serology for HIV, hepatitis B and C, syphilis and schistosomiasis, polymerase chain reaction (PCR) for malaria, stool microscopy for helminths and intestinal protozoa and circulating cathodic antigen (CCA) testing in urine for schistosomiasis...
September 19, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28922449/needle-syringe-programmes-and-opioid-substitution-therapy-for-preventing-hepatitis-c-transmission-in-people-who-inject-drugs
#5
REVIEW
Lucy Platt, Silvia Minozzi, Jennifer Reed, Peter Vickerman, Holly Hagan, Clare French, Ashly Jordan, Louisa Degenhardt, Vivian Hope, Sharon Hutchinson, Lisa Maher, Norah Palmateer, Avril Taylor, Julie Bruneau, Matthew Hickman
BACKGROUND: Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugsNeedle syringe programmes (NSP) and opioid substitution therapy (OST) are the primary interventions to reduce hepatitis C (HCV) transmission in people who inject drugs. There is good evidence for the effectiveness of NSP and OST in reducing injecting risk behaviour and increasing evidence for the effectiveness of OST and NSP in reducing HIV acquisition risk, but the evidence on the effectiveness of NSP and OST for preventing HCV acquisition is weak...
September 18, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28919821/prevalence-of-fertility-desire-and-its-associated-factors-among-15-to-49-year-old-people-living-with-hiv-aids-in-addis-ababa-ethiopia-a-cross-sectional-study-design
#6
Takele Menna Adilo, Hirut Megerssa Wordofa
BACKGROUND: The magnitude of unprotected sex to satisfy the desire for fertility among people living with HIV/AIDS (PLHIV) may rise more due to the availability of antiretroviral therapy (ART) in most HIV-affected countries. This could, however, have the risk of passing on HIV to sexual partners and children. The aim of this study, therefore, was to determine the magnitude and factors associated with the fertility desire of reproductive-age PLHIV in Addis Ababa, Ethiopia, for research-based and timely actions...
2017: HIV/AIDS: Research and Palliative Care
https://www.readbyqxmd.com/read/28910924/-a-survey-of-hiv-hbv-and-hcv-infections-in-children-aged-1-13-years-in-yi-ethnic-area-sichuan-province
#7
Y Yang, Y B Zhou, W T Cheng, X Pan, X X Song, Q W Jiang
Objective: To investigate the prevalence of HIV, HBV and HCV infections in children aged 1-13 years in Yi ethnic area in Sichuan province. Methods: A cross-sectional study was conducted in the form of field survey in four townships selected from Yi ethnic area of Sichuan during 2014-2015. Participants were children aged 1-13 years by sample size of 900 and were screened for HIV antibody, HBV surface antigen and HCV antibody, and laboratory comfirmation was conducted. The area, age, gender and ethnic group specific infection rates were compared by using Fisher's exact test, and multiple comparisons were corrected by using Bonferroni correction...
September 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28910308/pulmonary-hypertension-among-5-to-18-year-old-children-with-sickle-cell-anaemia-in-nigeria
#8
Ogochukwu J Sokunbi, Ekanem N Ekure, Edamisan O Temiye, Roosevelt Anyanwu, Christy A N Okoromah
BACKGROUND: Pulmonary hypertension (PHT) is a significant cause of mortality in patients with sickle cell disease (SCD). Few studies on PHT in SCD have been carried out in children. This study aimed to estimate the prevalence of PHT in children with sickle cell anaemia (SCA) and determine its clinical and laboratory correlates. METHODS: In this cross sectional study, evaluation involved obtaining bio-data, history and physical examination findings in 175 SCA subjects with haemoglobin genotype SS aged 5 to 18 years and 175 age and sex matched controls with haemoglobin genotype AA...
2017: PloS One
https://www.readbyqxmd.com/read/28906537/the-changing-spectrum-of-rheumatic-mitral-regurgitation-in-soweto-south-africa
#9
Ruchika Meel, Ferande Peters, Elena Libhaber, Mohammed Rafique Essop
OBJECTIVES: To determine the clinical and echocardiographic characteristics of contemporary patients with rheumatic mitral regurgitation (MR) at Chris Hani Baragwanath Academic Hospital. METHODS: This prospective, cross-sectional study included 84 patients with isolated moderate or severe rheumatic MR who underwent clinical and echocardiographic assessment. RESULTS: Mean age of the patients was 44 ± 15.3 years (84% females). Acute rheumatic fever was rare...
July 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28906351/prevalence-evolution-and-related-risk-factors-of-kidney-disease-among-spanish-hiv-infected-individuals
#10
Javier Juega-Mariño, Anna Bonjoch, Nuria Pérez-Alvarez, Eugenia Negredo, Beatriu Bayes, Josep Bonet, Buenaventura Clotet, Ramon Romero
Prevalence of kidney disease (KD) is increasing among human immunodeficiency virus (HIV)-infected population. Different factors have been related, varying on different published series.The objectives were to study prevalence of KD in those patients, its evolution, and associated risk factors.An observational cohort study of 1596 HIV-positive patients with cross-sectional data collection in 2008 and 2010 was conducted. We obtained clinical and laboratory markers, and registered previous or current treatment with tenofovir (TDF) and indinavir (IDV)...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28905466/adherence-to-pi-based-2-nd-line-regimens-in-cambodia-is-not-simply-a-question-of-individual-behaviour-the-anrs-12276-2picam-study
#11
Luis Sagaon-Teyssier, Bakridine Mmadi Mrenda, Vohith Khol, Laurent Ferradini, Sovatha Mam, Sopheak Ngin, Marion Mora, Gwenaëlle Maradan, Chhi Vun Mean, Olivier Ségéral, Eric Nerrienet, Vonthanak Saphonn, Bruno Spire
OBJECTIVES: To investigate whether adherence to antiretroviral treatment (ART) can be explained not only by individual factors but also by healthcare facilities' characteristics, among a sample of people living with HIV (PLWH) treated with PI-based regimens in Cambodia. METHODS: The ANRS 12276 2PICAM cross-sectional survey was conducted between February 2013 and April 2014 among PLWH followed up in 13 healthcare facilities. The 1316 patients in this analysis corresponded to 90% of the total number of adult patients treated with 2(nd) line PI-based regimens in Cambodia in the study period...
September 14, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28905376/hiv-and-headache-a-cross-sectional-study
#12
Pedro Augusto Sampaio Rocha-Filho, Rinailda Cascia Santos Torres, Ulisses Ramos Montarroyos
INTRODUCTION: The head and neck are the second most common locations for pain among HIV-positive individuals. Most studies were conducted among HIV patients at an advanced stage of the disease. METHODS: This was a cross-sectional study. Patients with HIV and CD4+ T lymphocyte counts >500 were included. Semi-structured interview, the Headache Impact Test (HIT-6), and the Hospital Anxiety and Depression Scale were used. RESULTS: Of the 119 cases included, 63% were men...
September 14, 2017: Headache
https://www.readbyqxmd.com/read/28904698/hiv-related-knowledge-attitude-and-practices-of-healthy-adults-in-cross-river-state-nigeria-a-population-based-survey
#13
Uchenna Okonkwo, Soter Ameh, Akaninyene Otu, Henry Okpara
INTRODUCTION: Human Immunodeficiency Virus (HIV) remains a global health problem disproportionately distributed across Nigeria. Cross river state (CRS), a tourist state, located in the Niger delta, has one of the highest prevalence rates. There is evidence that poor knowledge and stigmatization are obstacles to achieving universal access to HIV prevention programs. The objective of this study was to determine the Knowledge, Attitude and Practice (KAP) of HIV among adults resident in CRS, Nigeria...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28902678/brief-report-high-need-to-switch-cart-or-comedication-with-the-initiation-of-daas-in-elderly-hiv-hcv-coinfected-patients
#14
Elise J Smolders, Colette Smit, Clara T M M de Kanter, Anton S M Dofferiiof, Joop E Arends, Kees Brinkman, Bart Rijnders, Marc van der Valk, Peter Reiss, David M Burger
BACKGROUND: To describe the use of nonantiretroviral comedication and combination antiretroviral therapy (cART) in patients coinfected with HIV/hepatitis C virus (HCV) and to predict the potential for drug-drug interactions (DDIs) with direct-acting antivirals (DAAs) against HCV. METHODS: This is a retrospective, cross-sectional study, using the Dutch, nationwide ATHENA observational HIV cohort database. All patients with a known HIV/HCV coinfection on January 1, 2015, were included...
October 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28895288/association-between-hiv-and-blood-pressure-in-adults-and-role-of-body-weight-as-a-mediator-cross-sectional-study-in-uganda
#15
Samson Okello, Peter Ueda, Michael Kanyesigye, Emmanuel Byaruhanga, Achilles Kiyimba, Gideon Amanyire, Alex Kintu, Wafaie W Fawzi, Winnie R Muyindike, Goodarz Danaei
The authors sought to describe the association between human immunodeficiency virus (HIV) and blood pressure (BP) levels, and determined the extent to which this relationship is mediated by body weight in a cross-sectional study of HIV-infected and HIV-uninfected controls matched by age, sex, and neighborhood. Mixed-effects models were fit to determine the association between HIV and BP and amount of effect of HIV on BP mediated through body mass index. Data were analyzed from 577 HIV-infected and 538 matched HIV-uninfected participants...
September 12, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28893749/cross-sectional-comparative-study-of-risky-sexual-behaviours-among-hiv-infected-persons-initiated-and-waiting-to-start-antiretroviral-therapy-in-rural-rakai-uganda
#16
Lydia Jacenta Nakiganda, Gertrude Nakigozi, Joseph Kagaayi, Fred Nalugoda, David Serwadda, Nelson Sewankambo, Ronald Gray, Anthony Ndyanabo, Richard Muwanika, Benedict Oppong Asamoah
OBJECTIVES: To compare risky sexual behaviours between HIV-positive persons initiated on antiretroviral therapy (ART) (ART-experienced) and persons waiting to start on ART (ART-naive) and assess predictors of risky sexual behaviours among HIV-infected patients in rural Rakai district, Uganda. STUDY DESIGN: This is a cross-sectional study that used data from the Rakai Community Cohort Study (RCCS) database between 2013 and 2014. A structured questionnaire was used for data collection...
September 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28893207/hepatitis-b-virus-and-hiv-co-infection-among-pregnant-women-in-rwanda
#17
Mwumvaneza Mutagoma, Helene Balisanga, Samuel S Malamba, Dieudonné Sebuhoro, Eric Remera, David J Riedel, Steve Kanters, Sabin Nsanzimana
BACKGROUND: Hepatitis B virus (HBV) affects people worldwide but the local burden especially in pregnant women and their new born babies is unknown. In Rwanda HIV-infected individuals who are also infected with HBV are supposed to be initiated on ART immediately. HBV is easily transmitted from mother to child during delivery. We sought to estimate the prevalence of chronic HBV infection among pregnant women attending ante-natal clinic (ANC) in Rwanda and to determine factors associated with HBV and HIV co-infection...
September 11, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28893193/light-emitting-diode-fluorescent-microscopy-and-xpert-mtb-rif%C3%A2-assay-for-diagnosis-of-pulmonary-tuberculosis-among-patients-attending-ambo-hospital-west-central-ethiopia
#18
Alemu Gadissa Gelalcha, Abebaw Kebede, Hassen Mamo
BACKGROUND: The relatively simple and cheaper light-emitting diode fluorescent microscopy (LED-FM) was recommended by the World Health Organization (WHO) to replace the conventional tuberculosis (TB) microscopy in both high- and low-volume laboratories. More recently the WHO also endorsed one more technique, Xpert MTB/RIF® assay (Xpert), for improved TB diagnosis particularly among human immunodeficiency virus (HIV)-infected cases. However, the relative performance of both of these tools differs from setting to setting in reference to the conventional TB diagnostics...
September 11, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28892896/detection-of-cytomegalovirus-in-bronchoalveolar-lavage-fluid-from-hiv-positive-individuals-with-community-acquired-pneumonia
#19
Arati Mane, Pankaj Gujar, Shraddha Gaikwad, Tilak Dhamgaye, Arun Risbud
INTRODUCTION: Cytomegalovirus (CMV) pneumonia is one of the frequent viral pneumonia reported in persons with HIV infection. Knowledge of pulmonary CMV infection is important for deciding appropriate diagnostic strategies. However, there is scanty literature addressing the role of CMV aetiology among HIV positive individuals presenting with Community Acquired Pneumonia (CAP) using Bronchoalveolar Lavage (BAL) samples from India. AIM: To detect CMV in BAL fluid from HIV-positive individuals presenting with CAP...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28891536/urine-osmolality-in-treatment-na%C3%A3-ve-hiv-positive-subjects-in-southeast-nigeria
#20
E N Anyabolu, I I Chukwuonye, I Ezeani
BACKGROUND AND OBJECTIVES: Urine osmolality varies over a wide range of values in a healthy state. Dilute urine or concentrated urine may be observed in many environmental, physiologic, and disease conditions. Urine osmolality is not commonly evaluated in routine clinical practice and in human immunodeficiency virus (HIV) subjects. The factors that influence urine osmolality have not been completely identified. The aim of this study was to evaluate urine osmolality in treatment-naïve HIV subjects and to identify the factors that may influence dilute and concentrated urine in this group of patients...
August 2017: Nigerian Journal of Clinical Practice
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