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Cerebral Contusion

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https://www.readbyqxmd.com/read/29774196/common-carotid-artery-dissection-in-multiple-extracranial-injury-a-case-report
#1
Jin Sang Kil, Mi Kyung Lee, Ki Seong Eom
Traumatic common carotid artery dissection (CCAD) is rare. To our knowledge, only 14 case reports have described traumatic CCAD previously. Here, we report a case of CCAD in a patient with severe trauma. A 50-year-old man was lying on the road after drinking alcohol when a car drove over him. Computed tomography (CT) revealed multiple rib fractures with hemopneumothorax, lung contusion, flail chest, large amount of hematoma with bladder rupture, and fractures on the C6 spinous process, sacral ala, iliac bone, and pubic ramus...
April 2018: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/29773781/clinicopathological-characteristics-of-traumatic-head-injury-in-juvenile-middle-aged-and-elderly-individuals
#2
Jiawen Wang, Feng Han, Qian Zhao, Bin Xia, Jialin Dai, Qian Wang, Shimei Huang, Cuiyun Le, Zhu Li, Jiangjin Liu, Ming Yang, Changwu Wan, Jie Wang
BACKGROUND Traumatic head injury is a leading cause of death and disability worldwide. How clinicopathological features differ by age remains unclear. This epidemiological study analyzed the clinicopathological features of patients with head injury belonging to 3 age groups. MATERIAL AND METHODS Data of patients with traumatic head injury were obtained from the Department of Cerebral Surgery of the Affiliated Hospital of Guizhou Medical University and the Guizhou Provincial People's Hospital in 2011-2015. Their clinicopathological parameters were assessed...
May 18, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29768967/interleukin-1-receptor-1-deletion-in-focal-and-diffuse-experimental-traumatic-brain-injury-in-mice
#3
Joon Yong Chung, Nicolas Krapp, Limin Wu, Sevda Lule, Lauren McAllister, William Edmiston Iii, Samantha Martin, Emily Levy, Tanya Songtachalert, John Sherwood, Erin Buckley, Bharat Sanders, Saef Izzy, Suzanne Hickman, Shuzhen Guo, Josephine Lok, Joseph El Khoury, Eng Lo, David Kaplan, Michael Whalen
Important differences in the biology of focal and diffuse traumatic brain injury (TBI) subtypes may result in unique pathophysiological responses to shared molecular mechanisms. Interleukin-1 (IL-1) signaling has been tested as a potential therapeutic target in preclinical models of cerebral contusion and diffuse TBI, and in a phase II clinical trial, but no published studies have examined IL-1 signaling in an impact/acceleration closed head injury (CHI) model. We hypothesized that genetic deletion of IL-1 receptor-1 (IL-1R1 KO) would be beneficial in focal (contusion) and CHI in mice...
May 17, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29758367/clinical-and-neurosurgical-management-of-cranial-machete-injuries-the-experience-of-a-tertiary-referral-center-in-nicaragua
#4
Luis Zapata, Ernest J Wright, Peter Nakaji
BACKGROUND: The neurosurgical literature rarely describes managing open head injuries caused by machetes, although this is a common head injury in developing countries. We present our experience managing cranial machete injuries in Nicaragua over a 5-year period. METHODS: A retrospective chart review identified patients admitted to a neurosurgery service for cranial machete injury. RESULTS: Among 51 patients studied, the majority (n=42, 82%) presented with mild neurological deficits (Glasgow Coma Scale score ≥14)...
May 11, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29694653/clinical-factors-predictive-of-traumatic-brain-injuries-in-case-of-mild-traumatic-brain-injury-in-children-case-control-study
#5
Widad Gueddari, Amine Ouardi, Sanaa Talbi, Sihem Salam, Abdelhadi Zineddine
BACKGROUND: Mild head injury (MHI) is very common in children and the problem is a lack of consensus criteria for the indication of a brain CT. OBJECTIVE: To determine predictors of cranio-cerebral lesions (CCL) in the case of MHI in children. METHODS: Case-control study over a period of 3 years. Included children aged 1 month to 15 years, were those admitted to the department of Pediatric Emergencies for MHI and had performed a brain CT. The principal outcome was the presence of traumatic brain injury...
July 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29682032/analysis-of-factors-influencing-outcome-of-depressed-fracture-of-skull
#6
Ritesh S Satardey, Srikant Balasubramaniam, Jayashree S Pandya, Rajesh C Mahey
Context: The outcome of patients with depressed fracture varies and depends on multiple factors. There has been no previous study on the significance of these factors on the outcome of depressed fracture of the skull and hence this study. Aims: The primary aim of our study is to find the factors affecting the outcome in cases of depressed skull fracture (DSF). This will help us improve outcomes and give more accurate prediction of long-term outcomes. Settings and Design: Prospective observational study...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29672696/infant-abuse-diagnosis-associated-with-abusive-head-trauma-criteria-incidence-increase-due-to-overdiagnosis
#7
Ulf Högberg, Erik Lampa, Göran Högberg, Peter Aspelin, Fredrik Serenius, Ingemar Thiblin
Background: The hypothesis of this study is that the diagnosis of infant abuse is associated with criteria for shaken baby syndrome (SBS)/abusive head trauma (AHT), and that that changes in incidence of abuse diagnosis in infants may be due to increased awareness of SBS/AHT criteria. Methods: This was a population-based register study. Setting: Register study using the Swedish Patient Register, Medical Birth Register, and Cause of Death Register. The diagnosis of infant abuse was based on the International Classification of Diseases, 9th and 10th revision...
April 17, 2018: European Journal of Public Health
https://www.readbyqxmd.com/read/29620180/a-study-on-the-correlation-between-stat%C3%A2-1-and-mutant-p53-expression-in-glioma
#8
Wenbo Yang, Hongwei Wang, Haitao Ju, Changwu Dou
Glioma is the most common primary brain tumor in adults and the second most common malignant tumor in children. Aberrant expression of signal transducer and activator of transcription 1 (STAT‑1) and p53 are known to affect the occurrence and progression of malignant tumors. The aim of the present study was to investigate the expression of STAT‑1 and mutant p53 gene, as well as their correlation, in patients with glioma. The present study included 50 patients who underwent glioma resection at the First Affiliated Hospital of Inner Mongolia Medical University between December 2007 and December 2011, and 10 patients with acute cerebral contusion who underwent intracerebral hematoma removal at the same hospital between January 2013 and January 2014...
March 28, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29594463/traumatic-brain-injury-in-indian-children
#9
REVIEW
Krishna Chaitanya, Archana Addanki, Rajendra Karambelkar, Rakesh Ranjan
INTRODUCTION: Traumatic brain injury (TBI) in children and adolescents is a community-based medical and educational challenge world-over due to increasing urbanization and motorization. In India, children between 1 to 15 years constitute significant proportion of the total population, who are vulnerable for TBI. In developed countries, pediatric trauma mortality still represents more than half of all childhood fatalities, which is 18 times more common than brain tumors. In this study, we attempted to analyze epidemiological factors, management, and outcome of TBI in children at a tertiary care center in Pune, Maharashtra...
March 29, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29588245/predicting-dural-tear-in-compound-depressed-skull-fractures-a-prospective-multi-center-correlational-study
#10
Shemsedin Musefa Salia, Hagos Biluts Mersha, Abenezer Tirsit Aklilu, Abate Sahlu Baleh, Morten Lund-Johansen
BACKGROUND: Compound depressed skull fractures (DSF) are neurosurgical emergencies. Pre-operative knowledge of dural status is indispensable for treatment decision. This study aims to determine predictors of dural tear from clinical and imaging characteristics in patients with compound DSF. PATIENTS AND METHODS: The authors conducted a prospective, multi-center correlational study in neurosurgical hospitals in Addis Ababa, Ethiopia. Patients (n=128) operated from January 1 to October 31, 2016 were included...
March 24, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29574629/exercise-rehabilitation-attenuates-cognitive-deficits-in-rats-with-traumatic-brain-injury-by-stimulating-the-cerebral-hsp20-bdnf-trkb-signalling-axis
#11
Willy Chou, Yu-Fan Liu, Cheng-Hsien Lin, Mao-Tsun Lin, Chi-Chun Chen, Wen-Pin Liu, Ching-Ping Chang, Chung-Ching Chio
Physical exercise (PE) is an effective method for improving cognitive function among patients with traumatic brain injury (TBI). We previously demonstrated that PE with an infrared-sensing running wheel (ISRW) system provides strong neuroprotection in an experimental animal model of stroke. In this study, we used fluid percussion injury in rats to simulate mild TBI. For rats, we used both passive avoidance learning and the Y-maze tests to evaluate cognitive function. We investigated whether PE rehabilitation attenuated cognitive deficits in rats with TBI and determined the contribution of hippocampal and cortical expression of heat shock protein 20 (HSP20) to PE-mediated cognitive recovery...
March 25, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29520416/assessment-of-sensitivity-of-whole-body-ct-for-major-trauma
#12
Susan Yoong, Ravi Kothari, Adam Brooks
INTRODUCTION: Whole body computed tomography has become standard practice in many centres in the management of severely injured trauma patients, however, the evidence for it's diagnostic accuracy is limited. AIM: To assess the sensitivity of whole body CT in major trauma. METHOD: Retrospective review of all patients with injury severity score (ISS) > 15 presenting with blunt trauma to a UK Major Trauma Centre between May 2012 and April 2014...
March 8, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29515418/a-case-of-traumatic-brain-injury-presenting-with-musical-hallucinations
#13
Yasutaka Kobayashi
A 67-year-old woman was hospitalized for rehabilitation from the after effects of a traumatic brain injury. In addition to memory impairment, attention disorder, and executive dysfunction, she experienced musical hallucinations. Brain magnetic resonance imaging revealed cerebral contusion in the bilateral temporal lobes and the left frontal lobe. Case reports of musical hallucinations caused by traumatic brain injury are extremely rare.
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29495544/impact-of-sexual-dimorphism-on-trauma-patterns-and-clinical-outcomes-of-patients-with-a-high-risk-score-of-the-osteoporosis-self-assessment-tool-for-asians-a-propensity-score-matched-analysis
#14
Chien-En Tang, Hang-Tsung Liu, Pao-Jen Kuo, Yi-Chun Chen, Shiun-Yuan Hsu, Chih-Che Lin, Ching-Hua Hsieh
The Osteoporosis Self-assessment Tool for Asians (OSTA) is a validated index based on age and weight to predict the risk of osteoporosis in women. This cross-sectional study was designed to evaluate the impact of sexual dimorphism on the trauma patterns and the clinical outcomes of patients with high-risk OSTA scores. Trauma data of patients with high-risk OSTA scores between 1 January 2009 and 31 December 2015 were retrieved from the trauma registry system of a level I trauma center. A total of 2248 patients including 1585 women and 663 men were included in this study...
February 27, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29492116/cerebral-contusion-an-investigation-of-etiology-risk-factors-related-diagnoses-and-the-surgical-management-at-a-major-government-hospital-in-cambodia
#15
Louise Vera Hilmer, Kee Bum Park, Iv Vycheth, Michael Wirsching
Introduction: Cerebral contusions are a common type of injury among the Cambodian population, mostly due to road traffic accidents. This article aims to assess various aspects around brain contusion focusing on the condition at admission, residing province, mechanism and time of injury, age and sex distribution with differing helmet wearing, and alcohol consumption patterns. Hospitalization-related data such as treatment and outcome were analyzed. Methods: This was a retrospective analysis of 406 cases who have been admitted during the period between May 2013 and May 2016...
January 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29471249/post-mortem-biochemistry-of-nse-and-s100b-a-supplemental-tool-for-detecting-a-lethal-traumatic-brain-injury
#16
Monique Sieber, Jan Dreßler, Heike Franke, Dirk Pohlers, Benjamin Ondruschka
PURPOSE: Traumatic brain injury (TBI) is a very common entity that leads to numerous fatalities all over the world. Therefore, forensic pathologists are in desperate need of supplemental methodological tools for the diagnosis of TBI in everyday practice besides the standard autopsy. The present study determined post-mortem neuron specific enolase (NSE) and S100 calcium-binding protein B (S100B) levels as biological markers of an underlying TBI in autopsy cases. METHODS: Paired serum and CSF samples of 92 fatalities were collected throughout routine autopsies...
April 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29464700/septic-cavernous-sinus-thrombosis-following-a-minor-head-injury-a-rare-cause-of-medico-legal-death
#17
Supawon Srettabunjong
Septic cavernous sinus thrombosis (SCST) is an uncommon consequence of head and face infection, but a rare complication after craniofacial fracture. In this case, SCST developed in a 13-year-old girl following a minor fall during volleyball, with impact and resulting abrasive contusion of the left forehead. She developed watery rhinorrhea, progressive headache, fever, nausea, vomiting, and left proptosis with blurred vision, and was admitted to hospital 3 days after injury. Drowsiness, high-grade fever, severe headache, left ocular pain with marked periorbital swelling, and paralysis of extraocular eye movements developed...
February 21, 2018: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29439124/dual-energy-ct-in-hemorrhagic-progression-of-cerebral-contusion-overestimation-of-hematoma-volumes-on-standard-120-kv-images-and-rectification-with-virtual-high-energy-monochromatic-images-after-contrast-enhanced-whole-body-imaging
#18
U K Bodanapally, K Shanmuganathan, G Issa, D Dreizin, G Li, K Sudini, T R Fleiter
BACKGROUND AND PURPOSE: In patients with hemorrhagic contusions, hematoma volumes are overestimated on follow-up standard 120-kV images obtained after contrast-enhanced whole-body CT. We aimed to retrospectively determine hemorrhagic progression of contusion rates on 120-kV and 190-keV images derived from dual-energy CT and the magnitude of hematoma volume overestimation. MATERIALS AND METHODS: We retrospectively analyzed admission and follow-up CT studies in 40 patients with hemorrhagic contusions...
April 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29425056/human-brain-trauma-severity-is-associated-with-lectin-complement-pathway-activation
#19
Daiana De Blasio, Stefano Fumagalli, Franca Orsini, Laura Neglia, Carlo Perego, Fabrizio Ortolano, Elisa R Zanier, Edoardo Picetti, Marco Locatelli, Nino Stocchetti, Luca Longhi, Peter Garred, Maria-Grazia De Simoni
We explored the involvement of the lectin pathway of complement in post-traumatic brain injury (TBI) pathophysiology in humans. Brain samples were obtained from 28 patients who had undergone therapeutic contusion removal, within 12 h (early) or from >12 h until five days (late) from injury, and from five non-TBI patients. Imaging analysis indicated that lectin pathway initiator molecules (MBL, ficolin-1, ficolin-2 and ficolin-3), the key enzymes MASP-2 and MASP-3, and the downstream complement components (C3 fragments and TCC) were present inside and outside brain vessels in all contusions...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29401110/autopsy-case-of-a-penetrating-wound-to-the-left-cerebral-hemisphere-caused-by-an-accidental-shooting-with-a-crossbow
#20
Takeshi Kondo, Motonori Takahashi, Azumi Kuse, Mai Morichika, Kanako Nakagawa, Yoshihiro Tagawa, Tomoya Taniguchi, Yuji Taguchi, Tomohiro Fujiwara, Junpei Tsuchiya, Masahiko Nakamura, Makoto Sakurada, Migiwa Asano, Yasuhiro Ueno
A crossbow is a bow that shoots an arrow when a gun-like trigger is pulled. Deaths caused by accidental crossbow shootings are extremely rare. Here we describe an autopsy case of a penetrating wound to the left cerebral hemisphere caused by an accidental shooting with a crossbow. A man in his early 60s who lived with his wife and had used crossbows for 20 years as his hobby was found one early morning in the shed of his house, collapsed and bleeding from the head and neck. He was taken to a hospital and died after approximately 3 days of conservative treatment...
February 2, 2018: American Journal of Forensic Medicine and Pathology
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