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https://www.readbyqxmd.com/read/28203210/auditory-and-visual-electrophysiology-of-deaf-children-with-cochlear-implants-implications-for-cross-modal-plasticity
#1
David P Corina, Shane Blau, Todd LaMarr, Laurel A Lawyer, Sharon Coffey-Corina
Deaf children who receive a cochlear implant early in life and engage in intensive oral/aural therapy often make great strides in spoken language acquisition. However, despite clinicians' best efforts, there is a great deal of variability in language outcomes. One concern is that cortical regions which normally support auditory processing may become reorganized for visual function, leaving fewer available resources for auditory language acquisition. The conditions under which these changes occur are not well understood, but we may begin investigating this phenomenon by looking for interactions between auditory and visual evoked cortical potentials in deaf children...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28195673/ultrasound-enhanced-sirna-delivery-using-magnetic-nanoparticle-loaded-chitosan-deoxycholic-acid-nanodroplets
#2
Jeong Yu Lee, Calum Crake, Boon Teo, Dario Carugo, Marie de Saint Victor, Anjali Seth, Eleanor Stride
Small interfering RNA (siRNA) has significant therapeutic potential but its clinical translation has been severely inhibited by a lack of effective delivery strategies. Previous work has demonstrated that perfluorocarbon nanodroplets loaded with magnetic nanoparticles can facilitate the intracellular delivery of a conventional chemotherapeutic drug. The aim of this study is to determine whether a similar agent can provide a means of delivering siRNA, enabling efficient transfection without degradation of the molecule...
February 13, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28188327/tactile-stimuli-affect-long-range-correlations-of-stride-interval-and-stride-length-differently-during-walking
#3
Jung Hung Chien, V N Pradeep Ambati, Chun-Kai Huang, Mukul Mukherjee
Sensory feedback below the sole of the foot using sub-threshold mechanical noise significantly reduced postural sway in patients with diabetes and stroke. However, the effects of tactile parameters on walking are still elusive. Specifically, the effects of such parameters on human gait variability need to be studied because of possible rehabilitation outcomes in terms of bringing improvement in temporal and spatial gait parameters. The purpose of this study was to investigate whether different frequency and amplitude combinations of vibro-tactile stimulation of feet would affect stride-to-stride variability in healthy young adults...
February 10, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28184193/altered-functional-performance-in-patients-with-fibromyalgia
#4
Isis da Silva Costa, Antoni Gamundí, José G Vivas Miranda, Lucas G Souza França, Charles Novaes De Santana, Pedro Montoya
Fibromyalgia is a common chronic pain condition that exerts a considerable impact on patients' daily activities and quality of life. Objectives: The main objective of the present study was to evaluate kinematic parameters of gait, functional performance, and balance in women with fibromyalgia syndrome. Methods: The study included 26 female patients with fibromyalgia (49.2 ± 8.0 years) according to the criteria of the American College of Rheumatology, as well as 16 pain-free women (43.5 ± 8.5 years). Gait and balance parameters were extracted from video recordings of participants performing several motor tasks...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28149367/triathlon-wetsuit-removal-strategy-physiological-cost-of-running-with-a-wetsuit
#5
Mihaela Ciulei, Aaron Prado, James Navalta, John A Mercer
Triathletes exiting the swim portion of an event have to decide on how and when to take a wetsuit off (if worn). The purpose of this study was to determine the physiological cost of running while not using a wetsuit, carrying a wetsuit, wearing a wetsuit halfway down or wearing a wetsuit fully up. Participants (n = 20, 30.9 ± 8.7 yrs, 1.71 ± 0.08 m, 71.6 ± 9.5 kg) completed four 5 min running conditions: 1) not wearing the wetsuit, 2) wearing the wetsuit fully up, 3) wearing the wetsuit halfway down, and 4) carrying the wetsuit...
June 1, 2016: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28143497/gait-disorders-in-the-elderly-and-dual-task-gait-analysis-a-new-approach-for-identifying-motor-phenotypes
#6
Bernard Auvinet, Claude Touzard, François Montestruc, Arnaud Delafond, Vincent Goeb
BACKGROUND: Gait disorders and gait analysis under single and dual-task conditions are topics of great interest, but very few studies have looked for the relevance of gait analysis under dual-task conditions in elderly people on the basis of a clinical approach. METHODS: An observational study including 103 patients (mean age 76.3 ± 7.2, women 56%) suffering from gait disorders or memory impairment was conducted. Gait analysis under dual-task conditions was carried out for all patients...
January 31, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28113592/visuomotor-entrainment-and-the-frequency-dependent-response-of-walking-balance-to-perturbations
#7
Jason R Franz, Carrie Francis, Matt Allen, Darryl G Thelen
Visuomotor entrainment, or the synchronization of motor responses to visual stimuli, is a naturally emergent phenomenon in human standing. Our purpose was to investigate the prevalence and resolution of visuomotor entrainment in walking and the frequency-dependent response of walking balance to perturbations. We used a virtual reality environment to manipulate optical flow in ten healthy young adults during treadmill walking. A motion capture system recorded trunk, sacrum, and heel marker trajectories during a series of 3-min conditions in which we perturbed a virtual hallway mediolaterally with systematic changes in the driving frequencies of perceived motion...
August 26, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28104752/reduced-prosthetic-stiffness-lowers-the-metabolic-cost-of-running-for-athletes-with-bilateral-transtibial-amputations
#8
Owen N Beck, Paolo Taboga, Alena Marie Grabowski
Inspired by the spring-like action of biological legs, running-specific prostheses are designed to enable athletes with lower-limb amputations to run. Yet, manufacturer recommendations for prosthetic stiffness and height may not optimize running performance. Therefore, we investigated the effects of using different prosthetic configurations on the metabolic cost and biomechanics of running. Five athletes with bilateral transtibial amputations each performed fifteen trials on a force-measuring treadmill at 2...
January 19, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28099517/walking-on-a-vertically-oscillating-treadmill-phase-synchronization-and-gait-kinematics
#9
Jeff A Nessler, Severne Heredia, Jacques Bélair, John Milton
Sensory motor synchronization can be used to alter gait behavior. This type of therapy may be useful in a rehabilitative setting, though several questions remain regarding the most effective way to promote and sustain synchronization. The purpose of this study was to describe a new technique for using synchronization to influence a person's gait and to compare walking behavior under this paradigm with that of side by side walking. Thirty one subjects walked on a motorized treadmill that was placed on a platform that oscillated vertically at various frequencies and amplitudes...
2017: PloS One
https://www.readbyqxmd.com/read/28076413/dynamic-characteristics-of-ventilatory-and-gas-exchange-during-sinusoidal-walking-in-humans
#10
Yoshiyuki Fukuoka, Masaaki Iihoshi, Juhelee Tuba Nazunin, Daijiro Abe, Yoshiyuki Fukuba
Our present study investigated whether the ventilatory and gas exchange responses show different dynamics in response to sinusoidal change in cycle work rate or walking speed even if the metabolic demand was equivalent in both types of exercise. Locomotive parameters (stride length and step frequency), breath-by-breath ventilation (V̇E) and gas exchange (CO2 output (V̇CO2) and O2 uptake (V̇O2)) responses were measured in 10 healthy young participants. The speed of the treadmill was sinusoidally changed between 3 km·h-1 and 6 km·h-1 with various periods (from 10 to 1 min)...
2017: PloS One
https://www.readbyqxmd.com/read/28065472/adaptive-changes-in-running-kinematics-as-a-function-of-head-stability-demands-and-their-effect-on-shock-transmission
#11
Jongil Lim, Michael A Busa, Richard E A van Emmerik, Joseph Hamill
This study aimed to identify adaptive changes in running kinematics and impact shock transmission as a function of head stability requirements. Fifteen strides from twelve recreational runners were collected during preferred speed treadmill running. Head stability demands were manipulated through real-time visual feedback that required head-gaze orientation to maintain within boxes of different sizes, ranging from 21° to 3° of visual angle with 3° decrements. The main outcome measures were tibial and head peak accelerations in the time and frequency domains (impact and active phases), shock transmission from tibia to head, stride parameters, and sagittal plane joint kinematics...
December 29, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27973615/soluble-milk-protein-supplementation-with-moderate-physical-activity-improves-locomotion-function-in-aging-rats
#12
Aude Lafoux, Charlotte Baudry, Cécile Bonhomme, Pascale Le Ruyet, Corinne Huchet
Aging is associated with a loss of muscle mass and functional capacity. Present study was designed to compare the impact of specific dairy proteins on muscular function with or without a low-intensity physical activity program on a treadmill in an aged rat model. We investigated the effects of nutritional supplementation, five days a week over a 2-month period with a slow digestible protein, casein or fast digestible proteins, whey or soluble milk protein, on strength and locomotor parameters in sedentary or active aged Wistar RjHan rats (17-19 months of age)...
2016: PloS One
https://www.readbyqxmd.com/read/27932975/adaptations-of-prefrontal-brain-activity-executive-functions-and-gait-in-healthy-elderly-following-exergame-and-balance-training-a-randomized-controlled-study
#13
Alexandra Schättin, Rendel Arner, Federico Gennaro, Eling D de Bruin
During aging, the prefrontal cortex (PFC) undergoes age-dependent neuronal changes influencing cognitive and motor functions. Motor-learning interventions are hypothesized to ameliorate motor and cognitive deficits in older adults. Especially, video game-based physical exercise might have the potential to train motor in combination with cognitive abilities in older adults. The aim of this study was to compare conventional balance training with video game-based physical exercise, a so-called exergame, on the relative power (RP) of electroencephalographic (EEG) frequencies over the PFC, executive function (EF), and gait performance...
2016: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/27908016/bistable-gaits-and-wobbling-induced-by-pedestrian-bridge-interactions
#14
Igor V Belykh, Russell Jeter, Vladimir N Belykh
Several modern footbridges around the world have experienced large lateral vibrations during crowd loading events. The onset of large-amplitude bridge wobbling has generally been attributed to crowd synchrony; although, its role in the initiation of wobbling has been challenged. To study the contribution of a single pedestrian into overall, possibly unsynchronized, crowd dynamics, we use a bio-mechanically inspired inverted pendulum model of human balance and analyze its bi-directional interaction with a lively bridge...
November 2016: Chaos
https://www.readbyqxmd.com/read/27852765/light-level-impacts-locomotor-biomechanics-in-a-secondarily-diurnal-gecko-rhoptropus-afer
#15
Aleksandra V Birn-Jeffery, Timothy E Higham
Locomotion through complex habitats relies on the continuous feedback from a number of sensory systems, including vision. Animals face a visual trade-off between acuity and light sensitivity that depends on light levels, which will dramatically impact the ability to process information and move quickly through a habitat, making ambient illumination an incredibly important ecological factor. Despite this, there is a paucity of data examining ambient light in the context of locomotor dynamics. There have been several independent transitions from the nocturnal ancestor to a diurnal activity pattern among geckos...
November 15, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27825072/surface-emg-analysis-for-the-quantification-of-thigh-muscle-dynamic-co-contractions-during-normal-gait
#16
Annachiara Strazza, Alessandro Mengarelli, Sandro Fioretti, Laura Burattini, Valentina Agostini, Marco Knaflitz, Francesco Di Nardo
The research purpose was to quantify the co-contraction patterns of quadriceps femoris (QF) vs. hamstring muscles during free walking, in terms of onset-offset muscular activation, excitation intensity, and occurrence frequency. Statistical gait analysis was performed on surface-EMG signals from vastus lateralis (VL), rectus femoris (RF), and medial hamstrings (MH), in 16315 strides walked by 30 healthy young adults. Results showed full superimpositions of MH with both VL and RF activity from terminal swing, 80 to 100% of gait cycle (GC), to the successive loading response (≈0-15% of GC), in around 90% of the considered strides...
January 2017: Gait & Posture
https://www.readbyqxmd.com/read/27811292/an-exploratory-clustering-approach-for-extracting-stride-parameters-from-tracking-collars-on-free-ranging-wild-animals
#17
Oliver P Dewhirst, Kyle Roskilly, Tatjana Y Hubel, Neil R Jordan, Krystyna A Golabek, J Weldon McNutt, Alan M Wilson
Changes in stride frequency and length with speed are key parameters in animal locomotion research. They are commonly measured in a laboratory on a treadmill or by filming trained captive animals. Here we show that a clustering approach can be used to extract these variables from data collected by a tracking collar containing a GPS module and tri-axis accelerometers and gyroscopes. The method enables stride parameters to be measured during free ranging locomotion in natural habitats. As it does not require labelled data it is particularly suitable for use with difficult to observe animals...
November 3, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27802151/the-private-life-of-echidnas-using-accelerometry-and-gps-to-examine-field-biomechanics-and-assess-the-ecological-impact-of-a-widespread-semi-fossorial-monotreme
#18
Christofer J Clemente, Christine E Cooper, Philip C Withers, Craig Freakley, Surya Singh, Philip Terrill
The short-beaked echidna (Tachyglossus aculeatus) is a monotreme and therefore provides a unique combination of phylogenetic history, morphological differentiation and ecological specialisation for a mammal. The echidna has a unique appendicular skeleton, a highly specialised myrmecophagous lifestyle and a mode of locomotion that is neither typically mammalian nor reptilian, but has aspects of both lineages. We therefore were interested in the interactions of locomotor biomechanics, ecology and movements for wild, free-living short-beaked echidnas...
October 15, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27779121/the-effect-of-particle-density-on-ultrasound-mediated-transport-of-nanoparticles
#19
Harriet Lea-Banks, Boon Teo, Eleanor Stride, Constantin C Coussios
A significant barrier to successful drug delivery is the limited penetration of nanoscale therapeutics beyond the vasculature. Building on recent in vivo findings in the context of cancer drug delivery, the current study investigates whether modification of nanoparticle drug-carriers to increase their density can be used to enhance their penetration into viscoelastic materials under ultrasound exposure. A computational model is first presented to predict the transport of identically sized nanoparticles of different densities in an ultrasonic field in the presence of an oscillating microbubble, by a combination of primary and secondary acoustic radiation forces, acoustic streaming and microstreaming...
November 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27712662/effect-of-stride-frequency-on-thermoregulatory-responses-during-endurance-running-in-distance-runners
#20
Tatsuro Amano, Masaki Ishitobi, Yukio Ogura, Yoshimitsu Inoue, Shunsaku Koga, Takeshi Nishiyasu, Narihiko Kondo
Changing stride frequency may influence oxygen uptake and heart rate during running as a function of running economy and central command. This study investigated the influence of stride frequency manipulation on thermoregulatory responses during endurance running. Seven healthy endurance runners ran on a treadmill at a velocity of 15km/h for 60min in a controlled environmental chamber (ambient temperature 27°C and relative humidity 50%), and stride frequency was manipulated. Stride frequency was intermittently manipulated by increasing and decreasing frequency by 10% from the pre-determined preferred frequency...
October 2016: Journal of Thermal Biology
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