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https://www.readbyqxmd.com/read/28317756/blue-light-dosage-affects-carotenoids-and-tocopherols-in-microgreens
#1
Giedrė Samuolienė, Akvilė Viršilė, Aušra Brazaitytė, Julė Jankauskienė, Sandra Sakalauskienė, Viktorija Vaštakaitė, Algirdas Novičkovas, Alina Viškelienė, Audrius Sasnauskas, Pavelas Duchovskis
Mustard, beet and parsley were grown to harvest time under selected LEDs: 638+660+731+0% 445nm; 638+660+731+8% 445nm; 638+660+731+16% 445nm; 638+660+731+25% 445nm; 638+660+731+33% 445nm. From 1.2 to 4.3 times higher concentrations of chlorophylls a and b, carotenoids, α- and β-carotenes, lutein, violaxanthin and zeaxanthin was found under blue 33% treatment in comparison to lower blue light dosages. Meanwhile, the accumulation of metabolites, which were not directly connected with light reactions, such as tocopherols, was more influenced by lower (16%) blue light dosage, increasing about 1...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28304107/the-percutaneous-toxicokinetics-of-sulphur-mustard-in-a-damaged-skin-porcine-model-and-the-evaluation-of-woundstat%C3%A2-as-a-topical-decontaminant
#2
Charlotte A Hall, Helen L Lydon, Christopher H Dalton, J Kevin Chipman, John S Graham, Robert P Chilcott
This study used a damaged skin, porcine model to evaluate the in vivo efficacy of WoundStat™ for decontamination of superficial (non-haemorrhaging), sulphur mustard-contaminated wounds. The dorsal skin of 12 female pigs was subjected to controlled physical damage and exposed to 10 μL (14) C-radiolabelled sulphur mustard ((14) C-SM). Animals were randomly assigned to either a control or a treatment group. In the latter, WoundStat™ was applied 30 s post exposure and left in situ for 1 h. Skin lesion progression and decontaminant efficacy were quantified over 6 h using a range of biophysical measurements...
March 17, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28299009/clinical-practice-guidelines-for-prevention-diagnosis-and-management-of-early-and-delayed-onset-ocular-injuries-due-to-mustard-gas-exposure
#3
Zhale Rajavi, Sare Safi, Mohammad Ali Javadi, Mohammad Reza Jafarinasab, Sepehr Feizi, Mohammadreza Sedighi Moghadam, Khosrow Jadidi, Mahmoud Babaei, Armin Shirvani, Alireza Baradaran-Rafii, Hossein Mohammad-Rabei, Hossein Ziaei, Mohammad Ghassemi-Broumand, Siamak Delfaza Baher, Mostafa Naderi, Mahmoodreza Panahi-Bazaz, Siamak Zarei-Ghanavati, Shahriar Hanjani, Hassan Ghasemi, Ramin Salouti, Mojgan Pakbin, Bahareh Kheiri
PURPOSE: To develop clinical practice guidelines (CPGs) for prevention, diagnosis, treatment and follow-up of ocular injuries caused by exposure to mustard gas. METHODS: The clinical questions were designed by the guideline team. Websites and databases including National Guidelines Clearinghouse, National Institute for Clinical Excellence, Cochrane, and PubMed were searched to find related CPGs and explore possible answers to the clinical questions. Since there were no relevant CPGs in the literature, related articles in Persian and English languages were extracted...
January 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28298999/mustard-gas-induced-ocular-injuries
#4
EDITORIAL
Mohammad Ali Javadi
No abstract text is available yet for this article.
January 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28291541/evidence-for-a-novel-neurohumoral-antinociceptive-mechanism-mediated-by-peripheral-capsaicin-sensitive-nociceptors-in-conscious-rats
#5
Gábor Pethő, Kata Bölcskei, Réka Füredi, Bálint Botz, Teréz Bagoly, Erika Pintér, János Szolcsányi
Stimulation of capsaicin-sensitive peripheral sensory nerve terminals induces remote anti-inflammatory effects throughout the body of anesthetized rats and guinea-pigs mediated by somatostatin. As somatostatin has also antinociceptive effects, the study aimed at investigating whether similar remote antinociceptive effects can be demonstrated in awake animals. In conscious rats, nociceptive nerve endings of the right hind paw decentralized by cutting the sciatic and saphenous nerves 18h before were chemically stimulated, and drop of the noxious heat threshold (heat hyperalgesia) induced by prior (18h before) plantar incision was measured on the contralateral, left hind paw using an increasing-temperature water bath...
February 10, 2017: Neuropeptides
https://www.readbyqxmd.com/read/28288793/a-novel-zebrafish-based-model-of-nociception
#6
J Christopher Taylor, L Savannah Dewberry, Stacie K Totsch, Lindsey R Yessick, Jennifer J DeBerry, Stephen A Watts, Robert E Sorge
Chronic pain affects the lives of millions yearly, but few new treatments are available. Due to decreasing budgets and increasing costs of preclinical research, alternatives are sought with high translatability and low cost. Here we demonstrate the utility of a zebrafish-based model of nociception to serve as a novel screening tool for analgesic drugs. Zebrafish swimming behavior was measured following administration of various algogens including histamine, cinnamaldehyde, mustard oil, acetic acid and complete Freund's adjuvant...
March 10, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28286669/long-term-complications-of-sulfur-mustard-poisoning-retinal-electrophysiological-assessment-in-40-severely-intoxicated-iranian-veterans
#7
Nasser Shoeibi, Mir Naghi Mousavi, Mahdi Balali-Mood, Mohammad Moshiri, Emadodin Darchini-Maragheh, Seyed Reza Mousavi, Mojtaba Abrishami
BACKGROUND: The eye is one of the most sensitive organs to sulfur mustard (SM) [C4H8Cl2S], and preliminary symptoms of exposure usually become evident in the eyes. In this study we aim to evaluate the possible long-term retinal electrophysiologic complications of SM poisoning in Iranian veterans during Iran-Iraq war (1980-1988). METHODS: In a cross-sectional study forty Iranian veterans who were exposed to mustard gas during the Iran-Iraq war (1980-1988) were included...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/28285329/intravascular-ultrasound-to-assess-for-baffle-stenosis-after-mustard-procedure
#8
Lane B Benes, Jonathan R Rosenberg, Cevher Ozcan, Tharian S Cherian, Atman P Shah
No abstract text is available yet for this article.
March 11, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28285128/using-mustard-genomes-to-explore-the-genetic-basis-of-evolutionary-change
#9
REVIEW
Lachezar A Nikolov, Miltos Tsiantis
Recent advances in sequencing technologies and gene manipulation tools have driven mustard species into the spotlight of comparative research and have offered powerful insight how phenotypic space is explored during evolution. Evidence emerged for genome-wide signal of transcription factors and gene duplication contributing to trait divergence, e.g., PLETHORA5/7 in leaf complexity. Trait divergence is often manifested in differential expression due to cis-regulatory divergence, as in KNOX genes and REDUCED COMPLEXITY, and can be coupled with protein divergence...
March 8, 2017: Current Opinion in Plant Biology
https://www.readbyqxmd.com/read/28285101/comparative-toxicity-of-mono-and-bifunctional-alkylating-homologues-of-sulphur-mustard-in-human-skin-keratinocytes
#10
Thomas W Sawyer, Karin McNeely, Kristen Louis, Pierre Lecavalier, Yanfeng Song, Mercy Villanueva, Robin Clewley
Sulphur mustard (bis(2-chloroethyl) sulphide; agent H) is a vesicant chemical warfare (CW) agent whose mechanism of action is not known with any certainty and for which there are no effective antidotes. It has a pronounced latent period before signs and symptoms of poisoning appear which it shares with the nitrogen mustards, and that differentiates it from other classes of vesicant agents. Sulphur mustard, the sulphur mustard CW agents Q (1,2-bis(2-chloroethylthio) ethane) and T (1,1 bis(2-chloroethylthioethyl) ether), the H partial hydrolysis product hemi-sulphur mustard (2-chloroethyl 2-hydroxyethyl sulphide; HSM), and the commercially available 2-chloroethyl ethyl sulphide (CEES) were characterized with respect to their toxicity in first passage cultures of proliferating human skin keratinocytes, the target cell of H-induced skin vesication...
March 8, 2017: Toxicology
https://www.readbyqxmd.com/read/28284764/simultaneous-quantification-of-four-metabolites-of-sulfur-mustard-in-urine-samples-by-ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry-after-solid-phase-extraction
#11
Chang-Cai Liu, Shi-Lei Liu, Hai-Ling Xi, Hui-Lan Yu, Shi-Kun Zhou, Gui-Lan Huang, Long-Hui Liang, Jing-Quan Liu
Four HD urinary metabolites including hydrolysis metabolite thiodiglycol (TDG), glutathione-derived metabolite 1,1'-sulfonylbis[2-S-(N-acetylcysteinyl)ethane] (SBSNAE), as well as the β-lyase metabolites 1,1'-sulfonylbis[2-(methylsulfinyl)ethane] (SBMSE) and 1-methylsulfinyl-2-[2-(methylthio) ethylsulfonyl]ethane (MSMTESE) are considered as important biomarkers for short-term retrospective detection of HD exposure. In this study, a single method for simultaneous quantification of the four HD metabolites in urine samples was developed using ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)...
February 27, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28279874/high-throughput-quantitative-analysis-of-the-%C3%AE-lyase-sulfur-mustard-metabolite-1-1-sulfonylbis-2-methylsulfinyl-ethane-in-urine-via-high-performance-liquid-chromatography-tandem-mass-spectrometry
#12
Martin J Bevan, Matthew T Wogen, Mark D Lunda, Stefan A Saravia
Sulfur Mustard (HD) has a 100year history of use as a chemical warfare agent and recent events in the Middle East are causing it to once again be a potential concern. We report a new high-throughput method for the determination of HD exposure by the analysis of the β-lyase metabolite 1,1'-sulfonylbis[2-(methylsulfinyl)ethane] (SBMSE) in human urine. This method features a hydrogen peroxide (H2O2) oxidative conversion of the β-lyase metabolites to SBMSE, followed by sample extraction and concentration using solid phase extraction in 96-well plate format...
March 3, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28265215/nonfluoroscopic-imaging-as-guidance-for-radiofrequency-ablation-of-atrioventricular-nodal-reentrant-tachycardia-after-mustard-repair
#13
Jan Hluchy, Dinh Q Nguyen, Henrik Sobczak, Bodo Brandts
Most tachycardias in the pulmonary venous atrium are inaccessible by direct means and require either a retrograde approach or a transseptal approach for ablation. We present a case in which successful radiofrequency ablation of common atrioventricular nodal reentrant tachycardia was accomplished via a retrograde transaortic approach guided by nonfluoroscopic mapping with use of the NavX(™) mapping system. The patient was a 49-year-old woman who at the age of 4 years had undergone Mustard repair for complete dextrotransposition of the great arteries...
February 2017: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28265208/effectiveness-of-early-invasive-therapy-for-atrial-tachycardia-in-adult-atrial-baffle-survivors
#14
Elisa A Bradley, Ali N Zaidi, Justin Morrison, Curt J Daniels, Steven Kalbfleisch, Naomi J Kertesz
Adults who underwent complex atrial baffling as children via Mustard or Senning procedures are at heightened risk for atrial arrhythmias. Antiarrhythmic therapies are typically ineffective in this population. Accordingly, our team of pediatric and adult electrophysiologists investigated the effectiveness of early invasive transbaffle-access techniques to perform early radiofrequency ablation at the source of these clinically significant arrhythmias. For this retrospective study, we selected 11 adult survivors of atrial baffling (mean age, 34 ± 9 yr) who underwent clinically indicated electrophysiologic study after no more than one trial of antiarrhythmic therapy...
February 2017: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28249298/the-modern-japanese-color-lexicon
#15
Ichiro Kuriki, Ryan Lange, Yumiko Muto, Angela M Brown, Kazuho Fukuda, Rumi Tokunaga, Delwin T Lindsey, Keiji Uchikawa, Satoshi Shioiri
Despite numerous prior studies, important questions about the Japanese color lexicon persist, particularly about the number of Japanese basic color terms and their deployment across color space. Here, 57 native Japanese speakers provided monolexemic terms for 320 chromatic and 10 achromatic Munsell color samples. Through k-means cluster analysis we revealed 16 statistically distinct Japanese chromatic categories. These included eight chromatic basic color terms (aka/red, ki/yellow, midori/green, ao/blue, pink, orange, cha/brown, and murasaki/purple) plus eight additional terms: mizu ("water")/light blue, hada ("skin tone")/peach, kon ("indigo")/dark blue, matcha ("green tea")/yellow-green, enji/maroon, oudo ("sand or mud")/mustard, yamabuki ("globeflower")/gold, and cream...
March 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28246442/effects-of-different-vegetable-oils-on-rumen-fermentation-and-conjugated-linoleic-acid-concentration-in-vitro
#16
Amitava Roy, Guru Prasad Mandal, Amlan Kumar Patra
AIM: The objective of this study was to investigate the effect of different vegetable oils on rumen fermentation and concentrations of beneficial cis-9 trans-11 C18:2 conjugated linoleic acid (CLA) and trans-11 C18:1 fatty acid (FA) in the rumen fluid in an in vitro condition. MATERIALS AND METHODS: Six vegetable oils including sunflower, soybean, sesame, rice bran, groundnut, and mustard oils were used at three dose levels (0%, 3% and 4% of substrate dry matter [DM] basis) in three replicates for each treatment in a completely randomized design using 6 × 3 factorial arrangement...
January 2017: Veterinary World
https://www.readbyqxmd.com/read/28246228/war-what-is-it-good-for-mustard-gas-medicine
#17
Susan L Smith
No abstract text is available yet for this article.
February 27, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28244149/eukaryotic-translation-initiation-factor-2b-beta-eif2b%C3%AE-a-new-class-of-plant-virus-resistance-gene
#18
Shopan Jannat, Haipeng Mou, Lili Zhang, Changtong Zhang, Weiwei Ma, John A Walsh, Zhongyuan Hu, Jinghua Yang, Mingfang Zhang
Recessive resistances to plant viruses in the Potyvirus genus have been found to be based on mutations in the plant eukaryotic translation initiation factors, eIF4E and eIF4G or their isoforms. Here we report that natural, monogenic recessive resistance to the potyvirus Turnip mosaic virus (TuMV) has been found in a number of mustard (Brassica juncea) accessions. Bulked segregant analysis and sequencing of resistant and susceptible plant lines indicated the resistance is controlled by a single recessive gene, recessive TuMV resistance 03 (retr03), an allele of the eukaryotic translation initiation factor 2B-beta (eIF2Bβ)...
February 28, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28238109/erythrocyte-fatty-acid-composition-of-nepal-breast-fed-infants
#19
Sigrun Henjum, Øyvind Lie, Manjeswori Ulak, Andrew L Thorne-Lyman, Ram K Chandyo, Prakash S Shrestha, Wafaie W Fawzi, Tor A Strand, Marian Kjellevold
PURPOSE: Essential fatty acids play a critical role in the growth and development of infants, but little is known about the fatty acid status of populations in low-income countries. The objective was to describe the fatty acid composition of red blood cells (RBC) in breastfeed Nepali infants and a subsample of their mothers and to identify the main sources of fatty acids in the mother's diet, as well as the fatty acid composition of breast milk. METHODS: RBC fatty acid composition was analyzed in a random sample of 303 infants and 72 mother, along with 68 breastmilk samples...
February 25, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28236387/simultaneous-analysis-of-oil-soluble-basic-and-acidic-illegal-dyes-in-foods-using-liquid-chromatography-diode-array-detection
#20
Yoko Uematsu, Toshiko Mizumachi, Kimio Monma
A method for simutaneously detecting 8 oil-soluble and 10 water-soluble (3 basic and 7 acidic) illegal dyes in foods was developed. The sample was mixed with water, followed by methanol and tetrahydrofuran. Transesterification with sodium methoxide was applied to the mixture, which allowed the triglycerides in the sample to be converted to fatty acid methyl esters. This treatment resulted in a biphasic mixture. Oil-soluble dyes and fatty acid methyl esters were deposited in the upper organic phase, which was cleaned using a silica-gel solid-phase extraction (SPE) column to remove the fatty acid methyl esters from the solution...
February 25, 2017: Journal of AOAC International
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