keyword
MENU ▼
Read by QxMD icon Read
search

mustard

keyword
https://www.readbyqxmd.com/read/29149779/increased-genes-expression-levels-of-cytokines-related-to-th17-treg-cells-in-peripheral-blood-mononuclear-cell-correlate-with-clinical-severity-in-copd-and-mustard-gas-exposed-patients
#1
Parisa Farahani, Raheleh Halabian, Ensieh Vahedi, Jafar Salimian
The long lasting inflammation and immune dysregulation is one of the main mechanisms involved in lung complication of veterans exposed to sulfur mustard (SM) gas. Th17/Treg cells have an important role in immunopathogenesis of chronic obstructive pulmonary disease (COPD) and mustard lung disease. In this study, expression of cytokines genes levels related to Th17/Treg cells was determined in peripheral blood mononuclear (PBMC) of mustard lung patients and was compared with COPD patients and healthy controls (HC)...
October 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29146724/commentary-nocturnal-serum-melatonin-levels-in-sulfur-mustard-exposed-patients-with-sleep-disorders
#2
EDITORIAL
Surg Cdr S A Bland
No abstract text is available yet for this article.
November 16, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29146723/nocturnal-serum-melatonin-levels-in-sulfur-mustard-exposed-patients-with-sleep-disorders
#3
Seyyedeh Soghra Mousavi, E Vahedi, M Shohrati, Y Panahi, S Parvin
BACKGROUND: Sulfur mustard (SM) exposure causes respiratory disorders, progressive deterioration in lung function and mortality in injured victims and poor sleep quality is one of the most common problems among SM-exposed patients. Since melatonin has a critical role in regulation of sleep and awareness, this study aimed to evaluate the serum melatonin levels in SM-injured subjects. METHODS: A total of 30 SM-exposed male patients and 10 controls was evaluated. Sleep quality was evaluated by the Pittsburgh Sleep Quality Index (PSQI); daytime sleepiness was measured by the Epworth Sleepiness Scale (ESS), and the risk of obstructive sleep apnoea was determined by the STOP-Bang questionnaire...
November 16, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29141200/phosgene-oxime-injury-and-associated-mechanisms-compared-to-vesicating-agents-sulfur-mustard-and-lewisite
#4
Dinesh Giri Goswami, Rajesh Agarwal, Neera Tewari-Singh
Phosgene Oxime (CX, Cl2CNOH), a halogenated oxime, is a potent chemical weapon that causes immediate acute injury and systemic effects. CX, grouped together with vesicating agents, is an urticant or nettle agent with highly volatile, reactive, corrosive, and irritating vapor, and has considerably different chemical properties and toxicity compared to other vesicants. CX is absorbed quickly through clothing with faster cutaneous penetration compared to other vesicating agents causing instantaneous and severe damage...
November 12, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/29129815/biological-effects-of-adipocytes-in-sulfur-mustard-induced-toxicity
#5
Hua Xu, Zhongcai Gao, Peng Wang, Bin Xu, Yajiao Zhang, Long Long, Cheng Zong, Lei Guo, Weijian Jiang, Qinong Ye, Lili Wang, Jianwei Xie
Sulphur mustard (2,2'-dichloroethyl sulfide; SM) is a vesicant chemical warfare agent whose mechanism of acute or chronic action is not known with any certainty and to date there is no effective antidote. SM accumulation in adipose tissue (AT) has been originally verified in our previous study. To evaluate the biological effect caused by the presence of abundant SM in adipocyte and assess the biological role of AT in SM poisoning, in vitro and in vivo experiments were performed. High content analysis revealed multi-cytotoxicity in SM exposed cells in a time and dose dependent manner, and adipocytes showed a relative moderate damage compared with non-adipocytes...
November 9, 2017: Toxicology
https://www.readbyqxmd.com/read/29129753/nitrogen-mustard-induced-corneal-injury-involves-the-sphingomyelin-ceramide-pathway
#6
Georgia Charkoftaki, James Jester, David Thompson, Vasilis Vasiliou
PURPOSE: Nitrogen mustard (NM), which simulates the effects of sulfur mustard (SM), is a potent vesicant known to cause irreversible corneal damage. This study investigates the mechanisms by which NM induces corneal damage by examining the impact of NM exposure on the morphology and lipidome of the cornea. METHODS: Intact ex vivo rabbit eyes were placed in serum-free DMEM organ culture. NM (0, 1, 2.5, 5 or 10 mg/ml) was applied to the central cornea for 5, 10 or 15 min using a 5 mm filter disk and subsequently rinsed with DMEM...
November 9, 2017: Ocular Surface
https://www.readbyqxmd.com/read/29127031/sulfur-mustard-induced-mast-cell-degranulation-in-mouse-skin-is-inhibited-by-a-novel-anti-inflammatory-and-anticholinergic-bifunctional-prodrug
#7
Laurie B Joseph, Gabriella M Composto, Roberto M Perez, Hong-Duck Kim, Robert P Casillas, Ned D Heindel, Sherri C Young, Carl J Lacey, Jaya Saxena, Christophe D Guillon, Claire R Croutch, Jeffrey D Laskin, Diane E Heck
Sulfur mustard (SM, bis(2-chloroethyl sulfide) is a potent vesicating agent known to cause skin inflammation, necrosis and blistering. Evidence suggests that inflammatory cells and mediators that they generate are important in the pathogenic responses to SM. In the present studies we investigated the role of mast cells in SM-induced skin injury using a murine vapor cup exposure model. Mast cells, identified by toluidine blue staining, were localized in the dermis, adjacent to dermal appendages and at the dermal/epidermal junction...
November 7, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/29121206/effects-of-temperatures-on-immature-development-and-survival-of-the-invasive-stink-bug-hemiptera-pentatomidae
#8
Darcy A Reed, Fatemeh Ganjisaffar, John C Palumbo, Thomas M Perring
Bagrada hilaris (Burmeister) (Hemiptera: Pentatomidae) is a non-native stink bug that feeds primarily on cole crops and wild mustards. Its invasion into desert agriculture in California and Arizona presents a conundrum between rapid pest development at warm temperatures and severe damage to cool season crops. In this study, the development and survival of B. hilaris were determined at nine constant temperatures (ranging from 20-42°C) when reared on organically grown broccoli florets. Egg hatching was greatly delayed at 20°C, and first instar nymphs did not survive at this temperature...
November 7, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29120456/indicators-of-skin-barrier-integrity-among-newborns-massaged-with-mustard-oil-in-rural-nepal
#9
A Summers, M O Visscher, S K Khatry, J B Sherchand, S C LeClerq, J Katz, J M Tielsch, L C Mullany
OBJECTIVE: The objective of this study was to determine the skin barrier changes during postnatal month 1 among infants receiving routine mustard oil massage in the humid conditions of rural Nepal. STUDY DESIGN: This was an observational study among 500 live-born neonates receiving mustard oil massage. Skin integrity such as erythema, rash, dryness, skin pH, stratum corneum protein concentration and transepidermal water loss was measured on days 1, 3, 7, 14 and 28...
November 9, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29120115/quantitative-determination-of-acidic-hydrolysis-products-of-chemical-weapons-convention-related-chemicals-from-aqueous-and-soil-samples-using-ion-pair-solid-phase-extraction-and-in-situ-butylation
#10
Suresh Pal Anagoni, Asma Kauser, Gopal Maity, Vijayasarathi V R Upadhyayula
Chemical warfare agents such as organophospshorus nerve agents, mustard agents, and psychotomimetic agent like 3-quinuclidinylbenzilate degrade in the environment and form acidic degradation products the analysis of which is difficult under normal analytical conditions. In the present work a simultaneous extraction and derivatization method in which the analytes are butylated followed by gas chromatography and mass spectrometric identification of the analytes from aqueous and soil samples was carried out. The extraction was carried out using ion-pair solid-phase extraction with tetrabutylammonium hydroxide followed by gas chromatography with mass spectrometry in the electron ionization mode...
November 9, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/29111232/antagonism-in-effectiveness-of-evofosfamide-and-doxorubicin-through-intermolecular-electron-transfer
#11
Robert F Anderson, Dan Li, Francis W Hunter
Hypoxic cells pose a problem in anticancer chemotherapy, in which often drugs require oxygen as an electron acceptor to bring about the death of actively cycling cells. Bioreductive anticancer drugs, which are selectively activated in the hypoxic regions of tumours through enzymatic one-electron reduction, are being developed for combination with chemotherapy-, radiotherapy- and immunotherapy-containing regimens to kill treatment-resistant hypoxic cells. The most clinically-advanced bioreductive drug, evofosfamide (TH-302), which acts by releasing a DNA-crosslinking mustard, failed to extend overall survival in combination with doxorubicin, a topoisomerase II inhibitor, for advanced soft tissue sarcoma in a pivotal clinical trial...
October 28, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29107252/trp574-substitution-in-the-acetolactate-synthase-of-sinapis-arvensis-confers-cross-resistance-to-tribenuron-and-imazamox
#12
S Ntoanidou, P Madesis, G Diamantidis, I Eleftherohorinos
Rate-response experiments with nine putative resistant wild mustard (Sinapis arvensis) populations from Greece showed cross-resistance to tribenuron and imazamox. The calculated GR50 values [herbicide rate (gaiha(-1)) required for 50% reduction of fresh weight] of the nine resistant (R) populations ranged from 51.8 to 555.6gaitribenuronha(-1) and from 66.3 to 900.4gaiimazamoxha(-1). Regarding the susceptible population, GR50 value was not estimated for tribenuron as its lower treatment reduced fresh weight by >95%, whereas the respective value for imazamox was 0...
October 2017: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/29096309/evaluation-of-acute-and-chronic-ecotoxicity-of-cyclophosphamide-ifosfamide-their-metabolites-transformation-products-and-uv-treated-samples
#13
Chiara Russo, Margherita Lavorgna, Marjeta Česen, Tina Kosjek, Ester Heath, Marina Isidori
Cyclophosphamide (CP) and Ifosfamide (IF) are two nitrogen mustard drugs widely prescribed in cancer therapy. They are continuously released via excreta into hospital and urban wastewaters reaching wastewater treatment plants. Although CP and IF, their metabolites and transformation products (TPs) residues have been found in the aquatic environment from few ng L(-1) to tens of μg L(-1), their environmental toxic effects are still not well known. The present study aimed to investigate the acute and chronic ecotoxicity of CP and IF and their commercially available human metabolites/TPs, i...
October 27, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29078194/desorption-of-sulphur-mustard-simulants-methyl-salicylate-and-2-chloroethyl-ethyl-sulphide-from-contaminated-scalp-hair-after-vapour-exposure
#14
Marie Spiandore, Mélanie Souilah-Edib, Anne Piram, Alexandre Lacoste, Denis Josse, Pierre Doumenq
Chemical warfare agents have been used to incapacitate, injure or kill people, in a context of war or terrorist attack. It has previously been shown that hair could trap the sulphur mustard simulants methyl salicylate and 2-chloroethyl ethyl sulphide. In order to investigate simulants persistency in hair after intense vapour exposure, their desorption kinetics were studied by using two complementary methods: hair residual content measurement and desorbed vapour monitoring. Results showed that both simulants were detected in air and could be recovered from hair 2 h after the end of exposure...
September 26, 2017: Chemosphere
https://www.readbyqxmd.com/read/29076159/lichen-planus-pigmentosus-and-its-variants-review-and-update
#15
REVIEW
Juan Carlos Robles-Méndez, Paulina Rizo-Frías, Maira Elizabeth Herz-Ruelas, Amit G Pandya, Jorge Ocampo Candiani
Lichen planus pigmentosus (LPP) is considered a rare variant of lichen planus (LP). It is characterized by acquired dark brown to gray macular pigmentation located on sun-exposed areas of the face, neck, and flexures, commonly found in dark-skinned patients. In patients with LPP, an inflammatory lichenoid response results in marked pigmentary incontinence. It has been associated with hepatitis C virus, sun exposure, and contactants such as mustard oil and nickel. LPP-inversus affects fair and dark skin, predominantly involving flexural and intertriginous areas, while sun-exposed areas are spared; friction is an associated trigger...
October 26, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/29075270/differential-phytotoxic-impact-of-plant-mediated-silver-nanoparticles-agnps-and-silver-nitrate-agno3-on-brassica-sp
#16
Kanchan Vishwakarma, Shweta, Neha Upadhyay, Jaspreet Singh, Shiliang Liu, Vijay P Singh, Sheo M Prasad, Devendra K Chauhan, Durgesh K Tripathi, Shivesh Sharma
Continuous formation and utilization of nanoparticles (NPs) have resulted into significant discharge of nanosized particles into the environment. NPs find applications in numerous products and agriculture sector, and gaining importance in recent years. In the present study, silver nanoparticles (AgNPs) were biosynthesized from silver nitrate (AgNO3) by green synthesis approach using Aloe vera extract. Mustard (Brassica sp.) seedlings were grown hydroponically and toxicity of both AgNP and AgNO3 (as ionic Ag(+)) was assessed at various concentrations (1 and 3 mM) by analyzing shoot and root length, fresh mass, protein content, photosynthetic pigments and performance, cell viability, oxidative damage, DNA degradation and enzyme activities...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29071965/-inhibitory-effect-of-acupoint-application-on-airway-remodeling-and-expression-of-tgf-%C3%AE-1-smad-3-in-the-lung-tissue-of-chronic-asthma-mice
#17
Cheng-Yong Liu, Shan Qin, Lan-Ying Liu, Ya-Min He, He-Sheng Wang, Wen-Zhong Wu, Dong Chen, Cong Zhang
OBJECTIVE: To observe the effect of acupoint application on transforming growth factor (TGF)-β 1/Smad 3 signaling pathway, so as to reveal its mechanism underlying improvement of airway remodeling in chronic asthma mice. METHODS: BALB/c mice were randomly divided into normal group,model group,sham acupoint application group (sham group),acupoint application group, and dexamethasone group (n=8 in each group). The chronic asthma model was established by intraperitoneal injection of ovalbumin sensitization...
April 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29070564/no-metabolic-effects-of-mustard-allyl-isothiocyanate-compared-with-placebo-in-men
#18
Mirjam Langeveld, Chong Yew Tan, Maarten R Soeters, Samuel Virtue, Laura Pe Watson, Peter R Murgatroyd, Graeme K Ambler, Santiago Vidal-Puig, Krishna V Chatterjee, Antonio Vidal-Puig
Background: Induction of nonshivering thermogenesis can be used to influence energy balance to prevent or even treat obesity. The pungent component of mustard, allyl-isothiocyanate (AITC), activates the extreme cold receptor transient receptor potential channel, subfamily A, member 1 and may thus induce energy expenditure and metabolic changes.Objective: The objective of our study was to evaluate the potential of mustard AITC to induce thermogenesis (primary outcome) and alter body temperature, cold and hunger sensations, plasma metabolic parameters, and energy intake (secondary outcomes)...
November 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29069930/long-term-health-effects-of-chemical-warfare-agents-on-children-following-a-single-heavy-exposure
#19
J M Talabani, A I Ali, A M Kadir, R Rashid, F Samin, D Greenwood, Awm Hay
In the 1980s, villages in the Kurdistan region of Iraq were exposed to chemical weapons (CWs), which killed and injured thousands of civilians. There has been no clinical assessment of the long-term effects of CWs exposure on those injured. We report the first such evaluation of CW effects on long-term health of children. Patients from the CW-exposed areas were interviewed to assess previous and current clinical history and underwent clinical examination. The status of organs known to be targets of CWs, including skin, eyes, respiratory and neuromuscular systems, was assessed...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/29068444/structural-convergence-properties-of-amorphous-ingazno4-from-simulated-liquid-quench-methods
#20
Jacob C Buchanan, Dylan B Fast, Benjamin E Hanken, Thomas J L Mustard, Geneva Laurita, Tsung-Han Chiang, Douglas A Keszler, Mas A Subramanian, John F Wager, Michelle R Dolgos, James R Rustad, Paul Ha-Yeon Cheong
The study of structural properties of amorphous structures is complicated by the lack of long-range order and necessitates the use of both cutting-edge computer modeling and experimental techniques. With regards to the computer modeling, many questions on convergence arise when trying to assess the accuracy of a simulated system. What cell size maximizes the accuracy while remaining computationally efficient? More importantly, does averaging multiple smaller cells adequately describe features found in bulk amorphous materials? How small is too small? The aims of this work are: (1) to report a newly developed set of pair potentials for InGaZnO4 and (2) to explore the effects of structural parameters such as simulation cell size and numbers on the structural convergence of amorphous InGaZnO4...
November 14, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
keyword
keyword
983
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"