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Injury assesment

Amrish Saxena, Shrikant V Meshram
Background: Acute kidney injury (AKI) is a challenging problem faced by intensive care clinicians worldwide, and it is associated with high morbidity and mortality, especially in critically ill patients. Materials and Methods: A hospital-based prospective, observational study was conducted in patients of AKI admitted to the Intensive Care Unit (ICU) of the Department of Medicine in a rural tertiary care hospital located in central India. Data of all consecutive AKI inpatients related to demographic variables, clinical profile, and laboratory investigations were collected from patient's medical records...
April 2018: Indian Journal of Critical Care Medicine
Syahirah Ahmad Sayuti Nurul, Hamzah Hazilawati, Rosly Shaari Mohd, Farhan Hanif Reduan Mohd, Mohamed Mustapha Noordin, Md Esa Norhaizan
The term Butterfly tea refers to decoction of Mariposa christia vespertilionis leaves which is widely consumed by cancer patients throughout Malaysia and has gained a huge popularity among Malaysians, not only cancer patients but also researchers to discover the real potential of this plant. Herein, the study is aimed at evaluating the possible toxicity in 28-day subacute oral toxicity of ethanolic extract M. christia vespertilionis in male Sprague Dawley rats. The 28-day subacute toxicity study was conducted to detect the no-observed adverse effect level (NOAEL)...
April 2018: Toxicological Research
Hanan Hosni Ahmed, Laila Ahmed Rashed, Sohair Mahfouz, Rania Elsayed Hussein, Marwa Alkaffas, Shaimaa Mostafa, Azza Abusree
Our aim was to study the effect of platelet-rich plasma (PRP) on the proliferation of bone-marrow-derived mesenchymal stem cells (BM-MSCs) and to investigate their roles in the healing of experimental burn injury and the possible mechanism of action. Our work was divided into in-vitro and in-vivo studies. The in-vitro study included untreated MSCs and MSCs treated with PRP. Levels of TGF-β and cell proliferation were assessed. In the in-vivo study, 72 rats were distributed equally among 6 groups: control, burn, burn with MSCs, burn with PRP, burn with both MSCs and PRP, and burn with MSCs pretreated with PRP...
October 2017: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
Jason Heath Vela, Christopher Ira Wertz, Kimberly L Onstott, Joss R Wertz
PURPOSE: To inform radiologic technologists about which imaging modalities and examinations are best suited for evaluating specific anatomical structures in patients who have sustained a traumatic injury. METHODS: Two scholarly research databases were searched to identify articles focused on trauma imaging of the head, cervical spine, thorax, abdomen, and pelvis. Articles focused on trauma diagnosis were excluded. Thirty-two articles were selected for analysis. DISCUSSION: Physical examination and plain-film radiographs typically are used to assess nasal bone fracures...
January 2017: Radiologic Technology
Ni Made Dwi Sandhiutami, Moordiani Moordiani, Dian Ratih Laksmitawati, Nurul Fauziah, Maesaroh Maesaroh, Wahyu Widowati
OBJECTIVES: Inflammation is an immune response toward injuries. Although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, Alzheimer's and various cancer. Indonesian cassia (Cinnamomum burmannil C. Nees & T. Ness) known to contain coumarin, is widely used for alternative medicine especially as an anti-inflammatory. This study was conducted to determine the anti-inflammatory properties of coumarin and Indonesian cassia extract (ICE) in LPS-induced RAW264...
January 2017: Iranian Journal of Basic Medical Sciences
Gul Deniz Yilmaz Yelvar, Yasemin Çirak, Murat Dalkilinç, Yasemin Parlak Demir, Gul Baltaci, Mahmut Kömürcü, Gul Deniz Yilmaz Yelvar
BACKGROUND: Postural control allows performance of daily and sports activities. The previous studies show that postural sway inceases in orthopaedic injuries such as osteoarthritis and total knee arthroplasty. OBJECTIVE: To compare postural sway, risk of falling and function between individuals with and without patellofemoral pain syndrome (PFS). METHODS: This study included 22 subjects with patellofemoral pain syndrome, age-matched pain-free 22 females serving as a control group...
June 30, 2016: Journal of Back and Musculoskeletal Rehabilitation
Emily P Sieg, Russell A Payne, Sprague Hazard, Elias Rizk
INTRODUCTION: Case reports, case series and case control studies have looked at the use of phrenic nerve stimulators in the setting of high spinal cord injuries and central hypoventilation syndromes dating back to the 1980s. We evaluated the evidence related to this topic by performing a systematic review of the published literature. METHODS: Search terms "phrenic nerve stimulation," "phrenic nerve and spinal cord injury," and "phrenic nerve and central hypoventilation" were entered into standard search engines in a systematic fashion...
June 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Silvia Mandello Carvalhaes, Andy Petroianu, Mauro Augusto Tostes Ferreira, Virgínea Magalhães de Barros, Raquel Virgínea Lopes
OBJECTIVE: To evaluate the combined treatment of ear lobe keloids. METHODS: We studied 46 consecutive patients with 81 ear lobe keloids. Patients underwent local infiltration of triamcinolone acetonide (TCN) at concentrations of 40 mg/ml (Group 1), 20 mg/ml (Group 2) and 10mg/ml (Group 3). The volume of TCN infiltrate varied according to the size of the lesion. Treatment consisted of three monthly injections before surgery, excision of keloid in the fourth month and perioperative infiltration, followed by two more leaks TCN within two months...
January 2015: Revista do Colégio Brasileiro de Cirurgiões
Qiulin Xu, Jingxian Liu, Xiaohua Guo, Youqing Tang, Gengbiao Zhou, Yanan Liu, Qiaobing Huang, Yan Geng, Zhifeng Liu, Lei Su
BACKGROUND: The pathogenesis of heatstroke is a multi-factorial process involved with an interplay among subsequent inflammation, endothelial injury and coagulation disturbances, which makes pharmacological therapy of heatstroke a challenging problem. Xuebijing injection (XBJ), a traditional Chinese medicine used to sepsis, has been reported to suppress inflammatory responses and restore coagulation disturbances. However, little is known about the role of XBJ in heatstroke. METHODS: Mice were treated with indicated dose of XBJ before and/or after the induction of heatstroke...
2015: BMC Complementary and Alternative Medicine
Alper Biler, Sait Yucebilgin, Fatih Sendag, Levent Akman, Ali Akdemir, Utku Ates, Yigit Uyanikgil, Ozlem Yilmaz-Dilsiz, Ebru Sezer
BACKGROUND: To determine the effects of different intraabdominal pressure (IAP) on the ovaries in a laparoscopic rat model. OBJECTIVES: The aim of the study was to determine the effects on the ovaries of different intraabdominal pressures (IAP) in laparoscopic surgery in a rat model. MATERIAL AND METHODS: Thirty-two post-pubertal nonpregnant Sprague-Dawley rats were divided randomly into four groups. In the control group, no intraabdominal pressure (IAP) was applied...
November 2014: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
(no author information available yet)
Experimental and clinical data have shown that there is an increase in the necessity of pyrimidine nucleotides after peripheral nerve injury. The aim of the study was to estimate the neuroprotective efficacy of the Nucleo CMP preparation (Nucleo CMP. Ferrer Internacional) containing cytidine monophosphate and uridine triphosphate nucleotides after unilateral compression of the sciatic nerve of rats. We recorded extracellular spike activity of single motoneurons of the spinal cord on the ipsilateral side towards injury during high frequency stimulation of distal collaterals (nervus tibialis and nervus peroneus communis) of the injured sciatic nerve...
February 2014: Rossiĭskii Fiziologicheskiĭ Zhurnal Imeni I.M. Sechenova
V A Chavushian, L R Gevorkian, K V Simonian
Experimental and clinical data have shown that there is an increase in the necessity of pyrimidine nucleotides after peripheral nerve injury. The aim of the study was to estimate the neuroprotective efficacy of the Nucleo CMP preparation (Nucleo CMP. Ferrer Internacional) containing cytidine monophosphate and uridine triphosphate nucleotides after unilateral compression of the sciatic nerve of rats. We recorded extracellular spike activity of single motoneurons of the spinal cord on the ipsilateral side towards injury during high frequency stimulation of distal collaterals (nervus tibialis and nervus peroneus communis) of the injured sciatic nerve...
February 2014: Rossiĭskii Fiziologicheskiĭ Zhurnal Imeni I.M. Sechenova
Jian-Hui Li, Long Guo, Wei-Jie Yao, Zhi-Yong Zhang, Shan-Pei Wang, Shi-Qi Liu, Zhi-Min Geng, Xiao-Ping Song, Yi Lv
OBJECTIVE: To assese the healing of stoma after magnetic anastomosis for the reconstruction of biliary-enteric continuity under severe inflammation. METHODS: Acute bile duct injury was constructed as a bile peritonitis model in mongrel dogs (n=32). Magnetic anastomosis (group A, n=16) and traditional suture anastomosis (group B, n=16) were performed to reconstruct the biliary-enteric continuity in one stage. Half of the dogs in each group were euthanized on the 30th postoperative day, and the other half on the 90th postoperative day to harvest the stoma region...
June 2014: Chinese Medical Sciences Journal, Chung-kuo i Hsüeh K'o Hsüeh Tsa Chih
Sara Tremblay, Vincent Beaulé, Sébastien Proulx, Sébastien Tremblay, Małgorzata Marjańska, Julien Doyon, Maryse Lassonde, Hugo Théoret
OBJECTIVE: Recent studies have shown, in asymptomatic concussed athletes, metabolic disruption in the primary motor cortex (M1) and abnormal intracortical inhibition lasting for more than six months. The present study aims to assess if these neurochemical and neurophysiological alterations are persistent and linked to M1 cortical thickness. METHODS: Sixteen active football players who sustained their last concussion, on average, three years prior to testing and 14 active football players who never sustained a concussion were recruited for a single session of proton magnetic resonance spectroscopy ((1)H-MRS) and transcranial magnetic stimulation (TMS)...
July 2014: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Nermina N Vagaja, Nicolette Binz, Samuel McLenachan, Elizabeth P Rakoczy, Paul G McMenamin
AIMS: To evaluate the impact of systemic exposure to bacterial lipopolysaccharide (LPS) on a rodent model of background diabetic retinopathy. METHODS: Toll-like receptor 4 (TLR4)-mediated systemic inflammation was induced in Ins2(Akita) heterozygotes and age-matched C57BL6/J-Ins2(+) littermates by single or repeated intraperitoneal injections of the TLR4 ligand LPS (9 µg/g body weight). 24 hours after a single injection in 7-week-old mice retinal Il1b, Tnfa and Vegf transcripts were measured with real-time PCR...
October 2013: British Journal of Ophthalmology
Claudia Espinosa-García, Rosa María Vigueras-Villaseñor, Julio César Rojas-Castañeda, Alejandra Aguilar-Hernández, Tomas Monfil, Miguel Cervantes, Gabriela Moralí
Delayed death of hippocampal CA1 pyramidal neurons following global cerebral ischemia/reperfusion may be mediated, in part, by caspase-3 activation resulting in DNA fragmentation. Progesterone (P4) is known to exert neuroprotective effects in several models of brain injury. This study was designed to assess the effect of P4 on caspase-3 levels and activation, and DNA fragmentation in the hippocampus following global cerebral ischemia/reperfusion. Adult male Sprague-Dawley rats were subjected to global ischemia by the four-vessel occlusion model...
August 29, 2013: Neuroscience Letters
Rebeca García-Nieto, Hilario Blasco-Fontecilla, Manuel Paz Yepes, Enrique Baca-García
INTRODUCTION: Most of the assesment tools used in our country examine a limited range of suicidal behaviours. In contrast, the Self-Injurious Thoughts and Behaviors Interview (SITBI), developed in the US, assesses a wider range of these behaviours: suicidal ideation, suicide attempt, suicidal gestures, and self-harming behaviours. Given this lack, we think it is necessary to validate the Escala de Pensamientos y Conductas Autolesivas (EPCA), Spanish translation of the SITBI, in the Spanish population...
July 2013: Revista de Psiquiatrí́a y Salud Mental
M Kenan Kinaci, Nilufer Erkasap, Aysegul Kucuk, Tulay Koken, Murat Tosun
The aim of this study was to investigate the effects of quercetin on nitric oxide synthase (NOS), nuclear factor-κB (NF-κB) and apoptosis in renal ischemia/reperfusion (I/R) injury in rats. A total of 42 Sprague-Dawley rats were divided into three groups. The control, I/R and I/R+quercetin (I/R+Q) groups were treated with quercetin (50 mg/kg intraperitoneal) 1 h prior to the induction of ischemia. Tissue malondialdehyde (MDA) and glutathione (GSH) levels were determined by high-performance liquid chromatography (HPLC)...
February 2012: Experimental and Therapeutic Medicine
Michał Poniński, Maciej Tokarski, Tomasz Andrzejewski, Piotr Czarnecki, Robert Spławski
Injuries of flexor tendons are one of the most common injuries that need surgical treatment at emergency room. Technique and quality of the surgery was performed are two factors of the utmost importance. The aim of the study was to determine influence of basic surgical training on the quality of suture. Research was divided into four surgical sessions which were held each once a week. Sutures were put by three medical students. Material that was used were deep flexor tendons dissected from fresh pig's legs...
September 2010: Chirurgia Narzadów Ruchu i Ortopedia Polska
Ksenija Miladinović
UNLABELLED: Prevalence of chronic pain which develops after spinal cord injury (SCI) varies, but in average is 65%. There are many questionnaires and scales for characterisation and classification of chronic SCI pain. One of them is LANSS (Leeds Assesment of Neuropathic Symptoms and Signs) scale for differentiation of neuropathic pain. Aims of this study were: (1) To assess prevalence of chronic pain in the sample of patients with SCl; (2) To classify the pain; (3) To analyse its correlations with demographic and neurological features as well as with activities of daily life (ADL); (4) To evaluate pain treatment...
2009: Medicinski Arhiv
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