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https://www.readbyqxmd.com/read/28731325/bioinspired-and-biomimetic-agnps-gentamicin-embedded-silk-fibroin-coatings-for-robust-antibacterial-and-osteogenetic-applications
#1
Wenhao Zhou, Zhaojun Jia, Pan Xiong, Jianglong Yan, Yangyang Li, Ming Li, Yan Cheng, Yufeng Zheng
With the progressively increasing demand for orthopedic Ti implants, the balance realization between two primary complications restricting implants applications is imperative needed to be solved that the lack of bone tissue integration and biomedical device-associated infections (BAI), where emergence of multi-resistance bacteria make it worse. Notably, a combination of silver nanoparticles (AgNPs) and a kind of antibiotic can synergistically inhibit bacterial growth, where low concentration of AgNPs has been confirmed to promote the proliferation and osteogenesis of osteoblasts...
July 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28730623/effects-of-fluoride-modified-titanium-surfaces-with-the-similar-roughness-on-runx2-gene-expression-of-osteoblast-like-mg63-cells
#2
Ji-Hyoun Lee, Jai-Young Koak, Young-Jun Lim, Ho-Beom Kwon, Hyunjoon Kong, Myung-Joo Kim
Chemical modification of titanium surfaces by hydrofluoric acid (HF) is an effective method to improve bone responses on titanium implant surfaces. In the present study, titanium disks were sandblasted with titanium oxide grits and modified with 0.2% and 0.4% of diluted HF under different exposure times of 40 and 60 s. Surface characteristics, such as surface chemical composition, surface topography, and surface wettability, were investigated. To examine MG63 osteoblast-like cell responses to fluoride-modified titanium surfaces with roughness similar to that of nonmodified surfaces, a cell proliferation assay was performed and gene expression levels of Runx2 were evaluated using real-time PCR...
July 21, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28730456/photofunctionalization-and-non-thermal-plasma-activation-of-titanium-surfaces
#3
Anders Henningsen, Ralf Smeets, Philip Hartjen, Oliver Heinrich, Roman Heuberger, Max Heiland, Clarissa Precht, Claudio Cacaci
OBJECTIVE: The aim of this study was to compare UV light and non-thermal plasma (NTP) treatment regarding the improvement of physical material characteristics and cell reaction on titanium surfaces in vitro after short-term functionalization. MATERIALS AND METHODS: Moderately rough (Ra 1.8-2.0 μm) sandblasted and acid-etched titanium disks were treated by UV light (0.05 mW/cm(2) at λ = 360 nm and 2 mW/cm(2) at λ = 250 nm) or by NTP (24 W, -0.5 mbar) of argon or oxygen for 12 min each...
July 20, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28728969/a-nanoporous-titanium-surface-promotes-the-maturation-of-focal-adhesions-and-the-formation-of-filopodia-with-distinctive-nanoscale-protrusions-by-osteogenic-cells
#4
Dainelys Guadarrama Bello, Aurélien Fouillen, Antonella Badia, Antonio Nanci
While topography is a key determinant of the cellular response to biomaterials the mechanisms implicated in the cell-surface interactions are complex and still not fully elucidated. In this context, we have examined the effect of nanoscale topography on the formation of filopodia, focal adhesions, and on gene expression of proteins associated with cell adhesion and sensing. Commercially pure titanium discs were treated for oxidative nanopatterning with a solution of H2SO4/H2O2 50:50 (v/v). Scanning electron microscopy and atomic force microscopy characterizations showed that this facile chemical treatment efficiently creates a unique nanoporous surface with a root-mean-square roughness of 11...
July 17, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28726761/a-cell-adhesive-plasma-polymerized-allylamine-coating-reduces-the-in-vivo-inflammatory-response-induced-by-ti6al4v-modified-with-plasma-immersion-ion-implantation-of-copper
#5
Uwe Walschus, Andreas Hoene, Maciej Patrzyk, Silke Lucke, Birgit Finke, Martin Polak, Gerold Lukowski, Rainer Bader, Carmen Zietz, Andreas Podbielski, J Barbara Nebe, Michael Schlosser
Copper (Cu) could be suitable to create anti-infective implants based on Titanium (Ti), for example by incorporating Cu into the implant surface using plasma immersion ion implantation (Cu-PIII). The cytotoxicity of Cu might be circumvented by an additional cell-adhesive plasma polymerized allylamine film (PPAAm). Thus, this study aimed to examine in vivo local inflammatory reactions for Ti6Al4V implants treated with Cu-PIII (Ti-Cu), alone or with an additional PPAAm film (Ti-Cu-PPAAm), compared to untreated implants (Ti)...
July 20, 2017: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/28721995/comparative-evaluation-of-laser-microtextured-implant-versus-machined-collar-implant-for-soft-and-hard-tissue-attachment-a-clinical-and-radiological-study
#6
Saroj Kumar Rath, Manab Kosala, Ankit Gupta
BACKGROUND: Various mechanical modifications in the collar region of endosseous implants is a challenge for better performance and osseointegration. Here is a comparative evaluation being carried out to find out the effect of the machined collar (MC) and Laser-Lok (LL)-modified titanium implants on the success of implants being commonly advocated in partially edentulous among serving personnel and their families. MATERIALS AND METHODS: Twenty-four patients with appropriate inclusion and exclusion criteria were selected for placement of Biohorizons MC and LL implants in 12 cases each...
May 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28721319/combined-sacroplasty-and-iliosacral-fixation-using-triangular-titanium-implants-for-the-treatment-of-sacral-insufficiency-fractures-with-concomitant-sacral-instability
#7
Ryan Johnson, Jason Seibly
Sacral insufficiency fractures (SIFs) are a common, under-recognized cause of debilitating low back pain, particularly in elderly patients with osteoporotic bone disease or risk factors for bone demineralization. Conservative therapy has been the mainstay of treatment for these types of fractures. This places patients at increased risk for the development of secondary illnesses associated with prolonged immobility, which might prevent a full return to the preinjury level of function. Surgical intervention for SIFs has increased over the past two decades in an attempt to overcome these complications and improve patient functionality...
June 14, 2017: Curēus
https://www.readbyqxmd.com/read/28721040/effect-of-ultraviolet-treatment-on-bacterial-attachment-and-osteogenic-activity-to-alkali-treated-titanium-with-nanonetwork-structures
#8
Honghao Zhang, Satoshi Komasa, Chiho Mashimo, Tohru Sekino, Joji Okazaki
PURPOSE: Alkali-treated titanium with nanonetwork structures (TNS) possesses good osteogenic activity; however, the resistance of this material to bacterial contamination remains inadequate. As such, TNS implants are prone to postoperative infection. In this work, we attempted to alter the biological properties of TNS by treatment with short-duration high-intensity ultraviolet (UV) irradiation. METHODS: TNS discs were treated with UV light (wavelength =254 nm, strength =100 mW/cm(2)) for 15 minutes using a UV-irradiation machine...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28720339/in%C3%A2-vitro-fit-of-cad-cam-complete-arch-screw-retained-titanium-and-zirconia-implant-prostheses-fabricated-on-4-implants
#9
Hadi Al-Meraikhi, Burak Yilmaz, Edwin McGlumphy, William Brantley, William M Johnston
STATEMENT OF PROBLEM: Computer-aided designed and computer-aided manufactured (CAD-CAM) titanium and zirconia implant-supported fixed implant prostheses on 4 implants have become popular. The precision and accuracy of their interface fit has not been widely researched. PURPOSE: The purpose of this in vitro study was to compare the marginal fit of zirconia and titanium implant-supported screw-retained CAD-CAM complete fixed dental prostheses (CFDP) fit with a standardized cast simulating the all-on-4 implant distribution...
July 15, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28719860/liposome-modified-titanium-surface-a-strategy-to-locally-deliver-bioactive-molecules
#10
Vincenzo De Leo, Monica Mattioli-Belmonte, Maria Teresa Cimmarusti, Annamaria Panniello, Manuela Dicarlo, Francesco Milano, Angela Agostiano, Elvira De Giglio, Lucia Catucci
Titanium and its alloys are widely employed materials for implants in orthopedic or dental surgery due to their mechanical properties, resistance to corrosion and osseointegration capability. However adverse reactions at the tissue/implant interface may occur, which limit the success of the osseointegration process. Therefore, different strategies have to be used to overcome these drawbacks. In this work, we developed two different liposome-based coatings on titanium surfaces as drug or bioactive molecule deposits for dental/orthopedic implant applications...
July 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28717644/optimization-of-a-functionally-graded-material-stem-in-the-femoral-component-of-a-cemented-hip-arthroplasty-influence-of-dimensionality-of-fgm
#11
Abdellah Ait Moussa, Rohan Yadav
The longevity of hip prostheses is contingent on the stability of the implant within the cavity of the femur bone. The cemented fixation was mostly adopted owing to offering the immediate stability from cement-stem and cement-bone bonding interfaces after implant surgery. Yet cement damage and stress shielding of the bone were proven to adversely affect the lifelong stability of the implant, especially among younger subjects who tend to have an active lifestyle. The geometry and material distribution of the implant can be optimized more efficiently with a three-dimensional realistic design of a functionally graded material (FGM)...
2017: Journal of Medical Engineering
https://www.readbyqxmd.com/read/28715944/comparison-of-two-different-techniques-used-for-the-maintenance-ofperi-implant-soft-tissue-health-a-pilot-randomized-clinical-trial
#12
Logien Al Ghazal, Jeffery O'Sullivan, Noel Claffey, Ioannis Polyzois
OBJECTIVES: The aim of this pilot study was to compare the effectiveness of two different methods of debridement on maintaining and improving peri-implant soft tissue health over a period of 12 months. MATERIALS AND METHODS: Twenty adult patients (25 implants) were enrolled in a randomized, single-blinded, parallel group clinical trial. All implants included showed no signs of pathologic bone loss. Patients were scheduled to be reviewed every 3 months over a 12 months period...
July 17, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28714053/the-influence-of-surface-texture-and-wettability-on-initial-bacterial-adhesion-on-titanium-and-zirconium-oxide-dental-implants
#13
Torsten Wassmann, Stefan Kreis, Michael Behr, Ralf Buergers
BACKGROUND: This study aims to investigate bacterial adhesion on different titanium and ceramic implant surfaces, to correlate these findings with surface roughness and surface hydrophobicity, and to define the predominant factor for bacterial adhesion for each material. METHODS: Zirconia and titanium specimens with different surface textures and wettability (5.0 mm in diameter, 1.0 mm in height) were prepared. Surface roughness was measured by perthometer (R a ) and atomic force microscopy, and hydrophobicity according to contact angles by computerized image analysis...
December 2017: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/28713730/application-of-orthodontic-immediate-force-on-dental-implants-histomorphologic-and-histomorphometric-assessment
#14
Mansour Rismanchian, Sayed Hamid Raji, Sayed Mohammad Razavi, Danesh Teimouri Rick, Amin Davoudi
AIMS: Application of force to implants is helpful, especially in orthodontic-implant therapies. The aim of this study was a histomorphologic and histomorphometric evaluation of peri-implant bone after immediate orthodontic and orthopedic forces comparing them with a control group. MATERIALS AND METHODS: Eighteen dental titanium implants were inserted in the premolar region of three dogs. Implants were divided into three groups: (1) group with immediate orthodontic force of 300 NC, (2) group with immediate orthopedic force of 600 NC, and (3) control group...
January 2017: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28709790/corrective-osteotomy-for-malunited-diaphyseal-forearm-fractures-using-preoperative-3-dimensional-planning-and-patient-specific-surgical-guides-and-implants
#15
Ann-Maria Byrne, Bianca Impelmans, Veronique Bertrand, Annemieke Van Haver, Frederik Verstreken
PURPOSE: Three-dimensional planning based on computed tomography images of the malunited and the mirrored contralateral forearm allows preoperative simulations of corrective osteotomies, the fabrication of patient-specific osteotomy guides, and custom-made 3-dimensional printed titanium plates. This study aims to assess the precision and clinical outcome of this technique. METHODS: This was a prospective pilot study with 5 consecutive patients. The mean age at initial injury was 11 years (range, 4-16 years), and the mean interval from the time of injury to the time of corrective surgery was 32 months (range, 7-107 months)...
July 11, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28708920/complications-and-clinical-considerations-of-the-implant-retained-zirconia-complete-arch-prosthesis-with-various-opposing-dentitions
#16
Jorge Gonzalez, Robert G Triplett
PURPOSE: To evaluate the performance of the implant-retained zirconia complete-arch prosthesis with various opposing dentitions. MATERIALS AND METHODS: The 40 patients included in this retrospective case series study were treated with one or two implant-retained zirconia complete-arch prostheses (ZIRCAP) using the Zirkonzahn protocol. Prettau zirconia frames were created with strategic cutbacks in the structure to extend zirconia incisal coverage of the esthetic anterior sextants and complete monolithic zirconia in the molar areas; subsequent layers of porcelain were applied to nonfunctional and esthetic areas...
July 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28708914/misfit-of-three-different-implant-abutment-connections-before-and-after-cyclic-load-application-an-in-vitro-study
#17
Sergio Alexandre Gehrke, Rafael Arcesio Delgado-Ruiz, Juan Carlos Prados Frutos, María Prados-Privado, Berenice Anina Dedavid, Jose Manuel Granero Marín, José Luiz Calvo Guirado
PURPOSE: This study aimed to evaluate the misfit of three different implant-abutment connections before and after cycling load. MATERIALS AND METHODS: One hundred twenty dental implants and correspondent prefabricated titanium abutments were used. Three different implant-abutment connections were evaluated: Morse taper (MT group), external hexagon (EH group), and internal hexagon (IH group). Forty implants and 40 abutments were used per group. The parameters for the mechanical evaluation were set as: 360,000 cycles, load of 150 N, and frequency of 4 Hz...
July 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28708911/peri-implant-and-paracrestal-inflammatory-biomarkers-at-failing-versus-surviving-implant-sites-in-a-beagle-dog-study
#18
Javier Montero, Fernando Aragón, Leticia A Blanco, Yasmina Guadilla, Begona García-Cenador, Antonio López-Valverde
PURPOSE: This study sought to quantify three biochemical mediators of inflammation (tumor necrosis factor alpha [TNF-α], superoxide anion [SOA], and myeloperoxidase [MPO]) by analyzing crestal (peri-implants) and paracrestal gingival biopsy samples obtained from an experimental study on beagle dogs treated with implants inserted immediately into fresh sockets with circumferential defects. MATERIALS AND METHODS: In 10 beagle dogs, 4 roughened titanium implants (3...
July 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28708907/local-application-of-growth-hormone-to-enhance-osseointegration-in-osteoporotic-bones-a-morphometric-and-densitometric-study
#19
Elena Martin-Monge, Isabel F Tresguerres, Celia Clemente, Jesús Af Tresguerres
PURPOSE: The aim of this study was to assess the effect of local application of growth hormone on osseointegration of dental implants inserted in osteoporotic bones. MATERIALS AND METHODS: Twenty female New Zealand rabbits were used in this study. Ten were ovariectomized and fed a low-calcium diet for 6 weeks, and the others remained intact. A titanium implant was inserted into each tibia, in both groups. In half of the rabbits, 2 IU of growth hormone was placed into the ostectomy prior to the implant insertion...
July 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28708905/clinical-performance-of-dental-implants-with-a-moderately-rough-tiunite-surface-a-meta-analysis-of-prospective-clinical-studies
#20
Matthias Karl, Tomas Albrektsson
PURPOSE: A moderately rough anodized titanium implant surface (TiUnite) was introduced in 2000. This review and meta-analysis aimed to assess implant survival and marginal bone level (MBL) changes documented in the literature. MATERIALS AND METHODS: Repeated literature searches on dental implants were conducted, with the final search on October 7, 2016. The inclusion criteria were: prospective study, minimum of 20 patients, at least 12 months follow-up postloading, and TiUnite implant survival reported...
July 2017: International Journal of Oral & Maxillofacial Implants
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