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https://www.readbyqxmd.com/read/28814930/comparing-lavage-of-the-peritoneal-cavity-with-lidocaine-bupivacaine-and-normal-saline-to-reduce-the-formation-of-abdominal-adhesion-bands-in-rats
#1
Hossein Parsa, Hengameh Saravani, Fatemeh Sameei-Rad, Marjan Nasiri, Zahra Farahaninik, Amirhossein Rahmani
BACKGROUND: Intra-abdominal adhesions are fibrous bands that develop after abdominal surgery or inflammation and cause mortality and morbidity following surgeries. This study aimed to assess the effects of bupivacaine, saline and two doses of lidocaine, after peritoneal lavage and to compare their effects in reducing abdominal adhesions in rat. METHODS: In a blinded, randomised, placebo-controlled clinical trial, 50 female rats were anaesthetised and the parietal peritoneum was scratched to induce punctate bleeding...
May 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28809724/comparison-of-hemostasis-times-with-a-kaolin-based-hemostatic-pad-quikclot-radial-vs-mechanical-compression-tr-band-following-transradial-access-a-pilot-prospective-study
#2
Jonathan S Roberts, Jianli Niu, Juan A Pastor-Cervantes
BACKGROUND: Hemostasis following transradial access (TRA) is usually achieved by mechanical compression. We investigated use of the QuikClot Radial hemostasis pad (Z-Medica) compared with the TR Band (Terumo Medical) to shorten hemostasis after TRA. METHODS: Thirty patients undergoing TRA coronary angiography and/or percutaneous coronary intervention were randomized into three cohorts post TRA: 10 patients received mechanical compression with the TR Band, 10 patients received 30 min of compression with the QuikClot Radial pad, and 10 patients received 60 min of compression with the QuikClot Radial pad...
August 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28800575/disruption-of-frontal-parietal-connectivity-during-conscious-sedation-by-propofol-administration
#3
Pil-Jong Kim, Hong-Gee Kim, Gyu-Jeong Noh, Yong-Seo Koo, Teo Jeon Shin
The sedative state is a transitional state from wakefulness to general anesthesia. However, little is understood regarding the mechanism of conscious sedation, different from general anesthesia while maintaining wakefulness. In this study, we aimed to investigate changes in functional connectivity of the parietal-frontal network, implicated in wakefulness during conscious sedation induced by propofol infusion. The electroencephalography was obtained at the frontal and parietal areas of adult volunteers who maintain wakefulness during low-dose propofol infusion (1...
August 10, 2017: Neuroreport
https://www.readbyqxmd.com/read/28796750/in-vivo-electron-paramagnetic-resonance-tooth-dosimetry-dependence-of-radiation-induced-signal-amplitude-on-the-enamel-thickness-and-surface-area-of-ex-vivo-human-teeth
#4
Michitaka Umakoshi, Ichiro Yamaguchi, Hiroshi Hirata, Naoki Kunugita, Benjamin B Williams, Harold M Swartz, Minoru Miyake
In vivo L-band electron paramagnetic resonance tooth dosimetry is a newly developed and very promising method for retrospective biodosimetry in individuals who may have been exposed to significant levels of ionizing radiation. The present study aimed to determine the relationships among enamel thickness, enamel area, and measured electron paramagnetic resonance signal amplitude with a view to improve the quantitative accuracy of the dosimetry technique. Ten isolated incisors were irradiated using well-characterized doses, and their radiation-induced electron paramagnetic resonance signals were measured...
August 7, 2017: Health Physics
https://www.readbyqxmd.com/read/28791082/protective-effect-of-nigella-sativa-oil-on-acoustic-trauma-induced-hearing-loss-in-rats
#5
Belde Culhaoglu, Selim S Erbek, Seyra Erbek, Evren Hizal
Acoustic trauma is a common reason for hearing loss. Different agents are used to prevent the harmful effect of acoustic trauma on hearing. The aim of this study was to evaluate the potential preventive effect of Nigella sativa (black cumin) oil in acoustic trauma. Our experimental study was conducted with 20 Sprague Downey female rats (mean age, 12 months; mean weight 250 g). All of the procedures were held under general anesthesia. Following otoscopic examinations, baseline-hearing thresholds were obtained using auditory brainstem responses (ABR)...
July 18, 2017: Audiology Research
https://www.readbyqxmd.com/read/28771082/effects-of-bmi-on-bone-loading-due-to-physical-activity
#6
Tina Smith, Sue Reeves, Lewis Halsye, Jörg Huber, Jin Luo
The aim of the current study was to compare bone loading due to physical activity between lean and, overweight and obese individuals. Fifteen participants (lower BMI group: BMI < 25 kg/m(2), n=7; higher BMI group: 25 kg/m(2) < BMI < 36.35 kg/m(2), n=8) wore a tri-axial accelerometer on one day to collect data for the calculation of bone loading. The International Physical Activity Questionnaire (short form) was used to measure time spent at different physical activity levels. Daily step counts were measured using a pedometer...
August 3, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/28762049/biogenic-synthesis-of-gold-nanoparticles-from-terminalia-arjuna-bark-extract-assessment-of-safety-aspects-and-neuroprotective-potential-via-antioxidant-anticholinesterase-and-antiamyloidogenic-effects
#7
Natarajan Suganthy, Vijayan Sri Ramkumar, Arivalagan Pugazhendhi, Giovanni Benelli, Govindaraju Archunan
The development of neuroprotective drugs through eco-friendly production routes is a major challenge for current pharmacology. The present study was carried out to synthesize gold nanoparticles (AuNPs) through biogenic route using ethanolic bark extract of Terminalia arjuna, a plant of high interest in Asian traditional medicine, and to evaluate its neuroprotective effects. The synthesized AuNPs were characterized by UV-Vis spectroscopy, FTIR spectroscopy, XRD, FESEM, EDX, HRTEM, DLS, and zeta potential analyses...
July 31, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28758200/endoscopic-screening-for-synchronous-esophageal-neoplasia-among-patients-with-incident-head-and-neck-cancer-prevalence-risk-factors-and-outcomes
#8
Yao-Kuang Wang, Yun-Shiuan Chuang, Tzung-Shiun Wu, Ka-Wo Lee, Che-Wei Wu, Hsiang-Chen Wang, Chie-Tong Kuo, Chien-Hung Lee, Wen-Rei Kuo, Chung-Ho Chen, Deng-Chyang Wu, I-Chen Wu
Esophageal squamous-cell neoplasia (ESCN) is a common second primary neoplasia found in patients with head-and-neck squamous-cell carcinoma (HNSCC). This study sought to identify the risk factors for synchronous ESCN and how they influence survival in HNSCC patient. 815 incident HNSCC patients were prospectively recruited for endoscopy screening for ESCN using white-light imaging, narrow-band imaging, Lugol chromoendoscopy, and pathological confirmation. Associated lifestyle and clinicopathological data were collected...
July 30, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28754611/transdermal-delivery-of-gentamicin-using-dissolving-microneedle-arrays-for-potential-treatment-of-neonatal-sepsis
#9
Patricia González-Vázquez, Eneko Larrañeta, Maelíosa T C McCrudden, Courtney Jarrahian, Annie Rein-Weston, Manjari Quintanar-Solares, Darin Zehrung, Helen McCarthy, Aaron J Courtenay, Ryan F Donnelly
Neonatal infections are a leading cause of childhood mortality in low-resource settings. World Health Organization guidelines for outpatient treatment of possible serious bacterial infection (PSBI) in neonates and young infants when referral for hospital treatment is not feasible include intramuscular gentamicin (GEN) and oral amoxicillin. GEN is supplied as an aqueous solution of gentamicin sulphate in vials or ampoules and requires health care workers to be trained in dose calculation or selection of an appropriate dose based on the patient's weight band and to have access to safe injection supplies and appropriate sharps disposal...
July 25, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28753197/corrigendum-low-dose-add-on-memantine-treatment-may-improve-cognitive-performance-and-self-reported-health-conditions-in-opioid-dependent-patients-undergoing-methadone-maintenance-therapy
#10
Yun-Hsuan Chang, Shiou-Lan Chen, Sheng-Yu Lee, Po See Chen, Tzu-Yun Wang, I Hui Lee, Kao Chin Chen, Yen Kuang Yang, Jau-Shyong Hong, Ru-Band Lu
This corrects the article DOI: 10.1038/srep09708.
June 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28750281/heteroleptic-monometallic-and-trimetallic-ruthenium-ii-complexes-incorporating-a-%C3%AF-extended-dipyrrin-ligand-light-activated-reactions-with-the-a549-lung-cancer-cell-line
#11
Shawn Swavey, Krista Morford, Max Tsao, Kristen Comfort, Mary Kate Kilroy
A heteroleptic monometallic ruthenium(II) and a heteroleptic trimetallic ruthenium(II) complex have been synthesized and characterized. Both complexes have an overall 3+ charge, with the charge density greater for the monometallic complex. The electronic spectra of the monometallic ruthenium(II) complex exhibits intense π-π* transitions associated with the bipyridyl groups along with overlapping metal to ligand charge transfer (MLCT) and ligand centered π-π* transitions ranging from 520nm to approximately 600nm...
July 18, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28743619/organ-and-effective-doses-from-paediatric-interventional-cardiology-procedures-in-chile
#12
Carlos Ubeda, Patricia Miranda, Eliseo Vano, Diego Nocetti, Carlos Manterola
The aim of this study was to present the results of organ and effective doses for paediatric patients for different types of interventional cardiology procedures for age and weight groups, derived from a patient dosimetry pilot programme carried out in Chile, under the auspices of the International Atomic Energy Agency. Over seven years, a retrospective collection of demographic and patient dose data was obtained: age, gender, weight, height, number of cine series, total number of cine frames, fluoroscopy time, dose-area product (DAP) and cumulative dose at patient entrance reference point...
July 22, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28740865/superconductivity-across-lifshitz-transition-and-anomalous-insulating-state-in-surface-k-dosed-li0-8fe0-2oh-fese
#13
Mingqiang Ren, Yajun Yan, Xiaohai Niu, Ran Tao, Die Hu, Rui Peng, Binping Xie, Jun Zhao, Tong Zhang, Dong-Lai Feng
In iron-based superconductors, understanding the relation between superconductivity and electronic structure upon doping is crucial for exploring the pairing mechanism. Recently, it was found that, in iron selenide (FeSe), enhanced superconductivity (Tc of more than 40 K) can be achieved via electron doping, with the Fermi surface only comprising M-centered electron pockets. By using surface K dosing, scanning tunneling microscopy/spectroscopy, and angle-resolved photoemission spectroscopy, we studied the electronic structure and superconductivity of (Li0...
July 2017: Science Advances
https://www.readbyqxmd.com/read/28739134/nmda-receptor-modulation-by-dextromethorphan-and-acute-stress-selectively-alters-electroencephalographic-indicators-of-partial-report-processing
#14
Lisa J Weckesser, Sören Enge, Philipp Riedel, Clemens Kirschbaum, Robert Miller
Proceeding from a biophysical network model, the present study hypothesized that glutamatergic neurotransmission across the NMDA receptor (NMDAR) plays a key role in visual perception and its modulation by acute stress. To investigate these hypotheses, behavioral and electroencephalographic (EEG) indicators of partial report task processing were assessed in twenty-four healthy young men who randomly received a non-competitive NMDAR antagonist (0.8 mg/kg dextromethorphan, DXM) or a placebo, and concurrently accomplished a stress-induction (MAST) or control protocol in three consecutive sessions...
July 21, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28713364/immunomodulatory-activities-of-a-fungal-protein-extracted-from-hericium-erinaceus-through-regulating-the-gut-microbiota
#15
Chen Diling, Zheng Chaoqun, Yang Jian, Li Jian, Su Jiyan, Xie Yizhen, Lai Guoxiao
A single-band protein (HEP3) was isolated from Hericium erinaceus using a chemical separation combined with pharmacodynamic evaluation methods. This protein exhibited immunomodulatory activity in lipopolysaccharide-activated RAW 264.7 macrophages by decreasing the overproduction of tumor necrosis factor-α, interleukin (IL)-1β, and IL-6, and downregulating the expression of inducible nitric oxide synthase and nuclear factor-κB p65. Further researches revealed that HEP3 could improve the immune system via regulating the composition and metabolism of gut microbiota to activate the proliferation and differentiation of T cells, stimulate the intestinal antigen-presenting cells in high-dose cyclophosphamide-induced immunotoxicity in mice, and play a prebiotic role in the case of excessive antibiotics in inflammatory bowel disease model mice...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28709427/investigation-of-irradiated-volume-in-linac-based-brain-hypo-fractionated-stereotactic-radiotherapy
#16
Mark Ruschin, Arjun Sahgal, Hany Soliman, Sten Myrehaug, May Tsao, Collins Yeboah, Arman Sarfehnia, Brige Chugh, Alex Kiss, Young Lee
BACKGROUND: Emerging techniques such as brain hypo-fractionated radiotherapy (HF-RT) involve complex cases with limited guidelines for plan quality and normal tissue tolerances. The purpose of the present study was to statistically parameterize irradiated volume independently of dose prescription, or margin to determine what spread in achievable irradiated volume one may expect for a given case. METHODS: We defined EXT as the total tissue within the external contour of the patient (including the target) and we defined BMP as the contour of the brain minus PTV...
July 14, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28703320/5-aminolevulinic-acid-patch-pdt-in-the-treatment-of-actinic-cheilitis
#17
Sonja Radakovic, Adrian Tanew
BACKGROUND: Actinic cheilitis (AC) is a common disease caused by chronic ultraviolet exposure. OBJECTIVE: Alacare is a self-adhesive, skin coloured 5-aminolaevulinic acid (ALA) patch that has been developed for the treatment of mild to moderate actinic keratosis (AK). Considering the good results in the treatment of AK, the standardized delivery of ALA and the simple application Alacare patch PDT appears as an interesting treatment option for AC. METHODS: We retrospectively assessed the efficacy, tolerability and cosmetic outcome of Alacare patch PDT in eleven patients with AC...
July 13, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/28702111/innate-function-of-house-dust-mite-allergens-robust-enzymatic-degradation-of-extracellular-matrix-at-elevated-ph
#18
Kumiko Oida, Lukas Einhorn, Ina Herrmann, Lucia Panakova, Yvonne Resch, Susanne Vrtala, Gerlinde Hofstetter, Akane Tanaka, Hiroshi Matsuda, Erika Jensen-Jarolim
BACKGROUND: Exposure to the house dust mite Dermatophagoides pteronyssinus (D.p.) increases the risk for developing allergic diseases in humans and their best friends, the dogs. Here, we explored whether this allergenic mite via its enzymes may impact the cutaneous extracellular matrix (ECM), which critically determines epithelial barrier integrity both structurally and functionally. METHODS: Two extracts obtained from either dust-purified or cultured D.p. bodies were used in the present study...
2017: World Allergy Organization Journal
https://www.readbyqxmd.com/read/28701785/possible-electric-field-induced-indirect-to-direct-band-gap-transition-in-mose2
#19
B S Kim, W S Kyung, J J Seo, J Y Kwon, J D Denlinger, C Kim, S R Park
Direct band-gap semiconductors play the central role in optoelectronics. In this regard, monolayer (ML) MX2 (M = Mo, W; X = S, Se) has drawn increasing attention due to its novel optoelectronic properties stemming from the direct band-gap and valley degeneracy. Unfortunately, the more practically usable bulk and multilayer MX2 have indirect-gaps. It is thus highly desired to turn bulk and multilayer MX2 into direct band-gap semiconductors by controlling external parameters. Here, we report angle-resolved photoemission spectroscopy (ARPES) results from Rb dosed MoSe2 that suggest possibility for electric field induced indirect to direct band-gap transition in bulk MoSe2...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28694800/bacterial-survival-under-extreme-uv-radiation-a-comparative-proteomics-study-of-rhodobacter-sp-isolated-from-high-altitude-wetlands-in-chile
#20
Vilma Pérez, Martha Hengst, Lenka Kurte, Cristina Dorador, Wade H Jeffrey, Ruddy Wattiez, Veronica Molina, Sabine Matallana-Surget
Salar de Huasco, defined as a polyextreme environment, is a high altitude saline wetland in the Chilean Altiplano (3800 m.a.s.l.), permanently exposed to the highest solar radiation doses registered in the world. We present here the first comparative proteomics study of a photoheterotrophic bacterium, Rhodobacter sp., isolated from this remote and hostile habitat. We developed an innovative experimental approach using different sources of radiation (in situ sunlight and UVB lamps), cut-off filters (Mylar, Lee filters) and a high-throughput, label-free quantitative proteomics method to comprehensively analyze the effect of seven spectral bands on protein regulation...
2017: Frontiers in Microbiology
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