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https://www.readbyqxmd.com/read/29453891/an-investigation-of-an-open-access-model-for-scaling-up-methadone-maintenance-treatment
#1
Lynn M Madden, Scott O Farnum, Kathryn F Eggert, Andrew R Quanbeck, Robert Freeman, Samuel A Ball, Richard S Schottenfeld, Julia M Shi, Mary Ellen Savage, Declan T Barry
AIMS: To retrospectively examine patient and programmatic outcomes following the development and implementation of an "open-access" model in which prospective patients were enrolled rapidly in methadone maintenance treatment, irrespective of ability to pay, and provided real-time access to multiple voluntary treatment options. DESIGN: Medical and administrative records were abstracted to compare data for one year before and 9 years after initiating the implementation of an open-access treatment model in May 2007...
February 17, 2018: Addiction
https://www.readbyqxmd.com/read/29450793/the-quality-of-response-time-data-inference-a-blinded-collaborative-assessment-of-the-validity-of-cognitive-models
#2
Gilles Dutilh, Jeffrey Annis, Scott D Brown, Peter Cassey, Nathan J Evans, Raoul P P P Grasman, Guy E Hawkins, Andrew Heathcote, William R Holmes, Angelos-Miltiadis Krypotos, Colin N Kupitz, Fábio P Leite, Veronika Lerche, Yi-Shin Lin, Gordon D Logan, Thomas J Palmeri, Jeffrey J Starns, Jennifer S Trueblood, Leendert van Maanen, Don van Ravenzwaaij, Joachim Vandekerckhove, Ingmar Visser, Andreas Voss, Corey N White, Thomas V Wiecki, Jörg Rieskamp, Chris Donkin
Most data analyses rely on models. To complement statistical models, psychologists have developed cognitive models, which translate observed variables into psychologically interesting constructs. Response time models, in particular, assume that response time and accuracy are the observed expression of latent variables including 1) ease of processing, 2) response caution, 3) response bias, and 4) non-decision time. Inferences about these psychological factors hinge upon the validity of the models' parameters...
February 15, 2018: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/29449510/winter-color-polymorphisms-identify-global-hot-spots-for-evolutionary-rescue-from-climate-change
#3
L Scott Mills, Eugenia V Bragina, Alexander V Kumar, Marketa Zimova, Diana J R Lafferty, Jennifer Feltner, Brandon M Davis, Klaus Hackländer, Paulo C Alves, Jeffrey M Good, José Melo-Ferreira, Andreas Dietz, Alexei V Abramov, Natalia Lopatina, Kairsten Fay
Maintenance of biodiversity in a rapidly changing climate will depend on the efficacy of evolutionary rescue, whereby population declines due to abrupt environmental change are reversed by shifts in genetically driven adaptive traits. However, a lack of traits known to be under direct selection by anthropogenic climate change has limited the incorporation of evolutionary processes into global conservation efforts. In 21 vertebrate species, some individuals undergo a seasonal color molt from summer brown to winter white as camouflage against snow, while other individuals remain brown...
February 15, 2018: Science
https://www.readbyqxmd.com/read/29448160/multi-plane-multi-joint-lower-extremity-support-moments-during-a-rapid-deceleration-task-implications-for-knee-loading
#4
Jeffery T Podraza, Scott C White, Dan K Ramsey
The principle of lower limb support, and the contribution of hip, knee and ankle moments to an overall limb support strategy for an impact-like, rapid deceleration movement may help explain individual moment magnitude changes, thereby providing insight into how injury might occur or be avoided. Twenty subjects performed single limb, impact-like, deceleration landings at three different knee flexion angles in the range of 0-25, 25-50 and 50-75°. Kinematic and kinetic measures identified hip, knee and ankle moment contribution to limb support moments (LSMs) in three planes...
February 12, 2018: Human Movement Science
https://www.readbyqxmd.com/read/29447061/models-to-predict-hepatitis-b-virus-infection-among-patients-with-cancer-undergoing-systemic-anticancer-therapy-a-prospective-cohort-study
#5
Jessica P Hwang, Anna S Lok, Michael J Fisch, Scott B Cantor, Andrea Barbo, Heather Y Lin, Jessica T Foreman, John M Vierling, Harrys A Torres, Bruno P Granwehr, Ethan Miller, Cathy Eng, George R Simon, Sairah Ahmed, Alessandra Ferrajoli, Jorge Romaguera, Maria E Suarez-Almazor
Purpose Most patients with cancer are not screened for hepatitis B virus (HBV) infection before undergoing anticancer therapy, and optimal screening strategies are unknown. We sought to develop selective HBV screening strategies for patients who require systemic anticancer therapy. Methods This prospective cohort study included adults age ≥ 18 years with solid or hematologic malignancies who received systemic anticancer therapy at a comprehensive cancer center during 2013 and 2014. Patients underwent hepatitis B surface antigen, hepatitis B core antibody, and hepatitis B surface antibody testing, and completed a 19-question modified Centers for Disease Control and Prevention (CDC) HBV survey...
February 15, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29444914/palatal-prolapse-as-a-signature-of-expiratory-flow-limitation-and-inspiratory-palatal-collapse-in-patients-with-obstructive-sleep-apnoea
#6
Ali Azarbarzin, Scott A Sands, Melania Marques, Pedro R Genta, Luigi Taranto-Montemurro, Ludovico Messineo, David P White, Andrew Wellman
In some individuals with obstructive sleep apnoea (OSA), the palate prolapses into the velopharynx during expiration, limiting airflow through the nose or shunting it out of the mouth. We hypothesised that this phenomenon causes expiratory flow limitation (EFL) and is associated with inspiratory "isolated" palatal collapse. We also wanted to provide a robust noninvasive means to identify this mechanism of obstruction.Using natural sleep endoscopy, 1211 breaths from 22 OSA patients were scored as having or not having palatal prolapse...
February 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29434027/genome-sequencing-identifies-somatic-braf-duplication-c-1794_1796duptac-p-thr599dup-in-pediatric-patient-with-low-grade-ganglioglioma
#7
Katherine E Miller, Benjamin Kelly, James Fitch, Nicole Ross, Matthew R Avenarius, Elizabeth Varga, Daniel C Koboldt, Daniel R Boue, Vincent Magrini, Scott L Coven, Jonathan L Finlay, Catherine E Cottrell, Peter White, Julie M Gastier-Foster, Richard K Wilson, Jeffrey Leonard, Elaine R Mardis
Gangliogliomas [WHO grade I] are rare tumors affecting the central nervous system and are most frequently observed in children. Genome sequencing of tumors is being utilized at an increasing rate in both research and clinical settings to characterize the genetic factors that drive tumorigenesis. Here, we report a rare BRAF somatic mutation (NM_004333.4:c.1794_1796dupTAC; p.Thr599dup) in the tumor genome from a pediatric patient in her late teens, who was initially diagnosed with low-grade ganglioglioma at age 13...
February 6, 2018: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/29423513/association-of-contact-lens-adherence-with-visual-outcome-in-the-infant-aphakia-treatment-study-a-secondary-analysis-of-a-randomized-clinical-trial
#8
Caroline H Cromelin, Carolyn Drews-Botsch, Buddy Russell, Scott R Lambert
Importance: Although contact lenses have been used for decades to optically correct eyes in children after cataract surgery, there has never been a prospective study looking at contact lens adherence in children with aphakia, to our knowledge. Objective: To evaluate contact lens adherence and its association with visual outcome in a cohort of children treated for unilateral cataract surgery. Design, Setting, and Participants: Secondary analysis of a multicenter randomized clinical trial of 57 infants born from August 22, 2004, to April 25, 2008, who were randomized to 1 of 2 treatments and followed up to age 5 years...
February 8, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29422052/high-willingness-to-use-rapid-fentanyl-test-strips-among-young-adults-who-use-drugs
#9
Maxwell S Krieger, Jesse L Yedinak, Jane A Buxton, Mark Lysyshyn, Edward Bernstein, Josiah D Rich, Traci C Green, Scott E Hadland, Brandon D L Marshall
BACKGROUND: Synthetic opioid overdose mortality among young adults has risen more than 300% in the USA since 2013, primarily due to the contamination of heroin and other drugs with illicitly manufactured fentanyl. Rapid test strips, which can be used to detect the presence of fentanyl in drug samples (before use) or urine (after use), may help inform people about their exposure risk. The purpose of this study was to determine whether young adults who use drugs were willing to use rapid test strips as a harm reduction intervention to prevent overdose...
February 8, 2018: Harm Reduction Journal
https://www.readbyqxmd.com/read/29421019/access-to-routine-care-and-risks-for-30-day-readmission-in-patients-with-cardiovascular-disease
#10
Matthew E Dupre, Hanzhang Xu, Bradi B Granger, Scott M Lynch, Alicia Nelson, Erik Churchill, Janese M Willis, Lesley H Curtis, Eric D Peterson
BACKGROUND: Studies have shown that access to routine medical care is associated with the prevention, diagnosis, and treatment of chronic diseases. However, studies have not examined whether patient-reported difficulties in access to care are associated with rehospitalization in patients with cardiovascular disease. METHODS: Electronic medical records and a standardized survey were used to examine cardiovascular patients admitted to a large medical center from January 1, 2015 through January 10, 2017 (n=520)...
February 2018: American Heart Journal
https://www.readbyqxmd.com/read/29420459/vital-signs-asthma-in-children-united-states-2001-2016
#11
Hatice S Zahran, Cathy M Bailey, Scott A Damon, Paul L Garbe, Patrick N Breysse
BACKGROUND: Asthma is the most common chronic lung disease of childhood, affecting approximately 6 million children in the United States. Although asthma cannot be cured, most of the time, asthma symptoms can be controlled by avoiding or reducing exposure to asthma triggers (allergens and irritants) and by following recommendations for asthma education and appropriate medical care. METHODS: CDC analyzed asthma data from the 2001-2016 National Health Interview Survey for children aged 0-17 years to examine trends and demographic differences in health outcomes and health care use...
February 9, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29413686/determinants-and-prognostic-value-of-quality-of-life-in-patients-with-pancreatic-ductal-adenocarcinoma
#12
Yang Deng, Huakang Tu, Jeanne A Pierzynski, Ethan D Miller, Xiangjun Gu, Maosheng Huang, David W Chang, Yuanqing Ye, Michelle A T Hildebrandt, Alison P Klein, Ren Zhao, Scott M Lippman, Xifeng Wu
BACKGROUND: Quality of life (QOL) is impaired in pancreatic cancer patients. Our aim was to investigate the determinants and prognostic value of QOL after diagnosis in a hospital-based cohort of racially/ethnically diverse patients with pancreatic ductal adenocarcinoma (PDAC). PATIENTS AND METHODS: QOL was prospectively assessed using the Short Form-12 in 2478 PDAC patients. The Physical Component Summary (PCS) and Mental Component Summary (MCS) were categorised into tertiles based on their distribution...
February 1, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29411606/detection-and-sourcing-of-gluten-in-grain-with-multiple-floating-gate-transistor-biosensors
#13
Scott P White, C Daniel Frisbie, Kevin D Dorfman
We report a chemically tunable electronic sensor for quantitation of gluten based on a floating-gate transistor (FGT) architecture. The FGTs are fabricated in parallel and each one is functionalized with a different chemical moiety designed to preferentially bind a specific grain source of gluten. The resulting set of FGT sensors can detect both wheat and barley gluten below the gluten-free limit of 20 ppm (w/w) while providing a source-dependent signature for improved accuracy. This label-free transduction method does not require any secondary binding events, resulting in a ca...
February 7, 2018: ACS Sensors
https://www.readbyqxmd.com/read/29410486/the-energy-landscape-of-neurophysiological-activity-implicit-in-brain-network-structure
#14
Shi Gu, Matthew Cieslak, Benjamin Baird, Sarah F Muldoon, Scott T Grafton, Fabio Pasqualetti, Danielle S Bassett
A critical mystery in neuroscience lies in determining how anatomical structure impacts the complex functional dynamics of the brain. How does large-scale brain circuitry constrain states of neuronal activity and transitions between those states? We address these questions using a maximum entropy model of brain dynamics informed by white matter tractography. We demonstrate that the most probable brain states - characterized by minimal energy - display common activation profiles across brain areas: local spatially-contiguous sets of brain regions reminiscent of cognitive systems are co-activated frequently...
February 6, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29410205/spatial-coherence-of-oriented-white-matter-microstructure-applications-to-white-matter-regions-associated-with-genetic-similarity
#15
Haraldur T Hallgrímsson, Matthew Cieslak, Luca Foschini, Scott Grafton, Ambuj K Singh
We present a method to discover differences between populations with respect to the spatial coherence of their oriented white matter microstructure in arbitrarily shaped white matter regions. This method is applied to diffusion MRI scans of a subset of the Human Connectome Project dataset: 57 pairs of monozygotic and 52 pairs of dizygotic twins. After controlling for morphological similarity between twins, we identify 3.7% of all white matter as being associated with genetic similarity (35.1 k voxels, p<10-4, false discovery rate 1...
February 1, 2018: NeuroImage
https://www.readbyqxmd.com/read/29410046/systems-biology-and-in-vitro-validation-identifies-fam129a-as-asthma-steroid-response-modulator
#16
Michael J McGeachie, George L Clemmer, Boris Hayete, Heming Xing, Karl Runge, Ann Chen Wu, Xiaofeng Jiang, Quan Lu, Bruce Church, Iya Khalil, Kelan Tantisira, Scott Weiss
BACKGROUND: Variation in response to the most commonly used class of asthma controller medication, inhaled corticosteroids (ICS), presents a serious challenge in asthma management, particularly for steroid-resistant patients who display little or no response to treatment. OBJECTIVE: We applied a systems-biology approach to primary clinical and genomic data to identify and validate genes that modulate steroid response in children with asthma. METHODS: We selected 104 ICS-treated asthmatic non-Hispanic white children and determined a Steroid Responsiveness Endophenotype (SRE) using observations of six clinical measures over four years...
January 30, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29401331/supraclavicular-thoracic-outlet-decompression-in-the-high-performance-military-population
#17
Joseph M White, Andrew J Soo Hoo, Scott R Golarz
Background: Neurogenic thoracic outlet syndrome (nTOS) is a relatively common disorder and often affects younger, physically active populations. The modern American military is a population at risk for the development of nTOS given the intense physical training requirements. The purpose of this study is to determine functional recovery in the active duty military population resulting in full, unrestricted return-to-duty status following supraclavicular thoracic outlet decompression with partial first rib resection, partial anterior scalenectomy, and brachial plexus neurolysis...
January 1, 2018: Military Medicine
https://www.readbyqxmd.com/read/29400511/first-search-for-nontensorial-gravitational-waves-from-known-pulsars
#18
B P Abbott, R Abbott, T D Abbott, F Acernese, K Ackley, C Adams, T Adams, P Addesso, R X Adhikari, V B Adya, C Affeldt, M Afrough, B Agarwal, M Agathos, K Agatsuma, N Aggarwal, O D Aguiar, L Aiello, A Ain, P Ajith, G Allen, A Allocca, P A Altin, A Amato, A Ananyeva, S B Anderson, W G Anderson, S Antier, S Appert, K Arai, M C Araya, J S Areeda, N Arnaud, K G Arun, S Ascenzi, G Ashton, M Ast, S M Aston, P Astone, P Aufmuth, C Aulbert, K AultONeal, A Avila-Alvarez, S Babak, P Bacon, M K M Bader, S Bae, P T Baker, F Baldaccini, G Ballardin, S W Ballmer, S Banagiri, J C Barayoga, S E Barclay, B C Barish, D Barker, F Barone, B Barr, L Barsotti, M Barsuglia, D Barta, J Bartlett, I Bartos, R Bassiri, A Basti, J C Batch, C Baune, M Bawaj, M Bazzan, B Bécsy, C Beer, M Bejger, I Belahcene, A S Bell, B K Berger, G Bergmann, C P L Berry, D Bersanetti, A Bertolini, J Betzwieser, S Bhagwat, R Bhandare, I A Bilenko, G Billingsley, C R Billman, J Birch, R Birney, O Birnholtz, S Biscans, A Bisht, M Bitossi, C Biwer, M A Bizouard, J K Blackburn, J Blackman, C D Blair, D G Blair, R M Blair, S Bloemen, O Bock, N Bode, M Boer, G Bogaert, A Bohe, F Bondu, R Bonnand, B A Boom, R Bork, V Boschi, S Bose, Y Bouffanais, A Bozzi, C Bradaschia, P R Brady, V B Braginsky, M Branchesi, J E Brau, T Briant, A Brillet, M Brinkmann, V Brisson, P Brockill, J E Broida, A F Brooks, D A Brown, D D Brown, N M Brown, S Brunett, C C Buchanan, A Buikema, T Bulik, H J Bulten, A Buonanno, D Buskulic, C Buy, R L Byer, M Cabero, L Cadonati, G Cagnoli, C Cahillane, J Calderón Bustillo, T A Callister, E Calloni, J B Camp, M Canepa, P Canizares, K C Cannon, H Cao, J Cao, C D Capano, E Capocasa, F Carbognani, S Caride, M F Carney, J Casanueva Diaz, C Casentini, S Caudill, M Cavaglià, F Cavalier, R Cavalieri, G Cella, C B Cepeda, L Cerboni Baiardi, G Cerretani, E Cesarini, S J Chamberlin, M Chan, S Chao, P Charlton, E Chassande-Mottin, D Chatterjee, B D Cheeseboro, H Y Chen, Y Chen, H-P Cheng, A Chincarini, A Chiummo, T Chmiel, H S Cho, M Cho, J H Chow, N Christensen, Q Chu, A J K Chua, S Chua, A K W Chung, S Chung, G Ciani, R Ciolfi, C E Cirelli, A Cirone, F Clara, J A Clark, F Cleva, C Cocchieri, E Coccia, P-F Cohadon, A Colla, C G Collette, L R Cominsky, M Constancio, L Conti, S J Cooper, P Corban, T R Corbitt, K R Corley, N Cornish, A Corsi, S Cortese, C A Costa, M W Coughlin, S B Coughlin, J-P Coulon, S T Countryman, P Couvares, P B Covas, E E Cowan, D M Coward, M J Cowart, D C Coyne, R Coyne, J D E Creighton, T D Creighton, J Cripe, S G Crowder, T J Cullen, A Cumming, L Cunningham, E Cuoco, T Dal Canton, S L Danilishin, S D'Antonio, K Danzmann, A Dasgupta, C F Da Silva Costa, V Dattilo, I Dave, M Davier, D Davis, E J Daw, B Day, S De, D DeBra, J Degallaix, M De Laurentis, S Deléglise, W Del Pozzo, T Denker, T Dent, V Dergachev, R De Rosa, R T DeRosa, R DeSalvo, J Devenson, R C Devine, S Dhurandhar, M C Díaz, L Di Fiore, M Di Giovanni, T Di Girolamo, A Di Lieto, S Di Pace, I Di Palma, F Di Renzo, Z Doctor, V Dolique, F Donovan, K L Dooley, S Doravari, I Dorrington, R Douglas, M Dovale Álvarez, T P Downes, M Drago, R W P Drever, J C Driggers, Z Du, M Ducrot, J Duncan, S E Dwyer, T B Edo, M C Edwards, A Effler, H-B Eggenstein, P Ehrens, J Eichholz, S S Eikenberry, R A Eisenstein, R C Essick, Z B Etienne, T Etzel, M Evans, T M Evans, M Factourovich, V Fafone, H Fair, S Fairhurst, X Fan, S Farinon, B Farr, W M Farr, E J Fauchon-Jones, M Favata, M Fays, H Fehrmann, J Feicht, M M Fejer, A Fernandez-Galiana, I Ferrante, E C Ferreira, F Ferrini, F Fidecaro, I Fiori, D Fiorucci, R P Fisher, R Flaminio, M Fletcher, H Fong, P W F Forsyth, S S Forsyth, J-D Fournier, S Frasca, F Frasconi, Z Frei, A Freise, R Frey, V Frey, E M Fries, P Fritschel, V V Frolov, P Fulda, M Fyffe, H Gabbard, M Gabel, B U Gadre, S M Gaebel, J R Gair, L Gammaitoni, M R Ganija, S G Gaonkar, F Garufi, S Gaudio, G Gaur, V Gayathri, N Gehrels, G Gemme, E Genin, A Gennai, D George, J George, L Gergely, V Germain, S Ghonge, Abhirup Ghosh, Archisman Ghosh, S Ghosh, J A Giaime, K D Giardina, A Giazotto, K Gill, L Glover, E Goetz, R Goetz, S Gomes, G González, J M Gonzalez Castro, A Gopakumar, M L Gorodetsky, S E Gossan, M Gosselin, R Gouaty, A Grado, C Graef, M Granata, A Grant, S Gras, C Gray, G Greco, A C Green, P Groot, H Grote, S Grunewald, P Gruning, G M Guidi, X Guo, A Gupta, M K Gupta, K E Gushwa, E K Gustafson, R Gustafson, B R Hall, E D Hall, G Hammond, M Haney, M M Hanke, J Hanks, C Hanna, O A Hannuksela, J Hanson, T Hardwick, J Harms, G M Harry, I W Harry, M J Hart, C-J Haster, K Haughian, J Healy, A Heidmann, M C Heintze, H Heitmann, P Hello, G Hemming, M Hendry, I S Heng, J Hennig, J Henry, A W Heptonstall, M Heurs, S Hild, D Hoak, D Hofman, K Holt, D E Holz, P Hopkins, C Horst, J Hough, E A Houston, E J Howell, Y M Hu, E A Huerta, D Huet, B Hughey, S Husa, S H Huttner, T Huynh-Dinh, N Indik, D R Ingram, R Inta, G Intini, H N Isa, J-M Isac, M Isi, B R Iyer, K Izumi, T Jacqmin, K Jani, P Jaranowski, S Jawahar, F Jiménez-Forteza, W W Johnson, D I Jones, R Jones, R J G Jonker, L Ju, J Junker, C V Kalaghatgi, V Kalogera, S Kandhasamy, G Kang, J B Kanner, S Karki, K S Karvinen, M Kasprzack, M Katolik, E Katsavounidis, W Katzman, S Kaufer, K Kawabe, F Kéfélian, D Keitel, A J Kemball, R Kennedy, C Kent, J S Key, F Y Khalili, I Khan, S Khan, Z Khan, E A Khazanov, N Kijbunchoo, Chunglee Kim, J C Kim, W Kim, W S Kim, Y-M Kim, S J Kimbrell, E J King, P J King, R Kirchhoff, J S Kissel, L Kleybolte, S Klimenko, P Koch, S M Koehlenbeck, S Koley, V Kondrashov, A Kontos, M Korobko, W Z Korth, I Kowalska, D B Kozak, C Krämer, V Kringel, B Krishnan, A Królak, G Kuehn, P Kumar, R Kumar, S Kumar, L Kuo, A Kutynia, S Kwang, B D Lackey, K H Lai, M Landry, R N Lang, J Lange, B Lantz, R K Lanza, A Lartaux-Vollard, P D Lasky, M Laxen, A Lazzarini, C Lazzaro, P Leaci, S Leavey, C H Lee, H K Lee, H M Lee, H W Lee, K Lee, J Lehmann, A Lenon, M Leonardi, N Leroy, N Letendre, Y Levin, T G F Li, A Libson, T B Littenberg, J Liu, R K L Lo, N A Lockerbie, L T London, J E Lord, M Lorenzini, V Loriette, M Lormand, G Losurdo, J D Lough, C O Lousto, G Lovelace, H Lück, D Lumaca, A P Lundgren, R Lynch, Y Ma, S Macfoy, B Machenschalk, M MacInnis, D M Macleod, I Magaña Hernandez, F Magaña-Sandoval, L Magaña Zertuche, R M Magee, E Majorana, I Maksimovic, N Man, V Mandic, V Mangano, G L Mansell, M Manske, M Mantovani, F Marchesoni, F Marion, S Márka, Z Márka, C Markakis, A S Markosyan, E Maros, F Martelli, L Martellini, I W Martin, D V Martynov, K Mason, A Masserot, T J Massinger, M Masso-Reid, S Mastrogiovanni, A Matas, F Matichard, L Matone, N Mavalvala, N Mazumder, R McCarthy, D E McClelland, S McCormick, L McCuller, S C McGuire, G McIntyre, J McIver, D J McManus, T McRae, S T McWilliams, D Meacher, G D Meadors, J Meidam, E Mejuto-Villa, A Melatos, G Mendell, R A Mercer, E L Merilh, M Merzougui, S Meshkov, C Messenger, C Messick, R Metzdorff, P M Meyers, F Mezzani, H Miao, C Michel, H Middleton, E E Mikhailov, L Milano, A L Miller, A Miller, B B Miller, J Miller, M Millhouse, O Minazzoli, Y Minenkov, J Ming, C Mishra, S Mitra, V P Mitrofanov, G Mitselmakher, R Mittleman, A Moggi, M Mohan, S R P Mohapatra, M Montani, B C Moore, C J Moore, D Moraru, G Moreno, S R Morriss, B Mours, C M Mow-Lowry, G Mueller, A W Muir, Arunava Mukherjee, D Mukherjee, S Mukherjee, N Mukund, A Mullavey, J Munch, E A M Muniz, P G Murray, K Napier, I Nardecchia, L Naticchioni, R K Nayak, G Nelemans, T J N Nelson, M Neri, M Nery, A Neunzert, J M Newport, G Newton, K K Y Ng, T T Nguyen, D Nichols, A B Nielsen, S Nissanke, A Nitz, A Noack, F Nocera, D Nolting, M E N Normandin, L K Nuttall, J Oberling, E Ochsner, E Oelker, G H Ogin, J J Oh, S H Oh, F Ohme, M Oliver, P Oppermann, Richard J Oram, B O'Reilly, R Ormiston, L F Ortega, R O'Shaughnessy, D J Ottaway, H Overmier, B J Owen, A E Pace, J Page, M A Page, A Pai, S A Pai, J R Palamos, O Palashov, C Palomba, A Pal-Singh, H Pan, B Pang, P T H Pang, C Pankow, F Pannarale, B C Pant, F Paoletti, A Paoli, M A Papa, H R Paris, W Parker, D Pascucci, A Pasqualetti, R Passaquieti, D Passuello, B Patricelli, B L Pearlstone, M Pedraza, R Pedurand, L Pekowsky, A Pele, S Penn, C J Perez, A Perreca, L M Perri, H P Pfeiffer, M Phelps, O J Piccinni, M Pichot, F Piergiovanni, V Pierro, G Pillant, L Pinard, I M Pinto, M Pitkin, R Poggiani, P Popolizio, E K Porter, A Post, J Powell, J Prasad, J W W Pratt, V Predoi, T Prestegard, M Prijatelj, M Principe, S Privitera, R Prix, G A Prodi, L G Prokhorov, O Puncken, M Punturo, P Puppo, M Pürrer, H Qi, J Qin, S Qiu, V Quetschke, E A Quintero, R Quitzow-James, F J Raab, D S Rabeling, H Radkins, P Raffai, S Raja, C Rajan, M Rakhmanov, K E Ramirez, P Rapagnani, V Raymond, M Razzano, J Read, T Regimbau, L Rei, S Reid, D H Reitze, H Rew, S D Reyes, F Ricci, P M Ricker, S Rieger, K Riles, M Rizzo, N A Robertson, R Robie, F Robinet, A Rocchi, L Rolland, J G Rollins, V J Roma, R Romano, C L Romel, J H Romie, D Rosińska, M P Ross, S Rowan, A Rüdiger, P Ruggi, K Ryan, S Sachdev, T Sadecki, L Sadeghian, M Sakellariadou, L Salconi, M Saleem, F Salemi, A Samajdar, L Sammut, L M Sampson, E J Sanchez, V Sandberg, B Sandeen, J R Sanders, B Sassolas, B S Sathyaprakash, P R Saulson, O Sauter, R L Savage, A Sawadsky, P Schale, J Scheuer, E Schmidt, J Schmidt, P Schmidt, R Schnabel, R M S Schofield, A Schönbeck, E Schreiber, D Schuette, B W Schulte, B F Schutz, S G Schwalbe, J Scott, S M Scott, E Seidel, D Sellers, A S Sengupta, D Sentenac, V Sequino, A Sergeev, D A Shaddock, T J Shaffer, A A Shah, M S Shahriar, L Shao, B Shapiro, P Shawhan, A Sheperd, D H Shoemaker, D M Shoemaker, K Siellez, X Siemens, M Sieniawska, D Sigg, A D Silva, A Singer, L P Singer, A Singh, R Singh, A Singhal, A M Sintes, B J J Slagmolen, B Smith, J R Smith, R J E Smith, E J Son, J A Sonnenberg, B Sorazu, F Sorrentino, T Souradeep, A P Spencer, A K Srivastava, A Staley, M Steinke, J Steinlechner, S Steinlechner, D Steinmeyer, B C Stephens, R Stone, K A Strain, G Stratta, S E Strigin, R Sturani, A L Stuver, T Z Summerscales, L Sun, S Sunil, P J Sutton, B L Swinkels, M J Szczepańczyk, M Tacca, D Talukder, D B Tanner, M Tápai, A Taracchini, J A Taylor, R Taylor, T Theeg, E G Thomas, M Thomas, P Thomas, K A Thorne, K S Thorne, E Thrane, S Tiwari, V Tiwari, K V Tokmakov, K Toland, M Tonelli, Z Tornasi, C I Torrie, D Töyrä, F Travasso, G Traylor, D Trifirò, J Trinastic, M C Tringali, L Trozzo, K W Tsang, M Tse, R Tso, D Tuyenbayev, K Ueno, D Ugolini, C S Unnikrishnan, A L Urban, S A Usman, H Vahlbruch, G Vajente, G Valdes, M Vallisneri, N van Bakel, M van Beuzekom, J F J van den Brand, C Van Den Broeck, D C Vander-Hyde, L van der Schaaf, J V van Heijningen, A A van Veggel, M Vardaro, V Varma, S Vass, M Vasúth, A Vecchio, G Vedovato, J Veitch, P J Veitch, K Venkateswara, G Venugopalan, D Verkindt, F Vetrano, A Viceré, A D Viets, S Vinciguerra, D J Vine, J-Y Vinet, S Vitale, T Vo, H Vocca, C Vorvick, D V Voss, W D Vousden, S P Vyatchanin, A R Wade, L E Wade, M Wade, R Walet, M Walker, L Wallace, S Walsh, G Wang, H Wang, J Z Wang, M Wang, Y-F Wang, Y Wang, R L Ward, J Warner, M Was, J Watchi, B Weaver, L-W Wei, M Weinert, A J Weinstein, R Weiss, L Wen, E K Wessel, P Weßels, T Westphal, K Wette, J T Whelan, B F Whiting, C Whittle, D Williams, R D Williams, A R Williamson, J L Willis, B Willke, M H Wimmer, W Winkler, C C Wipf, H Wittel, G Woan, J Woehler, J Wofford, K W K Wong, J Worden, J L Wright, D S Wu, G Wu, W Yam, H Yamamoto, C C Yancey, M J Yap, Hang Yu, Haocun Yu, M Yvert, A Zadrożny, M Zanolin, T Zelenova, J-P Zendri, M Zevin, L Zhang, M Zhang, T Zhang, Y-H Zhang, C Zhao, M Zhou, Z Zhou, S J Zhu, X J Zhu, M E Zucker, J Zweizig, S Buchner, I Cognard, A Corongiu, P C C Freire, L Guillemot, G B Hobbs, M Kerr, A G Lyne, A Possenti, A Ridolfi, R M Shannon, B W Stappers, P Weltevrede
We present results from the first directed search for nontensorial gravitational waves. While general relativity allows for tensorial (plus and cross) modes only, a generic metric theory may, in principle, predict waves with up to six different polarizations. This analysis is sensitive to continuous signals of scalar, vector, or tensor polarizations, and does not rely on any specific theory of gravity. After searching data from the first observation run of the advanced LIGO detectors for signals at twice the rotational frequency of 200 known pulsars, we find no evidence of gravitational waves of any polarization...
January 19, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29395995/national-trends-in-tongue-reduction-surgery-for-macroglossia-in-children
#19
Jonathan C Simmonds, Anju K Patel, Nicholas S Mader, Andrew R Scott
OBJECTIVES: To examine the frequency of partial glossectomy performed for the indication of macroglossia in children within the United States, assessing for differences in rates of intervention across various demographics. To identify potential morbidities associated with partial glossectomy in this population and determine how such factors may influence length of stay and cost of admission following tongue reduction surgery. STUDY DESIGN: Retrospective cross-sectional study...
January 4, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29390024/viral-fgarat-orf75a-promotes-early-events-in-lytic-infection-and-gammaherpesvirus-pathogenesis-in-mice
#20
Nick D Van Skike, Nana K Minkah, Chad H Hogan, Gary Wu, Peter T Benziger, Darby G Oldenburg, Mehmet Kara, Deborah M Kim-Holzapfel, Douglas W White, Scott A Tibbetts, Jarrod B French, Laurie T Krug
Gammaherpesviruses encode proteins with homology to the cellular purine metabolic enzyme formyl-glycinamide-phosphoribosyl-amidotransferase (FGARAT), but the role of these viral FGARATs (vFGARATs) in the pathogenesis of a natural host has not been investigated. We report a novel role for the ORF75A vFGARAT of murine gammaherpesvirus 68 (MHV68) in infectious virion production and colonization of mice. MHV68 mutants with premature stop codons in orf75A exhibited a log reduction in acute replication in the lungs after intranasal infection, which preceded a defect in colonization of multiple host reservoirs including the mediastinal lymph nodes, peripheral blood mononuclear cells, and the spleen...
February 1, 2018: PLoS Pathogens
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