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https://www.readbyqxmd.com/read/29452856/generalized-cardiovascular-disease-on-a-preoperative-ct-scan-is-predictive-for-anastomotic-leakage-after-esophagectomy
#1
Alicia S Borggreve, Lucas Goense, Peter S N van Rossum, Richard van Hillegersberg, Pim A de Jong, Jelle P Ruurda
BACKGROUND: Recent studies demonstrated that calcification of arteries supplying the gastric tube is associated with anastomotic leakage after esophagectomy. However, it remains unclear whether this association only derives from local flow limitations, or generalized vascular disease as well. The purpose of this study was to determine whether calcification throughout the entire cardiovascular system is associated with anastomotic leakage. METHODS: Consecutive patients who underwent an esophagectomy with gastric tube reconstruction and cervical anastomosis for esophageal cancer were analyzed...
February 2, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29450741/utility-of-cardiac-computed-tomography-scanning-in-the-diagnosis-and-pre-operative-evaluation-of-patients-with-infective-endocarditis
#2
Jason R Sims, Nandan S Anavekar, Krishnaswamy Chandrasekaran, James M Steckelberg, Walter R Wilson, Bernard J Gersh, Larry M Baddour, Daniel C DeSimone
Transesophageal echocardiography (TEE) is the gold standard imaging study used in the diagnosis of infective endocarditis (IE). Computed tomography angiography (CTA) has undergone rapid advancement as a cardiac imaging technique and has previously shown promise in small non-randomized studies for evaluation of IE. We hypothesized that cardiac CTA would perform similarly to TEE in the detection of endocarditic lesions and that there would be no difference in clinical outcomes whether the coronary arteries were evaluated by CTA or invasive coronary angiography (ICA)...
February 15, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29450719/coronary-plaque-characteristics-on-baseline-ct-predict-the-need-for-late-revascularization-in-symptomatic-patients-after-percutaneous-intervention
#3
Mengmeng Yu, Zhigang Lu, Wenbin Li, Meng Wei, Jing Yan, Jiayin Zhang
OBJECTIVES: To assess pre-procedural plaque characteristics as determined by coronary CT angiography (CCTA) and their associations with late revascularization in symptomatic post-procedural patients. METHODS: Symptomatic patients with pre-procedural CCTA were prospectively enrolled and referred for invasive coronary angiography (ICA). Plaque characterization was performed on the basis of baseline CCTA data. Multivariate logistic regression analysis with a stepwise selection method was performed to identify independent predictors of late revascularization...
February 15, 2018: European Radiology
https://www.readbyqxmd.com/read/29446681/coronary-ct-angiography-use-in-patients-with-chest-pain-presenting-to-emergency-departments
#4
David C Levin, Laurence Parker, Ethan J Halpern, Vijay M Rao
OBJECTIVE: Previously published reports have shown that coronary CT angiography (CCTA) is a more efficient method of diagnosis than myocardial perfusion imaging (MPI) and stress echocardiography for patients presenting to emergency departments (EDs) with acute chest pain. In light of this evidence, the objective of this study was to examine recent trends in the use of these techniques in EDs. MATERIALS AND METHODS: The nationwide Medicare Part B databases for 2006-2015 were the data source...
February 15, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29436255/coronary-tortuosity-is-associated-with-an-elevated-high-sensitivity-c-reactive-protein-concentration-and-increased-risk-of-ischemic-stroke-in-hypertensive-patients
#5
Yang Li, Abdul Qadir Nawabi, Yi Feng, Genshan Ma, Jiayi Tong, Chengxing Shen, Naifeng Liu
Objective The clinical implication of coronary tortuosity is unclear. The present study was conducted to determine the relationships between coronary tortuosity and the high-sensitivity C-reactive protein (hs-CRP) concentration and between coronary tortuosity and cerebrovascular accident in hypertensive patients without coronary artery disease. Methods In total, 236 patients with normal coronary angiography findings were categorized into 3 different groups: control participants (n = 58), who had neither hypertension nor coronary tortuosity; patients with hypertension but no coronary tortuosity (H-NCT group, n = 93); and patients with both hypertension and coronary tortuosity (H-CT group, n = 85)...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29433968/dynamic-stress-computed-tomography-myocardial-perfusion-for-detecting-myocardial-ischemia-a-systematic-review-and-meta-analysis
#6
Minjie Lu, Shuli Wang, Arlene Sirajuddin, Andrew E Arai, Shihua Zhao
BACKGROUND: Comparing to SPECT and MRI, with higher temporal and spatial resolution and development of radiation dose reduction, myocardial computed tomography perfusion has emerged as a potential method for evaluation of hemodynamic myocardial ischemia. This meta-analysis systematically analyzed the performance of dynamic CT myocardial perfusion (DCTMP) to diagnose myocardial ischemia (MI) with clinically established reference methods [MR/SPECT/PET perfusion and fractional flow reserve (FFR)] as the reference standard...
February 10, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29426987/coronary-ct-angiography-in-patients-with-atrial-fibrillation-standard-dose-and-low-dose-imaging-with-a-high-resolution-whole-heart-ct-scanner
#7
Anna Matveeva, Rainer R Schmitt, Karoline Edtinger, Matthias Wagner, Sebastian Kerber, Thomas Deneke, Michael Uder, Sebastian Barth
OBJECTIVE: To compare image quality, observer confidence, radiation exposure in the standard-dose (SD-CCTA) and low-dose (LD-CCTA) protocols of coronary CT angiography (CCTA) in patients with atrial fibrillation (AF). MATERIAL AND METHODS: CCTA was performed in 303 patients using a CT scanner with 16-cm coverage (111 scans during sinus rhythm (SR); 192 during AF). LD-CCTA was used in 218 patients; SD-CCTA in 85 patients suspected of having coronary artery disease (CAD)...
February 9, 2018: European Radiology
https://www.readbyqxmd.com/read/29426687/coronary-manifestations-of-kawasaki-disease-in-computed-tomography-coronary-angiography
#8
Yong Geng Goh, Ching Ching Ong, Grace Tan, Chong Ri Liang, Sanah Merchant Soomar, Chee Wen Terence Lim, Swee Chye Quek, Li San Lynette Teo
Coronary arteritis in Kawasaki disease can lead to serious complications such myocardial infarction and sudden death. The identification of coronary manifestations with a method that is minimally invasive and of low radiation exposure is therefore important in paediatric patients with Kawasaki disease. Coronary CT angiography can be an attractive alternative to invasive coronary angiography. This paper describes imaging techniques for coronary CT angiography in pediatric patients and demonstrates the spectrum of cardiovascular manifestations in patients with Kawasaki disease...
December 11, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29426278/cytochrome-p450-family-4-subfamily-f-member-2-cyp4f2-rs1558139-rs2108622-polymorphisms-and-susceptibility-to-several-cardiovascular-and-cerebrovascular-diseases
#9
Tao Zhang, Kuiying Yu, Xuhua Li
BACKGROUND: Inconsistent conclusions have been reported for the genetic relationship between CYP4F2 (Cytochrome P450 Family 4 Subfamily F Member 2) polymorphisms and the susceptibility to cardiovascular and cerebrovascular diseases. METHODS: We performed a meta-analysis to assess the potential role of rs1558139 C/T and rs2108622 G/A polymorphisms of CYP4F2 in the risks of cardiovascular and cerebrovascular diseases. The retrieval of four databases, including PubMed, Web of Science (WOS), China National Knowledge Infrastructure (CNKI) and WANFANG DATA, was conducted...
February 9, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29422416/incidence-and-predictors-of-lesion-specific-ischemia-by-ffrct-learnings-from-the-international-advance-registry
#10
Hironori Kitabata, Jonathon Leipsic, Manesh R Patel, Koen Nieman, Bernard De Bruyne, Campbell Rogers, Gianluca Pontone, Bjarne L Nørgaard, Jeroen J Bax, Gilbert Raff, Kavitha M Chinnaiyan, Mark Rabbat, Niels Peter Rønnow Sand, Philipp Blanke, Timothy A Fairbairn, Hitoshi Matsuo, Tetsuya Amano, Tomohiro Kawasaki, Yoshihiro Morino, Takashi Akasaka
BACKGROUND: To date, the clinical utility of coronary computed tomography angiography (CTA)-derived fractional flow reserve (FFRCT) has been limited to trials and single center experiences. We herein report the incidence of abnormal FFRCT (≤0.80) and the relationship of lesion-specific ischemia to subject demographics, symptoms, and degree of stenosis in the multicenter, prospective ADVANCE registry. METHODS: One thousand patients with suspected angina having documented coronary artery disease on coronary CTA and clinically referred for FFRCT were prospectively enrolled in the registry...
February 2, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29417250/using-coronary-ct-angiography-for-guiding-invasive-coronary-angiography-potential-role-to-reduce-intraprocedural-radiation-exposure
#11
Christophe T Arendt, Patricia Tischendorf, Julian L Wichmann, Michael Messerli, Lucas Jörg, Niklas Ehl, Robin F Gohmann, Simon Wildermuth, Thomas J Vogl, Ralf W Bauer
OBJECTIVES: We investigated the potential reduction of patient exposure during invasive coronary angiography (ICA) if the procedure had only been directed to the vessel with at least one ≥ 50% stenosis as described in the CT report. METHODS: Dose reports of 61 patients referred to ICA because of at least one ≥ 50% stenosis on coronary CT angiography (CCTA) were included. Dose-area product (DAP) was documented separately for left (LCA) and right coronary arteries (RCA) by summing up the single DAP for each angiographic projection...
February 7, 2018: European Radiology
https://www.readbyqxmd.com/read/29415207/progression-of-calcium-density-in-the-ascending-thoracic-aorta-is-inversely-associated-with-incident-cardiovascular-disease-events
#12
Isac C Thomas, Robyn L McClelland, Matthew A Allison, Joachim H Ix, Erin D Michos, Nketi I Forbang, Wendy S Post, Nathan D Wong, Matthew J Budoff, Michael H Criqui
Aims: Little is known regarding the risk of atherosclerotic cardiovascular disease (ASCVD) conferred by changes in the volume and density of ascending thoracic aorta calcium (ATAC) over time. We evaluated changes in ATAC volume and density scores and incident ASCVD events. Methods and results: The Multi-Ethnic Study of Atherosclerosis is a prospective cohort study of individuals without baseline clinical ASCVD. Ascending thoracic aorta calcium was measured from baseline and follow-up (mean interval 2...
February 5, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29409717/comparison-of-invasively-measured-ffr-with-ffr-derived-from-coronary-ct-angiography-for-detection-of-lesion-specific-ischemia-results-from-a-pc-based-prototype-algorithm
#13
Jens Röther, Maximilian Moshage, Damini Dey, Chris Schwemmer, Monique Tröbs, Florian Blachutzik, Stephan Achenbach, Christian Schlundt, Mohamed Marwan
BACKGROUND: We evaluated the diagnostic accuracy of a novel prototype for on-site determination of CT-based FFR (cFFR) on a standard personal computer (PC) compared to invasively measured FFR in patients with suspected coronary artery disease. METHODS: A total of 91 vessels in 71 patients (mean age 65 ± 9 years) in whom coronary CT angiography had been performed due to suspicion of coronary artery disease, and who subsequently underwent invasive coronary angiography with FFR measurement were analyzed...
January 31, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29408789/automatic-calcium-scoring-in-low-dose-chest-ct-using-deep-neural-networks-with-dilated-convolutions
#14
Nikolas Lessmann, Bram van Ginneken, Majd Zreik, Pim A de Jong, Bob D de Vos, Max A Viergever, Ivana Isgum
Heavy smokers undergoing screening with low-dose chest CT are affected by cardiovascular disease as much as by lung cancer. Low-dose chest CT scans acquired in screening enable quantification of atherosclerotic calcifications and thus enable identification of subjects at increased cardiovascular risk. This paper presents a method for automatic detection of coronary artery, thoracic aorta, and cardiac valve calcifications in low-dose chest CT using two consecutive convolutional neural networks. The first network identifies and labels potential calcifications according to their anatomical location and the second network identifies true calcifications among the detected candidates...
February 2018: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/29406941/cardiac-imaging-modalities-and-appropriate-use
#15
REVIEW
Paul Gabriel Peterson, Michael Berge, John P Lichtenberger, Maureen N Hood, Vincent B Ho
Cardiovascular imaging with calcium scoring computed tomography (CT), coronary CT angiography (CCTA), and cardiac MRI (CMR) have advanced rapidly over recent years. These imaging modalities have increased in availability, accessibility, and clinical practicality due to technological advances allowing for significant radiation dose reduction for high-quality CCTA and for rapid and reliable imaging techniques in CMR. Hardware and software developments are continually increasing efficiency and accuracy of postprocessing...
March 2018: Primary Care
https://www.readbyqxmd.com/read/29404770/high-pitch-low-voltage-ct-coronary-artery-calcium-scoring-with-tin-filtration-accuracy-and-radiation-dose-reduction
#16
Georg Apfaltrer, Moritz H Albrecht, U Joseph Schoepf, Taylor M Duguay, Carlo N De Cecco, John W Nance, Domenico De Santis, Paul Apfaltrer, Marwen H Eid, Chelsea D Eason, Zachary M Thompson, Maximilian J Bauer, Akos Varga-Szemes, Brian E Jacobs, Erich Sorantin, Christian Tesche
OBJECTIVES: To investigate diagnostic accuracy and radiation dose of high-pitch CT coronary artery calcium scoring (CACS) with tin filtration (Sn100kVp) versus standard 120kVp high-pitch acquisition. METHODS: 78 patients (58% male, 61.5±9.1 years) were prospectively enrolled. Subjects underwent clinical 120kVp high-pitch CACS using third-generation dual-source CT followed by additional high-pitch Sn100kVp acquisition. Agatston scores, calcium volume scores, Agatston score categories, percentile-based risk categorization and radiation metrics were compared...
February 5, 2018: European Radiology
https://www.readbyqxmd.com/read/29403300/association-between-il-18-18r-gene-polymorphisms-and-coronary-artery-disease-influence-of-il-18-18r-genetic-variants-on-cytokine-expression
#17
Vadim Mitrokhin, Alexey Nikitin, Olga Brovkina, Dmitry Khodyrev, Alexander Zotov, Nikita Vachrushev, Dmitry Dragunov, Andrey Shim, Mitko Mladenov, Andre Kamkin
Purpose: The present study investigated the influence of IL-18/18R genetic variants on cytokine expression in patients with stable coronary artery disease (CAD). Materials and methods: The polymorphisms rs1946518, rs187238, rs326, rs1169288, and rs183130 were determined in patients with and without CAD. Circulating cytokine levels were measured immunologically. Results: The rs1946518-GG genotype shows higher IL-18 concentration in the group with CAD, but still not significant...
2018: Journal of Inflammation Research
https://www.readbyqxmd.com/read/29402812/contrast-induced-encephalopathy-following-coronary-angiography-with-no-radiological-features-a-case-report-and-literature-review
#18
Abhishek Dattani, Laura Au, Kok Hoon Tay, Patrick Davey
Contrast-induced encephalopathy (CIE) following coronary angiography (CAG) is a very rare complication. Radiological signs such as cerebral oedema and cortical enhancement are of great importance in the diagnosis. We report a case of probable CIE in a 76-year-old gentleman following a normal diagnostic CAG that involved 120 mL of the iodinated contrast agent iohexol (Omnipaque 300). At 90 min postprocedure he became acutely confused with a normal non-contrast CT of the head. After 9 days of conservative treatment, the patient recovered spontaneously with no neurological deficits...
February 2, 2018: Cardiology
https://www.readbyqxmd.com/read/29402736/automated-three-dimensional-tracking-of-the-left-ventricular-myocardium-in-time-resolved-and-dose-modulated-cardiac-ct-images-using-deformable-image-registration
#19
Vikas Gupta, Jonas Lantz, Lilian Henriksson, Jan Engvall, Matts Karlsson, Anders Persson, Tino Ebbers
BACKGROUND: Assessment of myocardial deformation from time-resolved cardiac computed tomography (4D CT) would augment the already available functional information from such an examination without incurring any additional costs. A deformable image registration (DIR) based approach is proposed to allow fast and automatic myocardial tracking in clinical 4D CT images. METHODS: Left ventricular myocardial tissue displacement through a cardiac cycle was tracked using a B-spline transformation based DIR...
February 2, 2018: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/29402323/equivocal-tests-after-contrast-stress-echocardiography-compared-with-invasive-coronary-angiography-or-with-ct-angiography-ct-calcium-score-in-mildly-positive-tests-may-spare-unnecessary-coronary-angiograms
#20
Nicola Gaibazzi, Guido Pastorini, Andrea Biagi, Francesco Tafuni, Claudia Buffa, Silvia Garibaldi, Francesca Boffetti, Giorgio Benatti
BACKGROUND: Imaging stress tests are not ideally accurate to predict anatomically obstructive CAD, leading to a non-trivial rate of unnecessary iCA. This may depend on the threshold used to indicate iCA, and maybe CTA or, one step earlier, CT calcium score could spare most unnecessary iCA in only mildly positive cSE. We assessed the diagnostic accuracy of contrast stress-echocardiography (cSE) in comparison with invasive coronary angiography (iCA), and CT angiography (CTA) only in case of equivocal tests, to find hints helping reduce falsely positive cSE in the suspicion of coronary artery disease (CAD)...
February 6, 2018: Cardiovascular Ultrasound
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