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sclerosing foam

Ronald Bush, Peggy Bush
INTRODUCTION: This study was designed to determine by histological evaluation and clinical correlation the most effective sclerosant concentration of Sotradecol® (sodium tetradecyl sulfate) and Asclera® (polidocanol) for the treatment of leg telangiectasia. METHODS: Histological studies were completed on 40 patients, all of whom were female with a mean age of 53. After sclerotherapy with varying concentrations of sclerosant solutions for the treatment of 0.8 mm and 1 mm leg telangiectasia, histological specimens were examined for the following criteria: luminal changes, subintimal changes, smooth muscle wall alterations, and vessel wall integrity...
October 12, 2016: Phlebology
Lulu Tan, Kaichung Wong, David Connor, Babak Fakhim, Masud Behnia, Kurosh Parsi
OBJECTIVE: To investigate the effect of agitation on foam temperature. METHODS: Sodium tetradecyl sulphate and polidocanol were used. Prior to foam generation, the sclerosant and all constituent equipment were cooled to 4-25℃ and compared with cooling the sclerosant only. Foam was generated using a modified Tessari method. During foam agitation, the temperature change was measured using a thermocouple for 120 s. RESULTS: Pre-cooling all the constituent equipment resulted in a cooler foam in comparison with only cooling the sclerosant...
October 12, 2016: Phlebology
Francesco Ferrara, Giovanni Ferrara, Ermenegildo Furino, Heinrich Ebner, Gennaro Quarto
AIM: The aim of our study was to evaluate the efficacy of a new method of compression sclerotherapy of GSV and SSV. MATERIALS AND METHODS: 345 lower extremities with primary varicose veins, with a long reflux of the GSV (C2-6; Ep; As 2, 3; ± p; Pr), have been submitted to sclerotherapy applying the following method: injection of foam (Polidocanol 2%), or liquid sclerosant (iodate solution 4-6% or Polodocanol 3%) in the trunk of the GSV; echoguided compression of sapheno-femoral junction (performed using an inflatable device, the Safeguard); immediate eccentric positive compression on the trunk of the GSV; and short elastic bandage...
2016: Annali Italiani di Chirurgia
K H Moon, B Dharmarajah, R Bootun, C S Lim, Tra Lane, H M Moore, K Sritharan, A H Davies
OBJECTIVE: Mechanochemical ablation is a novel technique for ablation of varicose veins utilising a rotating catheter and liquid sclerosant. Mechanochemical ablation and radiofrequency ablation have no reported neurological side-effect but the rotating mechanism of mechanochemical ablation may produce microbubbles. Air emboli have been implicated as a cause of cerebrovascular events during ultrasound-guided foam sclerotherapy and microbubbles in the heart during ultrasound-guided foam sclerotherapy have been demonstrated...
August 10, 2016: Phlebology
Ezana Azene, Sally Mitchell, Martin Radvany, Nishant Agrawal, David Eisele, Clifford Weiss
OBJECTIVES/HYPOTHESIS: To assess clinical outcomes of patients with airway venous malformations treated with percutaneous sclerotherapy (VMPS). We highlight the role of foamed bleomycin as a less inflammatory sclerosant and the importance of collaboration between interventional radiology and otolaryngology-head and neck surgery (OHNS). STUDY DESIGN: Retrospective, consecutive, single-center series. METHODS: Sixteen airway VMPS treatment sessions were performed (5 patients)...
July 20, 2016: Laryngoscope
Bibombe P Mwipatayi, Catherine E Western, Jackie Wong, Donna Angel
INTRODUCTION: Skin necrosis is a rare complication of foam sclerotherapy, a common form of treatment for varicose veins. PRESENTATION OF CASE: Both patients presented to the outpatient clinic within 2-14days after foam sclerotherapy with Aethoxysklerol(®) 1%, with severe soft tissue and skin necrosis. Further aggressive treatment of the ulcer was required to resolve the necrosis, resulting in marked residual scar and well granulated leg ulcer respectively. DISCUSSION: Foam sclerotherapy is a common and usually well-tolerated treatment modality for varicose veins...
2016: International Journal of Surgery Case Reports
Mike R Watkins, Richard J Oliver
OBJECTIVES: The objectives were to examine the density, bubble size distribution and durability of sodium tetradecyl sulphate foam and the consistency of production of foam by a number of different operators using the Tessari method. METHODS: 1% and 3% sodium tetradecyl sulphate sclerosant foam was produced by an experienced operator and a group of inexperienced operators using either a 1:3 or 1:4 liquid:air ratio and the Tessari method. The foam density, bubble size distribution and foam durability were measured on freshly prepared foam from each operator...
June 20, 2016: Phlebology
Jean-Luc Gillet, Claudine H Desnos, Michel Lausecker, Christian Daniel, Jean-Jerome Guex, François-André Allaert
OBJECTIVES: An aging population requires evaluation of methods of treatment for older patients. Our objective was to evaluate the indications, practical modalities, safety and tolerability of sclerotherapy in patients 75 years of age and older (group 1) and compare with a control group of patients 18 to74 years of age (group 2). METHOD: This observational, multicentre, prospective and comparative study was conducted by the French Society of Phlebology. Each centre collected in 10 to 20 patients ≥75 years of age and an equal number of patients <75 years of age treated by sclerotherapy, the treatment indication, the patient's personal history, the CEAP clinical class, the type of the veins being treated, the characteristics of sclerotherapy and the complications (immediately after treatment and at one-month follow-up)...
April 11, 2016: Phlebology
S B Patel, A E Ostler, T M Pirie, M S Whiteley
No abstract text is available yet for this article.
January 2014: Journal of Vascular Surgery. Venous and Lymphatic Disorders
Salil B Patel, Alexandra E Ostler, Scott J Dos Santos, Tom M Piriea, Mark S Whiteley
BACKGROUND: Tessari-made foam sclerotherapy is performed around the world in a variety of clinics differing in methods, equipment, temperatures, and altitudes. We investigated how the following factors affected the foam's longevity: silicone vs nonsilicone syringes, volume of foam made, ratio of gas to sclerosant, use of air vs 50:50 mixture of carbon dioxide and oxygen, temperature, altitude, and 10 consecutive reuses of the syringes. METHODS: Sclerosant foam was made by the Tessari double-syringe technique...
July 2015: Journal of Vascular Surgery. Venous and Lymphatic Disorders
Jie Xu, Yi-Fei Wang, An-Wei Chen, Tao Wang, Shao-Hua Liu
This study aimed to develop a modified Tessari method for producing more sclerosing foam in treatment of extensive venous malformations. Sclerosing foam was produced by using Tessari method and the modified Tessari method. The procedure of the later was as follows: prepared foam in a sclerosant-air ratio of 1:4; connected three disposable 10 ml syringes to two medical three-way taps; drawn 4 ml of liquid sclerosant into one syringe and 16 ml averagely of air into the other two; then moved the plungers of all syringes back and forth for 20 times to produce sclerosing foam...
2016: SpringerPlus
Mario Albert Malvehy, Cindy Asbjornsen
This report describes a complication of symptoms consistent with transient ischemic attack following administration of physician-compounded foam sclerotherapy created with room air. After intravenous administration of 8 cc of foam sclerosant prepared with room air and polidocanol using the Tessari method, an otherwise healthy man experienced transient neurologic changes. Immediately following injection of foam, a dense hemiplegia consistent with interruption of the middle cerebral arterial circulation was observed...
January 28, 2016: Phlebology
A A Baeshko, N G Shestak, S S Koryt'ko, K M Kovalevich, V F Vartanian
Foam sclerotherapy is an innovative method of treatment for varicose disease, including its truncal forms, making it possible in outpatient conditions to achieve favourable therapeutic and cosmetic outcomes. Analysed herein are the results of foam sclerotherapy of the great saphenous vein (GSV) and its tributaries in a total of 326 patients presenting with varicose disease of lower limbs (395 GSVs) according to the improved methodology (elevation of the extremity to 60°, crural bandage, use of a cooled sclerosant solution)...
2015: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
Satyendra K Tiwary, Md Zeeshan Hakim, Puneet Kumar, Ajay Kumar Khanna
Angiodysplasia of the gastrointestinal (GI) tract consists of ectasia of the submucosal vessels of the bowel. The evaluation of such patients needs proctoscopy, colonoscopy, small bowel enema, enteroscopy, capsule enteroscopy and angiography. Capsule enteroscopy has come up as an alternative to GI enteroscopy and colonoscopy in patients with occult GI bleeding; up to 52% cases of small bowel angiodysplasia in patients with occult GI bleed with negative upper GI and colonoscopy have been reported. The use of capsule enteroscopy potentially limits the hazard of radiation exposure from angiography and is less invasive than double balloon endoscopy...
2015: BMJ Case Reports
Dario Carugo, Dyan N Ankrett, Vincent O'Byrne, David D I Wright, Andrew L Lewis, Martyn Hill, Xunli Zhang
We have recently reported on the development of a biomimetic vein model to measure the performance of sclerosing foams. In this study we employed the model to compare the commercially-available Varithena(®) (polidocanol injectable foam) 1% varicose vein treatment (referred to as polidocanol endovenous microfoam, or PEM) with physician compounded foams (PCFs) made using different foam generation methods (Double Syringe System and Tessari methods) and different foam formulations [liquid to gas ratios of 1:3 or 1:7; gas mixtures composed of 100% CO2, various CO2:O2 mixtures and room air (RA)]...
November 2015: Journal of Materials Science. Materials in Medicine
Daniel P Friedmann, Ana M Liolios, Douglas C Wu, Mitchel P Goldman, Sasima Eimpunth
BACKGROUND: Although typically mild, transient, and expected, most adverse events (AEs) postsclerotherapy are inflammatory in nature. OBJECTIVE: To evaluate the effects of a high-potency topical corticosteroid (TC) applied immediately postsclerotherapy. MATERIALS AND METHODS: Subjects undergoing bilateral lower extremity sclerotherapy with polidocanol had extremities randomized to a single application of betamethasone dipropionate and placebo saline solutions immediately post-treatment in a double-blind manner...
October 2015: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Cornelis Ma Bruijninckx
Ambulatory ultrasound-guided foam sclerotherapy (UGFS) for refluxing saphenous veins is considered a safe therapy. Venous thromboembolic complications after UGFS as well as after all other ambulatory ablative venous interventions are rarely reported. This paper reports a fatal pulmonary embolism (PE) following UGFS in combination with an extended phlebectomy, and questions what measures should be taken to minimize the risk for thromboembolic complications after these procedures. In the reported case (unsuspected), extensive non-occluding atherosclerosis as well as obesity in combination with use of an oral contraceptive might have contributed to the development of the PE while the use of a β-blocker might have increased its fatal course considerably...
August 2016: Phlebology
Chihiro Itou, Jun Koizumi, Takeshi Hashimoto, Kazunori Myojin, Tatehiro Kagawa, Tetsuya Mine, Yutaka Imai
OBJECTIVE: The purpose of this study was to evaluate the clinical results of the management of gastric varices by balloon-occluded retrograde transvenous obliteration with polidocanol foam versus ethanolamine oleate. MATERIALS AND METHODS: Twenty patients treated with ethanolamine oleate and 21 patients treated with polidocanol foam were enrolled in this study. Early therapeutic effects were assessed mainly by dynamic contrast-enhanced CT. Subjective symptoms, objective findings associated with the procedures, and changes in laboratory data during the obliteration process were evaluated...
September 2015: AJR. American Journal of Roentgenology
Y L Lam, Irwin M Toonder, Cees H A Wittens
OBJECTIVES: The ClariVein® system is an endovenous technique that uses mechano-chemical ablation to treat incompetent truncal veins. This study was conducted to identify the ideal Polidocanol dosage and form for mechano-chemical ablation in order to occlude the great saphenous vein. When adhering to safe dosage levels, sclerosants with higher concentrations potentially limit the extent of treatment. It has been demonstrated that this problem may be overcome by using Polidocanol as a microfoam...
April 2016: Phlebology
S K van der Velden, A A M Biemans, M G R De Maeseneer, M A Kockaert, P W Cuypers, L M Hollestein, H A M Neumann, T Nijsten, R R van den Bos
BACKGROUND: A variety of techniques exist for the treatment of patients with great saphenous vein (GSV) varicosities. Few data exist on the long-term outcomes of these interventions. METHODS: Patients undergoing conventional surgery, endovenous laser ablation (EVLA) and ultrasound-guided foam sclerotherapy (UGFS) for GSV varicose veins were followed up for 5 years. Primary outcome was obliteration or absence of the treated GSV segment; secondary outcomes were absence of GSV reflux, and change in Chronic Venous Insufficiency quality-of-life Questionnaire (CIVIQ) and EuroQol - 5D (EQ-5D™) scores...
September 2015: British Journal of Surgery
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