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Cockett syndrome

Christof T Kaltenmeier, Young Erben, Jeffrey Indes, Alfred Lee, Alan Dardik, Timur Sarac, Cassius Iyad Ochoa Chaar
OBJECTIVE: May-Thurner syndrome (MTS) is increasingly recognized as a frequent source of leg swelling and a precipitating factor for venous thromboembolism. This paper is a systematic review of the English literature on MTS with an analysis focusing on gender differences in presentation and treatment. METHODS: A systematic review of the English literature between April 1967 and December 2014 was performed using the following terms: "May-Thurner syndrome," "Cockett syndrome," and "iliac vein compression syndrome...
December 28, 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
Bilgin Emrecan, Hayati Tastan, Gokhan Yigit Tanrisever, Safak Simsek
Nutcracker syndrome is rarely seen in the young. Most of the symptoms regress during follow-up. Rarely surgical intervention is necessary. This case presentation is unique for being the first case of nutcracker syndrome and coexistent Cockett syndrome that is treated with surgical intervention.
October 2017: Annals of Vascular Surgery
Irfan Ahsan, Binish G Qureshi, Ali Raza Ghani, Faizan Malik, Zulfiqar Arif
May-Thurner syndrome (MTS) also known as Cockett's syndrome is a rare condition responsible for 2%-3% of all cases of deep venous thrombosis (DVT). The thrombosis results from mechanical compression of the left common iliac vein against the body of the fifth lumbar vertebra by the right common iliac artery. Repetitive hyperplasia of the venous wall by compression results in spur formation that in turn causes venous flow obstruction and results in the DVT. Our case is a young female who had acute extensive proximal DVT due to MTS that was successfully managed using mechanical thrombectomy with a venous stent...
April 6, 2017: Clinics and Practice
Leandro Cardarelli-Leite, Fernanda Garozzo Velloni, Priscila Silveira Salvadori, Marcelo Delboni Lemos, Giuseppe D'Ippolito
Abdominal vascular syndromes are rare diseases. Although such syndromes vary widely in terms of symptoms and etiologies, certain imaging findings are characteristic. Depending on their etiology, they can be categorized as congenital-including blue rubber bleb nevus syndrome, Klippel-Trenaunay syndrome, and hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome)-or compressive-including "nutcracker" syndrome, median arcuate ligament syndrome, Cockett syndrome (also known as May-Thurner syndrome), and superior mesenteric artery syndrome...
July 2016: Radiologia Brasileira
Bert Du Pont, Jurgen Verbist, Wouter Van den Eynde, Patrick Peeters
Background Cockett and Thomas described and named Cockett's syndrome in 1965, commonly referred to as iliac vein compression syndrome (IVCS). It is often found as underlying cause in iliofemoral deep venous thrombosis (DVT). They described the syndrome mostly seen on the left side and predominantly in women during the second to the fourth decade of life. In this article, we present a patient with a Cockett's syndrome on the right side. Case presentation Our patient is a 52-year old female with edema of the right leg since 4 months...
April 2016: Acta Chirurgica Belgica
Shantanu Singh, Shivank Singh, Juthika Jyothimallika, Teresa J Lynch
May-Thurner syndrome (MTS) also termed iliocaval compression or Cockett-Thomas syndrome is a common, although rarely diagnosed, condition in which the patient has an anatomical variant wherein the right common iliac artery overlies and compresses the left common iliac vein against the fifth lumbar spine resulting in increased risk of iliofemoral deep venous thrombosis. This variant has been shown to be present in over 23% of the population but most go undetected. We present a patient with MTS who developed high output cardiac failure due to an iatrogenic iliac fistula...
March 16, 2015: World Journal of Clinical Cases
Andreas H Mahnken, Ken Thomson, Michiel de Haan, Gerard J O'Sullivan
Chronic venous insufficiency (CVI) as an advanced stage of chronic venous disease is a common problem that occurs in approximately 1-5 % of the adult population. CVI has either a nonthrombotic (primary) or postthrombotic (secondary) cause involving reflux, obstruction, or a combination of both. The role of venous obstruction is increasingly recognized as a major cause of CVI, with obstructive lesions in the iliocaval segment being markedly more relevant than lesions at the levels of the crural and femoral veins...
August 2014: Cardiovascular and Interventional Radiology
Dian-ning Dong, Xue-jun Wu, Shi-yi Zhang, Zhen-yue Zhong, Xing Jin
OBJECTIVE: To explore the clinical profiles of patients with lower extremity deep venous thrombosis (DVT) complicated with inferior vena cava (IVC) thrombus and summarize their clinical diagnostic and therapeutic experiences. METHODS: The clinical characteristics, diagnosis and treatment of 20 hospitalized patients with DVT complicated with inferior vena cava thrombus were analyzed retrospectively. RESULTS: All of them were of proximal DVT...
June 4, 2013: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Nirvana Sadaghianloo, Elixine Jean-Baptiste, Pierre Haudebourg, Serge Declemy, Aurdlien Mousnier, Rida Hassen-Khodja
Spontaneous rupture of the external iliac vein associated with a May-Thurner syndrome is infrequent, particularly in men. We report a case of previously healthy 73-year-old man with a left iliac vein thrombosis, who presented a large lower left abdominal hematoma of sudden-unset. Emergent laparotomy revealed a 3-cm longitudinal tear in the left external iliac vein, which was repaired primarily. Patient's recovery was uneventful. Possible etiological factors have been identified as venous hypertension due to iliac vein thrombosis associated with Cockett syndrome, as well as inflammatory venous wall...
February 2014: Vascular
Jing Chen, Feng Gao, Jianqiang Chen
OBJECTIVE: To explore the effect of direct multi-slice computed tomography venography (MSCTV) on Cockett's syndrome. METHODS: The imaging features of Cockett's syndrome diagnosed by direct MSCTV were retrospectively analyzed. The iliac vein compression tube segments were reconstructed axially. The ratio of the diameter of the lumen of pressure sections was calculated, and the boundary value was 1:3. According to the deep vein thrombosis, these data were divided into I-III types, the various therapeutic schemes were worked out, and the therapeutic effects were evaluated by the difference in diamete of lower limb before and after the treatment and 6-month follow-up...
January 2013: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
A R Gil Martín, M Carreras Aja, I Arrieta Ardieta, I Labayen Azparren
Iliac vein compression syndrome (also known as May-Thurner syndrome or Cockett's syndrome) is a rare clinical entity in which the left common iliac vein is compressed when it passes between the right common iliac artery and the spine. The sustained compression and trauma caused by the pulsatile force of the artery on the vein damage the intima and lead to the formation of membranes or bands in the vascular lumen that hinder or obstruct the flow of blood in the vein, favoring thrombus formation. The current treatment strategy of choice is endovascular vein patch angioplasty and stenting with the aim of improving the caliber of the lumen and enabling normal venous drainage...
September 2014: Radiología
C Recek
Two myths or dogmas have influenced the therapeutic proceeding of phlebological surgeons in the second half of the 20th century, and both did not stopped to wield their influence up to the present time. The first one is the Cockett's theory of the incompetent calf perforators (blow-out syndrome), the second one is the assertion that femoral vein incompetence invariably causes the most serious stage of chronic venous insufficiency. The incorrectness of the theory of incompetent calf perforators was documented by venous pressure measurements, including direct pressure and electromagnetic flow measurements in the incompetent calf perforators themselves, as well as by plethysmographic results after surgical procedures eliminating the saphenous reflux...
January 2011: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
Guo-Xiang Dong
OBJECTIVE: To explore the surgical treatment of Cockett's syndrome in patients with deep vein thrombosis of lower extremity (DVT). METHODS: Ninety-five patients were diagnosed as Cockett's syndrome among 160 patients with DVT who received surgeries in our hospital from February 1991 to September 2005. Among these 95 patients, pathological changes included left common iliac vein (LCIV) occlusion (n = 20), > 50% stenosis of the LCIV (n = 53), < 50% stenosis (n = 22)...
February 2007: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
Seshadri Raju, Peter Neglen
PURPOSE: Nonthrombotic iliac vein lesions (NIVL), such as webs and spurs described by May and Thurner, are commonly found in the asymptomatic general population. However, the clinical syndrome, variously known as May-Thurner syndrome, Cockett syndrome, or iliac vein compression syndrome, is thought to be a relatively rare contributor of chronic venous disease (CVD), predominantly affecting the left lower extremity of young women. The present study describes the much broader disease profile that has emerged with the use of intravascular ultrasound (IVUS) scanning for diagnosis and analyzes stent placement outcome in two specific NIVL subsets that may offer clues to their pathogenic role...
July 2006: Journal of Vascular Surgery
O Faye, H Darie, S Keita, H T N'diaye, A K Traoré, A Mahé
We present a retrospective study of eight cases of vulvar bilharziasis who attended our institution for dermatological visit from 1998 to 2001. The mean age was 11 years old (range: 7 to 13). The clinical examination found wart like or ulcerated nodules, papules and/or diffuse infiltration. All the lesions were located on the left side of the vulvae (labium) and/or the groin. S. haematobium was the only causative agent identified in all specimens. The exclusive left side location of the lesions reported here has never been mentioned in the previous studies...
May 2006: Bulletin de la Société de Pathologie Exotique
J E Beever, M A Smit, S N Meyers, T S Hadfield, C Bottema, J Albretsen, N E Cockett
Ovine hereditary chondrodysplasia, or spider lamb syndrome (SLS), is a genetic disorder that is characterized by severe skeletal abnormalities and has resulted in substantial economic losses for sheep producers. Here we demonstrate that a non-synonymous T>A transversion in the highly conserved tyrosine kinase II domain of a positional candidate gene, fibroblast growth factor receptor 3 (FGFR3), is responsible for SLS. We also demonstrate that the mutant FGFR3 allele has an additive effect on long-bone length, calling into question the long-standing belief that SLS is inherited as a strict monogenic, Mendelian recessive trait...
February 2006: Animal Genetics
Tae W Chong, Matthew J Bott, John A Kern, Benjamin B Peeler, Curtis G Tribble, Nancy L Harthun
Lower extremity ulcerations that result from venous hypertension are a significant cause of disability in Western nations. Venous ulcers, highly related to lower extremity venous valvular incompetence and post-thrombotic syndrome, demonstrate a protracted course of healing with a high recurrence rate when managed conservatively. Effective treatment includes correcting the elevated lower extremity venous pressure using non-invasive (compression therapy) or invasive modalities (removal or correction of incompetent venous segments, most commonly the greater saphenous vein)...
September 2005: Ostomy/wound Management
G Illuminati, F G Caliò, A D'Urso, P Mancini, V Papaspyropoulos, G Ceccanei, R Lorusso, F Vietri
METHODS: A series of 9 patients of a mean age of 48 years, operated on for compression of the ilio-femoral venous axis is reported. The cause of obstruction was external compression in 3 cases, a retroperitoneal sarcoma in 1 case, and an infrarenal aortic aneurysm in 2. Two patients presented with a Cockett's syndrome, 3 with a chronic ilio-femoral thrombosis, and one with a post-traumatic segmentary stenosis. Treatment consisted in a resection/Dacron grafting of 2 infrarenal aortic aneurysms, one femoro-caval bypass graft, 2 transpositions of the right common iliac artery in the left hypogastric artery for Cockett's syndrome, 3 Palma's operations for chronic thrombosis, and one internal jugular vein interposition for segmentary stenosis...
September 2004: Annali Italiani di Chirurgia
Bernard Planchon, Pierre Pottier
Predisposing clinical features in pregnant women are poorly evaluated in the literature. Several factors are undeniable, for example extrinsic compression of the iliac vein (Cockett syndrome), post phlebitis disease, varicose vein disease, and, for most patients, unquantifiable risk factors. Careful assessment of the overall sensitivity to venous thrombosis, on the basis of history taking (patient and family), will allow better assessment of the predisposition to thromboembolism.
September 2003: Annales de Médecine Interne
No abstract text is available yet for this article.
January 3, 1953: Lancet
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